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Journal Article
Blood, ISSN 0006-4971, 09/2015, Volume 126, Issue 13, pp. 1565 - 1574
Mantle cell lymphoma (MCL) cells exhibit increased B-cell receptor and nuclear factor (NF)-kappa B activities. The bromodomain and extra-terminal (BET) protein... 
SELECTIVE-INHIBITION | BRUTONS TYROSINE KINASE | EMERGING ROLES | BTK | MECHANISMS | HEMATOLOGY | NF-KAPPA-B | CANCER | BROMODOMAIN | P-TEFB | BRD4 | Cyclin-Dependent Kinase 6 - antagonists & inhibitors | Pyrazoles - therapeutic use | Protein-Tyrosine Kinases - metabolism | Humans | Lymphoma, Mantle-Cell - pathology | NF-kappa B - metabolism | Antineoplastic Agents - therapeutic use | Proto-Oncogene Proteins c-bcl-2 - metabolism | Antineoplastic Agents - pharmacology | Cyclin-Dependent Kinase 4 - antagonists & inhibitors | Lymphoma, Mantle-Cell - metabolism | Pyrazoles - pharmacology | Triazoles - therapeutic use | Enzyme Inhibitors - pharmacology | Lymphoma, Mantle-Cell - drug therapy | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Cyclin-Dependent Kinase 6 - metabolism | Pyrimidines - pharmacology | Cyclin-Dependent Kinase 4 - metabolism | Mice, SCID | Enzyme Inhibitors - therapeutic use | Proto-Oncogene Proteins c-myc - metabolism | Azepines - therapeutic use | Azepines - pharmacology | Drug Synergism | Transcription Factors - metabolism | Triazoles - pharmacology | Animals | Transcription Factor RelA - metabolism | Pyrimidines - therapeutic use | Nuclear Proteins - antagonists & inhibitors | Cell Line, Tumor | Histone Deacetylase Inhibitors - pharmacology | Mice, Inbred NOD | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Cell Proliferation - drug effects | Histone Deacetylase Inhibitors - therapeutic use | Drug Resistance, Neoplasm - drug effects | Index Medicus | Abridged Index Medicus | Lymphoid Neoplasia
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2003, Volume 100, Issue 14, pp. 8164 - 8169
Overexpression of c-Myc is one of the most common alterations in human cancers, yet it is not clear how this transcription factor acts to promote malignant... 
Biological Sciences | Transcription factors | Genes | DNA | Genomics | Cell lines | Burkitt lymphoma | Genomes | Gene expression | General transcription factors | Binding sites | YEAST | TRANSFORMATION | TATA-BINDING PROTEIN | DNA-BINDING | ONCOGENE | GENE | MULTIDISCIPLINARY SCIENCES | SACCHAROMYCES-CEREVISIAE | ASSOCIATION | TUMORIGENESIS | TRANSGENIC MICE | Translocation, Genetic | Oligonucleotide Array Sequence Analysis | Humans | Neoplasm Proteins - physiology | Gene Expression Regulation, Neoplastic | Gene Expression Profiling | Genes, myc | Promoter Regions, Genetic - genetics | RNA, Messenger - biosynthesis | Proto-Oncogene Proteins c-myc - physiology | Cell Transformation, Neoplastic - genetics | Burkitt Lymphoma - genetics | Transcription, Genetic | Dimerization | DNA-Binding Proteins - physiology | RNA, Messenger - genetics | Burkitt Lymphoma - metabolism | Neoplasm Proteins - chemistry | Transcription Factor TFIID - physiology | Tumor Cells, Cultured - metabolism | DNA-Binding Proteins - chemistry | Protein Interaction Mapping | RNA, Neoplasm - biosynthesis | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors | RNA, Neoplasm - genetics | Transcription Factors | Proto-Oncogene Proteins c-myc - chemistry | Basic-Leucine Zipper Transcription Factors | Genetic aspects | Research | Genetic regulation | Cancer cells | Lymphatic system | Cells | Index Medicus
Journal Article
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 09/2017, Volume 139, Issue 36, pp. 12450 - 12458
Journal Article
The Journal of Pathology, ISSN 0022-3417, 07/2017, Volume 242, Issue 3, pp. 309 - 321
Primary effusion lymphoma ( PEL ) is a rare and aggressive B‐cell lymphoma with a dismal prognosis caused by infection of Kaposi's sarcoma‐associated... 
KSHV | compound C | primary effusion lymphoma | sirtuins | AMPK | ) | therapeutic target | 5' adenosine monophosphate‐activated protein kinase | tenovin‐6 | SIRT1 | Kaposi's sarcoma‐associated herpesvirus | tenovin-6 | 5' adenosine monophosphate-activated protein kinase (AMPK) | Kaposi's sarcoma-associated herpesvirus (KSHV) | APOPTOSIS | ACTIVATED PROTEIN-KINASE | SARCOMA-ASSOCIATED HERPESVIRUS | DNA-DAMAGE | PATHOLOGY | P53 | INHIBITION | ONCOLOGY | TUMOR-SUPPRESSOR | LEUKEMIA | CELLULAR-TRANSFORMATION | Phosphorylation - physiology | AMP-Activated Protein Kinases - metabolism | MAP Kinase Signaling System - physiology | Cell Proliferation - physiology | Cell Cycle Checkpoints - physiology | Lymphoma, Primary Effusion - enzymology | Mice, SCID | Sirtuin 1 - antagonists & inhibitors | Gene Knockdown Techniques | Dose-Response Relationship, Drug | AMP-Activated Protein Kinases - physiology | Animals | Lymphoma, Primary Effusion - physiopathology | Sirtuin 1 - physiology | Mice, Inbred NOD | Antineoplastic Agents - pharmacology | Benzamides - pharmacology | Apoptosis - physiology | Cell Survival - physiology | Lymphomas | Sarcoma | Adenylic acid | Tumor proteins | Muscle proteins | Analysis | Cell proliferation | Phosphorylation | Prognosis | Transcription | Genes | Cytotoxicity | Activation | Infections | Pathways | Copyrights | Cell cycle | Inhibition | Primary effusion lymphoma | Cell survival | Effusion | Pharmacology | Chemical compounds | Patients | Survival | SIRT1 protein | Lymphoma | Inhibitors | Lymphocytes B | Kaposi's sarcoma | Medical prognosis | Mice | Apoptosis | B-cell lymphoma | Index Medicus | Tenovin-6 | Compound C | Kaposi’s sarcoma-associated herpesvirus (KSHV) | 5′ adenosine monophosphate-activated protein kinase (AMPK)
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2018, Volume 115, Issue 47, pp. 12034 - 12039
Journal Article
Journal Article
Toxicological Sciences, ISSN 1096-6080, 05/2018, Volume 163, Issue 1, pp. 214 - 225
Abstract TEMPO (2, 2, 6, 6-tetramethylphiperidine-1-oxyl) and its derivatives are stable free radical nitroxides widely used in the field of chemistry,... 
Nitroxide | Mouse lymphoma assay | DNA damage | Loss of heterozygosity | Benchmark dose | EMPIRICAL-ANALYSIS | ASSAY | DOSE-RESPONSE | DNA-DAMAGE | mouse lymphoma assay | PIPERIDINE NITROXIDE TEMPOL | FREE-RADICALS | IN-VITRO | MUTATIONAL SPECTRA | BMD METRICS | HEPG2 CELLS | benchmark dose | nitroxide | TOXICOLOGY | loss of heterozygosity | Index Medicus
Journal Article
DENTAL MATERIALS, ISSN 0109-5641, 03/2018, Volume 34, Issue 3, pp. 519 - 530
Objectives. Camphorquinone (CQ) is the most important photoinitiator used in dental composite resins. Sparse data indicate a mutagenic potential of CQ.... 
Oxidative stress | MATERIALS SCIENCE, BIOMATERIALS | OXIDATIVE DNA-DAMAGE | COMET ASSAY | PHOTOSENSITIZERS | COMPOSITES | FIBROBLAST-CULTURES | IN-VITRO | DENTISTRY, ORAL SURGERY & MEDICINE | MUTATION | Mouse lymphoma cells | Mutagenicity | RESIN POLYMERIZATION INITIATORS | STRESS | CYTOTOXICITY | Camphorquinone
Journal Article