X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
mypt1 (103) 103
phosphorylation (68) 68
index medicus (58) 58
animals (55) 55
myosin phosphatase (51) 51
myosin (38) 38
rho-kinase (33) 33
ca2+ sensitization (30) 30
humans (30) 30
myosin-light-chain phosphatase - metabolism (29) 29
biochemistry & molecular biology (28) 28
pharmacology & pharmacy (28) 28
cell biology (26) 26
light-chain phosphatase (26) 26
rho-associated kinase (26) 26
muscle proteins (23) 23
phosphatases (23) 23
smooth muscle (23) 23
cpi-17 (22) 22
male (21) 21
rats (21) 21
smooth-muscle contraction (21) 21
myosin light chains - metabolism (20) 20
signal-transduction (20) 20
fluoride (17) 17
mice (17) 17
myosin-light-chain phosphatase - genetics (17) 17
physiology (17) 17
activation (16) 16
article (15) 15
erk1/2 (15) 15
phorbol ester (15) 15
rats, sprague-dawley (15) 15
phosphatase (14) 14
protein phosphatase 1 - metabolism (14) 14
protein-kinase (14) 14
proteins (14) 14
rho kinase (14) 14
biophysics (13) 13
integrin-linked kinase (13) 13
smooth-muscle (13) 13
cells, cultured (12) 12
muscle proteins - metabolism (12) 12
muscle, smooth, vascular - drug effects (12) 12
phosphoproteins - metabolism (12) 12
phosphorylation - drug effects (12) 12
rhoa (12) 12
rho-associated kinases - metabolism (11) 11
signal transduction (11) 11
calcium sensitization (10) 10
contraction (10) 10
muscle contraction (10) 10
original (10) 10
binding (9) 9
calcium - metabolism (9) 9
cells (9) 9
in vitro techniques (9) 9
in-vivo (9) 9
inhibition (9) 9
muscle contraction - drug effects (9) 9
nitric-oxide (9) 9
original article (9) 9
phosphoprotein phosphatases - metabolism (9) 9
protein kinase inhibitors - pharmacology (9) 9
protein kinases (9) 9
protein phosphatase (9) 9
protein phosphatase-1 (9) 9
sensitization (9) 9
calcium (8) 8
erk1 (8) 8
hypertension (8) 8
kinases (8) 8
muscle, smooth, vascular - physiology (8) 8
myosin light chain phosphatase (8) 8
neurosciences (8) 8
protein-serine-threonine kinases - metabolism (8) 8
rho-associated kinases - antagonists & inhibitors (8) 8
sensitivity (8) 8
signal transduction - drug effects (8) 8
vascular smooth-muscle (8) 8
vasorelaxation (8) 8
aorta, thoracic - drug effects (7) 7
elméleti orvostudományok (7) 7
female (7) 7
kinase (7) 7
life sciences (7) 7
macromolecular substances (7) 7
muscle contraction - physiology (7) 7
muscle, smooth, vascular - metabolism (7) 7
myosin-light-chain kinase - metabolism (7) 7
orvostudományok (7) 7
peripheral vascular disease (7) 7
protein kinase c (7) 7
protein phosphatase 1 (7) 7
research article (7) 7
rhoa gtp-binding protein - metabolism (7) 7
targeting subunit (7) 7
vascular smooth muscle (7) 7
zebrafish (7) 7
amino acid sequence (6) 6
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Cell Cycle, ISSN 1538-4101, 10/2019, Volume 18, Issue 20, pp. 2651 - 2659
Checkpoint kinase 2 (Chk2) is a pivotal effector kinase in the DNA damage response, with an emerging role in mitotic chromosome segregation. In this study, we... 
Phosphoprotein phosphatase 1β (PP1β) | Plk1 | Chk2 | centrosome | MYPT1
Journal Article
Biology of Reproduction, ISSN 0006-3363, 05/2016, Volume 94, Issue 5
Placental vascular dysfunction has been linked to insufficiency/deficiency of maternal vitamin D levels during pregnancy. In contrast, sufficient maternal... 
placenta | VSMC contractility | vitamin D | MYPT1 | pregnancy
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 12/2018, Volume 315, Issue 6, pp. G921 - G931
It has been known that activation of protease-activated receptors (PARs) affects gastrointestinal motility. In this study, we tested the effects of PAR... 
Protein kinase C | CPI-17 | Protease-activated receptor | Rho kinase | SK channels | MYPT1
Journal Article
Cardiovascular Research, ISSN 0008-6363, 07/2011, Volume 91, Issue 1, pp. 162 - 170
Journal Article
Nitric Oxide - Biology and Chemistry, ISSN 1089-8603, 04/2019, Volume 85, pp. 54 - 60
Rho-kinase activity is a key regulator in the maintenance of corporal vasoconstriction and penile detumescense. Also, importance of L-cysteine/H S pathway in... 
Mouse corpus cavernosum | H2S level | L-cysteine/H2S pathway | MYPT1 activity | RhoA/Rho-kinase
Journal Article
Neurogastroenterology and Motility, ISSN 1350-1925, 12/2011, Volume 23, Issue 12, pp. 1111 - 1122
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 07/2015, Volume 210, pp. 189 - 197
The intestinal epithelium functions to effectively restrict the causal uptake of luminal contents but has been demonstrated to transiently increase... 
Tight junction function | Myosin light chain phosphatase | Protein–protein interactions | Cell penetrating peptide | Paracellular transport | Insulin delivery | Abbreviations CPP Cell Penetrating Peptide | pMLC Phosphorylated myosin light chain | SPPS Solid phase peptide synthesis | TJ Tight junction | MLC Myosin light chain | PK/PD Pharmacokinetics/pharmacodynamics | SC Subcutaneous | MLCK Myosin light chain kinase | FD Fluorescent dextran | DAPI 4′ 6-diamidino-2-phenylindole | PBS Phosphate buffer saline | PKC Protein kinase C | FMC 9-fluorenylmethyloxycarbonyl | MLCP Myosin light chain phosphatase | ILI Intraluminal injection | MTS 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium | MYPT1 Myosin phosphatase target subunit | ABSORPTION ENHANCEMENT | PROTEIN PHOSPHATASE-1 | RHO-ASSOCIATED KINASE | MEMBRANE-PERMEANT PEPTIDE | MECHANISMS | CHEMISTRY, MULTIDISCIPLINARY | Protein-protein interactions | INTESTINAL-ABSORPTION | TIGHT JUNCTIONS | SMOOTH-MUSCLE | IN-VITRO | PHARMACOLOGY & PHARMACY | SODIUM CAPRATE | Caco-2 Cells | Insulin - pharmacology | Phosphorylation | Blood Glucose - analysis | Rats, Wistar | Humans | Insulin - administration & dosage | Male | Myosin-Light-Chain Phosphatase | Animals | Biological Transport | Myosin Light Chains - metabolism | Oligopeptides - administration & dosage | Oligopeptides - pharmacology | Phosphoprotein Phosphatases | Dextran | Biological products | Peptides | Blood sugar | Myosin | Permeability | Muscle proteins | Insulin | Phosphatases | Protein kinases | Index Medicus | PKC, Protein kinase C | MLC, Myosin light chain | pMLC, Phosphorylated myosin light chain | pharmacodynamics | TJ, Tight junction | PD, Pharmacokinetics | MTS, 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium | MLCK, Myosin light chain kinase | DAPI, 4′,6-diamidino-2-phenylindole | PBS, Phosphate buffer saline | MLCP, Myosin light chain phosphatase | MYPT1, Myosin phosphatase target subunit | CPP, Cell Penetrating Peptide | SC, Subcutaneous | FD, Fluorescent dextran | ILI, Intraluminal injection | FMC, 9-fluorenylmethyloxycarbonyl | SPPS, Solid phase peptide synthesis
Journal Article
Biomolecules & Therapeutics(구 응용약물학회지), ISSN 1976-9148, 2018, Volume 26, Issue 2, pp. 139 - 145
The present study was undertaken to investigate the influence of hypothermia on endothelium-independent vascular smooth muscle contractility and to determine... 
Rho-kinase | fluoride | ERK1/2 | hypothermia | phorbol ester | MYPT1
Journal Article
Biomolecules & Therapeutics(구 응용약물학회지), ISSN 1976-9148, 2018, Volume 26, Issue 4, pp. 374 - 379
In this study, we investigated the effects of pelargonidin, an anthocyanidin found in many fruits and vegetables, on endotheliumindependent vascular... 
Rho-kinase | ERK1/2 | Fluoride | Phorbol ester | MYPT1 | Pelargonidin
Journal Article
by He, WQ and Qiao, YN and Peng, YJ and Zha, JM and Zhang, CH and Chen, C and Chen, CP and Wang, P and Yang, X and Li, CJ and Kamm, KE and Stull, JT and Zhu, MS
GASTROENTEROLOGY, ISSN 0016-5085, 06/2013, Volume 144, Issue 7, pp. 1456 - U233
BACKGROUND & AIMS: The regulatory subunit of myosin light chain phosphatase, MYPT1, has been proposed to control smooth muscle contractility by regulating... 
LIGHT-CHAIN KINASE | PROTEIN PHOSPHATASE-1 | CA2+ SENSITIZATION | Phosphorylation | SENSITIVITY | NONMUSCLE MYOSIN | FORCE | Development | MYPT1 GENE | GASTROENTEROLOGY & HEPATOLOGY | SMOOTH-MUSCLE CONTRACTION | Calcium Signaling | MYOSIN PHOSPHATASE | Mouse Model
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 09/2019, Volume 294, Issue 36, pp. 13280 - 13291
Transforming growth factor-beta membrane associated protein (TIMAP) is an endothelial cell (EC)-predominant PP1 regulatory subunit and a member of the myosin... 
SPECIFICITY | PHOSPHORYLATION | endothelial cell | angiogenesis | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | myosin phosphatase | MYPT1 | BARRIER | myosin | TARGETING SUBUNIT | DOCKING MOTIF | OKADAIC ACID | BETA | phosphoprotein phosphatase 1 (PP1) | SMOOTH-MUSCLE | inhibitor | STRUCTURAL BASIS | microcystin | Cell Biology
Journal Article
Biochemical Journal, ISSN 0264-6021, 01/2014, Volume 457, Issue 1, pp. 215 - 225
The related NUAK1 and NUAK2 are members of the AMPK (AMP-activated protein kinase) family of protein kinases that are activated by the LKB1 (liver kinase B1)... 
AMPK-related kinase 5 (ARK5) | AMP-activated protein kinase (AMPK) | Sucrose-non-fermenting protein kinase/AMPKrelated protein kinase (SNARK) | Liver kinase B1 (LKB1) | Kinase profiling | Kinase inhibitor | Myosin phosphate-targeting subunit 1(MYPT1) | CELLS | liver kinase B1 (LKB1) | PHOSPHORYLATION | ARK5 | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | sucrose-non-fermenting protein kinase/AMPK-related protein kinase (SNARK) | kinase inhibitor | INVASION | PATHWAY | ROLES | kinase profiling | AMPK | myosin phosphate-targeting subunit 1(MYPT1) | ASSOCIATION | EXPRESSION | Protein Kinases - genetics | Humans | Substrate Specificity | Heterocyclic Compounds, 4 or More Rings - pharmacology | Repressor Proteins - antagonists & inhibitors | HEK293 Cells | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Drug Evaluation, Preclinical | Protein-Serine-Threonine Kinases - metabolism | Protein-Serine-Threonine Kinases - physiology | Benzodiazepinones - pharmacology | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Repressor Proteins - genetics | Repressor Proteins - agonists | Pyrimidines - pharmacology | Enzyme Activation - drug effects | Cell Movement - drug effects | Tumor Suppressor Proteins - physiology | Animals | Anilides - pharmacology | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Neoplasms - pathology | ACC, acetyl-CoA carboxylase | AMPKrelated protein kinase (SNARK) | SIK, salt-induced kinase | NF-κB, nuclear factor κB | HEK, human embryonic kidney | AMPK, AMP-activated protein kinase | HA, haemagglutinin | BRSK, brain-specific kinase | sucrose-non-fermenting protein kinase | DMEM, Dulbecco’s modified Eagle’s medium | PP1, protein phosphatase 1 | MEF, mouse embryonic fibroblast | PEI, polyethylenimine | MARK, microtubule-affinity-regulating kinase | MYPT1, myosin phosphate-targeting subunit 1 | LKB1, liver kinase B1
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 43, pp. 16677 - 16686
Contractile force development of smooth muscle is controlled by balanced kinase and phosphatase activities toward the myosin regulatory light chain (RLC).... 
CATALYTIC SUBUNIT | DIPHOSPHORYLATION | MECHANISM | FORCE GENERATION | CONSTITUTIVE PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | MYPT1 | smooth muscle | myosin | protein phosphorylation | TARGETING SUBUNIT-1 PHOSPHORYLATION | protein phosphatase | muscle physiology | ROLES | PP1c | contraction | MYOSIN LIGHT-CHAIN | KINASE ACTIVATION | BINDING | Signal Transduction
Journal Article
Gene, ISSN 0378-1119, 10/2018, Volume 675, pp. 15 - 26
Myosin phosphatase is an evolutionarily conserved regulator of actomyosin contractility, comprised of a regulatory subunit (Mypt1), and a catalytic subunit... 
PP1 | Convergent extension | Gastrulation | Mypt1 | Splicing | Actomyosin | Zebrafish | Myosin phosphatase | ISOFORMS | LIGHT-CHAIN PHOSPHATASE | PHOSPHORYLATION | INTERACTING PROTEIN-KINASE | MORPHOGENESIS | CELL MOVEMENTS | GENES | GENETICS & HEREDITY | EXPRESSION | Embryonic development | Phosphatases | Gene mutations | Muscle proteins | Protein kinases | Myosin | Convergent Extension
Journal Article
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, ISSN 0193-1857, 12/2018, Volume 315, Issue 6, pp. G921 - G931
It has been known that activation of protease-activated receptors (PARs) affects gastrointestinal motility. In this study, we tested the effects of PAR... 
CA2+ SENSITIZATION | PHYSIOLOGY | Rho kinase | SK channels | MYPT1 | CPI-17 | INTERSTITIAL-CELLS | SIGNAL-TRANSDUCTION | VISCERAL PAIN | PHOSPHATASE TARGETING SUBUNIT | SMOOTH-MUSCLE | THROMBIN GENERATION | ALPHA-POSITIVE CELLS | protease-activated receptor | MOLECULAR-CLONING | GASTROENTEROLOGY & HEPATOLOGY | protein kinase C | MYOSIN PHOSPHATASE
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 07/2019, Volume 294, Issue 28, pp. 10846 - 10862
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2018, Volume 293, Issue 39, pp. 15152 - 15162
The protein Ser/Thr phosphatase PP1 catalyzes an important fraction of protein dephosphorylation events and forms highly specific holoenzymes through an... 
enzyme | SPLICING FACTORS | CATALYTIC SUBUNIT | REGULATORY SUBUNIT | SPECIFICITY | signal transduction | BIOCHEMISTRY & MOLECULAR BIOLOGY | MYPT1 | KINASE | IDENTIFICATION | PHOSPHORYLATION SITES | phosphoprotein phosphatase 1 (PP1) | NUCLEAR INHIBITOR | substrate specificity | phosphatase | PNUTS | NIPP1 | substrate mapping | RepoMan | REPO-MAN | Methods and Resources
Journal Article
No results were found for your search.

Cannot display more than 1000 results, please narrow the terms of your search.