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06/2014
To obtain a cell source for cartilage tissue engineering primary cells are passaged on polystyrene dishes to increase cell number however, this stiff... 
Cartilage | MRTF | 0541 | Actin | dedifferentiation | Tissue Engineering
Dissertation
Experimental Cell Research, ISSN 0014-4827, 07/2019, pp. 111504 - 111504
Journal Article
Journal Article
Cancer Cell, ISSN 1535-6108, 07/2019, Volume 36, Issue 1, pp. 68 - 83.e9
P29 is the third most commonly mutated codon in human cutaneous melanoma, after V600 and Q61. Here, we study the role of RAC1 in melanoma development and... 
MRTF | SRF | NF1 | PTEN | melanoma | BRAF | RAC1 | EMT | p53
Journal Article
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 4/2017, Volume 27, Issue 8, pp. 1744 - 1749
We recently reported the development of a novel inhibitor of Rho-mediated gene transcription ( 1 , CCG-203971) that is efficacious in multiple animal models of... 
Rho | fibrosis | MRTF | Scleroderma | myofibroblast | antifibrotic
Journal Article
The EMBO Journal, ISSN 0261-4189, 08/2019, Volume 38, Issue 16, pp. e101168 - n/a
Nuclear actin participates in many essential cellular processes including gene transcription, chromatin remodelling and mRNA processing. Actin shuttles into... 
nuclear envelope | exportin‐6 | MRTF | RASSF | nuclear actin | exportin-6 | MRTF-A | RASSF1A | Transcription factors | mRNA processing | Gene regulation | Trafficking | Kinases | Adhesion | Nuclear transport | Exports | Chromatin remodeling | Cell adhesion & migration | Receptors | Depletion | Actin | Cell adhesion | Serum response factor | Nuclei (cytology) | Transport | Profilin | Tumors | Guanosinetriphosphatase | Cancer
Journal Article
JOURNAL OF CELL SCIENCE, ISSN 0021-9533, 05/2018, Volume 131, Issue 10, pp. jcs212886 - jcs212886
Journal Article
Molecular & Cellular Oncology, ISSN 2372-3556, 09/2019, Volume 6, Issue 5, pp. 1 - 3
Nuclear actin is exported from the nucleus via the Exportin-6 (XPO6)/RAN GTPase complex. We recently identified that RASSF1A and the hippo pathway kinase... 
Exportin-6 | cancer | MRTF-A | RASSF1A | Nuclear actin
Journal Article
The EMBO Journal, ISSN 0261-4189, 06/2018, Volume 37, Issue 12, pp. e98133 - n/a
Journal Article
Zhongguo fei ai za zhi = Chinese journal of lung cancer, 02/2019, Volume 22, Issue 2, pp. 82 - 89
Journal Article
Advanced Science Letters, ISSN 1936-6612, 07/2013, Volume 19, Issue 7, pp. 1969 - 1973
Journal Article
Canadian Journal of Physiology and Pharmacology, ISSN 0008-4212, 2017, Volume 95, Issue 10, pp. 1263 - 1270
The etiology of cardiac fibrogenesis is quite diverse, but a common feature is the presence of activated fibroblasts. Experimental evidence suggests that a... 
diabète | ATF-3 | fibrose cardiaque | MRTF-A | cardiac fibrosis | TEndM | diabetes | EndMT
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 09/2017, Volume 37, Issue 9, pp. 1674 - 1682
Journal Article
Frontiers in immunology, ISSN 1664-3224, 2019, Volume 10, p. 1138
β2-integrins are essential for immune system function because they mediate immune cell adhesion and signaling. Consequently, a loss of β -integrin expression... 
MKL-1 | dendritic cells | LAD-III | adhesion | MRTF-A | SRF
Journal Article