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02/2012
Background: Genetic variations represented as single nucleotide polymorphisms (SNPs) vary across the world population. This genetic polymorphism (such as SNPs)... 
south Indian | SULT1A1 | MTRR | MTHFD1 | CBS | SHMT1 | polymorphism | MTR | TYMS
Web Resource
Annals of Clinical and Laboratory Science, ISSN 0091-7370, 01/2019, Volume 49, Issue 1, pp. 112 - 118
Hypertension and hyperhomocysteinemia are both stroke risk factors. plays a vital role in one-carbon metabolism via encoding a protein with three distinct... 
Hypertension | Promoter | Stroke | MTHFD1 | Methylation | Index Medicus
Journal Article
Pharmacogenomics Journal, ISSN 1470-269X, 2004, Volume 4, Issue 1, pp. 66 - 72
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2015, Volume 112, Issue 2, pp. 400 - 405
Journal Article
Journal Article
Clinical and Experimental Hypertension, ISSN 1064-1963, 07/2019, Volume 41, Issue 5, pp. 422 - 427
Objectives: Methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) plays an essential role in folate-mediated one-carbon metabolism which determines both... 
essential hypertension | hyperhomocysteinemia | promoter | MTHFD1 | hypermethylation | HOMOCYSTEINE | METHYLATION | NOVO THYMIDYLATE BIOSYNTHESIS | HYPOMETHYLATION | DISEASE | PHARMACOLOGY & PHARMACY | PERIPHERAL VASCULAR DISEASE | BODY
Journal Article
Clinica e Investigacion en Arteriosclerosis, ISSN 0214-9168, 03/2015, Volume 27, Issue 2, pp. 64 - 73
Introduction and objectives: Cardiovascular medicine is focused on the search for genetic risk markers with predictive and/or prognostic value. Among the... 
Ischemic heart disease | Genotype, Polymorphism, NOS3 | MTHFD1
Journal Article
Molecular Biology Reports, ISSN 0301-4851, 2/2012, Volume 39, Issue 2, pp. 887 - 893
Alterations in folate metabolism may contribute to the process of carcinogenesis by influencing DNA methylation and genomic stability. Polymorphisms in genes... 
Life Sciences | Head and neck cancer | MTHFD1, BHMT and TC2 g enes | Animal Biochemistry | Animal Anatomy / Morphology / Histology | Genetic polymorphism | MTHFD1 BHMT and TC2 genes | MTHFD1, BHMT and TC2 genes | NEURAL-TUBE DEFECTS | BIOCHEMISTRY & MOLECULAR BIOLOGY | HOMOCYSTEINE METHYLTRANSFERASE BHMT | ALCOHOL-CONSUMPTION | BREAST-CANCER | SPINA-BIFIDA | LUNG-CANCER | COLORECTAL-CANCER | BETAINE-HOMOCYSTEINE | ONE-CARBON METABOLISM | SINGLE-NUCLEOTIDE POLYMORPHISMS | Carcinoma, Squamous Cell - epidemiology | Minor Histocompatibility Antigens | Transcobalamins - genetics | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Humans | Risk Factors | Logistic Models | Male | DNA Methylation - genetics | Head and Neck Neoplasms - metabolism | Polymorphism, Restriction Fragment Length | Head and Neck Neoplasms - epidemiology | Polymerase Chain Reaction | Folic Acid - metabolism | Polymorphism, Single Nucleotide - genetics | Female | Head and Neck Neoplasms - genetics | Brazil - epidemiology | Genomic Instability - genetics | Methylenetetrahydrofolate Dehydrogenase (NADP) - genetics | Betaine-Homocysteine S-Methyltransferase - genetics | Enzymes | Squamous cell carcinoma | Genes | DNA synthesis | S-adenosylmethionine | Risk factors | Folic acid | DNA | Physiological aspects | Genetic aspects | Homocysteine | Methylation | Health aspects | DNA methylation | Head & neck cancer | Molecular biology | Polymorphism | Index Medicus
Journal Article
Meta Gene, ISSN 2214-5400, 12/2017, Volume 14, pp. 24 - 29
Folate is one of the B vitamins and essential for cellular functioning because it donates one‑carbon for purine and pyrimidine synthesis, required for DNA... 
Intellectual disability | MTHFD1 G1958A | CBS 844ins68 | Down syndrome | MTR A2756G | PCR-RFLP analysis
Journal Article
International Medical Journal, ISSN 1341-2051, 08/2013, Volume 20, Issue 4, pp. 404 - 408
Journal Article
Journal Article
Behavioural Brain Research, ISSN 0166-4328, 08/2017, Volume 332, pp. 71 - 74
Journal Article
F1000Research, ISSN 2046-1402, 2016, Volume 4, pp. 1 - 19
To investigate the association between the methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) polymorphism rs 2236225 (c.1958G>A) and susceptibility to... 
Developmental Molecular Mechanisms | Genomics
Journal Article
Journal Article
AMERICAN JOURNAL OF CLINICAL NUTRITION, ISSN 0002-9165, 11/2016, Volume 104, Issue 5, pp. 1459 - 1469
Background: Moderately high folic acid intake in pregnant women has led to concerns about deleterious effects on the mother and fetus. Common polymorphisms in... 
high folate | NEURAL-TUBE DEFECTS | embryo | POLYMORPHISM | TANDEM MASS-SPECTROMETRY | birth defects | METHYLENETETRAHYDROFOLATE REDUCTASE DEFICIENCY | CHOLINE METABOLISM | methylenetetrahydrofolate reductase | PREGNANT CANADIAN WOMEN | NUTRITION & DIETETICS | developmental defects | MTHFD1 | S-ADENOSYLHOMOCYSTEINE | placenta | GENETIC RISK-FACTOR | LOW DIETARY-FOLATE | folic acid | CONGENITAL HEART-DEFECTS | S-Adenosylhomocysteine - metabolism | Folic Acid - pharmacology | Methylenetetrahydrofolate Dehydrogenase (NADP) - deficiency | Aminohydrolases - deficiency | Multienzyme Complexes - metabolism | Methylenetetrahydrofolate Reductase (NADPH2) - metabolism | Aminohydrolases - genetics | Multienzyme Complexes - deficiency | Methylenetetrahydrofolate Reductase (NADPH2) - genetics | Female | Embryo, Mammalian - enzymology | Methylenetetrahydrofolate Dehydrogenase (NADP) - genetics | Methylenetetrahydrofolate Dehydrogenase (NADP) - metabolism | Formate-Tetrahydrofolate Ligase - deficiency | Logistic Models | Mice, Transgenic | Placenta - abnormalities | Placenta - enzymology | Multienzyme Complexes - genetics | Pregnancy | Formate-Tetrahydrofolate Ligase - metabolism | Animals | Choline - pharmacology | Formate-Tetrahydrofolate Ligase - genetics | Aminohydrolases - metabolism | Mice | Polymorphism, Single Nucleotide | Embryonic Development - drug effects | Dietary Supplements | S-Adenosylmethionine - metabolism | Ligases | Genetic variation | Pregnancy, Complications of | Development and progression | Genetic aspects | Health aspects | Folic acid | Vitamin B | Rodents | Dietary supplements | Prenatal development | Birth defects | Embryos | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article