EUROPEAN JOURNAL OF PHARMACOLOGY, ISSN 0014-2999, 02/2014, Volume 725, pp. 70 - 78
Hydrogen sulfide (H2S) has been proposed as a novel gas-transmittter, which plays multiple physiological and pathological functions in various body systems,...
Oxidative stress | Keap 1 | ACTIVATED PROTEIN-KINASE | RAT | JNK | H2S | ENDOPLASMIC-RETICULUM STRESS | ISCHEMIA-REPERFUSION INJURY | NF-kappa B | P38 | MUCOSAL INJURY | s-Sulfhydration | PHARMACOLOGY & PHARMACY | CONTRIBUTES
Oxidative stress | Keap 1 | ACTIVATED PROTEIN-KINASE | RAT | JNK | H2S | ENDOPLASMIC-RETICULUM STRESS | ISCHEMIA-REPERFUSION INJURY | NF-kappa B | P38 | MUCOSAL INJURY | s-Sulfhydration | PHARMACOLOGY & PHARMACY | CONTRIBUTES
Journal Article
Scandinavian Journal of Gastroenterology, ISSN 0036-5521, 10/2019, Volume 54, Issue 10, pp. 1199 - 1204
Objectives: Low-dose aspirin is the standard treatment for the prevention of cardiovascular events in at-risk patients. We performed a randomized,...
gastroduodenal ulcer | Teprenone | gastric mucosal injury | low-dose aspirin
gastroduodenal ulcer | Teprenone | gastric mucosal injury | low-dose aspirin
Journal Article
BLOOD, ISSN 0006-4971, 07/2013, Volume 122, Issue 4, pp. 608 - 617
Endogenous protective pathways mitigate the overshooting of inflammation after sterile or infectious injury. Here we report that formyl peptide receptor 2...
MUCOSAL INJURY | PRIMED NEUTROPHILS | RESOLUTION | ANNEXIN-1 | HUMAN PLATELETS | MICE | RENAL ISCHEMIA/REPERFUSION INJURY | LIPID MEDIATORS | ISCHEMIA-REPERFUSION | HEMATOLOGY | ACUTE-INFLAMMATION
MUCOSAL INJURY | PRIMED NEUTROPHILS | RESOLUTION | ANNEXIN-1 | HUMAN PLATELETS | MICE | RENAL ISCHEMIA/REPERFUSION INJURY | LIPID MEDIATORS | ISCHEMIA-REPERFUSION | HEMATOLOGY | ACUTE-INFLAMMATION
Journal Article
Scandinavian Journal of Gastroenterology, ISSN 0036-5521, 02/2019, Volume 54, Issue 2, pp. 227 - 232
Background and aim: Although the fluoropyrimidines are effective chemotherapeutic agents for malignant gastrointestinal tumors, they sometimes cause enteritis...
small intestinal mucosal injury | serum DAO activity | chemotherapy | diarrhea | Fluoropyrimidine
small intestinal mucosal injury | serum DAO activity | chemotherapy | diarrhea | Fluoropyrimidine
Journal Article
International Journal of Surgical Pathology, ISSN 1066-8969, 5/2018, Volume 26, Issue 3, pp. 238 - 239
Journal Article
Cancer, ISSN 0008-543X, 2014, Volume 120, Issue 10, pp. 1453 - 1461
BACKGROUND Mucositis is a highly significant, and sometimes dose-limiting, toxicity of cancer therapy. The goal of this systematic review was to update the...
gastrointestinal | mucositis | guidelines | oral | stomatitis | Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC/ISOO) | HEAD | GASTROINTESTINAL MUCOSITIS | ISOO | CELL TRANSPLANTATION | RANDOMIZED-TRIAL | ZINC SUPPLEMENTATION | NECK-CANCER | ONCOLOGY | MUCOSAL INJURY | ORAL MUCOSITIS | DOUBLE-BLIND | LEVEL LASER THERAPY | Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC | Sucralfate - administration & dosage | Humans | Radiotherapy - adverse effects | Antineoplastic Agents - administration & dosage | Protective Agents - therapeutic use | Mucositis - prevention & control | Proctitis - prevention & control | Antineoplastic Agents - adverse effects | Anti-Inflammatory Agents - therapeutic use | Neoplasms - radiotherapy | Intercellular Signaling Peptides and Proteins - administration & dosage | Low-Level Light Therapy | Esophagitis - therapy | Analgesics - therapeutic use | Proctitis - therapy | Anti-Infective Agents - therapeutic use | Evidence-Based Medicine | Mucositis - therapy | Cytokines - administration & dosage | Esophagitis - etiology | Stomatitis - etiology | Mucositis - chemically induced | Oral Hygiene | Anti-Ulcer Agents - administration & dosage | Neoplasms - drug therapy | Phototherapy | Stomatitis - therapy | Proctitis - etiology | Mucositis - etiology | Stomatitis - chemically induced | Esophagitis - prevention & control | Radiation-Protective Agents - therapeutic use | Stomatitis - prevention & control | Amifostine - therapeutic use | Cryotherapy | Hyperbaric Oxygenation | Practice guidelines (Medicine) | Usage | Care and treatment | Mucositis | Analysis | Cancer | Index Medicus | Abridged Index Medicus | Review
gastrointestinal | mucositis | guidelines | oral | stomatitis | Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC/ISOO) | HEAD | GASTROINTESTINAL MUCOSITIS | ISOO | CELL TRANSPLANTATION | RANDOMIZED-TRIAL | ZINC SUPPLEMENTATION | NECK-CANCER | ONCOLOGY | MUCOSAL INJURY | ORAL MUCOSITIS | DOUBLE-BLIND | LEVEL LASER THERAPY | Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC | Sucralfate - administration & dosage | Humans | Radiotherapy - adverse effects | Antineoplastic Agents - administration & dosage | Protective Agents - therapeutic use | Mucositis - prevention & control | Proctitis - prevention & control | Antineoplastic Agents - adverse effects | Anti-Inflammatory Agents - therapeutic use | Neoplasms - radiotherapy | Intercellular Signaling Peptides and Proteins - administration & dosage | Low-Level Light Therapy | Esophagitis - therapy | Analgesics - therapeutic use | Proctitis - therapy | Anti-Infective Agents - therapeutic use | Evidence-Based Medicine | Mucositis - therapy | Cytokines - administration & dosage | Esophagitis - etiology | Stomatitis - etiology | Mucositis - chemically induced | Oral Hygiene | Anti-Ulcer Agents - administration & dosage | Neoplasms - drug therapy | Phototherapy | Stomatitis - therapy | Proctitis - etiology | Mucositis - etiology | Stomatitis - chemically induced | Esophagitis - prevention & control | Radiation-Protective Agents - therapeutic use | Stomatitis - prevention & control | Amifostine - therapeutic use | Cryotherapy | Hyperbaric Oxygenation | Practice guidelines (Medicine) | Usage | Care and treatment | Mucositis | Analysis | Cancer | Index Medicus | Abridged Index Medicus | Review
Journal Article
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, ISSN 0193-1857, 01/2015, Volume 308, Issue 2, pp. G63 - G75
Research in the field of ischemia-reperfusion injury continues to be plagued by the inability to translate research findings to clinically useful therapies....
mucosal injury | STEM-CELL POPULATIONS | PHYSIOLOGY | intestine | PROSTAGLANDIN-INDUCED RECOVERY | PORCINE ILEUM | XANTHINE-OXIDASE INHIBITORS | BARRIER FUNCTION | RAT SMALL-INTESTINE | ischemia | ACUTE MESENTERIC ISCHEMIA | FELINE SMALL-INTESTINE | GROWTH-FACTOR | animal model | CAT SMALL-INTESTINE | GASTROENTEROLOGY & HEPATOLOGY | reperfusion
mucosal injury | STEM-CELL POPULATIONS | PHYSIOLOGY | intestine | PROSTAGLANDIN-INDUCED RECOVERY | PORCINE ILEUM | XANTHINE-OXIDASE INHIBITORS | BARRIER FUNCTION | RAT SMALL-INTESTINE | ischemia | ACUTE MESENTERIC ISCHEMIA | FELINE SMALL-INTESTINE | GROWTH-FACTOR | animal model | CAT SMALL-INTESTINE | GASTROENTEROLOGY & HEPATOLOGY | reperfusion
Journal Article
Cancer, ISSN 0008-543X, 03/2007, Volume 109, Issue 5, pp. 820 - 831
Considerable progress in research and clinical application has been made since the original guidelines for managing mucositis in cancer patients were published...
cancer therapy | clinical practice guidelines | mucosal barrier injury | mucositis (alimentary, gastrointestinal [GI], oral) | mucositis pathogenesis | Clinical practice guidelines | Mucosal barrier injury | Cancer therapy | Mucositis (alimentary, gastrointestinal [GI], oral) | Mucositis pathogenesis | NECK-CANCER PATIENTS | GASTROINTESTINAL MUCOSITIS | COLONY-STIMULATING FACTOR | RANDOMIZED-TRIAL | SEVERE ORAL MUCOSITIS | ALIMENTARY-TRACT MUCOSITIS | ONCOLOGY | MUCOSAL INJURY | DOUBLE-BLIND | HIGH-DOSE CHEMOTHERAPY | STEM-CELL TRANSPLANTATION | Neoplasms - therapy | Antineoplastic Agents - adverse effects | Humans | Mucositis - etiology | Risk Factors | Radiotherapy - adverse effects | Mucositis - prevention & control | Prevention | Care and treatment | Gastric mucosa | Gastrointestinal diseases | Practice guidelines (Medicine) | Research | Diseases
cancer therapy | clinical practice guidelines | mucosal barrier injury | mucositis (alimentary, gastrointestinal [GI], oral) | mucositis pathogenesis | Clinical practice guidelines | Mucosal barrier injury | Cancer therapy | Mucositis (alimentary, gastrointestinal [GI], oral) | Mucositis pathogenesis | NECK-CANCER PATIENTS | GASTROINTESTINAL MUCOSITIS | COLONY-STIMULATING FACTOR | RANDOMIZED-TRIAL | SEVERE ORAL MUCOSITIS | ALIMENTARY-TRACT MUCOSITIS | ONCOLOGY | MUCOSAL INJURY | DOUBLE-BLIND | HIGH-DOSE CHEMOTHERAPY | STEM-CELL TRANSPLANTATION | Neoplasms - therapy | Antineoplastic Agents - adverse effects | Humans | Mucositis - etiology | Risk Factors | Radiotherapy - adverse effects | Mucositis - prevention & control | Prevention | Care and treatment | Gastric mucosa | Gastrointestinal diseases | Practice guidelines (Medicine) | Research | Diseases
Journal Article
Pharmacological Research, ISSN 1043-6618, 05/2015, Volume 95-96, pp. 138 - 158
Herbal medicine has attracted great attention in the recent years and is increasingly used as alternatives to chemical drugs. Several lines of evidence support...
Anti-oxidants | Anti-cancer | Review | Black cumin | Nigella sativa | Thymoquinone | NIGELLA-SATIVA OIL | DOXORUBICIN-INDUCED CARDIOTOXICITY | COLLAGEN-INDUCED ARTHRITIS | GASTRIC-MUCOSAL INJURY | NITRIC-OXIDE SYNTHASE | CHRONIC TOLUENE EXPOSURE | ACTIVE PRINCIPLE | IN-VITRO | INDUCED OXIDATIVE STRESS | PHARMACOLOGY & PHARMACY | NF-KAPPA-B | Benzoquinones - pharmacology | Animals | Humans | Nigella sativa - chemistry | Benzoquinones - isolation & purification | Seeds - chemistry | Benzoquinones - therapeutic use | Plant Oils - chemistry | Benzoquinones - adverse effects | Health aspects | Cells
Anti-oxidants | Anti-cancer | Review | Black cumin | Nigella sativa | Thymoquinone | NIGELLA-SATIVA OIL | DOXORUBICIN-INDUCED CARDIOTOXICITY | COLLAGEN-INDUCED ARTHRITIS | GASTRIC-MUCOSAL INJURY | NITRIC-OXIDE SYNTHASE | CHRONIC TOLUENE EXPOSURE | ACTIVE PRINCIPLE | IN-VITRO | INDUCED OXIDATIVE STRESS | PHARMACOLOGY & PHARMACY | NF-KAPPA-B | Benzoquinones - pharmacology | Animals | Humans | Nigella sativa - chemistry | Benzoquinones - isolation & purification | Seeds - chemistry | Benzoquinones - therapeutic use | Plant Oils - chemistry | Benzoquinones - adverse effects | Health aspects | Cells
Journal Article
Cell Metabolism, ISSN 1550-4131, 03/2015, Volume 21, Issue 3, pp. 369 - 378
Bariatric surgical procedures such as vertical sleeve gastrectomy (VSG) and Roux-en-Y gastric bypass (RYGB) are the most potent treatments available to produce...
VERTICAL SLEEVE GASTRECTOMY | VAGAL INNERVATION | GLUCAGON-LIKE PEPTIDE-1 | GLUCOSE-METABOLISM | INTESTINAL MUCOSAL INJURY | SERUM BILE-ACIDS | Y GASTRIC BYPASS | INSULIN-SECRETION | ENDOCRINOLOGY & METABOLISM | WEIGHT-LOSS | ILEAL INTERPOSITION SURGERY | CELL BIOLOGY | Obesity - surgery | Animals | Diabetes Mellitus - physiopathology | Gastrointestinal Tract - physiology | Humans | Adaptation, Physiological - physiology | Obesity - physiopathology | Body Weight - physiology | Bariatric Surgery - methods | Diabetes Mellitus - surgery | Food | Obesity | Surgery | Analysis | Gastrointestinal system | Diabetes | Glucose | Health aspects | Dextrose | Deoxycholic acid
VERTICAL SLEEVE GASTRECTOMY | VAGAL INNERVATION | GLUCAGON-LIKE PEPTIDE-1 | GLUCOSE-METABOLISM | INTESTINAL MUCOSAL INJURY | SERUM BILE-ACIDS | Y GASTRIC BYPASS | INSULIN-SECRETION | ENDOCRINOLOGY & METABOLISM | WEIGHT-LOSS | ILEAL INTERPOSITION SURGERY | CELL BIOLOGY | Obesity - surgery | Animals | Diabetes Mellitus - physiopathology | Gastrointestinal Tract - physiology | Humans | Adaptation, Physiological - physiology | Obesity - physiopathology | Body Weight - physiology | Bariatric Surgery - methods | Diabetes Mellitus - surgery | Food | Obesity | Surgery | Analysis | Gastrointestinal system | Diabetes | Glucose | Health aspects | Dextrose | Deoxycholic acid
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 03/2015, Volume 125, Issue 3, pp. 1215 - 1227
Epithelial restitution is an essential process that is required to repair barrier function at mucosal surfaces following injury. Prolonged breaches in...
MEDICINE, RESEARCH & EXPERIMENTAL | MUCOSAL INJURY | INFLAMMATION | FORMYL PEPTIDE RECEPTOR | MULTIVESICULAR ENDOSOMES | ULCERATIVE-COLITIS | IN-VIVO | RESOLUTION | FLOW-CYTOMETRY | PRORESOLVING LIPID MEDIATORS | DISTINCT POPULATIONS | Cell Line | Intestinal Mucosa - physiopathology | Annexin A1 - physiology | Annexin A1 - administration & dosage | Humans | Wound Healing | Intestinal Mucosa - drug effects | Peptides - administration & dosage | Mice, Knockout | Nanoparticles | Animals | Colitis - physiopathology | Colitis - blood | Exosomes - physiology | Anti-Inflammatory Agents - administration & dosage | Medical research | Wound healing | Physiological aspects | Medicine, Experimental | Research | Annexins | Studies | Proteins | Inflammatory bowel disease | Plasma | Peptides | Microscopy | Biopsy | Rodents
MEDICINE, RESEARCH & EXPERIMENTAL | MUCOSAL INJURY | INFLAMMATION | FORMYL PEPTIDE RECEPTOR | MULTIVESICULAR ENDOSOMES | ULCERATIVE-COLITIS | IN-VIVO | RESOLUTION | FLOW-CYTOMETRY | PRORESOLVING LIPID MEDIATORS | DISTINCT POPULATIONS | Cell Line | Intestinal Mucosa - physiopathology | Annexin A1 - physiology | Annexin A1 - administration & dosage | Humans | Wound Healing | Intestinal Mucosa - drug effects | Peptides - administration & dosage | Mice, Knockout | Nanoparticles | Animals | Colitis - physiopathology | Colitis - blood | Exosomes - physiology | Anti-Inflammatory Agents - administration & dosage | Medical research | Wound healing | Physiological aspects | Medicine, Experimental | Research | Annexins | Studies | Proteins | Inflammatory bowel disease | Plasma | Peptides | Microscopy | Biopsy | Rodents
Journal Article
Medicine (United States), ISSN 0025-7974, 03/2018, Volume 97, Issue 11
Journal Article
SCIENCE TRANSLATIONAL MEDICINE, ISSN 1946-6234, 10/2019, Volume 11, Issue 516, p. eaat7455
Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most important causes of peptic ulcer disease in high-income countries. Proton pump inhibitors are...
MEDICINE, RESEARCH & EXPERIMENTAL | CYCLOOXYGENASE-2 | ANGIOGENESIS | SECRETOME | ROLES | GASTRIC-MUCOSAL INJURY | REGENERATION | INDOMETHACIN | MECHANISMS | GROWTH-FACTOR | INDUCTION | CELL BIOLOGY
MEDICINE, RESEARCH & EXPERIMENTAL | CYCLOOXYGENASE-2 | ANGIOGENESIS | SECRETOME | ROLES | GASTRIC-MUCOSAL INJURY | REGENERATION | INDOMETHACIN | MECHANISMS | GROWTH-FACTOR | INDUCTION | CELL BIOLOGY
Journal Article
Annals of Oncology, ISSN 0923-7534, 2011, Volume 22, Issue suppl_6, pp. vi78 - vi84
BREAST-CANCER | ALIMENTARY-TRACT MUCOSITIS | CANCER-PATIENTS | RISK-FACTORS | ONCOLOGY | MUCOSAL INJURY | COLORECTAL-CANCER | RANDOMIZED-TRIAL | PHASE-II | ADVANCED HEAD | NECK-CANCER | Stomatitis - therapy | Humans | Mucositis - etiology | Gastrointestinal Diseases - etiology | Gastrointestinal Diseases - therapy | Mucositis - therapy | Stomatitis - etiology | Supportive Care
Journal Article
CLINICAL INFECTIOUS DISEASES, ISSN 1058-4838, 07/2019, Volume 69, Issue 2, pp. 268 - 277
Background. Gut dysbiosis has been suggested as a major risk factor for the development of late-onset sepsis (LOS), a main cause of mortality and morbidity in...
INFECTIOUS DISEASES | BACTERIA | gut | GASTROINTESTINAL-TRACT | RISK | MICROBIOLOGY | preterm infant | COLONIZATION | IMMUNOLOGY | microbiome | bacterial metabolism | BIRTH-WEIGHT INFANTS | COMMUNITY | DIET | MUCOSAL INJURY | CHAIN FATTY-ACIDS | BLOOD-STREAM INFECTIONS | dysbiosis
INFECTIOUS DISEASES | BACTERIA | gut | GASTROINTESTINAL-TRACT | RISK | MICROBIOLOGY | preterm infant | COLONIZATION | IMMUNOLOGY | microbiome | bacterial metabolism | BIRTH-WEIGHT INFANTS | COMMUNITY | DIET | MUCOSAL INJURY | CHAIN FATTY-ACIDS | BLOOD-STREAM INFECTIONS | dysbiosis
Journal Article