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myocilin (258) 258
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olfactomedin (37) 37
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Experimental Eye Research, ISSN 0014-4835, 12/2014, Volume 129, pp. 1 - 4
Retinal Pigment Epithelial cells (RPE) express both GPR143 and myocilin, which interact in a signal transduction-dependent manner. In heterologous systems,... 
Pigment | Endocytosis | GPR143 | Myocilin | Exosome | G-protein-coupled receptor | Retinal pigment epithelium
Journal Article
Journal Article
Biochemistry, ISSN 0006-2960, 04/2019, Volume 58, Issue 13, pp. 1718 - 1727
Mutations in myocilin, predominantly within its olfactomedin (OLF) domain, are causative for the heritable form of open angle glaucoma in humans. Surprisingly,... 
FIBRIL FORMATION | OPEN-ANGLE GLAUCOMA | IN-VITRO | TRABECULAR MESHWORK | ALZHEIMERS-DISEASE | ER STRESS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ISLET AMYLOID POLYPEPTIDE | MOLECULAR-DYNAMICS SIMULATIONS | MUTATED MOUSE | MYOCILIN
Journal Article
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, ISSN 0146-0404, 05/2019, Volume 60, Issue 6, pp. 2034 - 2037
Antibodies are key reagents used in vision research, indeed across biomedical research, but they often do not reveal the whole story about a sample. It is... 
NON-SECRETION | PROTEIN | TRABECULAR MESHWORK | ER STRESS | post translational modification | CLEAVAGE | misfolding | IN-VITRO | STRUCTURAL BASIS | RETICULUM STRESS | OPHTHALMOLOGY | antibodies | MUTANT MYOCILIN | OLFACTOMEDIN DOMAIN
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2018, Volume 13, Issue 11, pp. e0206801 - e0206801
Myocilin (MYOC) is the gene with mutations most common in glaucoma. In the eye, MYOC is in trabecular meshwork, ciliary body, and retina. Other tissues with... 
OPEN-ANGLE GLAUCOMA | PROTEIN | GENE | ER STRESS | MULTIDISCIPLINARY SCIENCES | TIGR | REGULATORY PHOSPHORYLATION SITE | M-BAND | MUTATIONS | IDENTIFICATION | CREATINE-KINASE | Trabecular Meshwork - ultrastructure | Cytoskeletal Proteins - genetics | Glaucoma, Open-Angle - genetics | Humans | Glycoproteins - metabolism | Glaucoma, Open-Angle - pathology | Male | Muscle, Skeletal - metabolism | Intraocular Pressure - genetics | Mice, Mutant Strains | Sarcomeres - genetics | Myocardium - metabolism | Cytoskeletal Proteins - metabolism | Female | Glaucoma, Open-Angle - metabolism | Eye Proteins - genetics | Disease Models, Animal | Glycoproteins - genetics | Recombinant Proteins - metabolism | Microscopy, Electron, Transmission | Gene Expression | Sarcomeres - metabolism | Muscle, Skeletal - ultrastructure | Mutant Proteins - genetics | Mice, Transgenic | Mutant Proteins - metabolism | Recombinant Proteins - genetics | Sarcomeres - ultrastructure | Phenotype | Animals | Eye Proteins - metabolism | Trabecular Meshwork - metabolism | Mice | Mutation | Genetically modified mice | Gene mutations | Muscles | Physiological aspects | Research | Structure | Glaucoma | Biomedical research | Immunoprecipitation | Transcription | Creatine kinase | Retina | Electron micrographs | Creatine | Western blotting | Proteins | Lysates | Genotype & phenotype | Ultrastructure | Transgenic animals | Rodents | Gastrocnemius muscle | Age | Binding | Phenotypes | Cardiac muscle | Transgenic mice | Skeletal muscle | Pathology | Musculoskeletal system | Sarcomeres | Intraocular pressure | Index Medicus
Journal Article
International Journal of Pharma and Bio Sciences, 2015, Volume 6, Issue 3, pp. B992 - B1005
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 09/2011, Volume 121, Issue 9, pp. 3542 - 3553
Journal Article
Clinica Chimica Acta, ISSN 0009-8981, 08/2019, Volume 495, pp. 529 - 537
Since tears are a biological fluid, they have a potential diagnostic value for ophthalmic diseases. The aim of this study was to compare tear supernatants and... 
miRNA | Small extracellular vesicles | Bacterial DNA | Tears | CELLS | CYTOKINES | EXOSOME ISOLATION | CHEMOKINES | MICRORNAS | MYOCILIN | GENES | MEDICAL LABORATORY TECHNOLOGY | CD24 | HUMOR | EXPRESSION | Glaucoma | Medicine, Experimental | Medical research | MicroRNA | Transmission electron microscopes | Analysis
Journal Article
EXPERIMENTAL NEUROLOGY, ISSN 0014-4886, 11/2014, Volume 261, pp. 802 - 811
Olfactomedin 2 (Olfm2) is a secretory glycoprotein belonging to the family of olfactomedin domain-containing proteins. A previous study has shown that a... 
NERVOUS-SYSTEM | GERM-LINE | Neurobiology | Anxiety behavior | Olfactory defects | Retina | NEUROSCIENCES | MYOCILIN | AMPA receptor | OPEN-ANGLE GLAUCOMA | Mouse | GENE | INTERACTS | IN-VIVO | Olfactomedin 2 | MUTATIONS | PROTEINS
Journal Article
Experimental Eye Research, ISSN 0014-4835, 08/2018, Volume 173, pp. 109 - 112
Journal Article
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, ISSN 1422-0067, 05/2019, Volume 20, Issue 10, p. 2526
The house swine (Sus scrofa domestica Linnaeus 1758) is an important model organism regarding the study of neurodegenerative diseases, especially ocular... 
ANTIBODIES | MYOCILIN EXPRESSION | CELLS | LOCALIZATION | proteomics | glaucoma | BIOCHEMISTRY & MOLECULAR BIOLOGY | AQUEOUS-HUMOR | CHEMISTRY, MULTIDISCIPLINARY | trabecular meshwork | NEURAL CREST ORIGIN | model organism | mass spectrometry | EXTRACELLULAR-MATRIX | CRYSTALLIN | PROTEINS | Sus scrofa
Journal Article
Journal Article