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American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 09/2011, Volume 301, Issue 3, pp. C559 - C565
Deliu E, Tica AA, Motoc D, Brailoiu GC, Brailoiu E. Intracellular angiotensin II activates rat myometrium. Am J Physiol Cell Physiol 301: C559-C565, 2011.... 
Calcium imaging | Microinjection | Cytosolic calcium concentration | Endoplasmic reticulum | CYCLIC ADP-RIBOSE | PHYSIOLOGY | ANG-II | LIVER LYSOSOMES | RECEPTOR | microinjection | METABOLIC-CLEARANCE | BLOOD-PRESSURE | UTERINE | CELL BIOLOGY | SIGNAL-TRANSDUCTION | RENAL ENDOSOMES | SMOOTH-MUSCLE-CELLS | calcium imaging | cytosolic calcium concentration | endoplasmic reticulum | Myometrium - drug effects | Type C Phospholipases - metabolism | Brefeldin A - pharmacology | Angiotensin II Type 1 Receptor Blockers - pharmacology | Autophagy - drug effects | Endosomes - metabolism | Angiotensin II Type 2 Receptor Blockers - pharmacology | Macrocyclic Compounds - pharmacology | Saralasin - pharmacology | Endoplasmic Reticulum - drug effects | Estrenes - pharmacology | Myometrium - metabolism | Inositol 1,4,5-Trisphosphate Receptors - antagonists & inhibitors | Ryanodine - pharmacology | Angiotensin II - pharmacology | Pyridines - administration & dosage | Endocytosis - drug effects | Enzyme Inhibitors - pharmacology | Losartan - pharmacology | Saralasin - administration & dosage | Rats | Imidazoles - pharmacology | Piperazines - pharmacology | Rats, Sprague-Dawley | Receptor, Angiotensin, Type 2 - metabolism | Signal Transduction - drug effects | Calcium Signaling - drug effects | Models, Biological | Receptor, Angiotensin, Type 1 - metabolism | Oxazoles - pharmacology | Losartan - administration & dosage | Angiotensin II - administration & dosage | Calcium Signaling - physiology | Endoplasmic Reticulum - metabolism | Imidazoles - administration & dosage | Type C Phospholipases - antagonists & inhibitors | Lysosomes - metabolism | Inositol 1,4,5-Trisphosphate Receptors - metabolism | Pyrrolidinones - pharmacology | Macrolides - pharmacology | NADP - analogs & derivatives | Female | NADP - metabolism | Heparin - pharmacology | Angiotensin II - metabolism | Arsenicals - pharmacology | Cells, Cultured | Sirolimus - pharmacology | Myometrium - cytology | Animals | Egtazic Acid - pharmacology | Uterus - cytology | Signal Transduction - physiology | Pyridines - pharmacology | Carbolines - pharmacology | Myometrium | Cell receptors | Calcium channels | Genetic aspects | Properties | Angiotensin | T cell receptors | Calcium | ACE inhibitors | Autophagy | Rodents | Index Medicus | Receptors and Signal Transduction
Journal Article
Journal of Pharmacological Sciences, ISSN 1347-8613, 03/2017, Volume 133, Issue 3, pp. 168 - 175
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 04/2018, Volume 62, Issue 4
Gepotidacin (GSK2140944), a novel triazaacenaphthylene bacterial topoisomerase inhibitor, is currently in clinical development for the treatment of bacterial... 
Linezolid | Gepotidacin | THP-1 monocytes | Monocytes | Topoisomerases | Macrolides | Daptomycin | MRSA | Moxifloxacin | Vancomycin | Staphylococcus aureus | STRAINS | monocytes | BROAD-SPECTRUM | ANTIBIOTICS | LINE THP-1 | gepotidacin | SUBCELLULAR-LOCALIZATION | MICROBIOLOGY | topoisomerases | ANTIBACTERIAL AGENTS | CHRONIC RHINOSINUSITIS | THP-1 MACROPHAGES | METHICILLIN-RESISTANT | linezolid | macrolides | daptomycin | vancomycin | PHARMACOLOGY & PHARMACY | moxifloxacin | Oxacillin - pharmacokinetics | Heterocyclic Compounds, 3-Ring - pharmacology | Acenaphthenes - pharmacology | Humans | Methicillin-Resistant Staphylococcus aureus | Microbial Sensitivity Tests | Azithromycin - pharmacokinetics | Macrolides - pharmacokinetics | Vancomycin - pharmacology | Linezolid - pharmacology | Macrolides - pharmacology | Heterocyclic Compounds, 3-Ring - pharmacokinetics | Moxifloxacin - pharmacology | Cell Line | Phagocytes - drug effects | Oxacillin - pharmacology | Moxifloxacin - pharmacokinetics | THP-1 Cells | Azithromycin - pharmacology | Daptomycin - pharmacology | Acenaphthenes - pharmacokinetics | Vancomycin - pharmacokinetics | Anti-Bacterial Agents - pharmacokinetics | Daptomycin - pharmacokinetics | Anti-Bacterial Agents - pharmacology | Linezolid - pharmacokinetics | Staphylococcus aureus - drug effects | Index Medicus
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 01/2007, Volume 51, Issue 1, pp. 231 - 238
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2010, Volume 285, Issue 14, pp. 10959 - 10968
Angiogenin (ANG) is a secreted ribonuclease that cleaves tRNA to initiate a stress-response program in mammalian cells. Here we show that ANG inhibits protein... 
SURVIVAL | EUKARYOTIC TRANSLATION INITIATION | PROCESSING BODIES | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | PRODUCT PATEAMINE-A | ENDOTHELIAL-CELLS | INHIBITS TRANSLATION | CELL-PROLIFERATION | AMYOTROPHIC-LATERAL-SCLEROSIS | EXPRESSION | Arsenites - pharmacology | Protein Biosynthesis | Oxidative Stress | Humans | RNA, Messenger - metabolism | Bone Neoplasms - pathology | Bone Neoplasms - metabolism | Epoxy Compounds - pharmacology | Ribonuclease, Pancreatic - pharmacology | Teratogens - pharmacology | Carrier Proteins - pharmacology | Cytoplasmic Granules - metabolism | Eukaryotic Initiation Factor-2 - metabolism | Macrolides - pharmacology | RNA, Transfer - genetics | Bone Neoplasms - genetics | Phosphorylation - drug effects | Tumor Cells, Cultured | RNA, Transfer - chemistry | Osteosarcoma - metabolism | Eukaryotic Initiation Factor-2 - antagonists & inhibitors | RNA, Transfer - metabolism | RNA, Messenger - genetics | RNA, Small Interfering - pharmacology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Fluorescent Antibody Technique | Thiazoles - pharmacology | Osteosarcoma - genetics | Osteosarcoma - pathology | Index Medicus | Modification | Translation | MicroRNA | RNA | Neurodegeneration | Initiation Factors | Metabolism | Cell Biology | Diseases | Transfer RNA
Journal Article
Naunyn-Schmiedeberg's Archives of Pharmacology, ISSN 0028-1298, 7/2011, Volume 384, Issue 1, pp. 59 - 70
The present study was aimed at investigating the effect and the possible mechanism of idebenone on endogenous glutamate release in nerve terminals of rat... 
Protein kinase A | Neurosciences | Glutamate release | Cerebral cortex | Biomedicine | Idebenone | Ca v 2.2 (N-type) and Ca v 2.1 (P/Q-type) channels | Synaptosomes | Pharmacology/Toxicology | 2.1 (P/Q-type) channels | 2.2 (N-type) and Ca | OXIDATIVE STRESS | CA2+ ENTRY | N-TYPE | Ca(v)2.2 (N-type) and Ca(v)2.1 (P/Q-type) channels | NEUROTRANSMITTER RELEASE | PRESYNAPTIC MODULATION | CORTICAL-NEURONS | PHARMACOLOGY & PHARMACY | TERMINALS SYNAPTOSOMES | INDUCED NEUROTOXICITY | ENERGY-METABOLISM | BRAIN | Synaptosomes - drug effects | Calcium Channels - metabolism | Maleimides - pharmacology | Male | Nerve Endings - metabolism | Synaptosomes - metabolism | omega-Conotoxins | Cerebral Cortex - cytology | Calcium - deficiency | Ubiquinone - pharmacology | Dose-Response Relationship, Drug | Calcium - antagonists & inhibitors | Isoquinolines - pharmacology | Macrolides - pharmacology | Indoles - pharmacology | Sodium-Calcium Exchanger - antagonists & inhibitors | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | 4-Aminopyridine - pharmacology | Cyclic AMP-Dependent Protein Kinases - metabolism | Membrane Potentials - drug effects | Calcium - pharmacology | Clonazepam - analogs & derivatives | Ubiquinone - analogs & derivatives | Enzyme Inhibitors - pharmacology | Clonazepam - pharmacology | Rats | Protein Kinase C - antagonists & inhibitors | Thiazepines - pharmacology | Dantrolene - pharmacology | Calcium Channel Blockers - pharmacology | Potassium - pharmacology | Sulfonamides - pharmacology | Rats, Sprague-Dawley | Glutamate Plasma Membrane Transport Proteins - antagonists & inhibitors | Pyrroles - pharmacology | Animals | Calcium Signaling - drug effects | Nerve Endings - drug effects | Glutamic Acid - metabolism | Protein Kinase Inhibitors - pharmacology | Carbazoles - pharmacology | Aspartic Acid - pharmacology | Brain | Amino acids | Glutamate | Protein kinases | Nerve endings | Calcium (intracellular) | Calcium channels (N-type) | Calcium channels (voltage-gated) | Cortex | Potassium channels | Calcium influx | Calcium channels (Q-type) | Glutamic acid transporter | Membrane potential | vesicular transporters | Calcium (extracellular) | Na super(+)/Ca super(2+)-exchanging ATPase | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2009, Volume 119, Issue 5, pp. 1109 - 1123
Imatinib mesylate (IM), a potent inhibitor of the BCR/ABL tyrosine kinase, has become standard first-line therapy for patients with chronic myeloid leukemia... 
CHRONIC MYELOGENOUS LEUKEMIA | MEDICINE, RESEARCH & EXPERIMENTAL | MALIGNANT GLIOMA-CELLS | BLAST CRISIS | CLINICAL RESISTANCE | BCR-ABL MUTATIONS | ENDOPLASMIC-RETICULUM | CYTOCHROME-C RELEASE | CASPASE ACTIVATION | IMATINIB RESISTANCE | CHRONIC MYELOID-LEUKEMIA | Transcription Factor CHOP - genetics | Neoplastic Stem Cells - cytology | Gene Expression - drug effects | Calcium - metabolism | Gene Expression - genetics | Microtubule-Associated Proteins - metabolism | Neoplastic Stem Cells - drug effects | Humans | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy | Endoplasmic Reticulum - metabolism | Antineoplastic Agents - therapeutic use | Autophagy - physiology | Thiazoles - therapeutic use | Autophagy - drug effects | Chloroquine - pharmacology | Neoplastic Stem Cells - metabolism | RNA Interference | Endoplasmic Reticulum - drug effects | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology | Macrolides - pharmacology | Antineoplastic Agents - pharmacology | Cell Death - drug effects | Dasatinib | Chloroquine - therapeutic use | Piperazines - therapeutic use | Pyrimidines - pharmacology | Imatinib Mesylate | Piperazines - pharmacology | Mice, Inbred C3H | Xenograft Model Antitumor Assays | Fusion Proteins, bcr-abl - genetics | Animals | Cell Death - physiology | Protein Kinase Inhibitors - therapeutic use | Pyrimidines - therapeutic use | Fusion Proteins, bcr-abl - antagonists & inhibitors | Cell Line, Tumor | Leukemia, Myelogenous, Chronic, BCR-ABL Positive - metabolism | Mice | Protein Kinase Inhibitors - pharmacology | Thiazoles - pharmacology | Benzamides | Macrolides - therapeutic use | Protein-Tyrosine Kinases - antagonists & inhibitors | Causes of | Physiological aspects | Genetic aspects | Chronic myeloid leukemia | Research | Drug therapy | Phagocytosis | Index Medicus | Abridged Index Medicus
Journal Article
Parasitology Research, ISSN 0932-0113, 6/2018, Volume 117, Issue 6, pp. 1941 - 1952
Many countries in Latin America have recently experienced outbreaks of Zika and chikungunya fever, in additional to the usual burden imposed by dengue, all of... 
Medical Microbiology | Biomedicine | Immunology | Microbiology | Aedes spp | Oviposition | Insecticide toxicity | Larvicide | Field trails | RESISTANCE MECHANISMS | AEDES-AEGYPTI DIPTERA | FRENCH-WEST-INDIES | CULEX-QUINQUEFASCIATUS | LAMBDA-CYHALOTHRIN | MOSQUITO LARVAE | 1ST REPORT | STEGOMYIA-AEGYPTI | NATURALLY DERIVED INSECTICIDE | LATIN-AMERICAN COUNTRIES | PARASITOLOGY | ortho-Aminobenzoates - pharmacology | Nitriles - pharmacology | Chikungunya Fever - prevention & control | Pyrethrins - pharmacology | Insect Vectors - virology | Temefos - pharmacology | Zika Virus Infection - virology | Aedes - virology | Cemeteries | Insect Vectors - drug effects | Larva - drug effects | Macrolides - pharmacology | Nitro Compounds - pharmacology | Pupa - growth & development | Zika Virus Infection - prevention & control | Oxazines - pharmacology | Insecticides - pharmacology | Neonicotinoids - pharmacology | Aedes - drug effects | Dengue - virology | Chikungunya Fever - virology | Dengue - prevention & control | Chikungunya Fever - transmission | Zika Virus Infection - transmission | Animals | Dengue - transmission | Mexico | Pyridines - pharmacology | Thiazoles - pharmacology | Drug Combinations | Spiro Compounds - pharmacology | Equipment and supplies | Health aspects | Pesticides | Infection control | Spinosad | Toxicity | Dengue | Pyriproxyfen | Insecticides | Outbreaks | Vectors | Fever | Eggs | Larvicides | Disease transmission | Thiamethoxam | Imidacloprid | Cyhalothrin | Index Medicus
Journal Article
Science, ISSN 0036-8075, 1/2006, Volume 311, Issue 5759, pp. 374 - 377
Journal Article