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Nucleic acids research, ISSN 1362-4962, 2017, Volume 45, Issue 1, pp. 395 - 416
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2016, Volume 11, Issue 4, p. e0154390
Journal Article
Journal Article
Stem cells translational medicine, ISSN 2157-6564, 2016, Volume 5, Issue 2, pp. 152 - 163
A human spinal muscular atrophy (SMA)‐derived induced pluripotent stem cell (iPSC) disease model was established. The neural differentiation of SMA‐iPSCs... 
Induced pluripotent stem cells | Thyrotropin-releasing hormone | Glycogen synthase kinase-3 | Survival motor neuron protein | Spinal muscular atrophy | SURVIVAL | PHENOTYPES | HIPPOCAMPAL-NEURONS | MOTOR-NEURON PROTEIN | CELL & TISSUE ENGINEERING | IN-VITRO | TRH ANALOG | MOUSE MODEL | DISEASE | DIFFERENTIATION | SMN GENE | Apoptosis - drug effects | Skin - metabolism | Humans | Transcriptional Activation | Astrocytes - pathology | Spine - metabolism | Child, Preschool | Glycogen Synthase Kinase 3 beta | Spine - drug effects | Survival of Motor Neuron 2 Protein - metabolism | Motor Neurons - pathology | Muscular Atrophy, Spinal - genetics | Survival of Motor Neuron 2 Protein - genetics | Survival of Motor Neuron 1 Protein - genetics | Thyrotropin-Releasing Hormone - therapeutic use | Female | Thyrotropin-Releasing Hormone - analogs & derivatives | Spine - pathology | Motor Neurons - drug effects | Skin - pathology | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism | Induced Pluripotent Stem Cells - pathology | Astrocytes - drug effects | Gene Expression | Muscular Atrophy, Spinal - metabolism | Induced Pluripotent Stem Cells - drug effects | Signal Transduction | Glycogen Synthase Kinase 3 - antagonists & inhibitors | Survival of Motor Neuron 1 Protein - metabolism | Fibroblasts - pathology | Glycogen Synthase Kinase 3 - metabolism | Muscular Atrophy, Spinal - pathology | Motor Neurons - metabolism | Glycogen Synthase Kinase 3 - genetics | Cell Differentiation - drug effects | Models, Biological | Fibroblasts - drug effects | Muscular Atrophy, Spinal - drug therapy | Primary Cell Culture | Survival of Motor Neuron 2 Protein - agonists | Skin - drug effects | Astrocytes - metabolism | Motor neurons | Data analysis | Neurons | Menopause | Clinical trials | Kinases | Patients | Studies | Atrophy | Proteins | Ethics | Thyroid-stimulating hormone | Stem cells | Fibroblasts | Motion capture | Alzheimers disease | Pluripotency | Age | Apoptosis | Inhibitory postsynaptic potentials | Cell-Based Drug Development, Screening, and Toxicology
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2012, Volume 109, Issue 15, pp. 5803 - 5808
Journal Article
Nature neuroscience, ISSN 1546-1726, 2006, Volume 9, Issue 3, pp. 408 - 419
Neurodegenerative diseases can have long preclinical phases and insidious progression patterns, but the mechanisms of disease progression are poorly... 
UBIQUITIN-PROTEASOME SYSTEM | ALZHEIMERS-DISEASE | MUSCLE-FIBERS | LINKED SOD1 MUTANTS | ALS MICE | AMYOTROPHIC-LATERAL-SCLEROSIS | MOTOR-NEURON DISEASE | MUTANT SUPEROXIDE-DISMUTASE | CILIARY NEUROTROPHIC FACTOR | TRANSGENIC MOUSE MODEL | NEUROSCIENCES | Superoxide Dismutase - genetics | Synaptic Vesicles - metabolism | Neuromuscular Junction - metabolism | Humans | Nerve Degeneration - physiopathology | Nerve Degeneration - genetics | Muscle, Skeletal - innervation | Motor Neurons - pathology | Neuronal Plasticity - genetics | Motor Neuron Disease - genetics | Muscle Fatigue - drug effects | Motor Neuron Disease - drug therapy | Motor Neuron Disease - physiopathology | Ciliary Neurotrophic Factor - pharmacology | Motor Neurons - drug effects | Disease Models, Animal | Genetic Predisposition to Disease - genetics | Synaptic Vesicles - ultrastructure | Axons - drug effects | Axons - metabolism | Ciliary Neurotrophic Factor - therapeutic use | Mice, Transgenic | Mutation - genetics | Neuromuscular Junction - ultrastructure | Motor Neurons - metabolism | Animals | Muscle Fibers, Fast-Twitch - physiology | Muscle Fibers, Slow-Twitch - physiology | Axons - pathology | Muscle, Skeletal - physiopathology | Muscle Fatigue - genetics | Mice | Superoxide Dismutase-1 | Nerve Degeneration - drug therapy | Axons | Brain research | Physiological aspects | Nervous system | Degeneration | Research | Ciliary neurotrophic factor | Identification and classification
Journal Article