Muscle & Nerve, ISSN 0148-639X, 10/2005, Volume 32, Issue 4, pp. 431 - 442
Muscle cramps are a common problem characterized by a sudden, painful, involuntary contraction of muscle. These true cramps, which originate from peripheral...
cramp–fasciculation | muscle pain | myalgia | quinine | spasm | fasciculation | amyotrophic lateral sclerosis (ALS) | Cramp-fasciculation | Amyotrophic lateral sclerosis (ALS) | Fasciculation | Spasm | Muscle pain | Myalgia | Quinine | NOCTURNAL LEG CRAMPS | cramp-fasciculation | NEUROSCIENCES | CLINICAL NEUROLOGY | PERIPHERAL-NERVE FUNCTION | QUININE SULFATE | SKELETAL-MUSCLE | SATOYOSHI-SYNDROME | CLINICAL SYMPTOMS | DOUBLE-BLIND | PLACEBO-CONTROLLED TRIAL | FLUID BALANCE | CHRONIC-RENAL-FAILURE | Muscle Cramp - physiopathology | Diagnosis, Differential | Motor Neurons - physiology | Motor Neuron Disease - complications | Humans | Muscle, Skeletal - innervation | Action Potentials - physiology | Muscle Cramp - diagnosis | Animals | Muscle Contraction - physiology | Muscle Cramp - etiology | Muscle, Skeletal - physiopathology | Motor Neuron Disease - physiopathology | Pain Measurement
cramp–fasciculation | muscle pain | myalgia | quinine | spasm | fasciculation | amyotrophic lateral sclerosis (ALS) | Cramp-fasciculation | Amyotrophic lateral sclerosis (ALS) | Fasciculation | Spasm | Muscle pain | Myalgia | Quinine | NOCTURNAL LEG CRAMPS | cramp-fasciculation | NEUROSCIENCES | CLINICAL NEUROLOGY | PERIPHERAL-NERVE FUNCTION | QUININE SULFATE | SKELETAL-MUSCLE | SATOYOSHI-SYNDROME | CLINICAL SYMPTOMS | DOUBLE-BLIND | PLACEBO-CONTROLLED TRIAL | FLUID BALANCE | CHRONIC-RENAL-FAILURE | Muscle Cramp - physiopathology | Diagnosis, Differential | Motor Neurons - physiology | Motor Neuron Disease - complications | Humans | Muscle, Skeletal - innervation | Action Potentials - physiology | Muscle Cramp - diagnosis | Animals | Muscle Contraction - physiology | Muscle Cramp - etiology | Muscle, Skeletal - physiopathology | Motor Neuron Disease - physiopathology | Pain Measurement
Journal Article
The Cochrane database of systematic reviews, ISSN 1469-493X, 2015, Volume 4, Issue 4, p. CD005044
Background Muscle cramps can occur anywhere and for many reasons. Quinine has been used to treat cramps of all causes. However, controversy continues about its...
Vitamins [therapeutic use] | VITAMIN-E | METAANALYSIS | NOCTURNAL LEG CRAMPS | EFFICACY | Quinine [adverse effects; therapeutic use] | Humans | RANDOMIZED CONTROLLED-TRIAL | Randomized Controlled Trials as Topic | NIGHT CRAMPS | Muscle Cramp [drug therapy] | Muscle Relaxants, Central [adverse effects; therapeutic use] | MEDICINE, GENERAL & INTERNAL | ANTIMALARIAL-DRUGS | Theophylline [therapeutic use] | Lidocaine [therapeutic use] | DISSEMINATED INTRAVASCULAR COAGULATION | Vitamin E [therapeutic use] | DOUBLE-BLIND | PLACEBO-CONTROLLED TRIAL | Drug Therapy, Combination | Theophylline - therapeutic use | Quinine - therapeutic use | Quinine - adverse effects | Vitamin E - therapeutic use | Lidocaine - therapeutic use | Muscle Relaxants, Central - adverse effects | Muscle Cramp - drug therapy | Vitamins - therapeutic use | Muscle Relaxants, Central - therapeutic use
Vitamins [therapeutic use] | VITAMIN-E | METAANALYSIS | NOCTURNAL LEG CRAMPS | EFFICACY | Quinine [adverse effects; therapeutic use] | Humans | RANDOMIZED CONTROLLED-TRIAL | Randomized Controlled Trials as Topic | NIGHT CRAMPS | Muscle Cramp [drug therapy] | Muscle Relaxants, Central [adverse effects; therapeutic use] | MEDICINE, GENERAL & INTERNAL | ANTIMALARIAL-DRUGS | Theophylline [therapeutic use] | Lidocaine [therapeutic use] | DISSEMINATED INTRAVASCULAR COAGULATION | Vitamin E [therapeutic use] | DOUBLE-BLIND | PLACEBO-CONTROLLED TRIAL | Drug Therapy, Combination | Theophylline - therapeutic use | Quinine - therapeutic use | Quinine - adverse effects | Vitamin E - therapeutic use | Lidocaine - therapeutic use | Muscle Relaxants, Central - adverse effects | Muscle Cramp - drug therapy | Vitamins - therapeutic use | Muscle Relaxants, Central - therapeutic use
Journal Article
Journal of clinical neuromuscular disease, ISSN 1522-0443, 1999
Journal
Cochrane database of systematic reviews (Online), ISSN 1469-493X, 2010, Volume 12, Issue 12, p. CD005044
Background Muscle cramps can occur anywhere and for many reasons. Quinine has been used to treat cramps of all causes. However, controversy continues about its...
RELIEF | MEDICINE, GENERAL & INTERNAL | ANTIMALARIAL-DRUGS | Theophylline - therapeutic use | Quinine - therapeutic use | Quinine - adverse effects | Humans | Vitamin E - therapeutic use | Lidocaine - therapeutic use | Muscle Relaxants, Central - adverse effects | Drug Therapy, Combination | Muscle Cramp - drug therapy | Vitamins - therapeutic use | Muscle Relaxants, Central - therapeutic use | Randomized Controlled Trials as Topic
RELIEF | MEDICINE, GENERAL & INTERNAL | ANTIMALARIAL-DRUGS | Theophylline - therapeutic use | Quinine - therapeutic use | Quinine - adverse effects | Humans | Vitamin E - therapeutic use | Lidocaine - therapeutic use | Muscle Relaxants, Central - adverse effects | Drug Therapy, Combination | Muscle Cramp - drug therapy | Vitamins - therapeutic use | Muscle Relaxants, Central - therapeutic use | Randomized Controlled Trials as Topic
Journal Article
1997, ISBN 9783211827925, x, 144
Book
British Journal of Sports Medicine, ISSN 0306-3674, 06/2009, Volume 43, Issue 6, pp. 401 - 408
Exercise Associated Muscle Cramps (EAMC) is one of the most common conditions that require medical attention during or immediately after sports events. Despite...
SODIUM LOSSES | RESPONSES | SPORT SCIENCES | TRIATHLONS | MANAGEMENT | MEDICAL PROBLEMS | HYPOTHESIS | EXERTIONAL HEAT ILLNESS | HUMANS | RELIABILITY | HYDRATION | Muscle Cramp - physiopathology | Epidemiologic Methods | Dehydration - complications | Humans | Muscle Cramp - etiology | Exercise - physiology | Water-Electrolyte Imbalance - complications | Muscle Fatigue - physiology | Muscle cramps | Complications and side effects | Exercise | Physiological aspects | Electrolytes | Research | Dehydration (Physiology) | Athletes | Triathlon | Laboratories | Funding | Multivariate analysis | Evidence-based medicine | Sports medicine | Medicine | Studies | Physical fitness | Hypotheses | Sodium | Marathons | Muscle pain | Health risk assessment
SODIUM LOSSES | RESPONSES | SPORT SCIENCES | TRIATHLONS | MANAGEMENT | MEDICAL PROBLEMS | HYPOTHESIS | EXERTIONAL HEAT ILLNESS | HUMANS | RELIABILITY | HYDRATION | Muscle Cramp - physiopathology | Epidemiologic Methods | Dehydration - complications | Humans | Muscle Cramp - etiology | Exercise - physiology | Water-Electrolyte Imbalance - complications | Muscle Fatigue - physiology | Muscle cramps | Complications and side effects | Exercise | Physiological aspects | Electrolytes | Research | Dehydration (Physiology) | Athletes | Triathlon | Laboratories | Funding | Multivariate analysis | Evidence-based medicine | Sports medicine | Medicine | Studies | Physical fitness | Hypotheses | Sodium | Marathons | Muscle pain | Health risk assessment
Journal Article
Cochrane database of systematic reviews (Online), ISSN 1469-493X, 2012, Volume 9, Issue 9, p. CD009402
Background Skeletal muscle cramps are common and often presented to physicians in association with pregnancy, advanced age, exercise or disorders of the motor...
SUPPLEMENTATION | SUBSTITUTION | MEDICINE, GENERAL & INTERNAL | SERUM | NOCTURNAL LEG CRAMPS | DEFICIENCY | Cross-Over Studies | Pregnancy | Age Factors | Humans | Muscle Cramp - etiology | Female | Male | Muscle, Skeletal | Muscle Cramp - drug therapy | Magnesium - therapeutic use | Pregnancy Complications - drug therapy | Randomized Controlled Trials as Topic
SUPPLEMENTATION | SUBSTITUTION | MEDICINE, GENERAL & INTERNAL | SERUM | NOCTURNAL LEG CRAMPS | DEFICIENCY | Cross-Over Studies | Pregnancy | Age Factors | Humans | Muscle Cramp - etiology | Female | Male | Muscle, Skeletal | Muscle Cramp - drug therapy | Magnesium - therapeutic use | Pregnancy Complications - drug therapy | Randomized Controlled Trials as Topic
Journal Article
European Journal of Gastroenterology & Hepatology, ISSN 0954-691X, 03/2019, Volume 31, Issue 3, pp. 375 - 381
INTRODUCTIONMuscle cramps are common comorbidities in chronic liver disease (CLD). Although the prevalence of these has been reported in patients with liver...
prevalence | nonalcoholic fatty liver disease | muscle cramps | SIMPLE NONINVASIVE INDEX | PREDICT | SIGNIFICANT FIBROSIS | CIRRHOSIS | chronic liver disease | quality of life | GASTROENTEROLOGY & HEPATOLOGY | Muscle cramps | Complications and side effects | Development and progression | Care and treatment | Liver diseases
prevalence | nonalcoholic fatty liver disease | muscle cramps | SIMPLE NONINVASIVE INDEX | PREDICT | SIGNIFICANT FIBROSIS | CIRRHOSIS | chronic liver disease | quality of life | GASTROENTEROLOGY & HEPATOLOGY | Muscle cramps | Complications and side effects | Development and progression | Care and treatment | Liver diseases
Journal Article
American Family Physician, ISSN 0002-838X, 2012, Volume 86, Issue 4, pp. 350 - 355
Up to 60 percent of adults report that they have had nocturnal leg cramps. The recurrent, painful tightening usually occurs in the calf muscles and can cause...
Internal Medicine | MEDICINE, GENERAL & INTERNAL | QUININE | PRIMARY HEALTH CARE | RANDOMIZED CONTROLLED-TRIAL | PREVALENCE | MUSCLE CRAMPS | Restless Legs Syndrome - diagnosis | Diagnosis, Differential | Sleep-Wake Transition Disorders - therapy | Sleep-Wake Transition Disorders - etiology | Sleep-Wake Transition Disorders - chemically induced | Humans | Adult | Sleep-Wake Transition Disorders - diagnosis | Muscle cramps | Extremities, Lower | Leg
Internal Medicine | MEDICINE, GENERAL & INTERNAL | QUININE | PRIMARY HEALTH CARE | RANDOMIZED CONTROLLED-TRIAL | PREVALENCE | MUSCLE CRAMPS | Restless Legs Syndrome - diagnosis | Diagnosis, Differential | Sleep-Wake Transition Disorders - therapy | Sleep-Wake Transition Disorders - etiology | Sleep-Wake Transition Disorders - chemically induced | Humans | Adult | Sleep-Wake Transition Disorders - diagnosis | Muscle cramps | Extremities, Lower | Leg
Journal Article
Muscle & Nerve, ISSN 0148-639X, 08/2013, Volume 48, Issue 2, pp. 252 - 255
ABSTRACT Introduction: Muscle cramps are a common complaint and are thought to arise from spontaneous discharges of the motor nerve terminal. Polyneuropathy is...
muscle cramps | unmyelinated nerve fibers | skin biopsy | small‐fiber neuropathy | peripheral nervous system disease | Muscle cramps | Skin biopsy | Small-fiber neuropathy | Peripheral nervous system disease | Unmyelinated nerve fibers | POPULATION | PAIN | small-fiber neuropathy | NEUROSCIENCES | CLINICAL NEUROLOGY | LEG | Peripheral Nervous System Diseases - diagnosis | Humans | Middle Aged | Male | Neural Conduction - physiology | Action Potentials - physiology | Muscle Cramp - complications | Muscle Cramp - diagnosis | Nerve Fibers - physiology | Biopsy | Creatine Kinase - metabolism | Adult | Female | Electromyography | Peripheral Nervous System Diseases - complications | Skin - pathology | Muscular system | Muscle pain
muscle cramps | unmyelinated nerve fibers | skin biopsy | small‐fiber neuropathy | peripheral nervous system disease | Muscle cramps | Skin biopsy | Small-fiber neuropathy | Peripheral nervous system disease | Unmyelinated nerve fibers | POPULATION | PAIN | small-fiber neuropathy | NEUROSCIENCES | CLINICAL NEUROLOGY | LEG | Peripheral Nervous System Diseases - diagnosis | Humans | Middle Aged | Male | Neural Conduction - physiology | Action Potentials - physiology | Muscle Cramp - complications | Muscle Cramp - diagnosis | Nerve Fibers - physiology | Biopsy | Creatine Kinase - metabolism | Adult | Female | Electromyography | Peripheral Nervous System Diseases - complications | Skin - pathology | Muscular system | Muscle pain
Journal Article
Circulation, ISSN 0009-7322, 10/2011, Volume 124, Issue 16, pp. 1774 - 1782
LONG-TERM PROGNOSIS | OXIDE SYNTHASE GENE | OXIDATIVE STRESS | CARDIAC & CARDIOVASCULAR SYSTEMS | VASOSPASTIC ANGINA | MYOCARDIAL-INFARCTION | angina | PIGS IN-VIVO | coronary spastic angina | CALCIUM-CHANNEL BLOCKERS | VASCULAR SMOOTH-MUSCLE | ENDOTHELIUM-DEPENDENT VASODILATION | coronary spasm | pathophysiology | VARIANT ANGINA-PECTORIS | PERIPHERAL VASCULAR DISEASE | Inflammation - pathology | Muscle, Smooth, Vascular - pathology | Coronary Vasospasm - etiology | Endothelial Cells - pathology | Humans | Risk Factors | Coronary vasospasm | Angina pectoris | Development and progression
Journal Article
American Family Physician, ISSN 0002-838X, 2016, Volume 93, Issue 3, pp. 177 - 178
Aaron Saguil ; Rebecca Lauters
Internal Medicine | Quinine - therapeutic use | Muscle Cramp - drug therapy | Humans | Muscle Relaxants, Central - therapeutic use | Leg | Muscle cramps | Treatment outcome | Care and treatment | Dosage and administration | Quinine | Analysis
Internal Medicine | Quinine - therapeutic use | Muscle Cramp - drug therapy | Humans | Muscle Relaxants, Central - therapeutic use | Leg | Muscle cramps | Treatment outcome | Care and treatment | Dosage and administration | Quinine | Analysis
Journal Article
CMAJ, ISSN 0820-3946, 07/2015, Volume 187, Issue 10, pp. 757 - 757
Journal Article
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, ISSN 0820-3946, 07/2015, Volume 187, Issue 10, pp. 757 - 757
Journal Article
Neurology, ISSN 0028-3878, 04/2016, Volume 86, Issue 16, pp. 1474 - 1481
OBJECTIVE:To determine the safety and tolerability of mexiletine in a phase II double-blind randomized controlled trial of sporadic amyotrophic lateral...
AMERICAN ACADEMY | RILUZOLE | CORTICAL HYPEREXCITABILITY | CORTICOMOTOR THRESHOLD | DOUBLE-BLIND | PRACTICE PARAMETER UPDATE | PATIENT | AMYOTROPHIC-LATERAL-SCLEROSIS | PLACEBO-CONTROLLED TRIAL | QUALITY STANDARDS SUBCOMMITTEE | CLINICAL NEUROLOGY | Muscle Cramp - physiopathology | Voltage-Gated Sodium Channel Blockers - pharmacokinetics | Amyotrophic Lateral Sclerosis - physiopathology | Follow-Up Studies | Humans | Mexiletine - pharmacokinetics | Middle Aged | Mexiletine - therapeutic use | Male | Treatment Outcome | Postural Balance - drug effects | Amyotrophic Lateral Sclerosis - drug therapy | Disease Progression | Dose-Response Relationship, Drug | Mexiletine - adverse effects | Voltage-Gated Sodium Channel Blockers - therapeutic use | Female | Muscle Cramp - drug therapy | Voltage-Gated Sodium Channel Blockers - adverse effects | 177 | 112 | 321 | 178
AMERICAN ACADEMY | RILUZOLE | CORTICAL HYPEREXCITABILITY | CORTICOMOTOR THRESHOLD | DOUBLE-BLIND | PRACTICE PARAMETER UPDATE | PATIENT | AMYOTROPHIC-LATERAL-SCLEROSIS | PLACEBO-CONTROLLED TRIAL | QUALITY STANDARDS SUBCOMMITTEE | CLINICAL NEUROLOGY | Muscle Cramp - physiopathology | Voltage-Gated Sodium Channel Blockers - pharmacokinetics | Amyotrophic Lateral Sclerosis - physiopathology | Follow-Up Studies | Humans | Mexiletine - pharmacokinetics | Middle Aged | Mexiletine - therapeutic use | Male | Treatment Outcome | Postural Balance - drug effects | Amyotrophic Lateral Sclerosis - drug therapy | Disease Progression | Dose-Response Relationship, Drug | Mexiletine - adverse effects | Voltage-Gated Sodium Channel Blockers - therapeutic use | Female | Muscle Cramp - drug therapy | Voltage-Gated Sodium Channel Blockers - adverse effects | 177 | 112 | 321 | 178
Journal Article
Clinical Gastroenterology and Hepatology, ISSN 1542-3565, 2013, Volume 11, Issue 11, pp. 1385 - 1391
Muscle cramps are common in patients with liver disease and adversely influence quality of life. The exact mechanisms by which they occur remain unclear,...
Gastroenterology and Hepatology | Chronic Liver Disease | VITAMIN-E-DEFICIENCY | EPERISONE HYDROCHLORIDE | SKELETAL-MUSCLE | CHLORIDE CHANNELS | HEPATIC NEUROPATHY | CHAIN AMINO-ACIDS | CIRRHOTIC-PATIENTS | QUININE | QUALITY-OF-LIFE | TAURINE | GASTROENTEROLOGY & HEPATOLOGY | Liver Diseases - complications | Muscle Cramp - therapy | Muscle Cramp - pathology | Humans | Muscle Cramp - etiology | Muscle cramps | Continuing medical education | Liver diseases | Muscle proteins | Adenosine triphosphate
Gastroenterology and Hepatology | Chronic Liver Disease | VITAMIN-E-DEFICIENCY | EPERISONE HYDROCHLORIDE | SKELETAL-MUSCLE | CHLORIDE CHANNELS | HEPATIC NEUROPATHY | CHAIN AMINO-ACIDS | CIRRHOTIC-PATIENTS | QUININE | QUALITY-OF-LIFE | TAURINE | GASTROENTEROLOGY & HEPATOLOGY | Liver Diseases - complications | Muscle Cramp - therapy | Muscle Cramp - pathology | Humans | Muscle Cramp - etiology | Muscle cramps | Continuing medical education | Liver diseases | Muscle proteins | Adenosine triphosphate
Journal Article