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Carcinogenesis, ISSN 0143-3334, 08/2012, Volume 33, Issue 8, pp. 1563 - 1571
Journal Article
PLoS ONE, ISSN 1932-6203, 02/2015, Volume 10, Issue 2, p. e0116644
Journal Article
International Journal of Cancer, ISSN 0020-7136, 12/2014, Volume 135, Issue 11, pp. 2569 - 2578
The invasiveness of malignant gliomas is one of the major obstacles in glioma therapy and the reason for the poor survival of patients. Glioma cells infiltrate... 
glioma‐associated microglia/brain macrophages | glioma | TLR | MMP9 | minocycline | glioma-associated microglia/brain macrophages | ACTIVATION | RNA | CANCER | MT1-MMP EXPRESSION | INVASION | INHIBITION | GENE | ONCOLOGY | NEUROINFLAMMATION | MOUSE MODEL | TUMOR-GROWTH | Microglia - metabolism | Toll-Like Receptor 2 - genetics | Minocycline - pharmacology | Humans | Brain Neoplasms - pathology | Brain Neoplasms - metabolism | Immunoenzyme Techniques | Glioma - metabolism | Matrix Metalloproteinase 9 - metabolism | Flow Cytometry | Matrix Metalloproteinase 9 - genetics | Glioma - pathology | Microglia - pathology | Tumor Cells, Cultured | Real-Time Polymerase Chain Reaction | Disease Models, Animal | Macrophages - pathology | Microglia - drug effects | Mice, Inbred C57BL | RNA, Messenger - genetics | Toll-Like Receptor 2 - metabolism | Brain Neoplasms - drug therapy | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Macrophages - metabolism | Animals | Signal Transduction - drug effects | Fluorescent Antibody Technique | Macrophages - drug effects | Anti-Bacterial Agents - pharmacology | Mice | Glioma - drug therapy | Minocycline | Gliomas | Proteases | Analysis | Extracellular matrix | Antibiotics | Kinases | Cancer therapies | Brain cancer | Immune system | Brain | Drinking water | Therapy | Matrix metalloproteinases | Parenchyma | Matrix metalloproteinase | Macrophages | Metastases | Proteins | Signal transduction | Receptors | Glioma cells | Surgery | Toll-like receptors | Microglial cells | Metalloproteinase | Phenotypes | Cell survival | Invasiveness | Survival | Gelatinase B | Microglia | Signaling | Protein kinase | TLR2 protein | Infiltration
Journal Article
Journal Article
Carcinogenesis, ISSN 0143-3334, 2/2009, Volume 30, Issue 2, pp. 356 - 365
Glioblastoma is a severe type of primary brain tumor, and its highly invasive character is considered to be a major therapeutic obstacle. Phospholipase D (PLD)... 
TRANSFORMATION | ACTIVATION | MT1-MMP | ONCOLOGY | GELATINASE-A MMP-2 | MALIGNANT GLIOMAS | PROLIFERATION | FIBROSARCOMA CELLS | NF-KAPPA-B | CANCER | FIBROBLASTS
Journal Article
Journal Article
BMC Cancer, ISSN 1471-2407, 11/2013, Volume 13, Issue 1, p. 517
Journal Article
Cancer Research, ISSN 0008-5472, 02/2011, Volume 71, Issue 3, pp. 1019 - 1028
One of the hallmarks of human pancreatic ductal adenocarcinoma (PDAC) is its pronounced type I collagen-rich fibrotic reaction. Although recent reports have... 
CARCINOMA-CELLS | TYPE-1 MATRIX-METALLOPROTEINASE | CHECKPOINT KINASE-1 | PROTEIN | THERAPY | INHIBITION | EPITHELIAL-CELLS | ONCOLOGY | DUCTAL ADENOCARCINOMA | CHEMORESISTANCE | MALIGNANT PHENOTYPE | RNA, Small Interfering - genetics | Pancreatic Neoplasms - metabolism | HMGA2 Protein - biosynthesis | Humans | Carcinoma, Pancreatic Ductal - metabolism | Collagen Type I - chemistry | Extracellular Matrix - metabolism | Cell Growth Processes - physiology | Deoxycytidine - pharmacology | Drug Resistance, Neoplasm | Extracellular Matrix - chemistry | Carcinoma, Pancreatic Ductal - genetics | Matrix Metalloproteinase 14 - biosynthesis | Pancreatic Neoplasms - drug therapy | HMGA2 Protein - genetics | Antimetabolites, Antineoplastic - pharmacology | Molecular Targeted Therapy - methods | Cell Growth Processes - drug effects | Pancreatic Neoplasms - pathology | Pancreatic Neoplasms - genetics | Carcinoma, Pancreatic Ductal - pathology | Drug Synergism | Up-Regulation - drug effects | Xenograft Model Antitumor Assays | Carcinoma, Pancreatic Ductal - drug therapy | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Mice, Nude | Matrix Metalloproteinase 14 - genetics | Cell Line, Tumor | Mice | RNA, Small Interfering - administration & dosage | Deoxycytidine - analogs & derivatives | Mitogen-Activated Protein Kinase 1 - metabolism | HMGA2 | MT1-MMP | fibrosis | ERK1
Journal Article
ONCOGENE, ISSN 0950-9232, 02/2011, Volume 30, Issue 8, pp. 1002 - 1008
Pancreatic ductal adenocarcinoma (PDAC) is associated with a pronounced collagen-rich fibrosis known as desmoplastic reaction; however, the role of fibrosis in... 
let-7 | TGF-beta 1 | DUCTAL ADENOCARCINOMA | RAS | TUMOR-DEVELOPMENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | collagen | CELL-PROLIFERATION | FAMILY | CELL BIOLOGY | ERK1/2 | MT1-MMP | INVASION | ONCOLOGY | TRANSFORMING GROWTH-FACTOR-BETA-1 | GENETICS & HEREDITY | fibrosis | EXTRACELLULAR-MATRIX | MICRORNA EXPRESSION
Journal Article
FASEB JOURNAL, ISSN 0892-6638, 04/2002, Volume 16, Issue 6, pp. 555 - 564
Journal Article
Brain and Behavior, ISSN 2162-3279, 08/2018, Volume 8, Issue 8, pp. e01079 - n/a
Introduction Despite the increased understanding of treadmill training on angiogenesis of stroke patients, its mechanism is not clearly known. The... 
rehabilitation | angiogenesis | cerebral ischemia | treadmill exercise training | MT1‐MMP | MT1-MMP | MMP-2 | MATRIX-METALLOPROTEINASE MT1-MMP | BEHAVIORAL SCIENCES | TUMOR ANGIOGENESIS | RECK | NEUROSCIENCES | Cysteine | Cerebral ischemia
Journal Article
Journal Article