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Annual Review of Biochemistry, ISSN 0066-4154, 6/2018, Volume 87, Issue 1, pp. 263 - 294
Genomic instability in disease and its fidelity in health depend on the DNA damage response (DDR), regulated in part from the complex of meiotic recombination... 
coiled-coil domain | nuclease | ATPase | BRCT domains | BRCA1 C-terminal domains | CtIP tetramerization | FHA domain | forkhead-associated domain | CtBP-interacting protein tetramerization | STRAND BREAK REPAIR | RAD50 ZINC-HOOK | BIOCHEMISTRY & MOLECULAR BIOLOGY | X-RAY-SCATTERING | LATE GENE-EXPRESSION | PATHWAY CHOICE | PROTEIN-A RPA | END RESECTION | MRN COMPLEX | IONIZING-RADIATION | MRE11 NUCLEASE | Signal Transduction | Humans | DNA Repair Enzymes - genetics | Models, Molecular | DNA Replication | MRE11 Homologue Protein - chemistry | DNA-Binding Proteins - genetics | Immunity, Innate | DNA-Binding Proteins - chemistry | DNA-Binding Proteins - metabolism | Models, Biological | DNA Repair | DNA Repair Enzymes - metabolism | Telomere - metabolism | DNA Damage | MRE11 Homologue Protein - metabolism | DNA Repair Enzymes - chemistry | MRE11 Homologue Protein - genetics | Biological research | DNA replication | RecA proteins | Physiological aspects | Biochemical genetics | Genetic aspects | Research | DNA repair | Biology, Experimental | Recombination | DNA damage | Nijmegen breakage syndrome | Homology | Kinases | Replication forks | Genomic instability | Proteins | MRE11 protein | Damage | Deoxyribonucleic acid--DNA | Stability | Conductors | Ribonucleases | Replication protein A | Meiosis | Protein A | DNA biosynthesis | Telomeres | Scaffolding | Breakage | Replication | Genetic recombination | Adenosine triphosphatase | Cancer | Nijmegen breakage syndrome protein 1
Journal Article
Nature Structural and Molecular Biology, ISSN 1545-9993, 01/2012, Volume 19, Issue 1, pp. 17 - 25
In higher eukaryotes, the dynamics of replisome components during fork collapse and restart are poorly understood. Here we have reconstituted replication fork... 
BUDDING YEAST | DORMANT ORIGINS | BIOCHEMISTRY & MOLECULAR BIOLOGY | POLYMERASE ALPHA | DAMAGE TOLERANCE | CELL BIOLOGY | S PHASE CHECKPOINT | REPAIR | BIOPHYSICS | RESTART | HOMOLOGOUS RECOMBINATION | CHROMOSOMAL DNA-REPLICATION | BREAK-INDUCED REPLICATION | Chromatin - metabolism | Xenopus Proteins - genetics | Male | Multiprotein Complexes - genetics | Minichromosome Maintenance Complex Component 2 | DNA-Binding Proteins - metabolism | MRE11 Homologue Protein | Multiprotein Complexes - metabolism | Proliferating Cell Nuclear Antigen - genetics | Chromatin Immunoprecipitation | Electrophoresis, Agar Gel | Cell Cycle Proteins - genetics | Female | DNA, Single-Stranded | DNA Helicases - genetics | Rad51 Recombinase - metabolism | Recombinant Proteins - metabolism | Rad51 Recombinase - genetics | Oocytes - metabolism | Xenopus laevis | Cell Cycle Proteins - metabolism | DNA Replication | DNA-Binding Proteins - genetics | Comet Assay | Blotting, Western | Carrier Proteins - genetics | DNA Helicases - metabolism | Animals | Carrier Proteins - metabolism | Protein Binding | Xenopus Proteins - metabolism | DNA Damage | Mutation | Proliferating Cell Nuclear Antigen - metabolism | Gene mutations | DNA | Physiological aspects | Research | Structure | Health aspects | Helicases | Enzymes | Eukaryotes | Molecular biology | Genomics | Deoxyribonucleic acid--DNA | Index Medicus
Journal Article
Journal Article
The EMBO Journal, ISSN 0261-4189, 04/2019, Volume 38, Issue 7, pp. e101005 - n/a
Journal Article
Molecular Oncology, ISSN 1574-7891, 2008, Volume 2, Issue 4, pp. 296 - 316
Journal Article