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animals (28) 28
phosphorylation (27) 27
biochemistry & molecular biology (24) 24
humans (24) 24
msk (24) 24
mice (19) 19
ribosomal protein s6 kinases, 90-kda - metabolism (15) 15
cell biology (13) 13
cell line (13) 13
mapk, mitogen-activated protein kinase (13) 13
activation (12) 12
ribosomal protein s6 kinases, 90-kda - genetics (11) 11
creb (10) 10
mitogens (10) 10
msk, mitogen- and stress-activated protein kinase (10) 10
acetylation (9) 9
erk (9) 9
expression (9) 9
histones - metabolism (9) 9
p38 (9) 9
protein kinases (9) 9
research article (9) 9
gene-expression (8) 8
mapk (8) 8
activated protein-kinase (7) 7
amino acid sequence (7) 7
enzyme activation (7) 7
erk, extracellular-signal-regulated kinase (7) 7
map kinase (7) 7
mitogen- and stress-activated protein kinase (7) 7
mitogen-activated protein kinase (7) 7
neurosciences (7) 7
protein kinase inhibitors - pharmacology (7) 7
rats (7) 7
ribosomal protein s6 kinases, 90-kda - antagonists & inhibitors (7) 7
ribosomal s6 kinase (7) 7
biophysics (6) 6
egf, epidermal growth factor (6) 6
gst, glutathione s-transferase (6) 6
histone h3 (6) 6
kinase (6) 6
mitogen-activated protein kinases - metabolism (6) 6
p90 ribosomal s6 kinase (6) 6
pkb, protein kinase b (6) 6
rsk (6) 6
rsk, p90 ribosomal s6 kinase (6) 6
stress-induced phosphorylation (6) 6
c-fos (5) 5
cancer (5) 5
cell proliferation (5) 5
cells, cultured (5) 5
enzyme inhibitors - pharmacology (5) 5
female (5) 5
histone h3 phosphorylation (5) 5
immunology (5) 5
in-vivo (5) 5
inflammation (5) 5
macrophages (5) 5
male (5) 5
molecular sequence data (5) 5
oncology (5) 5
p38 mitogen-activated protein kinases - metabolism (5) 5
pathway (5) 5
pdk1, phosphoinositide-dependent kinase 1 (5) 5
protein binding (5) 5
protein-serine-threonine kinases - metabolism (5) 5
proteins (5) 5
signal transduction (5) 5
cell nucleus - metabolism (4) 4
chromatin (4) 4
creb, camp-response-element-binding protein (4) 4
cyclic amp response element-binding protein - metabolism (4) 4
embryonic stem-cells (4) 4
extracellular-signal-regulated kinase (4) 4
identification (4) 4
jnk, c-jun n-terminal kinase (4) 4
kinases (4) 4
map kinases (4) 4
mice, knockout (4) 4
msk1 (4) 4
transcription (4) 4
transcription, genetic (4) 4
analysis (3) 3
apoptosis (3) 3
binding (3) 3
breast cancer (3) 3
cell line, tumor (3) 3
conserved sequence (3) 3
dmem, dulbecco's modified eagle's medium (3) 3
docking site (3) 3
element-binding protein (3) 3
extracellular signal-regulated map kinases - metabolism (3) 3
genetics & heredity (3) 3
gsk3, glycogen synthase kinase 3 (3) 3
ha, haemagglutinin (3) 3
histone (3) 3
il-12 (3) 3
life sciences (3) 3
lipopolysaccharides - pharmacology (3) 3
lps, lipopolysaccharide (3) 3
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Journal Article
Biochemical journal, ISSN 1470-8728, 2007, Volume 408, Issue 3, pp. 297 - 315
... (mitogen-activated protein kinase) isoforms, PI-103 and wortmannin to be used in parallel to inhibit phosphatidylinositol (phosphoinositide... 
Drug discovery | Kinase profiling | Protein kinase | Anti-cancer drugs | Inhibitor specificity | RHO-ASSOCIATED KINASE | TUMOR PROGRESSION | FAMILY-MEMBERS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL-PROLIFERATION | protein kinase | P38 MAP KINASE | CYCLIN-DEPENDENT KINASES | RECEPTOR TYROSINE KINASES | drug discovery | kinase profiling | SB 203580 | anti-cancer drugs | ISOFORMS IN-VITRO | P90 RSK | inhibitor specificity | Amino Acid Sequence | Cell Line | Phosphorylation | Recombinant Proteins - antagonists & inhibitors | Animals | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Humans | Drug Design | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Mitogen-Activated Protein Kinases - metabolism | Spodoptera | Yes1, Yamaguchi sarcoma viral oncogene homologue 1 | CSK, C-terminal Src kinase | Lck, lymphocyte cell-specific protein-tyrosine kinase | EGF, epidermal growth factor | FGF-R, fibroblast-growth-factor receptor | PAK, p21-activated protein kinase | PDK, 3-phosphoinositide-dependent protein kinase | PI3K, phosphatidylinositol (phosphoinositide) 3-kinase | NEK, NIMA (never in mitosis in Aspergillus nidulans)-related kinase | RSK, p90 ribosomal S6 kinase | HEK-293 cells, human embryonic kidney-293 cells | VEGF, vascular endothelial growth factor (vasoendothelial growth factor) | EF2K, elongation-factor-2 kinase | CK, casein kinase | PTEN, phosphatase and tensin homologue deleted on chromosome 10 | ERK, extracellular-signal-regulated kinase | ATM, ataxia telangiectasia mutated | SRPK, serine-arginine protein kinase | IL-1, interleukin 1 | MNK, MAPK-integrating protein kinase | ROCK, Rho-dependent protein kinase | CaMKK, CaMK kinase | GST, glutathione transferase | MKK1, MAPK kinase-1 (also called MEK1, MAPK or ERK kinase 1) | GAK, cyclin G-associated kinase | FMK, fluoromethylketone | MST, mammalian homologue Ste20-like kinase | PKA, cAMP-dependent protein kinase | FKBP, FK506-binding protein | PPAR, peroxisome-proliferator-activated receptor | IKK, inhibitory κB kinase | PH, pleckstrin homology | MBP, myelin basic protein | AICAR, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside | MAPKAP-K, MAPK-activated protein kinase | Sf21, Spodoptera frugiperda (fall armyworm) 21 | MARK, microtubule-affinity-regulating kinase | PIM, provirus integration site for Moloney murine leukaemia virus | LPS, lipopolysaccharide | MSK, mitogen- and stress-activated protein kinase | MAPK, mitogen-activated protein kinase | MELK, maternal embryonic leucine-zipper kinase | His6, hexahistidine | CAK, cyclin-dependent kinase-activating kinase | Eph-A2, Ephrin A2 receptor | PLK, polo-like kinase | ATF2, activating transcription factor 2 | PKD, protein kinase D | Src, sarcoma kinase | AMPK, AMP-activated protein kinase | MMS, methyl methanesulfonate | CHK, checkpoint kinase | JNK, c-Jun N-terminal kinase | TORC1, mTOR (mammalian target of rapamycin)–raptor (regulatory associated protein of mTOR) complex | BRSK, brain-specific kinase | RIP2, receptor-interacting protein 2 | IGF-1, insulin-like growth factor-1 | S6K1, S6 kinase 1 | DYRK, dual-specificity tyrosine-phosphorylated and -regulated kinase | HIPK, homeodomain-interacting protein kinase | ZMP, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside monophosphate | PRAK, p38-regulated activated kinase | PKC, protein kinase C | Src-I1, Src inhibitor 1 | TANK, TRAF (tumour-necrosis-factor-receptor-associated factor)-family-member-associated nuclear factor κB activator | NFAT, nuclear factor for activated T-cells | PHK, phosphorylase kinase | GSK3, glycogen synthase kinase 3 | PKB, protein kinase B (also called Akt) | CaMK, calmodulin-dependent kinase | CDK, cyclin-dependent protein kinase | NDRG, N-myc downstream-regulated gene | SmMLCK, smooth-muscle myosin light-chain kinase | TBK1, TANK-binding kinase 1 | PRK, protein kinase C-related kinase | SGK, serum- and glucocorticoid-induced kinase
Journal Article
Biochemical journal, ISSN 1470-8728, 2007, Volume 401, Issue 1, pp. 29 - 38
... (p90 ribosomal S6 kinase) and MSK (mitogen- and stress-activated protein kinase), which then mediate many of the physiological processes that are regulated by these extracellular agonists... 
Kinase-specific inhibitor | Phosphorylation | p90 ribosomal S6 kinase (RSK) | BI-D1870 | Mitogen-activated protein kinase (MAPK) | ACTIVATED PROTEIN-KINASE | MAP KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | mitogen-activated protein kinase (MAPK) | MSK1 | INDUCTION | IDENTIFICATION | INACTIVATION | CREB | GROWTH | BI-DI870 | SUPPRESSES | phosphorylation | kinase-specific inhibitor | Cell Line | Pteridines - pharmacology | Humans | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | Rats | Ribosomal Protein S6 Kinases, 90-kDa - metabolism | Animals | Ribosomal Protein S6 Kinases, 90-kDa - genetics | Ribosomal Protein S6 Kinases, 90-kDa - antagonists & inhibitors | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Kinetics | Chromones - pharmacology | Isoenzymes - antagonists & inhibitors | MES, mouse embryonic stem | PI3K, phosphoinositide 3-kinase | EGF, epidermal growth factor | PKA, cAMP-dependent protein kinase A | FKHR, forkhead in rhabdosarcoma transcription factor | RSK, p90 ribosomal S6 kinase | JNK, c-Jun N-terminal kinase | CREB, cAMP-response-element-binding protein | SGK1, serum- and glucocorticoid-induced kinase-1 | PDK1, phosphoinositide-dependent kinase 1 | PKB, protein kinase B | Lck, lymphocyte kinase | ROCK, Rho-dependent protein kinase | MKK1, MAPK kinase-1 | protein kinase G | AGC, cAMP-dependent protein kinase | protein kinase C | HEK-293, human embryonic kidney 293 | ERK1, extracellular-signal-regulated kinase 1 | GST, glutathione S-transferase | PKC, protein kinase C | S6K, p70 ribosomal S6 kinase | PH, pleckstrin homology | PLK1, polo-like kinase 1 | CK1, casein kinase-1 | FBS, foetal bovine serum | MSK, mitogen- and stress-activated protein kinase | CDK2–A, cyclin-dependent kinase 2 complexed with cyclin A | DYRK1a, dual-specificity tyrosine-phosphorylated and -regulated kinase 1a | GSK3α, glycogen synthase kinase 3α | MAPK, mitogen-activated protein kinase
Journal Article
Book Review
FEBS letters, ISSN 0014-5793, 2001, Volume 496, Issue 1, pp. 44 - 48
The specificity of 4,5,6,7-tetrabromo-2-azabenzimidazole (TBB), an ATP/GTP competitive inhibitor of protein kinase casein kinase-2 (CK2... 
Casein kinase | Inhibitor | Casein kinase-2 | Protein phosphorylation | Protein kinase | nCK, native casein kinase | OA, okadaic acid | PRAK, p38-regulated/activated kinase | CSK, C-terminal Src kinase | AMPK, AMP-activated protein kinase | CHK, checkpoint kinase | JNK, c-Jun N-terminal kinase | MAPKAP, MAPK-activated protein kinase | p70S6K, p70 ribosomal protein S6 kinase | CK, casein kinase | SAPK, stress-activated protein kinase | PDK, 3-phosphoinositide-dependent kinase | ROCK, Rho-dependent protein kinase | CDK, cyclin-dependent kinase | G-CK, Golgi casein kinase | PKC, protein kinase C | MKK, MAPK kinase (also called MEK) | PKA, cAMP-dependent protein kinase | DRB, 1-(β-D-ribofuranosyl)-5,6-dichlorobenzimidazole | PHK, phosphorylase kinase | GSK3, glycogen synthase kinase 3 | PKB, protein kinase B (also called Akt) | rCK, recombinant casein kinase | ERK, extracellular signal-regulated kinase | HS1, hematopoietic lineage cell-specific protein 1 | MSK, mitogen- and stress-activated protein kinase | TBB, 4,5,6,7-tetrabromo-2-azabenzimidazole or 4,5,6,7-tetrabromobenzotriazole | MAPK, mitogen-activated protein kinase | SGK, serum- and glucocorticoid-induced kinase | CATALYTIC SUBUNIT | ZEA-MAYS | TYROSINE KINASE | CRYSTAL-STRUCTURE | COMPETITIVE INHIBITOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | protein phosphorylation | IMMUNOPHILIN FPR3 | SACCHAROMYCES-CEREVISIAE | protein kinase | CELL BIOLOGY | casein kinase | BIOPHYSICS | inhibitor | CELL-CYCLE | BETA-SUBUNIT | casein kinase-2 | MAMMARY-GLAND | Protein Kinases - metabolism | Jurkat Cells - cytology | Protein Kinases - drug effects | Casein Kinase II | Emodin - pharmacology | Jurkat Cells - metabolism | Humans | Enzyme Inhibitors - pharmacology | Protein-Serine-Threonine Kinases - genetics | Substrate Specificity | Adenosine Triphosphate | Binding Sites - genetics | Binding, Competitive - drug effects | Triazoles - pharmacology | Triazoles - metabolism | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Binding Sites - drug effects | Protein-Serine-Threonine Kinases - metabolism | Staurosporine - pharmacology | Amino Acid Substitution | Jurkat Cells - drug effects
Journal Article
Cancer prevention research (Philadelphia, Pa.), ISSN 1940-6207, 01/2014, Volume 7, Issue 1, pp. 74 - 85
Journal Article
Biochemical journal, ISSN 1470-8728, 2005, Volume 390, Issue 3, pp. 749 - 759
MSK (mitogen- and stress-activated protein kinase) 1 and MSK2 are kinases activated downstream of either the ERK... 
Nurr1 | Nur77 | p38 | Mitogen- and stress-activated protein kinase (MSK) | Nor1 | Extracellular-signal-regulated kinase (ERK) | mitogen-and stress-activated protein kinase (MSK) | NEGATIVE INHIBITOR | ACTIVATED PROTEIN-KINASE | STRESS-INDUCED PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | ELEMENT-BINDING PROTEIN | NERVE GROWTH-FACTOR | extracellular-signal-regulated kinase (ERK) | MEMBRANE DEPOLARIZATION | NGFI-B | EMBRYONIC STEM-CELLS | GENE-EXPRESSION | NF-KAPPA-B | Tetradecanoylphorbol Acetate | Ribosomal Protein S6 Kinases - metabolism | Nuclear Receptor Subfamily 4, Group A, Member 1 | Nuclear Receptor Subfamily 4, Group A, Member 2 | MAP Kinase Signaling System | CREB-Binding Protein - metabolism | Mitogen-Activated Protein Kinase Kinases - metabolism | Ribosomal Protein S6 Kinases, 90-kDa - metabolism | Receptors, Thyroid Hormone - genetics | Fibroblasts | Transcription, Genetic | Promoter Regions, Genetic | Cells, Cultured | Receptors, Cytoplasmic and Nuclear - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Nerve Tissue Proteins - genetics | Tumor Necrosis Factor-alpha | Epidermal Growth Factor | Mice, Knockout | Animals | Anisomycin | Receptors, Steroid - genetics | Ribosomal Protein S6 Kinases, 90-kDa - genetics | Mice | Ribosomal Protein S6 Kinases - genetics | TCR, T-cell receptor | AP-1, activator protein-1 | EGF, epidermal growth factor | NGFI-B, NGF-induced B factor | TNF, tumour necrosis factor α | NGF, nerve growth factor | CRE, cAMP response element | MEF2D, myocyte-enhancer-binding factor 2D | mitogen- and stress-activated protein kinase (MSK) | ATF1, activating transcription factor-1 | ERK, extracellular-signal-regulated kinase | PKI, PKA inhibitor | DMEM, Dulbecco's modified Eagle's medium | CREB, CRE-binding protein | MEF, murine embryonic fibroblast | NBRE, NGFI-B response element | MSK, mitogen- and stress-activated protein kinase | MAPK, mitogen-activated protein kinase | PKA, protein kinase A
Journal Article
FEBS letters, ISSN 0014-5793, 2003, Volume 550, Issue 1, pp. 107 - 113
The receptor for advanced glycation end-products (RAGE)-mediated cellular activation through the mitogen-activated protein kinase (MAPK... 
Extracellular signal-regulated kinase | Receptor for advanced glycation end-products | Amphoterin | ERK, extracellular signal-regulated kinase | RSK, ribosomal S6 kinase | RAGE, receptor for AGE | 2D-PAGE, two-dimensional polyacrylamide gel electrophoresis | MSK, mitogen- and stress-activated protein kinase | AGE, advanced glycation end-product | MnK, MAPK-interacting kinase | MAPK, mitogen-activated protein kinase | extracellular signal-regulated kinase | DNA-BINDING | amphoterin | BIOCHEMISTRY & MOLECULAR BIOLOGY | FACTOR-KAPPA-B | MAP KINASES | CELL BIOLOGY | SUBSTRATE-SPECIFICITY | PTP-SL | INTERACTION MOTIF | BIOPHYSICS | CELL-SURFACE RECEPTOR | NEURITE OUTGROWTH | ENDOTHELIAL-CELLS | ACTIVATED PROTEIN-KINASES | receptor for advanced glycation end-products | Sequence Deletion | Rats, Wistar | Mitogen-Activated Protein Kinases - isolation & purification | Humans | Lung - chemistry | Cytoplasm - metabolism | Male | Receptors, Immunologic - drug effects | HMGB1 Protein - pharmacology | Binding Sites - physiology | Conserved Sequence | Myelin Basic Protein - drug effects | Lung - metabolism | Phosphorylation - drug effects | Receptor for Advanced Glycation End Products | Protein Structure, Tertiary | Amino Acid Sequence | Myelin Basic Protein - metabolism | Cells, Cultured | Rats | Mitogen-Activated Protein Kinase 1 - isolation & purification | Animals | Cell Extracts | Mice | Receptors, Immunologic - genetics | Mitogen-Activated Protein Kinase 3 | Receptors, Immunologic - metabolism | Mitogen-Activated Protein Kinase 1 - metabolism | Mitogen-Activated Protein Kinases - metabolism
Journal Article
Molecular cell, ISSN 1097-2765, 2016, Volume 64, Issue 2, pp. 347 - 361
Journal Article