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science & technology (48) 48
life sciences & biomedicine (45) 45
humans (38) 38
animals (28) 28
multidrug resistance-associated proteins - metabolism (21) 21
mrp2 (20) 20
proteins (19) 19
multidrug resistance-associated proteins - genetics (18) 18
pharmacology & pharmacy (18) 18
biochemistry & molecular biology (16) 16
drug resistance in microorganisms (14) 14
adenosine triphosphate - metabolism (13) 13
biological and medical sciences (13) 13
medical sciences (12) 12
research (12) 12
atp-binding cassette transporters - metabolism (11) 11
cell line (11) 11
male (11) 11
abcc2 (9) 9
biological transport (9) 9
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liver - metabolism (9) 9
pharmacology. drug treatments (8) 8
atp binding cassette transporter, subfamily b, member 1 - metabolism (7) 7
atp-binding cassette transporters - genetics (7) 7
drug resistance, multiple (7) 7
mice (7) 7
oncology (7) 7
atp binding cassette subfamily b member 11 (6) 6
blotting, western (6) 6
glutathione - metabolism (6) 6
membrane transport proteins - metabolism (6) 6
p-glycoprotein (6) 6
rats (6) 6
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abc transporters (5) 5
adult (5) 5
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bile acids and salts - metabolism (5) 5
binding sites (5) 5
genetic aspects (5) 5
leukotriene c4 - metabolism (5) 5
medical research (5) 5
middle aged (5) 5
multidrug resistance-associated proteins (5) 5
multidrug resistance-associated proteins - chemistry (5) 5
pharmacokinetics (5) 5
toxicology (5) 5
adenosine triphosphatases - metabolism (4) 4
aged (4) 4
amino acid sequence (4) 4
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atp (4) 4
atp-binding cassette transporters - antagonists & inhibitors (4) 4
atp-binding cassette transporters - physiology (4) 4
atp-binding cassette, sub-family b, member 1 - metabolism (4) 4
biochemistry (4) 4
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membrane transport proteins (4) 4
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models, molecular (4) 4
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multidrug resistance (4) 4
multidrug resistance-associated proteins - antagonists & inhibitors (4) 4
protein binding (4) 4
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antineoplastic agents (3) 3
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atp binding cassette transporter, sub-family g, member 2 (3) 3
atp binding cassette transporter, subfamily b - metabolism (3) 3
bile acids (3) 3
biological transport - physiology (3) 3
biological transport, active (3) 3
biophysics (3) 3
cancer research (3) 3
cell membrane - metabolism (3) 3
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drug interactions (3) 3
enzyme inhibitors - pharmacology (3) 3
estradiol - analogs & derivatives (3) 3
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gene expression (3) 3
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1. Full Text The multidrug resistance-associated protein (MRP/ABCC) subfamily of ATP-binding cassette transporters in plants
by Klein, Markus and Burla, Bo and Martinoia, Enrico
FEBS letters, ISSN 0014-5793, 2006, Volume 580, Issue 4, pp. 1112 - 1122
Tonoplast | Guard cell regulation | Transport | Vacuole | Detoxification | Plasma membrane | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Gene Expression | Multigene Family | Plants - metabolism | Species Specificity | Genes, Plant | Multidrug Resistance-Associated Proteins - genetics | Multidrug Resistance-Associated Proteins - metabolism | Metabolites | Analysis | Plant genetics | Index Medicus
Journal Article
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2. Full Text Could polymorphisms in ATP-binding cassette C3/multidrug resistance associated protein 3 ( ABCC3/MRP3 ) modify colorectal cancer risk?
by Campa, Daniele and Vodicka, Pavel and Pardini, Barbara and Novotny, Jan and Försti, Asta and Hemminki, Kari and Barale, Roberto and Canzian, Federico
European journal of cancer (1990), ISSN 0959-8049, 2008, Volume 44, Issue 6, pp. 854 - 857
Hematology, Oncology and Palliative Medicine | ABCC3 | Polymorphisms | Susceptibility | Transporter | Colorectal cancer | Life Sciences & Biomedicine | Oncology | Science & Technology | Biological and medical sciences | Medical sciences | Pharmacology. Drug treatments | Tumors | Colorectal Neoplasms - genetics | Humans | Middle Aged | Risk Factors | Genotype | Male | Case-Control Studies | Aged, 80 and over | Adult | Female | Multidrug Resistance-Associated Proteins - genetics | Polymorphism, Genetic - genetics | Aged | Drug resistance in microorganisms | Genetic aspects | Health aspects | Risk factors | Index Medicus
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3. Full Text Structural model of ATP-binding proteins associated with cystic fibrosis, multidrug resistance and bacterial transport
by Hyde, Stephen C and Hyde, Stephen C and Emsley, Paul and Hartshorn, Michael J and Mimmack, Michael M and Mimmack, Michael M and Gileadi, Uzi and Gileadi, Uzi and Pearce, Stephen R and Pearce, Stephen R and Gallagher, Maurice P and Gallagher, Maurice P and Gill, Deborah R and Gill, Deborah R and Hubbard, Roderick E and Higgins, Christopher F and Higgins, Christopher F
Nature (London), ISSN 0028-0836, 1990, Volume 346, Issue 6282, pp. 362 - 365
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Proteins | Binding and carrier proteins | Biological and medical sciences | Analytical, structural and metabolic biochemistry | Amino Acid Sequence | Membrane Glycoproteins - metabolism | Salmonella typhimurium - genetics | Cystic Fibrosis - metabolism | Humans | Models, Molecular | Molecular Sequence Data | Neoplasm Proteins - metabolism | Sequence Homology, Nucleic Acid | ATP-Binding Cassette, Sub-Family B, Member 1 | Salmonella typhimurium - metabolism | Carrier Proteins - genetics | Drug Resistance - genetics | Animals | Carrier Proteins - metabolism | Escherichia coli - genetics | Adenosine Triphosphate - metabolism | Cystic Fibrosis - genetics | Escherichia coli - metabolism | Protein Conformation | Drosophila - metabolism | Drosophila - genetics | Causes of | Cystic fibrosis | Ion channels | Genetic aspects | Research | Mutation (Biology) | Medical research | Genetics | Yeast | A-factor | Prokaryotes | Tertiary structure | Multidrug resistance | Chloroquine | Amino acids | Glycoproteins | Kinases | Carbon | Adenylate kinase | Fibrosis | Experimentation | Transport | P-Glycoprotein | ATP | Protein structure | Tumors | Cassettes | ATP-binding protein | cystic fibrosis | Index Medicus
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4. Full Text ATP Binding to the First Nucleotide Binding Domain of Multidrug Resistance-associated Protein Plays a Regulatory Role at Low Nucleotide Concentration, whereas ATP Hydrolysis at the Second Plays a Dominant Role in ATP-dependent Leukotriene C4 Transport
by Runying Yang and Liying Cui and Yue-xian Hou and John R. Riordan and Xiu-bao Chang
The Journal of biological chemistry, ISSN 0021-9258, 08/2003, Volume 278, Issue 33, pp. 30764 - 30771
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Protein Structure, Tertiary | Amino Acid Sequence | Cell Line | Cricetinae | Humans | Enzyme Inhibitors - pharmacology | Kidney - cytology | Cysteine - genetics | Hydrolysis | Animals | Mutagenesis | Adenosine Triphosphate - metabolism | Ethylmaleimide - pharmacology | Biological Transport - physiology | Leukotriene C4 - metabolism | Binding Sites | Amino Acid Substitution | Index Medicus
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5. Full Text ATP-dependent Transport of Bile Salts by Rat Multidrug Resistance-associated Protein 3 (Mrp3)
by Tomoko Hirohashi and Hiroshi Suzuki and Hajime Takikawa and Yuichi Sugiyama
The Journal of biological chemistry, ISSN 0021-9258, 01/2000, Volume 275, Issue 4, pp. 2905 - 2910
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Drug Resistance, Multiple | Humans | Rats | Bile Acids and Salts - metabolism | Tritium | Osmosis | ATP-Binding Cassette Transporters - physiology | LLC-PK1 Cells | Animals | Biological Transport | Swine | Adenosine Triphosphate - metabolism | Cell Membrane - metabolism | Kinetics | Multidrug Resistance-Associated Proteins | Index Medicus
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6. Full Text Interaction between the Bound Mg·ATP and the Walker A Serine Residue in NBD2 of Multidrug Resistance-Associated Protein MRP1 Plays a Crucial Role for the ATP-Dependent Leukotriene C4 Transport
by Yang, Runying and Scavetta, Robert and Chang, Xiu-bao
Biochemistry (Easton), ISSN 0006-2960, 08/2008, Volume 47, Issue 32, pp. 8456 - 8464
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7. Full Text Evaluation of the binding of the tricyclic isoxazole photoaffinity label LY475776 to multidrug resistance associated protein 1 (MRP1) orthologs and several ATP-binding cassette (ABC) drug transporters
by Dantzig, Anne H and Shepard, Robert L and Pratt, Susan E and Tabas, Linda B and Lander, Peter A and Ma, Liandong and Paul, Donald C and Williams, Daniel C and Peng, Sheng-Bin and Slapak, Christopher A and Godinot, Nathalie and Perry, William L
Biochemical pharmacology, ISSN 0006-2952, 2004, Volume 67, Issue 6, pp. 1111 - 1121
P-glycoprotein | MRP1 ortholog | Photoaffinity label | ABC transporter | Breast cancer resistance protein | LY475776 | BCRP | ABC | Leukotriene C | DOX | Doxorubicin | Fetal bovine serum | Geneticin | G418 | The concentration that gives 50% of the maximal response | FBS | ATP-binding cassette | LTC | GSH | Glutathione | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Biological and medical sciences | Pharmacology. Drug treatments | Medical sciences | Amino Acid Sequence | Photoaffinity Labels | Species Specificity | Drug Resistance, Multiple | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Molecular Sequence Data | Cell Division - drug effects | Isoxazoles - pharmacology | Sequence Homology, Amino Acid | Animals | ATP-Binding Cassette Transporters - genetics | ATP-Binding Cassette Transporters - metabolism | Multidrug Resistance-Associated Proteins - genetics | Mice | Azides - pharmacology | HeLa Cells | Tumor Cells, Cultured | Multidrug Resistance-Associated Proteins - metabolism | Index Medicus
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8. Full Text ATP binding, not hydrolysis, at the first nucleotide-binding domain of multidrug resistance-associated protein MRP1 enhances ADP·Vi trapping at the second domain
by Hou, Yue-xian and Riordan, John R and Chang, Xiu-bao
The Journal of biological chemistry, ISSN 0021-9258, 02/2003, Volume 278, Issue 6, pp. 3599 - 3605
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology
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9. Full Text Study Findings from Medical University of Vienna Broaden Understanding of ATP-Dependent Organic Anion Transporters [In vitro function and in situ localization of Multidrug Resistance-associated Protein (MRP)1 (ABCC1) suggest a protective role ...]
09/2020
Health aspects | Adenosine triphosphatase | Methylmercury | Protein binding
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10. Full Text Zhengzhou University Reports Findings in ATP-Dependent Organic Anion Transporters [The Efflux Mechanism of Fraxetin-o-glucuronides In Ugt1a9-transfected Hela Cells: Identification of Multidrug Resistance-associated Proteins 3 and 4 (Mrp3/4) As ...]
Obesity, fitness, & wellness week, ISSN 1531-6386, 06/2019, p. 8551
Type 2 diabetes | Drug resistance in microorganisms | Physical fitness | Dietary supplements | Physiological aspects | Research | Diabetes therapy
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11. Full Text Elevated hepatic multidrug resistance‐associated protein 3/ATP‐binding cassette subfamily C 3 expression in human obstructive cholestasis is mediated through tumor necrosis factor alpha and c‐Jun NH2‐terminal kinase/stress‐activated protein kinase–signaling pathway
by Chai, Jin and He, Yu and Cai, Shi‐Ying and Jiang, Zhongyong and Wang, Huaizhi and Li, Qiong and Chen, Lei and Peng, Zhihong and He, Xiaochong and Wu, Xiaoping and Xiao, Tianli and Wang, Rongquan and Boyer, James L and Chen, Wensheng
Hepatology (Baltimore, Md.), ISSN 0270-9139, 05/2012, Volume 55, Issue 5, pp. 1485 - 1494
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Gastroenterology. Liver. Pancreas. Abdomen | Biological and medical sciences | Medical sciences | Liver. Biliary tract. Portal circulation. Exocrine pancreas | Other diseases. Semiology | Tumor Necrosis Factor-alpha - metabolism | Cholestasis - genetics | Up-Regulation | Cholestasis - metabolism | Humans | Middle Aged | Tumor Necrosis Factor-alpha - blood | Real-Time Polymerase Chain Reaction - methods | JNK Mitogen-Activated Protein Kinases - metabolism | Male | Sp1 Transcription Factor - metabolism | RNA, Messenger - metabolism | Case-Control Studies | Sensitivity and Specificity | Adult | Female | Multidrug Resistance-Associated Proteins - genetics | JNK Mitogen-Activated Protein Kinases - genetics | Signal Transduction | Tissue Culture Techniques | Tumor Cells, Cultured - drug effects | Gene Expression Regulation | Blotting, Western | Disease Progression | Cholestasis - pathology | Fluorescent Antibody Technique | Biopsy, Needle | Multidrug Resistance-Associated Proteins - metabolism | Tumor necrosis factor-TNF | Kinases | Rodents | Bile | Index Medicus
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12. Full Text The human multidrug-resistance-associated protein MRP1 mediates ATP-dependent transport of unconjugated bilirubin
by Rigato, Igino and Pascolo, Lorella and Fernetti, Cristina and Ostrow, J. Donald and Tiribelli, Claudio
Biochemical journal, ISSN 0264-6021, 10/2004, Volume 383, Issue 2, pp. 335 - 341
Cytotoxicity | ATP-binding-cassette protein (ABC) protein | Transport | Unconjugated bilirubin | Multidrug-resistance-associated protein 1 (MRP1) | Glutathione | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Cytoplasmic Vesicles - drug effects | Cell Line | Bilirubin - metabolism | Glutathione - metabolism | Humans | Bilirubin - pharmacology | Animals | Adenosine Triphosphate - metabolism | Cytoplasmic Vesicles - metabolism | Dogs | Biological Transport - drug effects | Kinetics | Leukotriene C4 - metabolism | Multidrug Resistance-Associated Proteins - metabolism | Index Medicus | multidrug-resistance-associated protein 1 (MRP1) | unconjugated bilirubin | glutathione | Mrp | MRP1, multidrug-resistance-associated protein 1 | transport | MDCKII cells, Madin–Darby canine kidney II cells | HSA, human serum albumin | CNS, central nervous system | UCB, unconjugated bilirubin | LTC4, leukotriene C4 | cytotoxicity | AMP-PCP, adenosine 5′-[β,γ-methylene]triphosphate (‘pp[β,γ-CH2]pA’)
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