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1. Full Text Alternatively spliced androgen receptor variants
by Scott M Dehm and Donald J Tindall
Endocrine-Related Cancer, ISSN 1351-0088, 10/2011, Volume 18, Issue 5, pp. R183 - R196
Alternative splicing is an important mechanism for increasing functional diversity from a limited set of genes. Deregulation of this process is common in... 
Prostatic Neoplasms - metabolism | Alternative Splicing | Exons | Humans | Receptors, Androgen - metabolism | Gene Expression Regulation, Neoplastic | Male | Androgen-Insensitivity Syndrome - genetics | Animals | Prostatic Neoplasms - genetics | Receptors, Androgen - genetics | Androgen-Insensitivity Syndrome - metabolism | Protein Isoforms | GENE-MUTATIONS | AMINO-TERMINAL DOMAIN | POINT MUTATION | MESSENGER-RNA | ONCOLOGY | STRUCTURAL BASIS | SITE MUTATION | ENDOCRINOLOGY & METABOLISM | BINDING DOMAIN | RESISTANT PROSTATE-CANCER | ANTITUMOR-ACTIVITY | DONOR SITE
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2. Full Text Androgen Receptor in Prostate Cancer
by Heinlein, Cynthia A and Chang, Chawnshang
Endocrine Reviews, ISSN 0163-769X, 04/2004, Volume 25, Issue 2, pp. 276 - 308
The normal development and maintenance of the prostate is dependent on androgen acting through the androgen receptor (AR). AR remains important in the... 
LIGAND-INDEPENDENT ACTIVATION | ACTIVATED PROTEIN-KINASE | ETS TRANSCRIPTION FACTOR | RAT VENTRAL PROSTATE | PHOSPHATIDYLINOSITOL 3-KINASE/AKT PATHWAY | EPIDERMAL-GROWTH-FACTOR | ENDOCRINOLOGY & METABOLISM | ANTIGEN GENE-EXPRESSION | CELL-LINE LNCAP | HORMONE-BINDING GLOBULIN | CAG REPEAT POLYMORPHISM | Prostate-Specific Antigen | Prostatic Neoplasms - pathology | Gene Expression | Androgens - physiology | Androgen Antagonists | Humans | Androgens - deficiency | Prostate - growth & development | Male | Prostatic Neoplasms - physiopathology | Prostate - embryology | Prostate - pathology | Animals | Receptors, Androgen - genetics | Cell Division | Growth Substances - pharmacology | Repetitive Sequences, Nucleic Acid | Transcription, Genetic | Mutation | Genes, Tumor Suppressor | Receptors, Androgen - physiology | Apoptosis
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3. Full Text Glucocorticoid Receptor Confers Resistance to Antiandrogens by Bypassing Androgen Receptor Blockade
by Arora, Vivek K and Schenkein, Emily and Murali, Rajmohan and Subudhi, Sumit K and Wongvipat, John and Balbas, Minna D and Shah, Neel and Cai, Ling and Efstathiou, Eleni and Logothetis, Chris and Zheng, Deyou and Sawyers, Charles L
Cell, ISSN 0092-8674, 12/2013, Volume 155, Issue 6, pp. 1309 - 1322
The treatment of advanced prostate cancer has been transformed by novel antiandrogen therapies such as enzalutamide. Here, we identify induction of... 
LUNG-CANCER | GEFITINIB | INHIBITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROSTATE-CANCER | MUTATION | GROWTH | INCREASED SURVIVAL | ABIRATERONE | ENZALUTAMIDE | CELL BIOLOGY | Neoplasm Transplantation | Androgen Receptor Antagonists - therapeutic use | Phenylthiohydantoin - therapeutic use | Humans | Receptors, Androgen - metabolism | Gene Expression Regulation | Transcriptome | Drug Resistance, Neoplasm | Male | Receptors, Glucocorticoid - metabolism | Phenylthiohydantoin - analogs & derivatives | Animals | Heterografts | Androgen Antagonists - therapeutic use | Mice | Prostatic Neoplasms - drug therapy | Disease Models, Animal
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4. Full Text Androgen receptor roles in spermatogenesis and infertility
by O'Hara, Laura, Ph.D and Smith, Lee B., Ph.D
Best Practice & Research: Clinical Endocrinology & Metabolism, ISSN 1521-690X, 2015, Volume 29, Issue 4, pp. 595 - 605
Androgens such as testosterone are steroid hormones essential for normal male reproductive development and function. Mutations of androgen receptors (AR) are... 
Endocrinology & Metabolism | spermatogenesis | androgen receptor | testosterone | transgenic mice | male infertility | testes | LEYDIG-CELLS | TESTICULAR PERITUBULAR CELLS | SERTOLI-CELL | MICE LACKING | SEMINIFEROUS EPITHELIUM | SMOOTH-MUSCLE | SPERMIATION FAILURE | GERM-CELLS | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | SELECTIVE KNOCKOUT | Animals | Infertility, Male - genetics | Receptors, Androgen - genetics | Spermatogenesis | Humans | Receptors, Androgen - metabolism | Infertility, Male - metabolism | Male | Mutation | Infertility, Male - pathology | Testosterone | Genetic engineering | Analysis | Infertility
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5. Full Text Emerging mechanisms of resistance to androgen receptor inhibitors in prostate cancer
by Watson, Philip A and Arora, Vivek K and Sawyers, Charles L
Nature Reviews Cancer, ISSN 1474-175X, 11/2015, Volume 15, Issue 12, pp. 701 - 711
During the past 10 years, preclinical studies implicating sustained androgen receptor (AR) signalling as the primary driver of castration-resistant prostate... 
MOLECULAR CHARACTERIZATION | SELECTIVE-INHIBITION | POLY(ADP-RIBOSE) POLYMERASE | ONCOLOGY | BRCA MUTATION CARRIERS | SMALL-CELL CARCINOMA | ABIRATERONE ACETATE | PROGESTERONE-RECEPTOR | ANTITUMOR-ACTIVITY | SPLICE VARIANTS | WITHDRAWAL SYNDROME | Androgen Receptor Antagonists - therapeutic use | Animals | Prostatic Neoplasms - genetics | Humans | Drug Resistance, Neoplasm | Male | Gene Expression Regulation, Neoplastic - genetics | Prostatic Neoplasms - drug therapy | Gene mutations | Development and progression | Genetic aspects | Cellular signal transduction | Drug resistance | Prostate cancer | Health aspects | Identification and classification
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6. Full Text The androgen receptor gene mutations database: 2012 update
by Gottlieb, Bruce and Beitel, Lenore K and Nadarajah, Abbesha and Paliouras, Miltiadis and Trifiro, Mark
Human Mutation, ISSN 1059-7794, 05/2012, Volume 33, Issue 5, pp. 887 - 894
The current version of the androgen receptor gene (AR) mutations database is described. A major change to the database is that the nomenclature and numbering... 
genotype–phenotype | prostate cancer | androgen receptor | AIS | Prostate cancer | Androgen receptor | Genotype-phenotype | INSENSITIVITY SYNDROME | genotype-phenotype | SOMATIC MOSAICISM | MUTANTS | REFRACTORY PROSTATE-CANCER | MOUSE MODEL | MEN | GENETICS & HEREDITY | ASSOCIATION | EXPRESSION | CAG REPEAT POLYMORPHISM | BULBAR MUSCULAR-ATROPHY | Genetic Predisposition to Disease | Bulbo-Spinal Atrophy, X-Linked - genetics | Humans | Receptors, Androgen - metabolism | Risk Factors | Databases, Genetic | Terminology as Topic | Male | Protein Structure, Tertiary - genetics | Mutation, Missense | Androgen-Insensitivity Syndrome - genetics | Animals | Prostatic Neoplasms - genetics | Receptors, Androgen - genetics | Protein Isoforms - chemistry | Primary Ovarian Insufficiency - genetics | Protein Binding | Female | Receptors, Androgen - chemistry | Adaptor Proteins, Signal Transducing - metabolism | Protein Isoforms - genetics
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7. Full Text Androgen receptor signaling in prostate cancer
by Culig, Zoran and Santer, Frédéric R
Cancer and Metastasis Reviews, ISSN 0167-7659, 9/2014, Volume 33, Issue 2, pp. 413 - 427
The androgen receptor (AR), ligand-induced transcription factor, is expressed in primary prostate cancer and in metastases. AR regulates multiple cellular... 
Biomedicine | Migration | Androgen receptor | Coactivator | Truncated receptor | Cancer Research | Oncology | miRNA | Mutation | Biomedicine general | LIGAND-INDEPENDENT ACTIVATION | CELL-CYCLE ARREST | SPLICE VARIANTS | EPITHELIAL-MESENCHYMAL TRANSITION | PHASE-II TRIAL | 17,20-LYASE INHIBITOR | ONCOLOGY | RAT VENTRAL PROSTATE | EPIDERMAL-GROWTH-FACTOR | ANTI-INTERLEUKIN-6 MONOCLONAL-ANTIBODY | LNCAP CELLS | Prostatic Neoplasms - metabolism | Prostatic Neoplasms - pathology | Signal Transduction | Humans | Receptors, Androgen - metabolism | Gene Expression Regulation, Neoplastic | Male | Molecular Targeted Therapy | Transcription Factors - metabolism | Animals | Prostatic Neoplasms - genetics | Receptors, Androgen - genetics | Ligands | Transcription, Genetic | Prostatic Neoplasms - drug therapy | Development and progression | Androgens | MicroRNA | Hormones | Peptides | Prostate cancer
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