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Journal Article
Xenobiotica, ISSN 0049-8254, 12/2017, Volume 47, Issue 12, pp. 1027 - 1034
1. TAK-438, vonoprazan fumarate, is a novel orally active potassium-competitive acid blocker, developed as an antisecretory drug. In this study, we... 
oxidation | sulfation | P-CAB | CYP2C19 | CYP3A4 | SULT2A1 | LANSOPRAZOLE | PUMP INHIBITORS | DISEASES | PHARMACOKINETICS | PHARMACOLOGY & PHARMACY | TOXICOLOGY | MONOFUMARATE TAK-438 | HELICOBACTER-PYLORI | Cytochrome P-450 CYP2C19 - metabolism | Pyrroles - pharmacokinetics | Gastrointestinal Agents - pharmacokinetics | Sulfonamides - pharmacokinetics | Index Medicus
Journal Article
Clinical and Translational Gastroenterology, ISSN 2155-384X, 06/2015, Volume 6, Issue 6, pp. e94 - e94
OBJECTIVES: To evaluate safety, tolerability, pharmacokinetics, and pharmacodynamics of TAK-438 (vonoprazan, a potassiumcompetitive acid blocker) in healthy... 
ESOMEPRAZOLE | ARTICLE | HELICOBACTER-PYLORI ERADICATION | GASTROESOPHAGEAL-REFLUX DISEASE | COMPETITIVE ACID BLOCKER | GASTRIC-ACID | PROTON PUMP INHIBITORS | MONOFUMARATE TAK-438 | SUPPRESSION | GASTROENTEROLOGY & HEPATOLOGY | PEPTIC-ULCER | Original Contributions
Journal Article
Journal Article
ALIMENTARY PHARMACOLOGY & THERAPEUTICS, ISSN 0269-2813, 09/2015, Volume 42, Issue 6, pp. 719 - 730
BackgroundProton pump inhibitors (PPIs) are widely used for the treatment of acid-related diseases. Vonoprazan is a member of a new class of acid suppressants;... 
LANSOPRAZOLE | INTRAGASTRIC PH | CYTOCHROME P4502C19 | HELICOBACTER-PYLORI ERADICATION | GASTROESOPHAGEAL-REFLUX DISEASE | GASTRIC-ACID | OMEPRAZOLE | PROTON PUMP INHIBITORS | PHARMACOLOGY & PHARMACY | EXTENSIVE METABOLIZERS | MONOFUMARATE TAK-438 | GASTROENTEROLOGY & HEPATOLOGY
Journal Article
ALIMENTARY PHARMACOLOGY & THERAPEUTICS, ISSN 0269-2813, 02/2016, Volume 43, Issue 3, pp. 442 - 443
Journal Article
Gut, ISSN 0017-5749, 09/2016, Volume 65, Issue 9, pp. 1439 - 1446
ObjectiveThe objective of this study was to assess the efficacy, safety and tolerability of vonoprazan, a novel potassium-competitive acid blocker, as a... 
antibiotic therapy | clinical trials | Helicobacter pylori infection | helicobacter pylori - treatment | CLARITHROMYCIN | LANSOPRAZOLE | MULTICENTER | MANAGEMENT | CLINICAL-TRIAL | PHARMACOKINETICS | JAPAN | INFECTION | MONOFUMARATE TAK-438 | GASTROENTEROLOGY & HEPATOLOGY | AMOXICILLIN | Humans | Middle Aged | Helicobacter Infections - complications | Helicobacter pylori - drug effects | Male | Drug Monitoring - methods | Proton Pump Inhibitors - administration & dosage | Pyrroles - administration & dosage | Helicobacter Infections - drug therapy | Clarithromycin - administration & dosage | Metronidazole - adverse effects | Peptic Ulcer - diagnosis | Pyrroles - adverse effects | Adult | Female | Amoxicillin - administration & dosage | Anti-Bacterial Agents - adverse effects | Helicobacter Infections - diagnosis | Lansoprazole - administration & dosage | Proton Pump Inhibitors - adverse effects | Double-Blind Method | Drug Administration Schedule | Clarithromycin - adverse effects | Metronidazole - administration & dosage | Treatment Outcome | Drug Therapy, Combination - methods | Lansoprazole - adverse effects | Sulfonamides - adverse effects | Amoxicillin - adverse effects | Helicobacter pylori - isolation & purification | Anti-Bacterial Agents - administration & dosage | Peptic Ulcer - drug therapy | Breath Tests - methods | Peptic Ulcer - etiology | Sulfonamides - administration & dosage | Usage | Safety and security measures | Research | Helicobacter pylori | Antacids | Index Medicus | Abridged Index Medicus | Helicobacter Pylori | HELICOBACTER PYLORI - TREATMENT | CLINICAL TRIALS | 1506 | ANTIBIOTIC THERAPY | HELICOBACTER PYLORI INFECTION
Journal Article
DIGESTIVE DISEASES AND SCIENCES, ISSN 0163-2116, 03/2017, Volume 62, Issue 3, pp. 739 - 745
Vonoprazan (VPZ) is a new oral potassium-competitive acid blocker that has recently become available. The aim of this study was to investigate the effects of... 
LANSOPRAZOLE | DIAGNOSIS | Vonoprazan | PROTON-PUMP INHIBITOR | RANDOMIZED CLINICAL-TRIAL | OMEPRAZOLE | ACCURACY | THERAPY | Helicobacter pylori | INFECTION | MONOFUMARATE TAK-438 | GASTROENTEROLOGY & HEPATOLOGY | Urea breath test | RANITIDINE
Journal Article
Journal Article
Journal Article
World Journal of Gastroenterology, ISSN 1007-9327, 04/2018, Volume 24, Issue 14, pp. 1550 - 1561
Journal Article