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PLoS Pathogens, ISSN 1553-7366, 10/2012, Volume 8, Issue 10, p. e1002982
Plasmodium falciparum malaria is responsible for nearly one million annual deaths worldwide. Because of the difficulty in monitoring the pathogenesis of... 
INTERCELLULAR-ADHESION MOLECULE-1 | SEVERE FALCIPARUM-MALARIA | PARASITE SEQUESTRATION | MICROBIOLOGY | VASCULAR-PERMEABILITY | PLASMODIUM-BERGHEI INFECTION | TUMOR-NECROSIS-FACTOR | MURINE MALARIA | VIROLOGY | IN-VIVO | ENDOTHELIAL CELL-INTERACTIONS | CENTRAL-NERVOUS-SYSTEM | PARASITOLOGY | Malaria, Cerebral - pathology | Blood-Brain Barrier - physiopathology | Lymphocyte Function-Associated Antigen-1 - metabolism | Mice, Inbred CBA | Parasitemia | Plasmodium berghei - pathogenicity | Cerebral Hemorrhage - etiology | Disease Models, Animal | Lipopolysaccharide Receptors - biosynthesis | Propylene Glycols - pharmacology | Blood-Brain Barrier - immunology | Cerebral Hemorrhage - drug therapy | Fingolimod Hydrochloride | Pyrimidines - pharmacology | Imatinib Mesylate | Piperazines - pharmacology | Sphingosine - pharmacology | Blood-Brain Barrier - pathology | Plasmodium yoelii - pathogenicity | Sphingosine - analogs & derivatives | Animals | Malaria, Cerebral - drug therapy | Plasmodium falciparum - pathogenicity | Mice | Mice, Inbred BALB C | Benzamides | Neuroimmunomodulation | Immunology | Blood-brain barrier | Malaria | Cerebrum | Physiological aspects | Development and progression | Research | Virulence (Microbiology) | Health aspects | Coma | Pediatrics | Pathogenesis | Mortality | Time series | Parasites | Blood | Endothelium | Medicine | Pathology | Blood platelets | Fatalities | Arrests
Journal Article
PLoS Pathogens, ISSN 1553-7366, 12/2014, Volume 10, Issue 12, p. e1004528
Cerebral malaria claims the lives of over 600,000 African children every year. To better understand the pathogenesis of this devastating disease, we compared... 
INTERCELLULAR-ADHESION MOLECULE-1 | MICROVASCULAR ENDOTHELIAL-CELLS | MICROBIOLOGY | WEIBEL-PALADE BODY | VON-WILLEBRAND-FACTOR | CD8(+) T-CELLS | TUMOR-NECROSIS-FACTOR | PLASMODIUM-BERGHEI INFECTION | MURINE MALARIA | VIROLOGY | NITRIC-OXIDE | INTRACRANIAL-PRESSURE | PARASITOLOGY | Malaria, Cerebral - pathology | Plasmodium berghei - immunology | CD8-Positive T-Lymphocytes - pathology | Humans | Cerebral Cortex - pathology | Immunosuppressive Agents - pharmacology | Macrophages - immunology | Disease Models, Animal | Neutrophils - pathology | Propylene Glycols - pharmacology | Blood-Brain Barrier - immunology | Cerebral Cortex - parasitology | Macrophages - pathology | Intercellular Adhesion Molecule-1 - immunology | Malaria, Cerebral - immunology | Neutrophils - immunology | Fingolimod Hydrochloride | Plasmodium yoelii - immunology | Sphingosine - pharmacology | Blood-Brain Barrier - pathology | Sphingosine - analogs & derivatives | Animals | Cerebral Cortex - immunology | Malaria, Cerebral - drug therapy | Occludin - immunology | Zonula Occludens-1 Protein - immunology | Claudin-5 - immunology | Mice | CD8-Positive T-Lymphocytes - immunology | Microbiological research | Brain research | Malaria | Blood-brain barrier | Physiological aspects | Hemodynamics | Research | Health aspects | Brain diseases | Leucocytes | Mortality | Rodents
Journal Article
Journal Article
Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2013, Volume 982, pp. 315 - 324
Cerebral malaria (CM) is still responsible for unacceptable death rate, while new antimalarial drugs were recently developed. CM pathophysiology shares... 
Cerebral malaria | Neuroprotection | Neuronal apoptosis | Erythropoietin | Endothelial apoptosis | Epo-biosimilars | CEPO | Murine model | Animals | Apoptosis - drug effects | Erythropoietin - therapeutic use | Malaria, Cerebral - drug therapy | Female | Mice | Malaria, Cerebral - metabolism | Blood-Brain Barrier - metabolism
Journal Article
MALARIA JOURNAL, ISSN 1475-2875, 04/2016, Volume 15
Background: Cerebral malaria (CM) is a life-threatening disease, caused mainly by Plasmodium falciparum in humans. In adults only 1-2 % of P.... 
Cerebral malaria | Metabolomics | INFECTIOUS DISEASES | FALCIPARUM | Prediction | OPLS-DA | Lipids | COGNITIVE IMPAIRMENT | FATTY-ACIDS | MECHANISMS | TROPICAL MEDICINE | PATHOGENESIS | SEQUESTRATION | NMR | PLASMODIUM-BERGHEI ANKA | SPECTROSCOPY | MICE | MURINE MODELS | PARASITOLOGY
Journal Article
INTERNATIONAL IMMUNOPHARMACOLOGY, ISSN 1567-5769, 02/2015, Volume 24, Issue 2, pp. 400 - 407
A breakdown of the brain-blood barrier (BBB) due to endothelial dysfunction is a primary feature of cerebral malaria (CM). Lipoxins (LX) are specialized... 
Malaria | Lipoxin | ACUTE LUNG INJURY | IMMUNOLOGY | BLOOD-BRAIN-BARRIER | ASPIRIN | IL-12 PRODUCTION | IN-VITRO | Endothelial dysfunction | PHARMACOLOGY & PHARMACY | MICE | HEME OXYGENASE-1 | MURINE MODELS | UP-REGULATION | Brain-blood barrier breakdown | T-CELLS
Journal Article
Journal Article