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1. Full Text Protein kinases of the Hippo pathway: Regulation and substrates
by Avruch, Joseph and Zhou, Dawang and Fitamant, Julien and Bardeesy, Nabeel and Mou, Fan and Barrufet, Laura Regué
Seminars in Cell and Developmental Biology, ISSN 1084-9521, 09/2012, Volume 23, Issue 7, pp. 770 - 784
The “Hippo” signaling pathway has emerged as a major regulator of cell proliferation and survival in metazoans. The pathway, as delineated by genetic and... 
Mst1/2 | ndr1/2 | Protein kinase | Mob1 | Hippo | Lats1/2 | Ndr1/2 | FISSION YEAST | ORGAN SIZE CONTROL | DEVELOPMENTAL BIOLOGY | HUMAN NDR KINASES | CASPASE CLEAVAGE | CELL BIOLOGY | DROSOPHILA TUMOR-SUPPRESSOR | STE20-LIKE KINASE | MST1 KINASE | SIGNALING PATHWAY | CELL-CYCLE EXIT | PROMOTES APOPTOSIS | Protein Kinases - metabolism | Animals | Signal Transduction | Mitosis | Humans | Substrate Specificity | Intracellular Signaling Peptides and Proteins - metabolism | Enzyme Activation | Genetic research | T cells | Muscle proteins | Actin | Protein kinases | Integrins | Lats1 | ndr1 | Mst1
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2. Full Text The hippo pathway: Immunity and cancer
by Taha, Zaid and Janse van Rensburg, Helena J and Yang, Xiaolong
Cancers, ISSN 2072-6694, 04/2018, Volume 10, Issue 4, p. 94
Since its discovery, the Hippo pathway has emerged as a central signaling network in mammalian cells. Canonical signaling through the Hippo pathway core... 
Hippo pathway | Immunology | Immunotherapy | PD-L1 | YAP | Inflammation | LATS1/2 | MST1/2 | TAZ | Cancer | KINASE MST1 | MST1 DEFICIENCY | SELF-RENEWAL | PROLIFERATION | ONCOLOGY | inflammation | SIGNALING PATHWAY | CYCLE EXIT | immunotherapy | REGULATORY T-CELLS | TUMOR-SUPPRESSOR | cancer | immunology | PROMOTES APOPTOSIS | Homeostasis | Signal transduction | Immune response | Leukocytes | Mammalian cells
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3. Full Text Mst1 inhibits Sirt3 expression and contributes to diabetic cardiomyopathy through inhibiting Parkin-dependent mitophagy
by Wang, Haichang and Wang, Shanjie and Zhao, Zhijing and Fan, Yanhong and Zhang, Mingming and Feng, Xinyu and Lin, Jie and Hu, Jianqiang and Cheng, Zheng and Sun, Chuang and Sun, Dongdong and Liu, Tingting and Xiong, Zhenyu and Yang, Zhi
BBA - Molecular Basis of Disease, ISSN 0925-4439, 07/2019, Volume 1865, Issue 7, pp. 1905 - 1914
Mitochondrial dysfunction contributes to heart failure induced mortality in approximately 80% of diabetic patients. Mitophagy degrades defective mitochondria... 
Sirt3 | Diabetic cardiomyopathy | Mitophagy | Mst1 | Parkin
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4. Full Text Melatonin activates Parkin translocation and rescues the impaired mitophagy activity of diabetic cardiomyopathy through Mst1 inhibition
by Wang, Shanjie and Zhao, Zhijing and Feng, Xinyu and Cheng, Zheng and Xiong, Zhenyu and Wang, Tingting and Lin, Jie and Zhang, Mingming and Hu, Jianqiang and Fan, Yanhong and Reiter, Russel J and Wang, Haichang and Sun, Dongdong
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 10/2018, Volume 22, Issue 10, pp. 5132 - 5144
Mitophagy eliminates dysfunctional mitochondria and thus plays a cardinal role in diabetic cardiomyopathy ( DCM ). We observed the favourable effects of... 
mitophagy | diabetic cardiomyopathy | parkin | melatonin | mammalian Ste20‐like kinase 1, Mst1 | mitochondrion | mammalian Ste20-like kinase 1, Mst1 | MEDICINE, RESEARCH & EXPERIMENTAL | MITOFUSIN 2 | MITOCHONDRIAL BIOGENESIS | Mst1 | DAMAGED MITOCHONDRIA | INJURY | MECHANISMS | UP-REGULATING AUTOPHAGY | CELL BIOLOGY | HEART | mammalian Ste20-like kinase 1 | PINK1 | ANTIOXIDANT | DEGRADATION | Melatonin | Cardiomyopathy | Heart diseases | Analysis | Heart | Translocation | Flow cytometry | Phosphorylation | Diabetes mellitus | Phagosomes | Lysosomes | Cardiomyocytes | Electron microscopy | Autophagy | Mitochondria | Morphology | Quality control | Mice | Parkin protein | Diabetes | Inhibition | Original
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5. Full Text IMMUNOBIOLOGY A loss of naivete
by Risma, K
BLOOD, ISSN 0006-4971, 04/2012, Volume 119, Issue 15, pp. 3371 - 3372
FOXO | MST1 | HEMATOLOGY
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6. Full Text Hepatic Hippo signaling inhibits pro-tumoral microenvironment to suppress hepatocellular carcinoma
by Kim, Wantae and Khan, Sanjoy Kumar and Liu, Yuchen and Xu, Ruoshi and Park, Ogyi and He, Yong and Cha, Boksik and Gao, Bin and Yang, Yingzi
Gut, ISSN 0017-5749, 9/2018, Volume 67, Issue 9, pp. 1692 - 1703
Mst2 | Mcp1 | Hippo Signaling | inflammation | Mst1 | Hepatocellular carcinoma | Macrophage
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7. Full Text The MEK-ERK-MST1 Axis Potentiates the Activation of the Extrinsic Apoptotic Pathway during GDC-0941 Treatment in Jurkat T Cells
by Novakova, J and Talacko, P and Novak, P and Valis, K
CELLS, ISSN 2073-4409, 02/2019, Volume 8, Issue 2, p. 191
The discrete activation of individual caspases is essential during T-cell development, activation, and apoptosis. Humans carrying nonfunctional caspase-8 and... 
KINASE MST1 | PROTEIN | SPECIFICITY | PHOSPHORYLATION | HIPPO PATHWAY | apoptosis | AKT | DEATH | CASPASE CLEAVAGE | caspase | CELL BIOLOGY | REGULATOR | MEK | INHIBITION | PI3K | EXPRESSION | Hippo/MST1 | ERK
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8. Full Text Non-canonical Hippo signaling in the regulation of leukocyte function
by Kurz, Angela R.M and Catz, Sergio D and Sperandio, Markus
Trends in immunology, ISSN 1471-4906, 8/2018, Volume 39, Issue 8, pp. 656 - 669
The mammalian sterile 20-like kinases are central constituents of the evolutionary ancient canonical Hippo pathway regulating cell proliferation and survival.... 
MST2 | vesicle transport | Hippo pathway | MST1 | leukocyte
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9. Full Text The transcriptional coactivator TAZ regulates reciprocal differentiation of T(H)17 cells and T-reg cells
by Geng, J and Yu, SJ and Zhao, H and Sun, XF and Li, X and Wang, P and Xiong, XL and Hong, LX and Xie, CC and Gao, JH and Shi, YR and Peng, JQ and Johnson, RL and Xiao, NM and Lu, LR and Han, JH and Zhou, DW and Chen, LF
NATURE IMMUNOLOGY, ISSN 1529-2908, 07/2017, Volume 18, Issue 7, pp. 800 - 800
An imbalance in the lineages of immunosuppressive regulatory T cells (T-reg cells) and the inflammatory T(H)17 subset of helper T cells leads to the... 
EPITHELIAL-MESENCHYMAL TRANSITION | KINASE MST1 | TGF-BETA | ROR-GAMMA-T | IN-VIVO | HIPPO PATHWAY | IMMUNOLOGY | CANCER | FOXP3 | LYMPHOCYTE TRAFFICKING | TH17 CELLS
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10. Full Text YAP regulates neural progenitor cell number via the TEA domain transcription factor
by Cao, Xinwei and Pfaff, Samuel L and Gage, Fred H
Genes and Development, ISSN 0890-9369, 12/2008, Volume 22, Issue 23, pp. 3320 - 3334
Tight control of cell proliferation is essential for proper growth during development and for tissue homeostasis in mature animals. The evolutionarily... 
Chick spinal cord | CNS | Mst1/2 | Neural stem cells | Neurogenesis | Lats1/2 | NERVOUS-SYSTEM | GROWTH-CONTROL | chick spinal cord | neural stem cells | DROSOPHILA-MELANOGASTER | PROTEIN-KINASE | HIPPO PATHWAY | MAMMALIAN DEVELOPMENT | DEVELOPMENTAL BIOLOGY | TEAD/TEF FAMILY | CELL BIOLOGY | GENETICS & HEREDITY | neurogenesis | SIZE-CONTROL | VERTEBRATE NEUROGENESIS | TUMOR-SUPPRESSOR PATHWAY | Cell Line | Avian Proteins - metabolism | DNA-Binding Proteins - physiology | Transcription Factors - physiology | Cell Proliferation | Signal Transduction | Humans | Neural Tube - physiology | Neuropeptides - metabolism | Chick Embryo | DNA-Binding Proteins - metabolism | Animals | Transfection | Basic Helix-Loop-Helix Transcription Factors - metabolism | Cell Cycle | Cyclins - metabolism | Neurons - physiology | Stem Cells - physiology | Cell Differentiation | Nuclear Proteins - physiology | Cyclin D | Muscle Proteins - physiology | Apoptosis | Cell proliferation | Neurogenetics | Analysis | Stem cells | Genetic aspects | Genetic transcription | Research | Lats1 | Mst1 | Research Paper
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11. Full Text Berberine induced modulation of PHLPP2-Akt-MST1 kinase signaling is coupled with mitochondrial impairment and hepatoma cell death
by Saxena, Sugandh and Shukla, Shatrunajay and Kakkar, Poonam
Toxicology and Applied Pharmacology, ISSN 0041-008X, 05/2018, Volume 347, pp. 92 - 103
Pleckstrin homology domain leucine-rich repeat protein phosphatase 2 (PHLPP2) has been known to exert tumor suppressive activity for long without much... 
PHLPP2 | Berberine | Akt | Mst1 | Bim | Apoptosis | AQUEOUS EXTRACT | INDUCED APOPTOSIS | NUCLEAR TRANSLOCATION | BREAST-CANCER | HEPATOCELLULAR-CARCINOMA | MST1 KINASE | BH3-ONLY PROTEIN BIM | PHARMACOLOGY & PHARMACY | TOXICOLOGY | TREATED HEPG2 CELLS | PHLPP | Index Medicus
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12. Full Text MST1 is a novel regulator of apoptosis in pancreatic beta-cells
by Ardestani, Amin and Paroni, Federico and Azizi, Zahra and Kaur, Supreet and Khobragade, Vrushali and Yuan, Ting and Frogne, Thomas and Tao, Wufan and Oberholzer, Jose and Pattou, Francois and Conte, Julie Kerr and Maedler, Kathrin
Nature medicine, ISSN 1078-8956, 4/2014, Volume 20, Issue 4, pp. 385 - 397
Apoptotic cell death is a hallmark of the loss of insulin producing beta-cells in all forms of diabetes mellitus. Current treatment fails to halt the decline... 
apoptosis | beta-cells | diabetes | pancreas | MST1
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13. Full Text Role of Hippo signaling in regulating immunity
by Hong, Lixin and Li, Xun and Zhou, Dawang and Geng, Jing and Chen, Lanfen
Cellular and Molecular Immunology, ISSN 1672-7681, 12/2018, Volume 15, Issue 12, pp. 1003 - 1009
The Hippo signaling pathway has been established as a key regulator of organ size control, tumor suppression, and tissue regeneration in multiple organisms.... 
MST1/2 | innate immunity | The Hippo pathway | adaptive immunity | HOMEOSTASIS | LYMPHOCYTE | STABILITY | MST1 | PROLIFERATION | IMMUNOLOGY | RAPL | PROTEIN-KINASES | PATHWAY | TUMORIGENESIS | T-CELLS
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14. Full Text Mst1/2 Kinases Modulate Glucose Uptake for Osteoblast Differentiation and Bone Formation
by Li, Wenling and Deng, Yujie and Feng, Bo and Mak, Kingston King‐Lun
Journal of Bone and Mineral Research, ISSN 0884-0431, 06/2018, Volume 33, Issue 6, pp. 1183 - 1195
Bone formation and bone homeostasis are energy-expensive processes. How they are being regulated by energy needs is not completely understood. This is of high... 
MST1/2 KINASES | OSTEOBLAST DIFFERENTIATION | GLUCOSE HOMEOSTASIS | BONE REMODELING | HOMEOSTASIS | HIPPO-YAP PATHWAY | ORGAN SIZE CONTROL | MST1 | TRANSCRIPTION | SUPPRESSION | 2 KINASES | DIABETES-MELLITUS | AMPK-MEDIATED REGULATION | ENDOCRINOLOGY & METABOLISM | ENERGY-METABOLISM | TYPE-1 | EXPRESSION | Glucose metabolism | Glucose | Streptozocin | Protein kinases | Analysis | Dextrose | Glucose transporter | Cbfa-1 protein | AMP | Bone remodelling | Diabetes mellitus | Homeostasis | Bone turnover | Kinases | Osteoblasts | Yes-associated protein | Bone growth | Osteoblastogenesis | Protein kinase | Proteasomes | Diabetes | Bone loss | Osteogenesis
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15. Full Text Hippo Signaling in the Immune System
by Zhang, Haitao and Zhang, Yuchao and Zhao, Bin
Trends in Biochemical Sciences, ISSN 0968-0004, 02/2018, Volume 43, Issue 2, pp. 77 - 80
Hippo signaling has a pivotal role in organ size control, tissue regeneration, and cancer. Recent studies have demonstrated critical functions of Hippo... 
YAP | cancer immunity | innate immunity | autoimmunity | TAZ | Hippo | Autoimmunity | Innate immunity | Cancer immunity | CELLS | PATHWAY | CANCER | BIOCHEMISTRY & MOLECULAR BIOLOGY | MST1
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16. Full Text Noncanonical Hippo Signalling in the Regulation of Leukocyte Function
by Kurz, Angela R.M and Catz, Sergio D and Sperandio, Markus
Trends in Immunology, ISSN 1471-4906, 08/2018, Volume 39, Issue 8, pp. 656 - 669
The mammalian sterile 20-like (MST) kinases are central constituents of the evolutionary ancient canonical Hippo pathway regulating cell proliferation and... 
MST2 | vesicle transport | Hippo pathway | MST1 | leukocyte | GRISCELLI-SYNDROME | ADHESION | MST1 DEFICIENCY | INFLAMMATION | IN-VIVO | RAB27A | EXTRACELLULAR-MATRIX | NEUTROPHIL TRANSMIGRATION | IMMUNOLOGY | T-CELLS | KINASES | Autoimmune Diseases - genetics | Biological Evolution | Severe Combined Immunodeficiency - genetics | Animals | Signal Transduction | MAP Kinase Kinase Kinases - genetics | Humans | MAP Kinase Kinase Kinases - metabolism | Mice | Leukocytes - metabolism | Protein-Serine-Threonine Kinases - metabolism | Cell proliferation | Cell survival | Severe combined immunodeficiency | Neutrophils | Cell division | Infections | Leukocytes | Mammals | Kinases | Proteins | White blood cells | Genotype & phenotype | Signal transduction | Cell growth | Stem cells | Regulation | Mutation
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17. Full Text The Nore1B/Mst1 Complex Restrains Antigen Receptor-Induced Proliferation of Naïve T Cells
by Dawang Zhou and Benjamin D. Medoff and Lanfen Chen and Lequn Li and Xian-feng Zhang and Maria Praskova and Matthew Liu and Aimee Landry and Richard S. Blumberg and Vassiliki A. Boussiotis and Ramnik Xavier and Joseph Avruch
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2008, Volume 105, Issue 51, pp. 20321 - 20326
The Mst1 and Mst2 protein kinases are the mammalian homologs of hippo, a major inhibitor of cell proliferation in Drosophila. Mst1 is most abundant in lymphoid... 
T lymphocytes | Spleen | Phosphorylation | Cell growth | Messenger RNA | Lymphocytes | Mice | Apoptosis | Tumors | T cell antigen receptors | Mst1 knockout | Mob1 | RAPL | Stk4 | Hippo | ACTIVATION | hippo | DENDRITIC CELL | PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | MST1 | HIPPO PATHWAY | DROSOPHILA | GROWTH | TUMOR-SUPPRESSOR | SIZE-CONTROL | PROMOTES APOPTOSIS | Protein Kinases - metabolism | Adaptor Proteins, Signal Transducing - physiology | Animals | Cell Proliferation | T-Lymphocytes - cytology | Lymphocyte Activation | Protein-Serine-Threonine Kinases - physiology | Receptors, Antigen, T-Cell - physiology |