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1. Full Text Mononuclear phagocyte diversity in the intestine
by Bogunovic, Milena and Mortha, Arthur and Muller, Paul Andrew and Merad, Miriam
Immunologic Research, ISSN 0257-277X, 12/2012, Volume 54, Issue 1, pp. 37 - 49
Present in all organs, mononuclear phagocytes consist of a heterogeneous population of hematopoietic cells whose main role is to ensure tissue homeostasis... 
Allergology | Immunology | Dendritic cells (DCs) | Medicine & Public Health | Intestine | Mucosa | Lamina propria | Internal Medicine | Macrophages | Medicine/Public Health, general | Mononuclear phagocytes (MPs) | Muscularis | POSTOPERATIVE ILEUS | RETINOIC-ACID | BONE-MARROW | LAMINA-PROPRIA | IMMUNOLOGY | CHRONIC ENTEROCOLITIS | INFLAMMATORY-BOWEL-DISEASE | IN-VIVO | REGULATORY T-CELLS | STEADY-STATE | CD103(+) DENDRITIC CELLS | Phagocytes - cytology | Animals | Phagocytes - immunology | Intestinal Mucosa - immunology | Humans | Antigens | Pathology | Bacteria | Cellular biology | Digestive system
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2. Full Text Comparative genomics analysis of mononuclear phagocyte subsets confirms homology between lymphoid tissue-resident and dermal XCR1+ DCs in mouse and human and distinguishes them from Langerhans cells
by Carpentier, Sabrina and Vu Manh, Thien-Phong and Chelbi, Rabie and Henri, Sandrine and Malissen, Bernard and Haniffa, Muzlifah and Ginhoux, Florent and Dalod, Marc
Journal of Immunological Methods, ISSN 0022-1759, 05/2016, Volume 432, Issue SI, pp. 35 - 49
Dendritic cells (DC) are mononuclear phagocytes which exhibit a branching (dendritic) morphology and excel at naïve T cell activation. DC encompass several... 
Langerhans cells | Comparative genomics | Skin | XCR1 | Dendritic cells | Bioinformatics | FUNCTIONAL SPECIALIZATION | MACROPHAGES | TOLERANCE | BIOCHEMICAL RESEARCH METHODS | GENE-EXPRESSION PROFILES | MONOCYTES | CD8-ALPHA(+) | IMMUNOLOGY | CD8(+) T-CELLS | MOLECULAR SIGNATURES | Skin - cytology | Receptors, G-Protein-Coupled - metabolism | Species Specificity | Skin - metabolism | Dendritic Cells - immunology | Humans | Databases, Genetic | Gene Expression Profiling | Lymphoid Tissue - immunology | Receptors, G-Protein-Coupled - immunology | Cell Differentiation - genetics | Langerhans Cells - immunology | Transcription, Genetic | Genomics - methods | Receptors, Chemokine - genetics | Dendritic Cells - metabolism | Skin - immunology | Receptors, Chemokine - metabolism | Computational Biology | Gene Expression Regulation | Lymphoid Tissue - metabolism | Genetic Markers | Receptors, Chemokine - immunology | Lymphoid Tissue - cytology | Phenotype | Animals | High-Throughput Nucleotide Sequencing | Mice | Receptors, G-Protein-Coupled - genetics | Langerhans Cells - metabolism | Life Sciences | Immunology | CLN_migDCs, cutaneous lymph node migratory dendritic cells | DMPs, dermal mononuclear phagocytes | MPs, mononuclear phagocytes | Mo, monocytes | DDCs, dermal dendritic cells | LT-DCs, lymphoid tissue-resident dendritic cells | MoDCs, monocyte-derived dendritic cells | PCA, principal component analysis | LCs, Langerhans cells | FDR, false discovery rate | Mac, macrophages | Research Paper | DC, dendritic cells | GSEA, gene set enrichment analysis | NES, normalized enrichment score
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3. Full Text African trypanosomiasis-associated anemia: The contribution of the interplay between parasites and the mononuclear phagocyte system
by Stijlemans, Benoit and De Baetselier, Patrick and Magez, Stefan and Van Ginderachter, Jo A and De Trez, Carl
Frontiers in Immunology, ISSN 1664-3224, 02/2018, Volume 9, p. 218
African trypanosomosis (AT) is a chronically debilitating parasitic disease of medical and economic importance for the development of sub-Saharan Africa. The... 
MPS | IFN-γ | Anemia | Hemodilution | Inflammation | MIF | Erythrophagocytosis | IL-10 | MIGRATION INHIBITORY FACTOR | SLEEPING SICKNESS | IMMUNOLOGY | hemodilution | anemia | MACROPHAGE ACTIVATION | VARIANT SURFACE GLYCOPROTEIN | TUMOR-NECROSIS-FACTOR | NITRIC-OXIDE PRODUCTION | BRUCEI-INFECTED MICE | IFN-gamma | inflammation | erythrophagocytosis | CONGOLENSE INFECTION | T-CELLS | MOLECULAR-MECHANISMS | Mononuclear Phagocyte System - immunology | Anemia - immunology | Anemia - blood | Macrophage Migration-Inhibitory Factors - immunology | Trypanosoma brucei gambiense - pathogenicity | Anemia - parasitology | Galectin 3 - metabolism | Trypanosoma brucei gambiense - immunology | Macrophage Migration-Inhibitory Factors - metabolism | Galectin 3 - immunology | Host-Parasite Interactions - immunology | Trypanosomiasis, African - immunology | Trypanosomiasis, African - parasitology | Animals | Trypanosomiasis, African - blood | Interleukin-10 - metabolism | Mice | Mononuclear Phagocyte System - metabolism | Interleukin-10 - immunology | Disease Models, Animal | Erythropoiesis - immunology | Immune response | Research | African trypanosomiasis
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4. Full Text PEGylation as a strategy for improving nanoparticle-based drug and gene delivery
by Suk, Jung Soo and Xu, Qingguo and Kim, Namho and Hanes, Justin and Ensign, Laura M
Advanced Drug Delivery Reviews, ISSN 0169-409X, 04/2016, Volume 99, Issue Pt A, pp. 28 - 51
Coating the surface of nanoparticles with polyethylene glycol (PEG), or “PEGylation”, is a commonly used approach for improving the efficiency of drug and gene... 
Stealth coatings | Mononuclear phagocyte system (MPS) | Enhanced permeability and retention (EPR) effect | Liposomes | Mucosal delivery | POLYETHYLENE-GLYCOL PEG | COMPACTED DNA NANOPARTICLES | POLYMER-BASED NANOPARTICLE | SOLID LIPID NANOPARTICLES | PLASMA-PROTEIN ADSORPTION | HUMAN CERVICOVAGINAL MUCUS | POLY(ETHYLENE GLYCOL) | ACCELERATED BLOOD CLEARANCE | PHARMACOLOGY & PHARMACY | CYSTIC-FIBROSIS SPUTUM | MUCUS-PENETRATING PARTICLES | Gene Transfer Techniques | Animals | Nanoparticles - chemistry | Humans | Surface Properties | Polyethylene Glycols - chemistry | Nanoparticles - administration & dosage | Polyethylene Glycols - administration & dosage | Drug Delivery Systems | Drugs | Proteins | Drug delivery systems | Polyethylene glycol | Genes | Genetic research | Polyols | Vehicles | Medical colleges | Permeability | Biomedical engineering | mononuclear phagocyte system (MPS) | stealth coatings | liposomes | enhanced permeability and retention (EPR) effect
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5. Full Text Exosomes as therapeutic drug carriers and delivery vehicles across biological membranes: current perspectives and future challenges
by Ha, Dinh and Yang, Ningning and Nadithe, Venkatareddy
Acta Pharmaceutica Sinica B, ISSN 2211-3835, 07/2016, Volume 6, Issue 4, pp. 287 - 296
Exosomes are small intracellular membrane-based vesicles with different compositions that are involved in several biological and pathological processes. The... 
Extracellular vesicles | Drug delivery systems | Nanocarrier | Exosomes | OXIDATIVE STRESS | DENDRITIC CELLS | SHORT INTERFERING RNA | BLOOD-BRAIN-BARRIER | CANCER-THERAPY | BREAST-CANCER | MULTIVESICULAR BODIES | Nariocarrie | PHARMACOLOGY & PHARMACY | Extraecllular vesicles | CELL-DERIVED EXOSOMES | Drug delivery system | SUPEROXIDE-DISMUTASE | PARKINSONS-DISEASE | PEG, polyethylene glycol | MVB, multi-vesicular body biogenesis | PD, Parkinson’s disease | Hsp, heat shock proteins | EGF, epidermal growth factor | PBMC, peripheral blood mononuclear cells | siRNA, small interference RNA | kRAS, Kirsten rat sarcoma | CCK-8, cell counting kit-8 | miRNA, micro RNA | Review | TNF-α, tumor necrosis factor α | CD, cluster of differentiation | ESCRT, endosomal sorting complexes required for transport | IL-6, interleukin-6 | ALIX, ALG-2 interacting protein X | RPE1, retinal pigment epithelial cells 1 | TSG101, tumor susceptibility gene 101 | ROS, reactive oxygen species | DNA, deoxyribonucleic acid | MPS, mononuclear phagocyte system | HEK293, human embryonic kidney cell line 293 | DIL, 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate | ILVs, intraluminal vesicles | mRNA, messenger RNA | RNA, ribonucleic acid | HIV, human immunodeficiency virus | BBB, blood–brain barrier | EGFR, epidermal growth factor receptor | MHC, major histocompatibility complex | LPS, lipopolysaccharides | HMGA2, high-mobility group AT-hook protein | HeLa, Henrietta Lacks cells | VPS4, vacuolar protein sorting-associated protein 4 | EV, extracellular vesicle | MAPK-1, mitogen-activated protein kinase 1 | ATPase, adenosine triphosphatase | EpCAM, epithelial cell adhesion molecule
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6. Full Text IL-34 and CSF-1: similarities and differences
by Nakamichi, Yuko and Udagawa, Nobuyuki and Takahashi, Naoyuki
Journal of Bone and Mineral Metabolism, ISSN 0914-8779, 9/2013, Volume 31, Issue 5, pp. 486 - 495
Colony-stimulating factor-1 (CSF-1) is widely expressed and considered to regulate the development, maintenance, and function of mononuclear phagocyte lineage... 
Medicine & Public Health | Orthopedics | MPS (mononuclear phagocyte system) | Metabolic Diseases | IL-34 | CSF-1 | CSF-1R | Macrophage | MEDICINE, RESEARCH & EXPERIMENTAL | COLLAGEN-INDUCED ARTHRITIS | COLONY-STIMULATING FACTOR | OSTEOPETROTIC OP/OP MICE | PRECURSORS IN-VIVO | MONONUCLEAR PHAGOCYTE SYSTEM | MOUSE BONE-MARROW | LANGERHANS CELLS | HEMATOPOIETIC PROGENITOR CELLS | ENDOCRINOLOGY & METABOLISM | DENDRITIC CELL-DEVELOPMENT | TYROSINE KINASE INHIBITOR | Interleukins - genetics | Animals | Cell Differentiation | Macrophage Colony-Stimulating Factor - metabolism | Mice | Macrophage Colony-Stimulating Factor - genetics | Osteoclasts - cytology | Osteoclasts - metabolism | Interleukins - metabolism | Dendritic cells | Interleukins | Macrophage colony stimulating factor
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7. Full Text Animal models for analysis of immunological responses to nanomaterials: Challenges and considerations
by Zamboni, William C and Szebeni, Janos and Kozlov, Serguei V and Lucas, Andrew T and Piscitelli, Joseph A and Dobrovolskaia, Marina A
Advanced Drug Delivery Reviews, ISSN 0169-409X, 11/2018, Volume 136-137, pp. 82 - 96
Nanotechnology provides many solutions to improve conventional drug delivery and has a unique niche in the areas related to the specific targeting of the... 
Nanoparticles | Allergy | MPS | Animals | Anaphylaxis | Complement | Inflammation | Macrophages | Cytokine storm | PEGYLATED LIPOSOMAL DOXORUBICIN | COMPLEMENT ACTIVATION | DRUG WITHDRAWALS | MONONUCLEAR PHAGOCYTE SYSTEM | TOXICOLOGICAL PROPERTIES | HUMANIZED MOUSE MODELS | ACCELERATED BLOOD CLEARANCE | CKD-602 S-CKD602 | PHARMACOLOGY & PHARMACY | PULMONARY INTRAVASCULAR MACROPHAGES | PHOSPHOROTHIOATE OLIGONUCLEOTIDE | Drugs | Animal experimentation | Medical research | Drug delivery systems | School facilities | Immunotherapy | Medicine, Experimental | Nanotechnology | Vehicles | Education parks
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8. Full Text ELEVATED LEVELS OF PLASMA TNF-alpha ARE ASSOCIATED WITH MICROVASCULAR ENDOTHELIAL DYSFUNCTION IN PATIENTS WITH SEPSIS THROUGH ACTIVATING THE NF-B-k AND P38 MITOGEN-ACTIVATED PROTEIN KINASE IN ENDOTHELIAL CELLS
by Liang, YJ and Li, X and Zhang, XJ and Li, ZL and Wang, L and Sun, YN and Liu, ZY and Ma, XC
SHOCK, ISSN 1073-2322, 04/2014, Volume 41, Issue 4, pp. 275 - 281
Inflammatory responses can induce microvascular and endothelial dysfunction, which is associated with the development of sepsis. This study is aimed at... 
SURGERY | vWF | HCs healthy controls | VASCULAR DYSFUNCTION | NF-B | KAPPA-B | TNF | MAPK mitogen activated protein kinase | NITRIC-OXIDE | LIPOPOLYSACCHARIDE | PERIPHERAL VASCULAR DISEASE | ORGAN DYSFUNCTION | STRESS | HEMATOLOGY | APACHE Acute Physiology and Chronic Health Evaluation | CRITICAL CARE MEDICINE | BARRIER DYSFUNCTION | NP normal plasma | SP septic plasma | SIRS systemic inflammatory response syndrome | p38 MAPK | vWF von Willebrand factor | HUVECs human umbilical vein endothelial cells | MPs mononuclear phagocytes | TNF tumor necrosis factor | NF-B nuclear factor-B | ACST acute cholangitis of severe type | INFLAMMATION | DISEASE | LPS lipopolysaccharide | vascular endothelial cells | SAP severe acute pancreatitis | EXPRESSION | sepsis | TF tissue factor
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9. Full Text SOD1 nanozyme with reduced toxicity and MPS accumulation
by Jiang, Yuhang and Arounleut, Phonepasong and Rheiner, Steven and Bae, Younsoo and Kabanov, Alexander V and Milligan, Carol and Manickam, Devika S
Journal of Controlled Release, ISSN 0168-3659, 06/2016, Volume 231, pp. 38 - 49
We previously developed a “cage”-like nano-formulation (nanozyme) for copper/Zinc superoxide dismutase (SOD1) by polyion condensation with a conventional block... 
MPS | Stroke | Mouse | Toxicity | Protein delivery | ALS | Superoxide dismutase | PEG-PLL | Antioxidant | PEG-PAsp(DET) | LINKED ANTIOXIDANT NANOZYMES | OXIDATIVE STRESS | SOD1(G93A) MOUSE MODEL | POLYPLEX NANOMICELLES | AMYOTROPHIC-LATERAL-SCLEROSIS | CHEMISTRY, MULTIDISCIPLINARY | TIME UPTAKE DATA | IN-VIVO | BRAIN TRANSFER CONSTANTS | PHARMACOLOGY & PHARMACY | GENE-TRANSFER | ENTRAPPED SUPEROXIDE-DISMUTASE | Neurons - pathology | Superoxide Dismutase-1 - toxicity | Antioxidants - chemistry | Nanoparticles - chemistry | Superoxide Dismutase-1 - pharmacology | Humans | Microvessels - pathology | Mononuclear Phagocyte System - pathology | Male | Polyethylene Glycols - chemistry | Amyotrophic Lateral Sclerosis - drug therapy | Stroke - pathology | Tissue Distribution | Brain - blood supply | Female | Neurons - drug effects | Mice, Inbred C57BL | Microvessels - drug effects | Mice, Transgenic | Stroke - drug therapy | Antioxidants - pharmacology | Superoxide Dismutase-1 - chemistry | Antioxidants - toxicity | Brain - drug effects | Amyotrophic Lateral Sclerosis - pathology | Animals | Superoxide Dismutase-1 - genetics | Brain - pathology | Mononuclear Phagocyte System - drug effects | Mutation | Proteins - chemistry | Stroke (Disease) | Ethylene glycol | Lysine | Analysis | Aspartate | Superoxide | Block copolymers | Drugs | Medical colleges | Drug delivery systems | Liver | Drugstores | Neurophysiology | Vehicles | Pharmacy | Nanotechnology | Index Medicus
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