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Current Opinion in Structural Biology, ISSN 0959-440X, 2008, Volume 18, Issue 4, pp. 459 - 465
Journal Article
Journal Article
FRONTIERS IN MICROBIOLOGY, ISSN 1664-302X, 07/2019, Volume 10, p. 1445
ATP-binding cassette (ABC) superfamily members have a key role as nutrient importers and exporters in bacteria. However, their role as drug exporters in... 
Candida auris | multidrug resistance | GLABRATA | MECHANISM | MEMBRANE | drug efflux pumps | MICROBIOLOGY | YEAST | fluconazole | ABC proteins | INVENTORY | CLONING | ALBICANS | PROTEINS | STEROL UPTAKE | YCF1P | Gene expression | Adenosine triphosphate | Research
Journal Article
The Plant Cell, ISSN 1040-4651, 12/2007, Volume 19, Issue 12, pp. 3930 - 3943
ATP binding cassette (ABC) transporters transport diverse substrates across membranes in various organisms. However, plant ABC transporters have only been... 
ATP binding cassette transporters | Yeasts | Hair cells | Epidermal cells | HeLa cells | Auxins | Root hairs | Cell membranes | Plants | Plant cells | BIOCHEMISTRY & MOLECULAR BIOLOGY | MECHANISMS | PIN PROTEINS | P-GLYCOPROTEIN | PLANT SCIENCES | CELL BIOLOGY | PATHWAY | GROWTH | TWISTED DWARF1 | MULTIDRUG-RESISTANCE | EXPRESSION | PLANT ABC TRANSPORTERS | GNOM ARF-GEF | Plant Roots - genetics | Brefeldin A - pharmacology | Arabidopsis Proteins - metabolism | ATP-Binding Cassette Transporters - genetics | Plants, Genetically Modified | ATP-Binding Cassette Transporters - metabolism | ATP Binding Cassette Transporter, Subfamily B - genetics | Biological Transport - drug effects | Arabidopsis Proteins - genetics | Arabidopsis - drug effects | Plant Roots - metabolism | Indoleacetic Acids - metabolism | Tobacco - metabolism | Cells, Cultured | Plant Roots - cytology | Reverse Transcriptase Polymerase Chain Reaction | ATP Binding Cassette Transporter, Subfamily B - metabolism | Arabidopsis - metabolism | Tobacco - cytology | Arabidopsis - genetics | Microscopy, Confocal | Gene Expression Regulation, Plant - drug effects | Indoleacetic Acids - pharmacology | Tobacco - genetics | Plant Growth Regulators - metabolism | Plant Growth Regulators - pharmacology | Staurosporine - pharmacology | Auxin | Carrier proteins | Arabidopsis | Physiological aspects | Glycoproteins | Chemical properties | Adenosine triphosphate
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 2009, Volume 78, Issue 2, pp. 153 - 161
Journal Article
Cell, ISSN 0092-8674, 03/2017, Volume 168, Issue 6, pp. 951 - 953
The subfamily C ATP-binding cassette (ABCC) transporters mediate multidrug resistance and ion conductance regulation. Recent atomic or near-atomic resolution... 
BINDING | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | P-GLYCOPROTEIN | CELL BIOLOGY | ATP-Binding Cassette Transporters - chemistry | Membrane Transport Proteins | Multidrug Resistance-Associated Proteins | Drug resistance in microorganisms | Atoms
Journal Article
2009, 1. Aufl., Wiley series in drug discovery and development, ISBN 9780470227343, xiii, 459
A comprehensive review of the most current scientific research on ABC transporters and multidrug resistanceATP-binding cassette transporter genes (ABC... 
MEDICAL / Pharmacology | Drug resistance in cancer cells | ATP-binding cassette transporters
Book
Neuroscience, ISSN 0306-4522, 2008, Volume 155, Issue 2, pp. 423 - 438
Abstract Nutrient transporters and ABC efflux pumps at the blood–brain barrier are major determinants of drug penetration into the brain. Immunohistochemical... 
Neurology | abluminal | cerebral microvessels | luminal | ABC transporter | choroid plexus | NEUROSCIENCES | P-GLYCOPROTEIN ABCB1 | MICROVESSEL ENDOTHELIUM | AMINO-ACID TRANSPORTER | ABLUMINAL MEMBRANE | GLUCOSE-TRANSPORTER | RESISTANCE-ASSOCIATED PROTEIN-1 | CENTRAL-NERVOUS-SYSTEM | CAPILLARY ENDOTHELIAL-CELLS | CHOROID-PLEXUS | MULTIDRUG TRANSPORTERS | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | Ependyma - blood supply | Cerebrovascular Circulation - physiology | Large Neutral Amino Acid-Transporter 1 - metabolism | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Choroid Plexus - metabolism | Glucose Transporter Type 1 - metabolism | Male | Gene Expression Profiling | Choroid Plexus - ultrastructure | Blood-Brain Barrier - ultrastructure | Microcirculation - physiology | Choroid Plexus - blood supply | Monocarboxylic Acid Transporters - metabolism | Transfection | ATP-Binding Cassette Transporters - genetics | Membrane Transport Proteins - genetics | ATP-Binding Cassette Transporters - metabolism | Blood-Brain Barrier - physiology | Membrane Transport Proteins - metabolism | Multidrug Resistance-Associated Proteins - genetics | Cell Line | Biotinylation | Rats | Ependyma - metabolism | Large Neutral Amino Acid-Transporter 1 - genetics | Kidney - cytology | Rats, Sprague-Dawley | Blotting, Western | Symporters - metabolism | Animals | Glucose Transporter Type 1 - genetics | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | Symporters - genetics | Microcirculation - ultrastructure | Monocarboxylic Acid Transporters - genetics | Multidrug Resistance-Associated Proteins - metabolism | Ependyma - ultrastructure | Phosphates | Glucose metabolism | Brain | Fluorescein | Biotin | Glucose | Drug resistance | Intermediate filament proteins | Dextrose | Protein binding
Journal Article
Advanced Drug Delivery Reviews, ISSN 0169-409X, 2003, Volume 55, Issue 1, pp. 151 - 164
Journal Article
Acta Pharmaceutica Sinica B, ISSN 2211-3835, 05/2017, Volume 7, Issue 3, pp. 260 - 280
Oral drug absorption is a process influenced by the physicochemical and biopharmaceutical properties of the drug and its inter-relationship with the... 
Formulation strategies | Factors affecting absorption | BCS | Permeability | Solubility | FORMULATION DEVELOPMENT | Formulations strategies | SOLID DISPERSION | BIORELEVANT DISSOLUTION MEDIA | POLYMERIC MICELLES | DRUG-DELIVERY-SYSTEMS | EQUILIBRIUM SOLUBILITY | MESOPOROUS SILICON MICROPARTICLES | NANOSTRUCTURED LIPID CARRIERS | ORAL BIOAVAILABILITY | PHARMACOLOGY & PHARMACY | IN-VIVO EVALUATION | AZT, azidothymidine | PEG, polyethylene glycol | P-gp, P-glycoprotein | MCT, monocarboxylate transporter | VDAD, volume to dissolve applied dose | OMM, ordered mesoporous material | vit. E TPGS, vitamin E tocopherol polyethylene glycol succinate | SLC, solute carrier | ABC, ATP-binding cassette | GRAS, generally recognized as safe | BE, bioavailability | SPIP, single pass intestinal perfusion | OAT, organic anion transporter | NLC, nanostructured lipid carrier | GIS, gastrointestinal simulator | IR, immediate release | PAMPA, parallel artificial membrane permeability assay | SGLT, sodium dependent secondary active transporter | AP, absorption potential | SDS, sodium dodecyl sulphate | CD, cyclodextrin | SIF, simulated intestinal fluid | bioequivalence | FDA, U.S. Food and Drug Administration | RFC, reduced folate transporter | BSP, bromosulfophthalein | Psi, porous silicon | FeSSIF, fed state simulated intestinal fluid | FaSSIF, fasted state simulated intestinal fluid | Peff, effective permeability | EMEA, European Medicines Agency | OCTN, organic cationic | CNT, concentrative nucleoside transporter | PAH, p-aminohippurate | carnitine transporter | OATP, organic anion transporting polypeptide | D:S, dose:solubility | BCRP, breast cancer resistance protein | OCT, organic cationic transporter | MPP, 1-methyl-4-phenylpyridinium | MRP, multidrug resistance associated protein | SLCO, solute carrier organic anion | SMVT, sodium dependent multivitamin transporter | ISBT, sodium dependent bile salt transporter | TEOS, tetraethylortho silicate | Review | CNT, Na+-dependent concentrative transporter | UWL, unstirred water layer | E217G, estradiol 17β-glucuronide | PMAT, plasma membrane monoamine transport | IDR, intrinsic dissolution rate | PVDF, polyvinylidene difluoride | SVCT, sodium-dependent vitamin C transporter | HPC-SL, LBDDS, lipid based drug delivery system | WHO, World Health Organization | ATP, adenosine triphosphate | BCS, biopharmaceutical classification system | CYP, cytochrome P450 | HIV, human immunodeficiency disease | FIP, International Pharmaceutical Federation | GLUT, sodium-independent facilitated diffusion transporter | PSA, polar surface area | NTCP, sodium-dependent taurocholate co-transporting polypeptide | ENT, equilibrative nucleoside transporter | GITA, gastrointestinal transit and absorption | HUGO, Human Genome Organization | PGA, polyglycolic acid | NME, new molecular entity | API, active pharmaceutical ingredient | PLA, poly(lactic acid) | BDDS, biopharmaceutical drug disposition system | GIT, gastrointestinal tract | Papp, apparent permeability | PLGA, poly-d,l-lactide-co-glycoside | PEPT, peptide transporter | pMMA, polymethyl methacrylate | SUPAC, scale-up and post approval changes | CDER, Centre for Drug Evaluation and Research | PEI, polyethyleneimine | FATP, fatty acid transporter protein | ICH, International Council of Harmonization | SLN, solid lipid nanoparticles
Journal Article