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Seminars in Cell and Developmental Biology, ISSN 1084-9521, 09/2012, Volume 23, Issue 7, pp. 770 - 784
Journal Article
Cancers, ISSN 2072-6694, 04/2018, Volume 10, Issue 4, p. 94
Since its discovery, the Hippo pathway has emerged as a central signaling network in mammalian cells. Canonical signaling through the Hippo pathway core... 
Hippo pathway | Immunology | Immunotherapy | PD-L1 | YAP | Inflammation | LATS1/2 | MST1/2 | TAZ | Cancer | KINASE MST1 | MST1 DEFICIENCY | SELF-RENEWAL | PROLIFERATION | ONCOLOGY | inflammation | SIGNALING PATHWAY | CYCLE EXIT | immunotherapy | REGULATORY T-CELLS | TUMOR-SUPPRESSOR | cancer | immunology | PROMOTES APOPTOSIS | Homeostasis | Signal transduction | Immune response | Leukocytes | Mammalian cells
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 07/2019, Volume 1865, Issue 7, pp. 1905 - 1914
Mitochondrial dysfunction contributes to heart failure induced mortality in approximately 80% of diabetic patients. Mitophagy degrades defective mitochondria... 
Sirt3 | Diabetic cardiomyopathy | Mitophagy | Mst1 | Parkin
Journal Article
BLOOD, ISSN 0006-4971, 04/2012, Volume 119, Issue 15, pp. 3371 - 3372
Journal Article
Gut, ISSN 0017-5749, 9/2018, Volume 67, Issue 9, pp. 1692 - 1703
Journal Article
CELLS, ISSN 2073-4409, 02/2019, Volume 8, Issue 2, p. 191
The discrete activation of individual caspases is essential during T-cell development, activation, and apoptosis. Humans carrying nonfunctional caspase-8 and... 
KINASE MST1 | PROTEIN | SPECIFICITY | PHOSPHORYLATION | HIPPO PATHWAY | apoptosis | AKT | DEATH | CASPASE CLEAVAGE | caspase | CELL BIOLOGY | REGULATOR | MEK | INHIBITION | PI3K | EXPRESSION | Hippo/MST1 | ERK
Journal Article
Trends in immunology, ISSN 1471-4906, 8/2018, Volume 39, Issue 8, pp. 656 - 669
The mammalian sterile 20-like kinases are central constituents of the evolutionary ancient canonical Hippo pathway regulating cell proliferation and survival.... 
MST2 | vesicle transport | Hippo pathway | MST1 | leukocyte
Journal Article
by Geng, J and Yu, SJ and Zhao, H and Sun, XF and Li, X and Wang, P and Xiong, XL and Hong, LX and Xie, CC and Gao, JH and Shi, YR and Peng, JQ and Johnson, RL and Xiao, NM and Lu, LR and Han, JH and Zhou, DW and Chen, LF
NATURE IMMUNOLOGY, ISSN 1529-2908, 07/2017, Volume 18, Issue 7, pp. 800 - 800
An imbalance in the lineages of immunosuppressive regulatory T cells (T-reg cells) and the inflammatory T(H)17 subset of helper T cells leads to the... 
EPITHELIAL-MESENCHYMAL TRANSITION | KINASE MST1 | TGF-BETA | ROR-GAMMA-T | IN-VIVO | HIPPO PATHWAY | IMMUNOLOGY | CANCER | FOXP3 | LYMPHOCYTE TRAFFICKING | TH17 CELLS
Journal Article
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 05/2018, Volume 347, pp. 92 - 103
Pleckstrin homology domain leucine-rich repeat protein phosphatase 2 (PHLPP2) has been known to exert tumor suppressive activity for long without much... 
PHLPP2 | Berberine | Akt | Mst1 | Bim | Apoptosis | AQUEOUS EXTRACT | INDUCED APOPTOSIS | NUCLEAR TRANSLOCATION | BREAST-CANCER | HEPATOCELLULAR-CARCINOMA | MST1 KINASE | BH3-ONLY PROTEIN BIM | PHARMACOLOGY & PHARMACY | TOXICOLOGY | TREATED HEPG2 CELLS | PHLPP | Index Medicus
Journal Article
Nature medicine, ISSN 1078-8956, 4/2014, Volume 20, Issue 4, pp. 385 - 397
Apoptotic cell death is a hallmark of the loss of insulin producing beta-cells in all forms of diabetes mellitus. Current treatment fails to halt the decline... 
apoptosis | beta-cells | diabetes | pancreas | MST1
Journal Article
Cellular and Molecular Immunology, ISSN 1672-7681, 12/2018, Volume 15, Issue 12, pp. 1003 - 1009
The Hippo signaling pathway has been established as a key regulator of organ size control, tumor suppression, and tissue regeneration in multiple organisms.... 
MST1/2 | innate immunity | The Hippo pathway | adaptive immunity | HOMEOSTASIS | LYMPHOCYTE | STABILITY | MST1 | PROLIFERATION | IMMUNOLOGY | RAPL | PROTEIN-KINASES | PATHWAY | TUMORIGENESIS | T-CELLS
Journal Article
Trends in Biochemical Sciences, ISSN 0968-0004, 02/2018, Volume 43, Issue 2, pp. 77 - 80
Hippo signaling has a pivotal role in organ size control, tissue regeneration, and cancer. Recent studies have demonstrated critical functions of Hippo... 
YAP | cancer immunity | innate immunity | autoimmunity | TAZ | Hippo | Autoimmunity | Innate immunity | Cancer immunity | CELLS | PATHWAY | CANCER | BIOCHEMISTRY & MOLECULAR BIOLOGY | MST1
Journal Article