X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (18450) 18450
Book Chapter (114) 114
Dissertation (83) 83
Newspaper Article (22) 22
Book / eBook (10) 10
Publication (9) 9
Conference Proceeding (7) 7
Government Document (5) 5
Book Review (2) 2
Magazine Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (9648) 9648
multidrug-resistance (6688) 6688
p-glycoprotein (5927) 5927
multidrug resistance (5726) 5726
animals (5347) 5347
pharmacology & pharmacy (5239) 5239
drug resistance (4205) 4205
cancer (3096) 3096
expression (3054) 3054
microbiology (2858) 2858
oncology (2796) 2796
female (2644) 2644
biochemistry & molecular biology (2541) 2541
chemotherapy (2401) 2401
male (2377) 2377
proteins (2283) 2283
drug resistance in microorganisms (2243) 2243
cell line, tumor (2015) 2015
mice (1980) 1980
drug-resistance (1908) 1908
atp-binding cassette, sub-family b, member 1 - metabolism (1861) 1861
efflux (1806) 1806
in-vitro (1791) 1791
research (1724) 1724
analysis (1691) 1691
gene expression (1651) 1651
escherichia-coli (1629) 1629
multidrug resistance-associated proteins - metabolism (1614) 1614
anti-bacterial agents - pharmacology (1508) 1508
apoptosis (1489) 1489
drug resistance, neoplasm (1489) 1489
antibiotics (1485) 1485
atp-binding cassette transporters - metabolism (1434) 1434
antineoplastic agents - pharmacology (1389) 1389
microbial sensitivity tests (1333) 1333
drug resistance, multiple (1330) 1330
genes (1321) 1321
transporter (1310) 1310
multidrug resistance-associated proteins - genetics (1306) 1306
bacteria (1303) 1303
drugs (1247) 1247
mutation (1245) 1245
gene (1241) 1241
cells (1220) 1220
cell biology (1209) 1209
doxorubicin (1203) 1203
genetic aspects (1190) 1190
atp-binding cassette transporters - genetics (1174) 1174
atp-binding cassette, sub-family b, member 1 - genetics (1136) 1136
infectious diseases (1133) 1133
biological transport (1104) 1104
resistance (1080) 1080
rats (1070) 1070
health aspects (1058) 1058
multidisciplinary sciences (1029) 1029
adult (1022) 1022
mechanisms (1012) 1012
abc transporters (1008) 1008
chemistry, medicinal (994) 994
medicine (989) 989
pharmacokinetics (979) 979
research article (967) 967
breast cancer (959) 959
transport (958) 958
middle aged (948) 948
protein (937) 937
chemistry, multidisciplinary (924) 924
drug resistance, neoplasm - drug effects (915) 915
tumors (906) 906
inhibition (900) 900
physiological aspects (900) 900
cancer therapies (885) 885
doxorubicin - pharmacology (849) 849
cytotoxicity (846) 846
bacterial proteins - genetics (843) 843
glycoproteins (840) 840
dose-response relationship, drug (837) 837
pseudomonas-aeruginosa (837) 837
drug therapy (835) 835
cell line (824) 824
tumor cells, cultured (816) 816
membrane transport proteins - metabolism (811) 811
flow cytometry (789) 789
gram-negative bacteria (768) 768
cell survival - drug effects (765) 765
gene-expression (762) 762
life sciences (755) 755
molecular sequence data (753) 753
antibiotic resistance (750) 750
abc transporter (743) 743
biotechnology & applied microbiology (739) 739
care and treatment (737) 737
medicine, research & experimental (731) 731
antimicrobial resistance (717) 717
breast-cancer (713) 713
atp binding cassette transporter, sub-family g, member 2 (710) 710
bacterial proteins - metabolism (705) 705
identification (703) 703
toxicology (699) 699
antibiotic-resistance (691) 691
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (18550) 18550
Japanese (172) 172
French (40) 40
Chinese (38) 38
Polish (25) 25
German (19) 19
Spanish (15) 15
Turkish (9) 9
Russian (7) 7
Korean (5) 5
Czech (4) 4
Hungarian (4) 4
Portuguese (4) 4
Slovak (2) 2
Arabic (1) 1
Dutch (1) 1
Lithuanian (1) 1
Swedish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Journal Article
FEMS Microbiology Reviews, ISSN 1574-6976, 2012, Volume 36, Issue 2, pp. 340 - 363
...’ and consequently increases the frequency of therapeutic failure. In MDR bacteria, the overexpression of efflux pumps that expel structurally unrelated drugs contributes... 
structure–function relationship | RND family drug transporters | antibiotic resistance | outer membrane permeability | MDR bacteria | bacterial efflux pump | Outer membrane permeability | Bacterial efflux pump | Structure-function relationship | Antibiotic resistance | URINARY-TRACT-INFECTIONS | structure-function relationship | LARGE PERIPLASMIC LOOPS | OUTER-MEMBRANE PERMEABILITY | MICROBIOLOGY | SITE-DIRECTED MUTAGENESIS | ESCHERICHIA-COLI STRAINS | ANTIMICROBIAL DRUG SUSCEPTIBILITY | PSEUDOMONAS-AERUGINOSA PORIN | CYSTIC-FIBROSIS PATIENTS | KLEBSIELLA-PNEUMONIAE STRAINS | BETA-LACTAM ANTIBIOTICS | Humans | Bacterial Proteins - genetics | Anti-Bacterial Agents - metabolism | Gram-Negative Bacterial Infections - drug therapy | Gram-Negative Bacteria - metabolism | Gram-Negative Bacterial Infections - microbiology | Gram-Negative Bacteria - drug effects | Animals | Membrane Transport Proteins - genetics | Drug Resistance, Multiple, Bacterial | Bacterial Proteins - metabolism | Membrane Transport Proteins - metabolism | Anti-Bacterial Agents - pharmacology | Gram-Negative Bacteria - genetics | Translocation | Efflux | Antibiotics | Pumps | Multidrug resistance | Bacteria | Gram-negative bacteria | Parameter identification | Drug resistance | Antibacterial agents | Transporter | Data processing | Kinetics | Drug development | selectivity
Journal Article