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Journal of Clinical Investigation, ISSN 0021-9738, 05/2009, Volume 119, Issue 5, pp. 1109 - 1123
Imatinib mesylate (IM), a potent inhibitor of the BCR/ABL tyrosine kinase, has become standard first-line therapy for patients with chronic myeloid leukemia... 
CHRONIC MYELOGENOUS LEUKEMIA | MEDICINE, RESEARCH & EXPERIMENTAL | MALIGNANT GLIOMA-CELLS | BLAST CRISIS | CLINICAL RESISTANCE | BCR-ABL MUTATIONS | ENDOPLASMIC-RETICULUM | CYTOCHROME-C RELEASE | CASPASE ACTIVATION | IMATINIB RESISTANCE | CHRONIC MYELOID-LEUKEMIA | Transcription Factor CHOP - genetics | Neoplastic Stem Cells - cytology | Gene Expression - drug effects | Calcium - metabolism | Gene Expression - genetics | Microtubule-Associated Proteins - metabolism | Neoplastic Stem Cells - drug effects | Humans | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Endoplasmic Reticulum - metabolism | Antineoplastic Agents - therapeutic use | Autophagy - physiology | Thiazoles - therapeutic use | Autophagy - drug effects | Chloroquine - pharmacology | Neoplastic Stem Cells - metabolism | RNA Interference | Endoplasmic Reticulum - drug effects | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology | Macrolides - pharmacology | Antineoplastic Agents - pharmacology | Cell Death - drug effects | Dasatinib | Chloroquine - therapeutic use | Piperazines - therapeutic use | Pyrimidines - pharmacology | Imatinib Mesylate | Piperazines - pharmacology | Mice, Inbred C3H | Xenograft Model Antitumor Assays | Fusion Proteins, bcr-abl - genetics | Animals | Cell Death - physiology | Protein Kinase Inhibitors - therapeutic use | Pyrimidines - therapeutic use | Fusion Proteins, bcr-abl - antagonists & inhibitors | Cell Line, Tumor | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - metabolism | Mice | Protein Kinase Inhibitors - pharmacology | Thiazoles - pharmacology | Benzamides | Macrolides - therapeutic use | Protein-Tyrosine Kinases - antagonists & inhibitors | Causes of | Physiological aspects | Genetic aspects | Chronic myeloid leukemia | Research | Drug therapy | Phagocytosis | Index Medicus | Abridged Index Medicus
Journal Article
Biology of Blood and Marrow Transplantation, ISSN 1083-8791, 2017, Volume 23, Issue 3, pp. 452 - 458
Journal Article
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 04/2013, Volume 73, Issue 8, pp. 2435 - 2444
Journal Article
International Journal of Cancer, ISSN 0020-7136, 05/2013, Volume 132, Issue 9, pp. 2006 - 2019
To identify molecular targets in leukemia stem cells (LSCs), this study compared the protein expression profile of freshly isolated CD34 + /CD38 − cells with... 
AML | leukemia stem cells | CD82 | MMP9 | bone marrow microenvironment | ABILITY IN-VITRO | PROGENITOR CELLS | REPOPULATING CELLS | SCID MICE | BONE-MARROW | KINASE | ACUTE MYELOID-LEUKEMIA | ONCOLOGY | MOUSE MODEL | C-MET | STEM/PROGENITOR CELLS | RNA, Small Interfering - genetics | Antigens, CD34 - metabolism | Cell Proliferation | Humans | Leukemia, Myeloid, Acute - metabolism | Gene Expression Regulation, Neoplastic | Immunoenzyme Techniques | Matrix Metalloproteinase 9 - metabolism | Flow Cytometry | Kangai-1 Protein - metabolism | Neoplastic Stem Cells - metabolism | Matrix Metalloproteinase 9 - genetics | Bone Marrow Transplantation | Kangai-1 Protein - genetics | Neoplastic Stem Cells - pathology | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Tumor Cells, Cultured | Real-Time Polymerase Chain Reaction | ADP-ribosyl Cyclase 1 - genetics | Leukemia, Myeloid, Acute - pathology | Matrix Metalloproteinase 2 - metabolism | RNA, Messenger - genetics | Mesenchymal Stromal Cells - metabolism | Kangai-1 Protein - antagonists & inhibitors | Reverse Transcriptase Polymerase Chain Reaction | Cell Adhesion | Blotting, Western | Peptide Fragments - analysis | Matrix Metalloproteinase 2 - genetics | Animals | ADP-ribosyl Cyclase 1 - metabolism | Mice, Inbred NOD | Mice | Mesenchymal Stromal Cells - pathology | Homeodomain Proteins - physiology | Antigens, CD34 - genetics | Cell Movement | Leukemia, Myeloid, Acute - genetics | Fibronectins | Medical colleges | RNA | Drug resistance | Analysis | Stem cells | Bone marrow | Glycoproteins | Leukemia | Cell adhesion & migration | Index Medicus
Journal Article
Science, ISSN 0036-8075, 4/2012, Volume 336, Issue 6077, pp. 86 - 90
Macrophages and dendritic cells (DCs) are key components of cellular immunity and are thought to originate and renew from hematopoietic stem cells (HSCs).... 
Bacteriophages | Kidneys | Lungs | Blood cells | Liver | REPORTS | Islets of Langerhans | Macrophages | Embryos | Blood | Hematopoietic stem cells | MICROGLIA DERIVE | IMMUNOHISTOCHEMICAL LOCALIZATION | YOLK-SAC | MULTIDISCIPLINARY SCIENCES | FLT3 EXPRESSION | SELF-RENEWAL | C-MYB | MONONUCLEAR PHAGOCYTE SYSTEM | TRANSCRIPTION FACTOR | AORTIC ENDOTHELIUM | LANGERHANS CELLS | Myeloid Cells - cytology | Cell Proliferation | Myeloid Cells - physiology | Dendritic Cells - physiology | Genes, myb | Liver - embryology | Yolk Sac - cytology | Microglia - physiology | Gene Expression Regulation, Developmental | Gene Deletion | Trans-Activators - genetics | Hematopoietic Stem Cells - physiology | Myelopoiesis | Macrophages - physiology | Microglia - cytology | Proto-Oncogene Proteins - metabolism | Kupffer Cells - cytology | Kupffer Cells - physiology | Proto-Oncogene Proteins - genetics | Macrophages - cytology | Chick Embryo | Proto-Oncogene Proteins c-myb - metabolism | Cell Lineage | Animals | Embryo, Mammalian - cytology | Hematopoietic Stem Cells - cytology | Langerhans Cells - physiology | Trans-Activators - metabolism | Dendritic Cells - cytology | Mice | Langerhans Cells - cytology | Physiological aspects | Transcription factors | Dendritic cells | Health aspects | Infections | Rodents | Inflammatory diseases | Stem cells | Index Medicus
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 2015, Volume 212, Issue 3, pp. 351 - 367
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 511, Issue 7509, pp. 312 - 318
Journal Article