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1. Full Text Evidence for a Stem Cell Hierarchy in the Adult Human Breast
by René Villadsen and Agla J. Fridriksdottir and Lone Rønnov-Jessen and Thorarinn Gudjonsson and Fritz Rank and Mark A. LaBarge and Mina J. Bissell and Ole W. Petersen
The Journal of Cell Biology, ISSN 0021-9525, 4/2007, Volume 177, Issue 1, pp. 87 - 101
Cellular pathways that contribute to adult human mammary gland architecture and lineages have not been previously described. In this study, we identify a... 
Keratins | Epithelial cells | Breasts | Stem cells | Cell lines | Multipotent stem cells | Cultured cells | Mammary glands | Progenitor cells | Cells | HUMAN MAMMARY-GLAND | PROGENITOR CELLS | MYOEPITHELIAL CELLS | NEOPLASTIC BREAST | DIFFERENTIAL EXPRESSION | HUMAN PROSTATE | EPITHELIAL-CELLS | INTEGRIN SUBUNITS | MONOCLONAL-ANTIBODIES | STROMAL CELLS | CELL BIOLOGY | Biomarkers - metabolism | Cell Line | Mammary Glands, Human - cytology | Transduction, Genetic | Breast - cytology | Humans | Repressor Proteins - genetics | Papillomavirus E7 Proteins | Stem Cells - metabolism | Breast - metabolism | Cell Lineage | Stem Cells - classification | Keratins - metabolism | Female | Oncogene Proteins, Viral - genetics | Cell Differentiation | Cell culture | Cell growth | Adults | Glycoproteins | Index Medicus
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2. Full Text Cell hierarchy and lineage commitment in the bovine mammary gland
by Rauner, Gat and Barash, Itamar
PLoS ONE, ISSN 1932-6203, 01/2012, Volume 7, Issue 1, pp. e30113 - e30113
The bovine mammary gland is a favorable organ for studying mammary cell hierarchy due to its robust milk-production capabilities that reflect the adaptation of... 
EPITHELIAL STEM-CELLS | ADULT HUMAN BREAST | PROGENITOR CELLS | SIGNALING PATHWAY CONTROLS | MYOEPITHELIAL CELLS | FAT PAD | SERIAL TRANSPLANTATION | MULTIDISCIPLINARY SCIENCES | STEM/PROGENITOR CELLS | FUNCTIONAL-CHARACTERIZATION | TEMPLATE DNA STRANDS | Biomarkers - metabolism | CD24 Antigen - metabolism | Cell Count | Humans | Multipotent Stem Cells - metabolism | Cells, Cultured | Gene Expression Regulation | Mammary Glands, Animal - cytology | Cell Lineage | Integrin alpha6 - metabolism | Animals | Mammary Glands, Animal - metabolism | Cattle | Models, Biological | Multipotent Stem Cells - cytology | Epithelial Cells - enzymology | Fluorescent Antibody Technique | Cell Aggregation | Female | Clone Cells | Colony-Forming Units Assay | Epithelial Cells - cytology | Aldehyde Dehydrogenase - metabolism | Gene expression | Analysis | Genes | Stem cells | Cell culture | Senescence | Populations | Breastfeeding & lactation | Propagation | Epithelial cells | Zoology | Breasts | Hormones | Cell surface | Rodents | Population | Extracellular matrix | Jagged1 protein | Mammary gland | Localization | Growth factors | Colonies | Markers | Animal sciences | Basal cells | Breast cancer | Mammals | Cell number | Surface markers | Index Medicus
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3. Full Text Proof of region-specific multipotent progenitors in human breast epithelia
by Fridriksdottir, Agla J and Villadsen, René and Morsing, Mikkel and Klitgaard, Marie Christine and Kim, Jiyoung and Petersen, Ole William and Rønnov-Jessen, Lone
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2017, Volume 114, Issue 47, pp. E10102 - E10111
The human breast parenchyma consists of collecting ducts and terminal duct lobular units (TDLUs). The TDLU is the site of origin of most breast cancers. The... 
Breast | Myoepithelial cell | Progenitors | Stem cell | CANCER RISK | GROUND-STATE | MULTIDISCIPLINARY SCIENCES | MAMMARY STEM-CELLS | TUMORS | progenitors | stem cell | myoepithelial cell | DIFFERENTIATION | MONOCLONAL-ANTIBODIES | breast | EXPRESSION | IMMORTALIZATION | MYOEPITHELIAL-CELL | GLAND | Myoepithelioma - metabolism | Epithelial Cells - metabolism | Prognosis | Humans | Middle Aged | Multipotent Stem Cells - metabolism | Mammary Glands, Human - metabolism | Antigens, CD - genetics | Myoepithelioma - pathology | Antigens, CD - metabolism | Cell Transformation, Neoplastic - genetics | Adult | Female | Cell Differentiation | Cell Culture Techniques | Epithelial Cells - cytology | Biomarkers - metabolism | Myoepithelioma - diagnosis | Mammary Glands, Human - cytology | Gene Expression | Muscle Cells - metabolism | Organ Specificity | Cell Transformation, Neoplastic - metabolism | Myoepithelioma - genetics | Muscle Cells - cytology | Keratin-19 - genetics | Multipotent Stem Cells - cytology | Adolescent | Primary Cell Culture | Cell Transformation, Neoplastic - pathology | Keratin-19 - metabolism | Breast cancer | Medical examination | Epithelium | Health aspects | Risk factors | Stem cells | Morphogenesis | Cell culture | Preservation | Ducts | Breasts | Parenchyma | Cancer | Index Medicus | Biological Sciences | PNAS Plus
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4. Full Text Evaluation of MCF10A as a reliable model for normal human mammary epithelial cells
by Qu, Ying and Han, Bingchen and Yu, Yi and Yao, Weiwu and Bose, Shikha and Karlan, Beth Y and Giuliano, Armando E and Cui, Xiaojiang
PLoS ONE, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, pp. e0131285 - e0131285
Breast cancer is the most common cancer in women and a leading cause of cancer-related deaths for women worldwide. Various cell models have been developed to... 
BREAST-CANCER | MYOEPITHELIAL CELLS | MORPHOGENESIS | IN-VITRO | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | MARKERS | PROLIFERATION | GLAND | LINES | CANCER STEM-CELLS | Milk Proteins - analysis | Epithelial Cells - chemistry | Epithelial Cells - drug effects | Receptors, Estrogen - analysis | Stem Cells - cytology | Membrane Proteins - analysis | Cell Line - cytology | Receptors, Progesterone - analysis | Cell Line - drug effects | Keratins - analysis | Laminin | Cell Shape | Female | Cell Culture Techniques | Epithelial Cells - cytology | Proteoglycans | Breast - cytology | Biomarkers - analysis | Collagen Type I | Cell Line - chemistry | Cell Adhesion | Stem Cells - chemistry | Vimentin - analysis | Phenotype | Animals | Intercellular Signaling Peptides and Proteins - pharmacology | Collagen | Culture Media - pharmacology | Drug Combinations | Immunohistochemistry | Cell culture | Transformation | Collagen (type I) | Physicians | Epithelial cells | Staining | Embedding | Kinases | Sectioning | Metastases | Proteins | Suspension culture | Casein | Lactalbumin | Rodents | Tumorigenesis | Mammary gland | Milk | Markers | Breast cancer | Transformations (mathematics) | Breast | Immunofluorescence | Cancer | Index Medicus
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5. Full Text Clear Cell Myoepithelial Carcinoma of Salivary Glands Showing EWSR1 Rearrangement: Molecular Analysis of 94 Salivary Gland Carcinomas With Prominent Clear Cell Component
by Skálová, Alena and Weinreb, Ilan and Hyrcza, Martin and Simpson, Roderick H.W and Laco, Jan and Agaimy, Abbas and Vazmitel, Marina and Majewska, Hanna and Vanecek, Tomas and Talarčik, Peter and Manajlovic, Spomenka and Losito, Simona N and Šteiner, Petr and Klimkova, Adela and Michal, Michal
The American Journal of Surgical Pathology, ISSN 0147-5185, 03/2015, Volume 39, Issue 3, pp. 338 - 348
This study examines the presence of the EWSR1 rearrangement in a variety of clear cell salivary gland carcinomas with myoepithelial differentiation. A total of... 
salivary gland | clear cell myoepithelial carcinoma | EWSR1 rearrangement | SURGERY | TRANSLOCATION | FUSION | EWSR1-CREB1 | CHN | PATHOLOGY | SOFT-TISSUE | TUMORS | MOLECULAR ANALYSIS | GENE | SARCOMA | Adenoma, Pleomorphic - genetics | Immunohistochemistry | Myoepithelioma - mortality | Predictive Value of Tests | RNA-Binding Proteins - genetics | Salivary Gland Neoplasms - mortality | Salivary Gland Neoplasms - genetics | Humans | Middle Aged | Carcinoma - mortality | Myoepithelioma - secondary | Male | Adenoma, Pleomorphic - therapy | Carcinoma - chemistry | Necrosis | Time Factors | Aged, 80 and over | Myoepithelioma - chemistry | Adult | Female | Carcinoma - secondary | Calmodulin-Binding Proteins - genetics | Genetic Predisposition to Disease | Myoepithelioma - therapy | Biomarkers, Tumor - analysis | Neoplasm Recurrence, Local | In Situ Hybridization, Fluorescence | Treatment Outcome | Lymphatic Metastasis | Adenoma, Pleomorphic - mortality | Myoepithelioma - genetics | Salivary Gland Neoplasms - chemistry | Adenoma, Pleomorphic - chemistry | Disease-Free Survival | Phenotype | Adenoma, Pleomorphic - pathology | Gene Rearrangement | Salivary Gland Neoplasms - therapy | Carcinoma - genetics | Carcinoma - therapy | Aged | Biomarkers, Tumor - genetics | Salivary Gland Neoplasms - pathology | RNA-Binding Protein EWS | Index Medicus
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6. Full Text IL-25 causes apoptosis of IL-25R-expressing breast cancer cells without toxicity to nonmalignant cells
by Furuta, Saori and Jeng, Yung-Ming and Zhou, Longen and Huang, Lan and Kuhn, Irene and Bissell, Mina J and Lee, Wen-Hwa
Science Translational Medicine, ISSN 1946-6234, 04/2011, Volume 3, Issue 78, pp. 78ra31 - 78ra31
As cells differentiate into tissues, the microenvironment that surrounds these cells must cooperate so that properly organized, growth-controlled tissues are... 
TNF RECEPTOR | IL-17E | MEDICINE, RESEARCH & EXPERIMENTAL | MYOEPITHELIAL CELLS | EPITHELIAL-CELLS | MECHANISM | INTERLEUKIN-17 FAMILY | VASCULATURE | IN-VIVO | PHENOTYPE | PROLIFERATION | CELL BIOLOGY | Fas-Associated Death Domain Protein - genetics | Immunohistochemistry | Cell Line | Immunoprecipitation | Apoptosis - drug effects | Humans | Fas-Associated Death Domain Protein - metabolism | Apoptosis - genetics | Interleukin-17 - pharmacology | Receptors, Interleukin - genetics | Breast Neoplasms - metabolism | TNF Receptor-Associated Death Domain Protein - genetics | Receptors, Interleukin - metabolism | Tandem Mass Spectrometry | Breast Neoplasms - genetics | Cell Line, Tumor | Chromatography, Liquid | Female | RNA, Small Interfering | In Vitro Techniques | TNF Receptor-Associated Death Domain Protein - metabolism | Index Medicus
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7. Full Text Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function
by Sarper, Muge and Allen, Michael D and Gomm, Jenny and Haywood, Linda and Decock, Julie and Thirkettle, Sally and Ustaoglu, Ahsen and Sarker, Shah-Jalal and Marshall, John and Edwards, Dylan R and Jones, J Louise
Breast cancer research : BCR, 03/2017, Volume 19, Issue 1, p. 33
Normal myoepithelial cells (MECs) play an important tumour-suppressor role in the breast but display an altered phenotype in ductal carcinoma in situ (DCIS),... 
Carcinoma, Ductal, Breast - genetics | Immunohistochemistry | Epithelial Cells - metabolism | Humans | Carcinoma, Intraductal, Noninfiltrating - metabolism | Carcinoma, Intraductal, Noninfiltrating - genetics | Biomarkers, Tumor | Gene Knockdown Techniques | Matrix Metalloproteinase 9 - metabolism | Cell Transformation, Neoplastic - genetics | Matrix Metalloproteinase 8 - metabolism | Proteolysis | Carcinoma, Ductal, Breast - pathology | Female | Integrin alpha6beta4 - metabolism | Carcinoma, Ductal, Breast - metabolism | Matrix Metalloproteinase 8 - genetics | Gene Expression | Paracrine Communication | Signal Transduction | Cell Survival | Cell Adhesion | Cell Transformation, Neoplastic - metabolism | Matrix Metalloproteinase 8 - deficiency | Protein Transport | Carcinoma, Intraductal, Noninfiltrating - pathology | Cell Line, Tumor | Transforming Growth Factor beta - metabolism | Cell Line, Transformed | Cell Movement
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8. Full Text Myoepithelial Cells of Submucosal Glands Can Function as Reserve Stem Cells to Regenerate Airways after Injury
by Tata, Purushothama Rao and Tata, Aleksandra and Kobayashi, Yoshihiko and Chow, Ryan D and Tran, Jasmine and Desai, Avani and Massri, Abdull J and McCord, Timothy J and Gunn, Michael Dee
Cell Stem Cell, ISSN 1934-5909, 05/2018, Volume 22, Issue 5, pp. 668 - 683.e6
Cells demonstrate plasticity following injury, but the extent of this phenomenon and the cellular mechanisms involved remain underexplored. Using single-cell... 
single-cell RNA sequencing | myoepithelial cells | cellular plasticity | multipotent stem cells | airway regeneration | reserve stem cells | submucosal gland stem cells | PROGENITOR CELLS | LUNG | EPITHELIAL PROGENITOR | MULTIPOTENT | TRACHEAL BASAL-CELLS | CHLORINE GAS | IN-VIVO | NICHE | MAMMARY-GLAND | PLASTICITY | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Index Medicus | Myoepithelial cells | Cellular plasticity | Airway regeneration | Multipotent stem cells | Single cell RNA sequencing
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9. Full Text Submucosal Gland Myoepithelial Cells Are Reserve Stem Cells That Can Regenerate Mouse Tracheal Epithelium
by Lynch, Thomas J and Anderson, Preston J and Rotti, Pavana G and Tyler, Scott R and Crooke, Adrianne K and Choi, Soon H and Montoro, Daniel T and Silverman, Carolyn L and Shahin, Weam and Zhao, Rui and Jensen-Cody, Chandler W and Adamcakova-Dodd, Andrea and Evans, T. Idil Apak and Xie, Weiliang and Zhang, Yulong and Mou, Hongmei and Herring, B. Paul and Thorne, Peter S and Rajagopal, Jayaraj and Yeaman, Charles and Parekh, Kalpaj R and Engelhardt, John F
Cell Stem Cell, ISSN 1934-5909, 05/2018, Volume 22, Issue 5, pp. 653 - 667.e5
The mouse trachea is thought to contain two distinct stem cell compartments that contribute to airway repair—basal cells in the surface airway epithelium (SAE)... 
lymphoid enhancer-binding factor-1 | airway basal cell | lineage-trace | multipotency | myoepithelial cell | injury repair | LEF1 | plasticity | PROGENITOR CELLS | LUNG | MORPHOGENESIS | TRANSCRIPTION | LEF-1 PROMOTER | AIRWAY EPITHELIUM | EXPRESSION | ADULT | MAMMARY-GLAND | PLASTICITY | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Index Medicus
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10. Full Text Differentiation dynamics of mammary epithelial stem cells from Korean holstein dairy cattle under ECM-free conditions
by Sharma, Neelesh and Kim, Jeong Hyun and Sodhi, Simrinder Singh and Luong, Do Huynh and Kim, Sung-Woo and Oh, Sung Jong and Jeong, Dong Kee
Journal of Biomolecular Structure and Dynamics, ISSN 0739-1102, 12/2015, Volume 33, Issue 12, pp. 2633 - 2654
The "stem cells" are commonly defined as "cells capable of self-renewal through replication and differentiating into specific lineages". The mammary gland... 
matrigel | luminal cells | KHMESCs | myoepithelial cells | differentiation dynamics | MILK-PRODUCTION | FUNCTIONAL-DIFFERENTIATION | ALDEHYDE DEHYDROGENASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SELF-RENEWAL | GLAND DEVELOPMENT | IN-VITRO | BIOPHYSICS | MESSENGER-RNA | GROWTH | STEM/PROGENITOR CELLS | CASEIN GENE-EXPRESSION | Lactation | Extracellular Matrix - metabolism | Stem Cells - cytology | Stem Cells - metabolism | Cell Culture Techniques - methods | Cell Differentiation - genetics | Laminin | Cattle | Female | Epithelial Cells - cytology | Cell Differentiation - physiology | Cell Lineage - genetics | Milk Proteins - metabolism | Microscopy, Electron, Transmission | Cell Proliferation - genetics | Gene Expression | Pluripotent Stem Cells - cytology | Proteoglycans | Cell Proliferation - physiology | Cells, Cultured | Milk Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Stem Cells - ultrastructure | Cell Lineage - physiology | Mammary Glands, Animal - cytology | Pluripotent Stem Cells - metabolism | Animals | Collagen | Kinetics | Drug Combinations | Index Medicus
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11. Full Text Collective Epithelial Migration and Cell Rearrangements Drive Mammary Branching Morphogenesis
by Ewald, Andrew J and Brenot, Audrey and Duong, Myhanh and Chan, Bianca S and Werb, Zena
Developmental Cell, ISSN 1534-5807, 04/2008, Volume 14, Issue 4, pp. 570 - 581
Epithelial organs are built through the movement of groups of interconnected cells. We observed cells in elongating mammary ducts reorganize into a... 
DEVBIO | KEY STAGES | MYOEPITHELIAL CELLS | ADHESION | URETERAL BUD | POLARITY | GROWTH | DEVELOPMENTAL BIOLOGY | MODEL | DIFFERENTIATION | DUCTAL MORPHOGENESIS | GLAND DEVELOPMENT | CELL BIOLOGY | Organoids - physiology | Cell Polarity | Cell Proliferation | Actins - metabolism | Myosin-Light-Chain Kinase - antagonists & inhibitors | Recombinant Fusion Proteins - metabolism | Cell Movement - physiology | rho-Associated Kinases - antagonists & inhibitors | Mammary Glands, Animal - growth & development | Epithelial Cells - physiology | rho-Associated Kinases - metabolism | Epithelium - anatomy & histology | Female | Epithelial Cells - cytology | Biomarkers - metabolism | Cell Surface Extensions - ultrastructure | Enzyme Inhibitors - metabolism | Cell Surface Extensions - metabolism | Myosin-Light-Chain Kinase - metabolism | Cells, Cultured | Organoids - cytology | Mice, Transgenic | Disease Progression | Mammary Glands, Animal - cytology | Mammary Neoplasms, Animal - pathology | Animals | Mammary Neoplasms, Animal - metabolism | rac1 GTP-Binding Protein - antagonists & inhibitors | Recombinant Fusion Proteins - genetics | Signal Transduction - physiology | Epithelium - physiology | Mice | Morphogenesis - physiology | rac1 GTP-Binding Protein - metabolism | Index Medicus
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12. Full Text Growth and differentiation of progenitor/stem cells derived from the human mammary gland
by Clayton, Helen and Titley, Ian and Vivanco, Maria dM
Experimental Cell Research, ISSN 0014-4827, 07/2004, Volume 297, Issue 2, pp. 444 - 460
Estrogen is necessary for the full development of the mammary gland and it is also involved in breast cancer development. We set out to identify and... 
Epithelial markers | Human mammary gland | Differentiation | Estrogen | Stem cells | Side population | ADULT HUMAN BREAST | stem cells | estrogen | STEM-CELLS | differentiation | ER-BETA | human mammary gland | CELL BIOLOGY | side population | MYOEPITHELIAL CELLS | IN-VITRO | EPITHELIAL-CELLS | ONCOLOGY | ESTROGEN-RECEPTOR-ALPHA | GENE-EXPRESSION | epithelial markers | CANCER RESISTANCE PROTEIN | HEMATOPOIETIC STEM | ATP Binding Cassette Transporter, Sub-Family G, Member 2 | NIH 3T3 Cells | Breast - cytology | Humans | Cells, Cultured | Stem Cells - cytology | Neoplasm Proteins - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Stem Cells - metabolism | Mammary Glands, Animal - cytology | Cell Lineage | Keratins - analysis | Animals | Flow Cytometry | Models, Biological | Cell Division | ATP-Binding Cassette Transporters - metabolism | Biomarkers | Female | Cell Differentiation | Fibroblasts - cytology | Mice | Epithelial Cells - cytology | Fluorescent Antibody Technique, Indirect | Index Medicus
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