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Thermochimica Acta, ISSN 0040-6031, 2011, Volume 524, Issue 1, pp. 194 - 196
► Two-stage proton ionizations for three N-substituted sulfonic acid derivatives of morpholine. ► Δ and Δ in = 0–0.360 measured for MOPS, MOBS and MOPSO. ► In... 
MOPSO | MOPS | Proton ionization | Calorimetry | MOBS | GLYCINE | CHEMISTRY, ANALYTICAL | THERMODYNAMIC QUANTITIES | COMPONENTS | CHEMISTRY, PHYSICAL | 2ND DISSOCIATION | PHYSIOLOGICAL PH | 55-DEGREES-C | 5-DEGREES-C | BUFFERS | N-TRIS(HYDROXYMETHYL)METHYLGLYCINE TRICINE | DISSOCIATION-CONSTANTS | Ionization | Chemical properties
Journal Article
FEBS Letters, ISSN 0014-5793, 05/2014, Volume 588, Issue 9, pp. 1537 - 1541
Cytochrome ubiquinol oxidase uses the electron transport from ubiquinol to oxygen to establish a proton gradient across the membrane. The enzyme complex... 
Ubiquinol cytochrome bd oxidase | CydX | UV/vis difference spectroscopy | Escherichia coli | CydAB | oxidase | MOPS | CBB | isopropyl β | 3-(N-morpholino)propanesulfonic acid | Ubiquinol cytochrome | 1-thiogalactopyranoside | phenylmethylsulfonyl fluoride | DDM | dodecyl β | maltoside | PMSF | IPTG | Coomassie Brilliant Blue R-250 | RESPIRATORY-CHAIN | COMPLEX | MECHANISM | DIRECTED MUTAGENESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | BIOPHYSICS | D TERMINAL OXIDASE | OXYGEN REDUCTASES | PROTEINS | BINDING SITE | Amino Acid Sequence | Catalytic Domain | Cytochromes - chemistry | Escherichia coli - enzymology | Protein Multimerization | Enzyme Stability | Molecular Sequence Data | Electron Transport Chain Complex Proteins - isolation & purification | Protein Subunits - biosynthesis | Electron Transport Chain Complex Proteins - chemistry | Escherichia coli Proteins - isolation & purification | Oxidoreductases - chemistry | Cytochromes - biosynthesis | Oxidoreductases - isolation & purification | Chromatography, Affinity | Cytochromes - isolation & purification | Protein Subunits - isolation & purification | Escherichia coli Proteins - biosynthesis | Electron Transport Chain Complex Proteins - biosynthesis | Protein Subunits - chemistry | Escherichia coli Proteins - chemistry | Oxidoreductases - biosynthesis | Oxidases | Heme
Journal Article
Biotechnology Reports, ISSN 2215-017X, 12/2019, Volume 24, p. e00372
Cytochrome P450 enzymes are a promising tool for the late-stage diversification of lead drug candidates and can provide an alternative route to structural... 
N-demethylation | Biocatalysis | Hydroxylation | Cytochrome P450 | Site-directed mutagenesis
Journal Article
Redox Biology, ISSN 2213-2317, 07/2018, Volume 17, pp. 207 - 212
The aim of this work was to develop a cryopreservation method of small liver biopsies for in situ mitochondrial function assessment. Herein we describe a... 
Mitochondria | Oxygen consumption rate | High-resolution respirometry | Cryopreservation | Biopsy | Mitochondrial function | OXIDATIVE-PHOSPHORYLATION | CELLS | PEROXYNITRITE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHAIN | BRAIN MITOCHONDRIA | FIBERS | DYSFUNCTION | TISSUES
Journal Article
Translational Research, ISSN 1931-5244, 2016, Volume 177, pp. 19 - 30.e5
Nontransferrin-bound iron (NTBI) is a heterogeneously speciated plasma iron, typically detectable when transferrin saturation (TfSat) exceeds 75%. Here, we... 
Internal Medicine | THALASSEMIA PATIENTS | MEDICINE, RESEARCH & EXPERIMENTAL | QUANTIFICATION | CA2+ CHANNELS | LABILE PLASMA IRON | MEDICINE, GENERAL & INTERNAL | T2-ASTERISK-MAGNETIC RESONANCE | CHELATION-THERAPY | LIVER | MEDICAL LABORATORY TECHNOLOGY | OVERLOAD CARDIOMYOPATHY | CHELATABLE IRON | HEMOCHROMATOSIS | Microspheres | Nitrilotriacetic Acid - metabolism | Regression Analysis | Iron Chelating Agents - pharmacology | Humans | Fluorescence | Biological Assay - methods | Transferrin - metabolism | Iron - metabolism | Medical colleges | Transferrin | Hospitals | Research institutes | CSA, congenital sideroblastic anemia | CI, confidence interval | UV, ultraviolet | AlAT, alanine-aminotransferase | MOPS, 3-(N-morpholino)propanesulfonic acid | MDS, myelodysplastic syndrome | ELISA, enzyme-linked immunosorbent assay | DFP, deferiprone | ULN, upper limit of normal | DBA, Diamodn-Blackfan anemia | DCI, directly chelatable iron | SD, standard deviation | DFX, deferasirox | Tf, transferrin | NTA, nitrilotriacetic acid | LPI, labile plasma iron | CIC, cardiac iron content | IQR, interquartile range | TfSat, transferrin saturation | NTBI, nontransferrin-bound iron | SF, serum ferritin | LIC, liver iron content | CFBs, control fluorescent beads | f.c., final concentration | DFO, deferoxamine | sTfR, soluble transferrin receptors | AAS, atomic absorption standard | Original | FBC, full blood count | NRBC, nucleated red blood cells
Journal Article
Redox Biology, ISSN 2213-2317, 06/2018, Volume 16, pp. 294 - 302
Chronic obstructive pulmonary disease (COPD) and cystic fibrosis (CF) are lethal pulmonary diseases. Cigarette consumption is the main cause for development of... 
Cystic fibrosis | Mitochondria | Cigarette smoke extract | CFTR | ROS | COPD | KAPPA-B ACTIVATION | OXIDATIVE STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | COMPLEX I DEFICIENCY | CHLORIDE ANION | CONDUCTANCE REGULATOR CFTR | EPITHELIAL-CELLS | EXPRESSION | EXPOSURE | CYSTIC-FIBROSIS GENE | C-SRC
Journal Article
Protein Science, ISSN 0961-8368, 09/2005, Volume 14, Issue 9, pp. 2246 - 2257
Journal Article
Journal Article
Human Vaccines & Immunotherapeutics, ISSN 2164-5515, 02/2015, Volume 11, Issue 2, pp. 458 - 467
Variations of post-translational modifications are important for stability and in vivo behavior of therapeutic antibodies. A recombinant humanized anti-cocaine... 
Endo Lys-C, lysyl endoproteinase | CHO, Chinese hamster ovary | D | cocaine | h2E2, humanized monoclonal antibody against cocaine | mAb, monoclonal antibody | MOPS, 3-(N-morpholino)propanesulfonic acid | Fc, fragment, crystallizable | TBP, tributylphosphine | dissociation constant | K | ELISA, enzyme-linked immunosorbent assay | HPLC, high performance liquid chromatography | NEPHGE, non-equilibrium pH gel electrophoresis | antigen-binding | SCX, strong cation exchange | fluorescence quenching, heterogeneity | ligand binding | Fab fragment | TBS, tris-buffered saline | non-equilibrium pH gel electrophoresis | BE, benzoylecgonine | Endo H, endoglycosidase H | Fab, fragment | IEF, isoelectric focusing | ABD-F, 7-fluorobenz-2-oxa-1, 3-diazole-4-sulfonamide | CE, cocaethylene | PNGase-F, peptide N-glycosidase F | CDR, complementarity determining regions | high performance ion exchange chromatography | MES, 2-(N-morpholino)ethanesulfonic acid | monoclonal antibody | ADCC, antibody-dependent cell mediated cytotoxicity | High performance ion exchange chromatography | Heterogeneity | Ligand binding | Non-equilibrium pH gel electrophoresis | Cocaine | Monoclonal antibody | Fluorescence quenching | fluorescence quenching | IGG MOLECULES | IMMUNOLOGY | heterogeneity | LC-MS | LIQUID-CHROMATOGRAPHY | REDUCTION | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | 4-(AMINOSULFONYL)-7-FLUORO-2,1,3-BENZOXADIAZOLE | PROTEINS | CHEMICAL-MODIFICATIONS | BRAIN | Humans | Recombinant Proteins - chemistry | Immunoglobulin Fab Fragments - isolation & purification | Antibodies, Monoclonal - isolation & purification | Fluorometry | Static Electricity | Cocaine - analogs & derivatives | Cocaine - immunology | Recombinant Proteins - isolation & purification | Recombinant Proteins - immunology | Antibodies, Monoclonal, Humanized - isolation & purification | Immunoglobulin Fab Fragments - chemistry | Chemical Phenomena | Disulfides - analysis | Glucans - analysis | Protein Binding | Immunoglobulin Fab Fragments - immunology | Antibodies, Monoclonal, Humanized - immunology | Antibodies, Monoclonal - chemistry | Antibodies, Monoclonal - immunology | Antibodies, Monoclonal, Humanized - chemistry
Journal Article
Molecular & Biochemical Parasitology, ISSN 0166-6851, 04/2010, Volume 170, Issue 2, pp. 93 - 99
Journal Article
Experimental Parasitology, ISSN 0014-4894, 2008, Volume 119, Issue 3, pp. 391 - 397
We examined the effects of tick SGx and saliva on basal- and platelet-derived growth factor (PDGF)-stimulated cell migration and extracellular signal-regulated... 
Dermacentor variabilis | MOPS | extracellular signal-regulated kinase | HB-EGF | DMSO | dimethylsulfoxide | JNK | 3- N(morpholino)propanesulfonic acid | platelet-derived growth factor | phosphate-buffered saline | MTS | Signal transduction | fibroblast growth factor | FBS | ethylenediaminetetraacetic acid | Fibroblasts | PBS | 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium | keratinocyte growth factor | FGF | SGx | MAPK | p38 MAPK | Hank’s balanced salt solution | fetal bovine serum | focal adhesion kinase | PACE | epidermal growth factor | Cell migration | ERK | ELISA | Jun amino-terminal kinase | Dulbecco’s modified Eagle’s medium | Tick feeding lesion | mitogen-activated protein kinase | DMEM | phosphoantibody cell-based ELISA | transforming growth factor α | EGF | VEGF | DMEM/F12 | KGF | EDTA | heparin binding EGF-like growth factor | opossum kidney | FAK | salivary gland extract | Dulbecco’s modified Eagle’s medium/F12 medium | PDGF | vascular endothelial growth factor | enzyme-linked immunosorbent assay | TGFα | p38 mitogen-activated protein kinase | HBSS | Dulbecco's modified Eagle's medium | 3-N(morpholino)propanesulfonic acid | Dulbecco's modified Eagle's medium/F12 medium | Hank's balanced salt solution | OK | PATHWAYS | ACTIVATED PROTEIN-KINASE | signal transduction | INVOLVEMENT | BRAZIL | fibroblasts | CELL-MIGRATION | cell migration | GROWTH-FACTOR | INHIBITOR | BITE LESIONS | tick feeding lesion | PARASITOLOGY | Rabbits | Fibroblasts - physiology | Male | Salivary Glands - physiology | Dermacentor - chemistry | Extracellular Signal-Regulated MAP Kinases - metabolism | Saliva - chemistry | Cell Movement - physiology | Saliva - physiology | Salivary Glands - chemistry | Dermacentor - physiology | Cell Movement - drug effects | Animals | Female | Fibroblasts - cytology | Mice | 3T3 Cells | Protein kinases | Growth factors | Anticoagulants (Medicine)
Journal Article