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Pharmacology & therapeutics (Oxford), ISSN 0163-7258, 08/2005, Volume 107, Issue 2, pp. 222 - 239
Validation | Therapy | RNAi | siRNA | Disease | shRNA | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | RNA, Small Interfering - genetics | RNA Interference - drug effects | Gene Silencing - drug effects | Humans | Respiratory Tract Diseases - drug therapy | Neoplasms - drug therapy | Animals | Communicable Diseases - drug therapy | Neoplasms - genetics | RNA, Small Interfering - therapeutic use | Drug Design | RNA Interference - physiology | RNA, Small Interfering - administration & dosage | Gene Silencing - physiology | Genetic research | Genetic engineering | RNA | Gene expression | Analysis | Index Medicus | LNA, locked nucleic acid | HBV, hepatitis B virus | PEG, polyethylene glycol | SCID, severe combined immunodeficiency | RNAi, RNA interference | TGFβ, transforming growth factor β | COPD, chronic obstructive pulmonary disease | dsRNA, double-stranded RNA | ABCA1, ATP-binding cassette, subfamily A, member 1 | AAV, adeno-associated virus | MDR, multidrug-resistance protein | B-RAF, murine sarcoma viral (v-raf) oncogene homolog B1 oncogene | smad 1, mothers against decapentaplegic homolog 1 | Bcl-2, B-cell chronic lymphocytic leukemia | NF-κB, Nuclear factor-kappaB | LoxP, locus χ of crossover P1 | HIV, human immunodeficiency virus | ERK, extracellular signal regulated protein kinase | lymphoma 2 | VEGF, vascular endothelial growth factor | SARS, severe acute respiratory syndrome | CXCR4, chemokine (C–X–C motif), receptor 4 | Fas, tumour necrosis factor receptor superfamily, member 6 | EGFR, epidermal growth factor receptor | miRNA, microRNAs | EC, endothelial cell | PKR, dsRNA-dependent protein kinase | LPS, lipopolysaccharide | shRNA, short hairpin RNA | BMP4, bone morphogenetic protein 4 | Rnase III, ribonuclease III | MAPK, mitogen-activated protein kinase | KC, keratinocyte-derived chemokine | CCR5, chemokine (C–C motif) receptor 5 | HCV, hepatitis C virus | Cre, causes recombination | BCR-ABL, breakpoint cluster region-protooncogene tyrosine-protein kinase ABL1 fusion protein | smad 7, mothers against decapentaplegic homolog 7 | EpCAM, tumour-associated calcium signal transducer 1 | TLR3, toll-like receptor 3 | S1P, sphingosine 1-phosphate | HMG-CoA, beta-hydroxy-beta-methylglutaryl coenzyme A | RISC, RNA-induced silencing complex | TNFα, tumour necrosis factor α | CML, chronic myelogenous leukemia | bp, base pairs | TGFα, transforming growth factor α | IFN, interferon | CD8, T-lymphocyte differentiation antigen T8 | K-Ras, c-Kirsten-ras protein | RdDM, RNA-directed DNA methylation | siRNA, small interfering RNA | PEI, polyethyleneimine | RasGAP, Ras GTPase-activating protein | MIP2, macrophage inflammatory protein-2 | LacZ, β-galactosidase α-peptide | Leu-2 | RSV, respiratory syncytial virus
Journal Article