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Pharmacology Biochemistry and Behavior, ISSN 0091-3057, 12/2012, Volume 103, Issue 2, pp. 425 - 430
CB receptor antagonists proved to be effective anti-obesity drugs, however, their depressive and anxiogenic effects became also evident. Finding solution to... 
Rimonabant | Food intake | Memory | MTEP | Anxiety
Journal Article
Neuropharmacology, ISSN 0028-3908, 09/2004, Volume 47, Issue 3, pp. 342 - 350
Several lines of evidence suggest a crucial involvement of glutamate in the mechanism of action of anxiolytic drugs including the involvement of group I... 
GABA | mGlu5 receptors | Anxiety | MTEP | BZD receptors
Journal Article
Pharmaceuticals, ISSN 1424-8247, 03/2018, Volume 11, Issue 1, p. 24
The Sonogashira cross-coupling, a key step in the syntheses of the mGlu₅ antagonists MMPEP and MTEP, provided an improved three-step method for the preparation... 
MMPEP | antagonist | MTEP | MGlu | Sonogashira cross-coupling | Medical imaging | mGlu5 antagonist
Journal Article
Behavioural Brain Research, ISSN 0166-4328, 02/2016, Volume 298, pp. 32 - 36
•Positive allosteric modulation of mGlu5 facilitates extinction of conditioned fear in postnatal day (P) 17 rats, but not in P24 or adult rats.•Negative... 
Development | Fear | CDPPB | Extinction | MTEP | Mglu5 | ACQUISITION | ANTAGONIST MK-801 | NEUROSCIENCES | MEMORY | AMYGDALA DEPOTENTIATION | LONG-TERM DEPRESSION | BEHAVIORAL SCIENCES | Glutamate | Neurosciences
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 2008, Volume 75, Issue 5, pp. 997 - 1006
Journal Article
Progress in Neuropsychopharmacology & Biological Psychiatry, ISSN 0278-5846, 08/2013, Volume 45, pp. 242 - 249
Chronic amphetamine use results in anxiety-like states after drug cessation. The aim of the study was to determine a role of ionotropic and metabotropic... 
LY354740 | Anxiolytic-like activity | Memantine | Acamprosate | Amphetamine withdrawal | MTEP | Acamprosate$Amphetamine withdrawal$Anxiolytic-like activity$LY354740$Memantine$MTEP | COCAINE-SEEKING BEHAVIOR | INDUCED REINSTATEMENT | PSYCHIATRY | CONDITIONED PLACE PREFERENCE | MGLU RECEPTORS | PSYCHOSTIMULANT WITHDRAWAL | ELEVATED PLUS-MAZE | NEUROSCIENCES | PREFRONTAL CORTEX | CLINICAL NEUROLOGY | NUCLEUS-ACCUMBENS | DRUG-ADDICTION | PHARMACOLOGY & PHARMACY | LOCOMOTOR RESPONSES | Excitatory Amino Acid Antagonists - therapeutic use | Excitatory Amino Acid Agonists - therapeutic use | Substance Withdrawal Syndrome - drug therapy | Male | Anxiety - drug therapy | Thiazoles - therapeutic use | Dose-Response Relationship, Drug | Receptors, Ionotropic Glutamate - antagonists & inhibitors | Anxiety - complications | Bridged Bicyclo Compounds - therapeutic use | Taurine - therapeutic use | Pyridines - therapeutic use | Taurine - analogs & derivatives | Memantine - pharmacology | Bridged Bicyclo Compounds - pharmacology | Rats | Substance Withdrawal Syndrome - complications | Amphetamine - adverse effects | Excitatory Amino Acid Agonists - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Animals | Ligands | Pyridines - pharmacology | Thiazoles - pharmacology | Taurine - pharmacology | Memantine - therapeutic use | Receptors, Metabotropic Glutamate - agonists | Receptors, Metabotropic Glutamate - antagonists & inhibitors | Methyl aspartate | Aspartate | Glutamate | Central nervous system agents
Journal Article
Journal Article
Behavioural Brain Research, ISSN 0166-4328, 2009, Volume 202, Issue 2, pp. 238 - 244
Journal Article
Alcoholism: Clinical and Experimental Research, ISSN 0145-6008, 03/2014, Volume 38, Issue 3, pp. 730 - 738
Background Binge ethanol (EtOH) intake during adolescence leads to an array of behavioral and cognitive consequences including elevated intake of EtOH during... 
Alcohol | Adult | Glutamate | MTEP | Adolescent | Methyl aspartate | Alcohol, Denatured | Pyridine | RNA | Analysis | Mice | Drinking of alcoholic beverages | Teenage girls | Alcohol use
Journal Article
Behavioural Brain Research, ISSN 0166-4328, 10/2014, Volume 273, pp. 23 - 33
Journal Article