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1975, ISBN 088416022X, 126
Book
Journal of Clinical Investigation, ISSN 0021-9738, 08/2016, Volume 126, Issue 8, pp. 2867 - 2880
Journal Article
PLoS Medicine, ISSN 1549-1277, 2006, Volume 3, Issue 7, pp. 1140 - 1151
The JAK2V617F allele has recently been identified in patients with polycythemia vera (PV), essential thrombocytosis (ET), and myelofibrosis with myeloid... 
Recombinant Fusion Proteins - adverse effects | Humans | Myeloproliferative Disorders - pathology | Mutation, Missense | Primary Myelofibrosis - pathology | Receptors, Cytokine - physiology | Janus Kinases - physiology | Bone Marrow Transplantation | Hematopoiesis - physiology | Myeloid Cells - drug effects | Transcription, Genetic | Colony-Forming Units Assay | Phosphorylation - drug effects | mRNA Cleavage and Polyadenylation Factors - genetics | Hematologic Neoplasms - physiopathology | Disease Models, Animal | Cells, Cultured - drug effects | Bone Marrow Cells - pathology | Hematopoiesis - genetics | Signal Transduction - genetics | Thrombocytosis - etiology | Sequence Analysis, DNA | Cell Division - drug effects | mRNA Cleavage and Polyadenylation Factors - physiology | Receptor, Platelet-Derived Growth Factor alpha - physiology | Hematologic Neoplasms - drug therapy | Mice | Mice, Inbred BALB C | Myeloid Cells - pathology | Protein Processing, Post-Translational - genetics | Myeloproliferative Disorders - genetics | Oncogene Proteins, Fusion - physiology | STAT Transcription Factors - physiology | Protein Processing, Post-Translational - drug effects | Cells, Cultured - pathology | Bone Marrow Cells - drug effects | Spleen - pathology | Thrombocytosis - pathology | Gene Expression Regulation | Janus Kinases - antagonists & inhibitors | Point Mutation | Megakaryocytes - pathology | Primary Myelofibrosis - genetics | Animals | Oncogene Proteins, Fusion - genetics | Protein Kinase Inhibitors - therapeutic use | Receptor, Platelet-Derived Growth Factor alpha - genetics | Myeloproliferative Disorders - etiology | Signal Transduction - physiology | Protein Kinase Inhibitors - pharmacology | Genetic Vectors | Megakaryocytes - drug effects | Cytokines - pharmacology | Amino Acid Substitution | Thrombocytosis - genetics | Genetic aspects | Myelofibrosis | Research | Hematology | Gene Therapy | Genomics | Genetics | Oncology | Cancer Biology | Hematology (including Blood Transfusion)
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2012, Volume 109, Issue 41, pp. 16630 - 16635
Airway mucus plays a critical role in clearing inhaled toxins, particles, and pathogens. Diverse toxic, inflammatory, and infectious insults induce airway... 
Metaplasia | Intestines | Lungs | Epithelial cells | Lung diseases | Cell lines | Goblets | Infections | Mucus | Inflammation | Innate immunity | Airway epithelium | PULMONARY | innate immunity | RECOGNITION | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | airway epithelium | HOST-DEFENSE | EXPRESSION | Epithelial Cells - metabolism | Lung Diseases - metabolism | Respiratory Mucosa - drug effects | Gene Expression - drug effects | Proto-Oncogene Proteins c-ets - genetics | Epithelial Cells - drug effects | Humans | Adaptor Proteins, Vesicular Transport - genetics | Rhinovirus - physiology | Lung Diseases - drug therapy | Adaptor Proteins, Vesicular Transport - metabolism | Respiratory Mucosa - pathology | HEK293 Cells | Proto-Oncogene Proteins c-ets - metabolism | Toll-Like Receptors - metabolism | Signal Transduction | Myeloid Differentiation Factor 88 - genetics | Immunity, Innate | Interleukin-13 - pharmacology | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Host-Pathogen Interactions | Microscopy, Confocal | Animals | Epithelial Cells - virology | Toll-Like Receptors - genetics | Lipopolysaccharides - pharmacology | Protein Binding | Doxycycline - pharmacology | Anti-Bacterial Agents - pharmacology | Mice | Lung Diseases - pathology | Respiratory Mucosa - metabolism | Myeloid Differentiation Factor 88 - metabolism | Physiological aspects | Development and progression | Health aspects | Airway (Medicine) | Cytoplasm | Biological Sciences
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, p. e58935
Chronic inflammation in the stomach induces metaplasia, the pre-cancerous lesion that precedes inflammation-driven neoplastic transformation. While Hedgehog... 
ACTIVATION | SONIC HEDGEHOG | SIGNALING PATHWAY | INTERLEUKIN-1-BETA | MULTIDISCIPLINARY SCIENCES | ATROPHIC GASTRITIS | IL-6 PRODUCTION | KAPPA-B | SUPPRESSOR-CELLS | CANCER | TUMOR MICROENVIRONMENT | Gastritis - metabolism | Oligonucleotide Array Sequence Analysis | Gastritis - genetics | Helicobacter Infections - prevention & control | Ki-67 Antigen - metabolism | Gene Expression Profiling | Antigens, CD - genetics | Helicobacter Infections - pathology | Antigens, CD - metabolism | Gastritis - pathology | Kruppel-Like Transcription Factors - metabolism | Gene Deletion | Gastritis - microbiology | Helicobacter Infections - metabolism | Cytokines - genetics | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | Gene Expression Regulation - genetics | Mice, Transgenic | Helicobacter Infections - genetics | Carrier Proteins - genetics | Metaplasia | Animals | Carrier Proteins - metabolism | Ki-67 Antigen - genetics | Myeloid Cells - metabolism | Helicobacter felis | Mice | Zinc Finger Protein GLI1 | Myeloid Cells - pathology | Chronic Disease | Kruppel-Like Transcription Factors - genetics | Cytokines - biosynthesis | Infection | DNA microarrays | Analysis | Genes | Helicobacter infections | Inflammation | Cell differentiation | Health aspects | Transformation | Infections | Kinases | Stomach cancer | CD45 antigen | Interleukin 6 | Immunology | Clonal deletion | Rodents | Gastroenterology | Deletion | Neck | Gastric cancer | CD11c antigen | Stomach | Dysplasia | Myeloid cells | CD11b antigen | Cytokines | Internal medicine | Stat3 protein | Tumor necrosis factor-α | Gene expression | Gastritis | Medicine | Signaling | Hedgehog protein | Transformations | Cancer
Journal Article
Journal Article
Cancer Letters, ISSN 0304-3835, 2015, Volume 371, Issue 1, pp. 90 - 98
Highlights • CD44 expression is significantly increased in individuals whose gastric lesions progressed along the gastric precancerous cascade. • CD44 is... 
Hematology, Oncology and Palliative Medicine | Inflammation | Gastric cancer | CD44 | Gastritis | INTESTINAL METAPLASIA | TRANSENDOTHELIAL MIGRATION | IMMATURE MYELOID CELLS | GAMMA-INTERFERON | POLYPEPTIDE-EXPRESSING METAPLASIA | GENE POLYMORPHISMS | EPITHELIAL-CELLS | ONCOLOGY | AFRICAN-AMERICANS | UP-REGULATION | INFLAMMATORY MEDIATORS | Chemotaxis, Leukocyte | Helicobacter pylori - immunology | Gastric Mucosa - microbiology | Humans | Helicobacter pylori - pathogenicity | Stomach Neoplasms - metabolism | Gastric Mucosa - pathology | Precancerous Conditions - metabolism | Interferon-gamma - metabolism | Gastric Mucosa - metabolism | Neutrophil Infiltration | Gastritis, Atrophic - genetics | Gastritis, Atrophic - immunology | Precancerous Conditions - diagnosis | Time Factors | Hyaluronan Receptors - metabolism | Antigens, Ly - metabolism | Female | Helicobacter Infections - metabolism | Helicobacter Infections - diagnosis | Neutrophils - metabolism | Disease Models, Animal | Stomach Neoplasms - genetics | Stomach Neoplasms - diagnosis | Gastritis, Atrophic - microbiology | Signal Transduction | Cells, Cultured | Neutrophils - immunology | Macrophages, Peritoneal - immunology | Helicobacter Infections - immunology | Gastritis, Atrophic - metabolism | Helicobacter Infections - genetics | Gastritis, Atrophic - diagnosis | Hyaluronan Receptors - genetics | Precancerous Conditions - genetics | Disease Progression | Mice, Knockout | Stomach Neoplasms - immunology | Gastric Mucosa - immunology | Stomach Neoplasms - microbiology | Animals | Precancerous Conditions - immunology | Hyaluronan Receptors - immunology | Precancerous Conditions - microbiology | Macrophages, Peritoneal - metabolism | Helicobacter Infections - microbiology | Helicobacter pylori | Medical research | Disease | Biopsy | Migration | Ligands | Infections | Stomach cancer | gastric cancer | gastritis
Journal Article