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science & technology (119) 119
life sciences & biomedicine (117) 117
mrtf-a (84) 84
animals (72) 72
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transcription (20) 20
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hek293 cells (7) 7
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1. Full Text Myocardin-related transcription factors are required for cardiac development and function
by Mokalled, Mayssa H and Carroll, Kelli J and Cenik, Bercin K and Chen, Beibei and Liu, Ning and Olson, Eric N and Bassel-Duby, Rhonda
Developmental biology, ISSN 0012-1606, 10/2015, Volume 406, Issue 2, pp. 109 - 116
Cardiac morphogenesis | MRTF-A/MKL1 | Heart function | Cytoskeletal dynamics | Sarcomere arrangement | MRTF-B/MKL2 | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Microscopy, Electron, Transmission | Echocardiography | Sarcomeres - metabolism | Serum Response Factor - metabolism | Heart - embryology | Heart - physiology | Transcription Factors - deficiency | Molecular Sequence Data | Gene Regulatory Networks - physiology | Mice, Knockout | Transcription Factors - metabolism | Animals | Sequence Analysis, RNA | Trans-Activators - deficiency | Histological Techniques | Base Sequence | Trans-Activators - metabolism | Cytoskeleton - physiology | Mice | Sarcomeres - physiology | Real-Time Polymerase Chain Reaction | Morphogenesis - physiology | Heart failure | DNA binding proteins | Molecular biology | Developmental biology | Analysis | Index Medicus | MKL2 | cytoskeletal dynamics | MRTF-B | MRTF-A | heart function | cardiac morphogenesis | MKL1 | sarcomere arrangement
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2. Full Text p75 neurotrophin receptor regulates NGF-induced myofibroblast differentiation and collagen synthesis through MRTF-A
by Liu, Zhenxing and Cao, Yongqian and Liu, Guijun and Yin, Siyuan and Ma, Jiaxu and Liu, Jian and Zhang, Min and Wang, Yibing
Experimental cell research, ISSN 0014-4827, 10/2019, Volume 383, Issue 1, pp. 111504 - 111504
p75NTR | MRTF-A | NGF | Differentiation | Myofibroblast | Index Medicus
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3. Full Text RAC1P29S Induces a Mesenchymal Phenotypic Switch via Serum Response Factor to Promote Melanoma Development and Therapy Resistance
by Lionarons, Daniël A and Hancock, David C and Rana, Sareena and East, Philip and Moore, Christopher and Murillo, Miguel M and Carvalho, Joana and Spencer-Dene, Bradley and Herbert, Eleanor and Stamp, Gordon and Damry, Djamil and Calado, Dinis P and Rosewell, Ian and Fritsch, Ralph and Neubig, Richard R and Molina-Arcas, Miriam and Downward, Julian
Cancer cell, ISSN 1535-6108, 07/2019, Volume 36, Issue 1, pp. 68 - 83.e9
MRTF | SRF | NF1 | PTEN | melanoma | BRAF | RAC1 | EMT | p53 | Index Medicus
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4. Full Text Interplay of cell–cell contacts and RhoA/MRTF‐A signaling regulates cardiomyocyte identity
by Dorn, Tatjana and Kornherr, Jessica and Parrotta, Elvira I and Zawada, Dorota and Ayetey, Harold and Santamaria, Gianluca and Iop, Laura and Mastantuono, Elisa and Sinnecker, Daniel and Goedel, Alexander and Dirschinger, Ralf J and My, Ilaria and Laue, Svenja and Bozoglu, Tarik and Baarlink, Christian and Ziegler, Tilman and Graf, Elisabeth and Hinkel, Rabea and Cuda, Giovanni and Kääb, Stefan and Grace, Andrew A and Grosse, Robert and Kupatt, Christian and Meitinger, Thomas and Smith, Austin G and Laugwitz, Karl‐Ludwig and Moretti, Alessandra
The EMBO journal, ISSN 0261-4189, 06/2018, Volume 37, Issue 12, p. n/a
RhoA/ROCK signaling | MRTF/SRF | lineage conversion | cardiac fat | cardiac progenitors | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Heart | Stability | Transcription | Cardiac muscle | Muscles | Homeostasis | Cell junctions | RhoA protein | Cardiomyocytes | Adipocytes | Remodeling | Embryos | Molecular chains | Signaling | Cell fate | Islet-1 protein | Actin | Cytoskeleton | Rocks | Mutation | Gene mapping | Localization | Heart diseases | Adipogenesis | Index Medicus | Stem Cells | MRTF | SRF | Cell Adhesion, Polarity & Cytoskeleton | Development & Differentiation | RhoA | ROCK signaling
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5. Full Text Nuclear transport of the serum response factor coactivator MRTF-A is downregulated at tensional homeostasis
by Khaw, Peng T and McGee, Karen M and Bailly, Maryse and Vartiainen, Maria K and Treisman, Richard
EMBO reports, ISSN 1469-221X, 09/2011, Volume 12, Issue 9, pp. 963 - 970
actin dynamics | tissue tension | cofilin | MRTF‐A/MAL–SRF pathway | MRTF-A/MAL-SRF pathway | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Serum Response Factor - genetics | Cell Line | NIH 3T3 Cells | Signal Transduction | Serum Response Factor - metabolism | Down-Regulation | Actins - metabolism | Stress, Physiological | Homeostasis | Actins - genetics | DNA-Binding Proteins - metabolism | Transcription Factors - metabolism | Animals | Cofilin 1 - metabolism | Trans-Activators - genetics | Trans-Activators - metabolism | Mice | Active Transport, Cell Nucleus | Cofilin 1 - biosynthesis | Gene expression | Index Medicus | MAL–SRF pathway | Scientific Reports | MRTF-A
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6. Full Text RASSF1A is required for the maintenance of nuclear actin levels
by Chatzifrangkeskou, Maria and Pefani, Dafni‐Eleftheria and Eyres, Michael and Vendrell, Iolanda and Fischer, Roman and Pankova, Daniela and O'Neill, Eric
The EMBO journal, ISSN 0261-4189, 08/2019, Volume 38, Issue 16, pp. e101168 - n/a
nuclear envelope | exportin‐6 | MRTF‐A | RASSF1A | nuclear actin | exportin-6 | MRTF-A | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Serum Response Factor - genetics | Tumor Suppressor Proteins - metabolism | Prognosis | Liver Neoplasms - genetics | Serum Response Factor - metabolism | Down-Regulation | Humans | Actins - metabolism | Gene Expression Regulation, Neoplastic | Cytoplasm - metabolism | Breast Neoplasms - metabolism | Nuclear Envelope - metabolism | DNA Methylation | Breast Neoplasms - genetics | Karyopherins - metabolism | Biological Transport | Tumor Suppressor Proteins - genetics | HEK293 Cells | Liver Neoplasms - metabolism | Cell Line, Tumor | Female | Trans-Activators - metabolism | HeLa Cells | Transcription factors | mRNA processing | Gene regulation | Guanosine triphosphatases | Kinases | Adhesion | Nuclear transport | Exports | Chromatin remodeling | Cell adhesion & migration | Receptors | Depletion | Actin | Cell adhesion | Serum response factor | Nuclei (cytology) | Transport | Profilin | Tumors | Cancer | Index Medicus | Signal Transduction | Cell Adhesion, Polarity & Cytoskeleton | Membrane & Intracellular Transport
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7. Full Text CDC42 regulates the expression of superficial zone molecules in part through the actin cytoskeleton and myocardin‐related transcription factor‐A
by Delve, Elizabeth and Parreno, Justin and Co, Vivian and Wu, Po‐Han and Chong, Jasmine and Di Scipio, Matteo and Kandel, Rita A
Journal of orthopaedic research, ISSN 0736-0266, 09/2018, Volume 36, Issue 9, pp. 2421 - 2430
CDC42 | actin cytoskeleton | proteoglycan 4 | MRTF‐A | superficial zone chondrocytes | MRTF-A | Life Sciences & Biomedicine | Orthopedics | Science & Technology | Actin Cytoskeleton - metabolism | Signal Transduction | Gene Silencing | Osteoarthritis - metabolism | Proteoglycans - metabolism | Nuclear Proteins - metabolism | cdc42 GTP-Binding Protein - metabolism | Inflammation | Cytochalasin D - pharmacology | Tenascin - metabolism | Transcription Factors - metabolism | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Animals | Cartilage, Articular - metabolism | Cattle | Trans-Activators - metabolism | Thiazolidines - pharmacology | Chondrocytes - metabolism | Actin | Index Medicus
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8. Full Text Targeting effector pathways in RAC1P29S-driven malignant melanoma
by Uribe-Alvarez, Cristina and Guerrero-Rodríguez, Sandra Lucía and Rhodes, Jennifer and Cannon, Alexa and Chernoff, Jonathan and Araiza-Olivera, Daniela
Small GTPases, ISSN 2154-1248, 02/2020, pp. 1 - 9
Index Medicus
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9. Full Text BRG1 (Brahma-Related Gene 1) Promotes Endothelial Mrtf Transcription to Establish Embryonic Capillary Integrity
by Menendez, Matthew T and Ong, E-Ching and Shepherd, Brian T and Muthukumar, Vijay and Silasi-Mansat, Robert and Lupu, Florea and Griffin, Courtney T
Arteriosclerosis, thrombosis, and vascular biology, ISSN 1079-5642, 09/2017, Volume 37, Issue 9, pp. 1674 - 1682
MRTF-B | serum response factor | MRTF-A | BRG1 | SWI/SNF | Peripheral Vascular Disease | Life Sciences & Biomedicine | Hematology | Cardiovascular System & Cardiology | Science & Technology | Serum Response Factor - genetics | Epigenesis, Genetic | Transcription Factors - deficiency | Antigens, CD - genetics | Morphogenesis | Transfection | RNA Interference | Gene Expression Regulation, Developmental | Nuclear Proteins - deficiency | Trans-Activators - genetics | Transcription, Genetic | Cadherins - genetics | Nuclear Proteins - genetics | Binding Sites | Capillaries - metabolism | DNA Helicases - genetics | Cell Line | Promoter Regions, Genetic | Signal Transduction | Endothelial Cells - metabolism | Serum Response Factor - metabolism | Genotype | Nuclear Proteins - metabolism | DNA Helicases - deficiency | Transcription Factors - genetics | Gestational Age | Mice, Knockout | Transcription Factors - metabolism | DNA Helicases - metabolism | Phenotype | Animals | Trans-Activators - metabolism | Capillaries - embryology | Integrases - genetics | Neovascularization, Physiologic | Index Medicus
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10. Full Text Rho-actin signaling to the MRTF coactivators dominates the immediate transcriptional response to serum in fibroblasts
by Esnault, Cyril and Stewart, Aengus and Gualdrini, Francesco and East, Phil and Horswell, Stuart and Matthews, Nik and Treisman, Richard
Genes & development, ISSN 0890-9369, 05/2014, Volume 28, Issue 9, pp. 943 - 958
Rho | Signal transduction | Chromatin | MRTF | SRF | TCF | Genetics & Heredity | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Serum - metabolism | Signal Transduction | Fibroblasts - physiology | Serum Response Factor - metabolism | Actins - metabolism | CLOCK Proteins - genetics | Circadian Clocks - genetics | Animals | Period Circadian Proteins - metabolism | Period Circadian Proteins - genetics | Mice | Transcription, Genetic - genetics | Mitogen-Activated Protein Kinases - metabolism | Influence | Transcription factors | Cellular signal transduction | Research | Genetic transcription | Rho(D) immune globulin | Index Medicus | signal transduction | Research Paper | chromatin
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11. Full Text Mutual dependence of the MRTF-SRF and YAP-TEAD pathways in cancer-associated fibroblasts is indirect and mediated by cytoskeletal dynamics
by Foster, Charles T and Gualdrini, Francesco and Treisman, Richard
Genes & development, ISSN 0890-9369, 12/2017, Volume 31, Issue 23-24, pp. 2361 - 2375
Cancer-associated fibroblast | MRTF | TEAD | Transcription | SRF | YAP | Mechanotransduction | Genetics & Heredity | Life Sciences & Biomedicine | Developmental Biology | Science & Technology | Cell Biology | Transcriptional Activation - genetics | Signal Transduction | Humans | Transforming Growth Factor beta1 - metabolism | Gene Expression Regulation, Neoplastic | Gene Expression Profiling | Phosphoproteins - genetics | Phosphoproteins - metabolism | DNA-Binding Proteins - metabolism | Transcription Factors - metabolism | Animals | Adaptor Proteins, Signal Transducing - genetics | Mammary Neoplasms, Animal - physiopathology | Trans-Activators - genetics | Cell Line, Tumor | Cytoskeleton - metabolism | Female | Trans-Activators - metabolism | Mice | Adaptor Proteins, Signal Transducing - metabolism | Cell Cycle Proteins | Cancer-Associated Fibroblasts - physiology | Index Medicus | cancer-associated fibroblast | transcription | mechanotransduction | Research Paper
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