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PLoS Pathogens, ISSN 1553-7366, 01/2012, Volume 8, Issue 1, p. e1002490
In schistosomiasis patients, parasite eggs trapped in hepatic sinusoids become foci for CD4(+) T cell-orchestrated granulomatous cellular infiltrates. Since... 
MICROBIOLOGY | MURINE SCHISTOSOMIASIS | MACROPHAGE ACTIVATION | HEPATIC-FIBROSIS | VASCULAR-DISEASE | PLASMA-CELLS | INFECTED MICE | VIROLOGY | IMMUNE-RESPONSES | TNF-ALPHA | DIFFERENTIATION | EXPRESSION | PARASITOLOGY | Schistosomiasis mansoni - genetics | Liver Cirrhosis - immunology | Liver - pathology | Lung Diseases, Parasitic - parasitology | Lung Diseases, Parasitic - immunology | Schistosomiasis mansoni - immunology | Lung Diseases, Parasitic - pathology | Antibodies, Helminth - immunology | CD4-Positive T-Lymphocytes - pathology | Plasma Cells - pathology | CD4-Positive T-Lymphocytes - immunology | Liver - immunology | Antibodies, Helminth - genetics | Immunoglobulin G - immunology | Liver Cirrhosis - metabolism | Interleukin-10 - metabolism | Plasma Cells - metabolism | Antibodies, Helminth - metabolism | Lung Diseases, Parasitic - metabolism | Liver Cirrhosis - genetics | Receptors, Interleukin-10 - immunology | Schistosoma mansoni | Liver - metabolism | CD4-Positive T-Lymphocytes - metabolism | Mice, Knockout | Schistosomiasis mansoni - metabolism | Receptors, Interleukin-10 - metabolism | Animals | Immunoglobulin G - genetics | Liver Cirrhosis - parasitology | Interleukin-10 - genetics | Receptors, Interleukin-10 - antagonists & inhibitors | Mice | Mice, Inbred BALB C | Liver - parasitology | Schistosomiasis mansoni - pathology | Chronic Disease | Interleukin-10 - immunology | Lung Diseases, Parasitic - genetics | Immunoglobulin G - metabolism | Plasma Cells - immunology | Receptors, Interleukin-10 - genetics | Schistosomiasis | Immune response | Lung diseases | Physiological aspects | Host-parasite relationships | Development and progression | Research | Health aspects | Liver | Mortality | Chronic illnesses | Immune system
Journal Article
Journal Article
Immunobiology, ISSN 0171-2985, 2007, Volume 212, Issue 8, pp. 603 - 612
Abstract Vasoactive intestinal peptide (VIP) exerts a broad range of biologic actions that may include modulation of hepatic granuloma formation. This study... 
Allergy and Immunology | Advanced Basic Science | Cytokine serum levels | Liver pathology | Vasoactive intestinal peptide | Murine schistosomiasis mansoni | Hepatic granuloma formation | liver pathology | hepatic granuloma formation | CELLS | cytokine serum levels | MESSENGER-RNA EXPRESSION | IMMUNOLOGY | HEPATIC-FIBROSIS | CUTTING EDGE | vasoactive intestinal peptide | IN-VITRO | GRANULOMA-FORMATION | TH2 CYTOKINES | MICE | VIP | murine schistosomiasis mansoni | T-LYMPHOCYTES | Liver - pathology | Liver - enzymology | Schistosomiasis mansoni - immunology | Interleukin-10 - blood | Liver Diseases, Parasitic - immunology | Male | Liver Extracts - metabolism | Schistosomiasis mansoni - drug therapy | Interleukin-12 - blood | Liver - immunology | Liver Diseases, Parasitic - drug therapy | Liver Diseases, Parasitic - metabolism | Vasoactive Intestinal Peptide - pharmacology | Swine | Tumor Necrosis Factor-alpha - immunology | Schistosoma mansoni - growth & development | Acute Disease | Vasodilator Agents - pharmacology | Schistosoma mansoni - immunology | gamma-Glutamyltransferase - metabolism | Aspartate Aminotransferases - metabolism | Schistosomiasis mansoni - metabolism | Animals | Interleukin-12 - immunology | Mice | Alanine Transaminase - metabolism | Liver - parasitology | Interleukin-10 - immunology | Tumor Necrosis Factor-alpha - biosynthesis
Journal Article
Infection and Immunity, ISSN 0019-9567, 02/2006, Volume 74, Issue 2, pp. 1215 - 1221
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 11/2004, Volume 173, Issue 10, pp. 6346 - 6356
of allergic responses in infected individuals. In this study we investigated whether experimental infection with Schistosoma mansoni could alter the... 
COLLAGEN-INDUCED ARTHRITIS | TH2 RESPONSES | ACTIVE FATAL ANAPHYLAXIS | CYTOKINE PRODUCTION | REGULATORY T-CELLS | GABONESE SCHOOLCHILDREN | ANTIGEN-PRESENTING CELLS | DEFICIENT MICE | IMMUNOLOGY | UP-REGULATION | MURINE SCHISTOSOMIASIS-MANSONI | Penicillin V - administration & dosage | Schistosomiasis mansoni - genetics | T-Lymphocyte Subsets - immunology | B-Lymphocyte Subsets - transplantation | Schistosomiasis mansoni - immunology | Anaphylaxis - prevention & control | Male | Th2 Cells - immunology | Adoptive Transfer | Interleukin-10 - physiology | Interleukin-4 - pharmacology | B-Lymphocyte Subsets - parasitology | Anaphylaxis - immunology | Mice, Inbred CBA | B-Lymphocyte Subsets - immunology | Female | Host-Parasite Interactions | Cytokines - genetics | Anaphylaxis - parasitology | Macrophages - immunology | Genetic Predisposition to Disease | Receptors, Interleukin-2 - biosynthesis | Mice, Inbred C57BL | Cells, Cultured | Penicillin V - immunology | Immunity, Innate | Th2 Cells - metabolism | Mice, Knockout | Anaphylaxis - genetics | Antigens, Differentiation - biosynthesis | Macrophages - metabolism | Animals | Schistosomiasis mansoni - parasitology | B-Lymphocyte Subsets - metabolism | Up-Regulation - immunology | T-Lymphocyte Subsets - metabolism | Immunization, Passive | Interleukin-10 - biosynthesis | Cytokines - deficiency | Mice | Mice, Inbred BALB C | Platelet Activating Factor - administration & dosage | Interleukin-10 - pharmacology | Macrophage-1 Antigen - biosynthesis
Journal Article
The Journal of Immunology, ISSN 0022-1767, 02/2008, Volume 180, Issue 4, pp. 2486 - 2495
Journal Article
The Journal of Immunology, ISSN 0022-1767, 12/2001, Volume 167, Issue 11, pp. 6533 - 6544
Type 2 cytokines regulate fibrotic liver pathology in mice infected with Schistosoma mansoni. Switching the immune response to a type 1-dominant reaction has... 
LIVER ARGINASE | TH2 CYTOKINES | HEALING WOUNDS | MYCOBACTERIUM-AVIUM INFECTION | IMMUNOLOGY | MURINE SCHISTOSOMIASIS | MARROW-DERIVED MACROPHAGES | HYDROXY-L-ARGININE | HEPATIC-FIBROSIS | T-CELLS | SCHISTOSOMA-MANSONI EGGS | Granuloma - prevention & control | Lung Diseases, Parasitic - immunology | Arginase - metabolism | Eflornithine - pharmacology | Th2 Cells - immunology | Nitric Oxide Synthase Type II | Schistosomiasis mansoni - enzymology | Disease Models, Animal | Tuberculosis - pathology | Proline - biosynthesis | Enzyme Inhibitors - pharmacology | Macrophage Activation | Mice, Knockout | Granuloma - pathology | Enzyme Induction - genetics | Macrophages - metabolism | Up-Regulation - immunology | Lung Diseases, Parasitic - enzymology | Liver Cirrhosis - pathology | Granuloma - immunology | Mice | Nitric Oxide Synthase - metabolism | Enzyme Activation - genetics | Arginine - metabolism | Schistosomiasis mansoni - genetics | Liver - enzymology | Schistosomiasis mansoni - immunology | Tuberculosis - enzymology | Interleukin-12 - physiology | Lung Diseases, Parasitic - pathology | Arginase - biosynthesis | Enzyme Induction - immunology | Liver Cirrhosis - enzymology | Th1 Cells - immunology | Enzyme Activation - immunology | Granuloma - enzymology | Enzyme Induction - drug effects | Female | Nitric Oxide Synthase - biosynthesis | Ovum - immunology | Arginase - antagonists & inhibitors | Macrophages - immunology | Mice, Inbred C57BL | Cells, Cultured | Up-Regulation - genetics | Mycobacterium avium - immunology | Enzyme Activation - drug effects | Tuberculosis - immunology | Ornithine Decarboxylase Inhibitors | Animals | Tuberculosis - genetics | Th1 Cells - enzymology | Schistosomiasis mansoni - pathology | Lung Diseases, Parasitic - genetics | Th2 Cells - enzymology
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 1999, Volume 104, Issue 6, pp. 777 - 785
In schistosomiasis, chronic parasite egg-induced granuloma formation can lead to tissue destruction and fibrosis, which causes much of the morbidity and... 
MEDICINE, RESEARCH & EXPERIMENTAL | INFECTED MICE | GRANULOMA-FORMATION | TH2 CELLS | MESSENGER-RNA | CLONING | IFN-GAMMA | INTERLEUKIN-13 RECEPTOR | IL-4-DEFICIENT MICE | CYTOKINE | MURINE SCHISTOSOMIASIS-MANSONI
Journal Article