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Journal of Medicinal Chemistry, ISSN 0022-2623, 10/2010, Volume 53, Issue 19, pp. 7202 - 7218
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 04/2004, Volume 126, Issue 16, pp. 5154 - 5163
A new class of phosphate and phosphonate prodrugs, called HepDirect prodrugs, is described that combines properties of rapid liver cleavage with high plasma... 
IN-VITRO | PHOSPHONATES | CYCLOPHOSPHAMIDE | PHOSPHATE-ESTERS | BIOLOGICAL EVALUATION | INTRACELLULAR DELIVERY | ANTIVIRAL ACTIVITY | HEPATITIS-B | DERIVATIVES | CHEMISTRY, MULTIDISCIPLINARY | 5'-MONOPHOSPHATE
Journal Article
Current Pharmaceutical Design, ISSN 1381-6128, 2017, Volume 23, Issue 45, pp. 6984 - 7002
Journal Article
CURRENT PHARMACEUTICAL DESIGN, ISSN 1381-6128, 2017, Volume 23, Issue 45, pp. 6984 - 7002
Background: Modified nucleoside and nucleotide analogs are now the cornerstone of antiviral and anticancer chemotherapies. However, these compounds are not... 
prodrug | enzyme | Antiviral agents | DEPENDENT RNA-POLYMERASE | nucleoside | HUMAN LYMPHOID-CELLS | CLINICAL PHARMACOKINETICS | TENOFOVIR DISOPROXIL FUMARATE | IN-VITRO | HEPATITIS-C VIRUS | ADEFOVIR DIPIVOXIL | ORAL BIOAVAILABILITY | ANTIVIRAL ACTIVITY | PHARMACOLOGY & PHARMACY | INTRACELLULAR ACTIVATION | monophosphate | triphosphate
Journal Article
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 09/2012, Volume 22, Issue 18, pp. 5924 - 5929
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 06/2015, Volume 58, Issue 11, pp. 4822 - 4838
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 2010, Volume 20, Issue 24, pp. 7376 - 7380
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 07/2017, Volume 60, Issue 14, pp. 6077 - 6088
Journal Article
Molecular Endocrinology, ISSN 0888-8809, 07/2015, Volume 29, Issue 7, pp. 988 - 1005
Journal Article
Journal of Chromatography A, ISSN 0021-9673, 11/2019, Volume 1606, pp. 460379 - 460379
•Hexylamine in the wash solvent reduces carryover for monophosphate containing compounds.•Metal free columns reduce the carryover for monophosphate containing... 
Carryover | Liquid chromatography-tandem mass spectrometry | PEEK tubing | Monophosphate prodrugs | PHOSPHORYLATED PEPTIDES | CHEMISTRY, ANALYTICAL | ACID | HYDROPHILIC INTERACTION | PERFORMANCE | BIOCHEMICAL RESEARCH METHODS | SUPPRESSION | QUANTITATIVE-ANALYSIS