American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 10/2009, Volume 180, Issue 7, pp. 640 - 648
Rationale. Sustained sepsis-associated immunosuppression is associated with uncontrolled infection, multiple organ dysfunction, and death. Objectives: In the...
Shock | Sepsis | Immunoparalysis | HLA-DR | Immune system | UNITED-STATES | DIAGNOSTIC-VALUE | shock | INNATE IMMUNE-RESPONSE | LEUKOCYTE ANTIGEN-DR | SEVERE TRAUMA | CLASS-II EXPRESSION | SYSTEMIC INFLAMMATION | SEPTIC SHOCK PATIENTS | RESPIRATORY SYSTEM | ENDOTOXIN TOLERANCE | immune system | immunoparalysis | CRITICALLY-ILL PATIENTS | sepsis | CRITICAL CARE MEDICINE | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | HLA-DR Antigens - blood | Male | Sepsis - complications | Shock, Septic - immunology | Granulocyte-Macrophage Colony-Stimulating Factor - therapeutic use | Flow Cytometry | Immune Tolerance - immunology | Shock, Septic - blood | Female | Granulocyte-Macrophage Colony-Stimulating Factor - blood | Length of Stay - statistics & numerical data | Immune Tolerance - drug effects | Severity of Illness Index | Sepsis - immunology | Double-Blind Method | Shock, Septic - complications | Treatment Outcome | Biomarkers - blood | Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Respiration, Artificial - statistics & numerical data | HLA-DR Antigens - immunology | Sepsis - blood | HLA-DR Antigens - drug effects
Shock | Sepsis | Immunoparalysis | HLA-DR | Immune system | UNITED-STATES | DIAGNOSTIC-VALUE | shock | INNATE IMMUNE-RESPONSE | LEUKOCYTE ANTIGEN-DR | SEVERE TRAUMA | CLASS-II EXPRESSION | SYSTEMIC INFLAMMATION | SEPTIC SHOCK PATIENTS | RESPIRATORY SYSTEM | ENDOTOXIN TOLERANCE | immune system | immunoparalysis | CRITICALLY-ILL PATIENTS | sepsis | CRITICAL CARE MEDICINE | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | HLA-DR Antigens - blood | Male | Sepsis - complications | Shock, Septic - immunology | Granulocyte-Macrophage Colony-Stimulating Factor - therapeutic use | Flow Cytometry | Immune Tolerance - immunology | Shock, Septic - blood | Female | Granulocyte-Macrophage Colony-Stimulating Factor - blood | Length of Stay - statistics & numerical data | Immune Tolerance - drug effects | Severity of Illness Index | Sepsis - immunology | Double-Blind Method | Shock, Septic - complications | Treatment Outcome | Biomarkers - blood | Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Respiration, Artificial - statistics & numerical data | HLA-DR Antigens - immunology | Sepsis - blood | HLA-DR Antigens - drug effects
Journal Article
Brain, Behavior, and Immunity, ISSN 0889-1591, 2015, Volume 52, pp. 81 - 87
Highlights • Of 23 cytokines, only G-CSF increased in mice after controlled cortical impact. • Serum G-CSF levels correlated with the levels of several brain...
Psychiatry | Allergy and Immunology | Neuroinflammation | Biomarker | Traumatic brain injury | G-CSF | Blood–brain barrier | Blood-brain barrier | SEVERITY SCORE | CYTOKINES | PSYCHIATRY | INTERLEUKIN-1-BETA | BARRIER | MODEL | IMMUNOLOGY | Blood brain barrier | NEUROSCIENCES | IMMUNE | INTRACEREBROVENTRICULAR INJECTION | Age Factors | Humans | Mice, Inbred C57BL | Middle Aged | Granulocyte Colony-Stimulating Factor - blood | Male | Biomarkers - blood | Blood-Brain Barrier - metabolism | Brain - metabolism | Young Adult | Pilot Projects | Animals | Aged, 80 and over | Adult | Female | Aged | Mice | Brain Injuries, Traumatic - blood | Cytokines - blood | Disease Models, Animal | Brain | Macrophage colony stimulating factor | Granulocyte colony-stimulating factor | Injuries | Analysis
Psychiatry | Allergy and Immunology | Neuroinflammation | Biomarker | Traumatic brain injury | G-CSF | Blood–brain barrier | Blood-brain barrier | SEVERITY SCORE | CYTOKINES | PSYCHIATRY | INTERLEUKIN-1-BETA | BARRIER | MODEL | IMMUNOLOGY | Blood brain barrier | NEUROSCIENCES | IMMUNE | INTRACEREBROVENTRICULAR INJECTION | Age Factors | Humans | Mice, Inbred C57BL | Middle Aged | Granulocyte Colony-Stimulating Factor - blood | Male | Biomarkers - blood | Blood-Brain Barrier - metabolism | Brain - metabolism | Young Adult | Pilot Projects | Animals | Aged, 80 and over | Adult | Female | Aged | Mice | Brain Injuries, Traumatic - blood | Cytokines - blood | Disease Models, Animal | Brain | Macrophage colony stimulating factor | Granulocyte colony-stimulating factor | Injuries | Analysis
Journal Article
Nature Communications, ISSN 2041-1723, 04/2015, Volume 6, Issue 1, p. 6994
Aortic dissection and intramural haematoma comprise an aortopathy involving separation of the aortic wall. Underlying mechanisms of the condition remain...
ATHEROSCLEROTIC LESIONS | ACTIVATED MOUSE MACROPHAGES | DISSECTION | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | ANEURYSMS | GROWTH | ANGIOTENSIN-II | ENDOCYTOSIS | CONTRIBUTES | PROGRESSION | Proto-Oncogene Proteins - metabolism | Up-Regulation | Kruppel-Like Factor 6 | Humans | Mice, Inbred C57BL | Middle Aged | Hematoma - etiology | Male | Proto-Oncogene Proteins - genetics | Aortic Aneurysm - etiology | Case-Control Studies | Mice, Knockout | Animals | Aortic Aneurysm - blood | Kruppel-Like Transcription Factors - metabolism | Aged, 80 and over | Adult | Female | Aged | Aneurysm, Dissecting - blood | Kruppel-Like Transcription Factors - genetics | Aneurysm, Dissecting - etiology | Granulocyte-Macrophage Colony-Stimulating Factor - blood | Hematoma - blood
ATHEROSCLEROTIC LESIONS | ACTIVATED MOUSE MACROPHAGES | DISSECTION | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | ANEURYSMS | GROWTH | ANGIOTENSIN-II | ENDOCYTOSIS | CONTRIBUTES | PROGRESSION | Proto-Oncogene Proteins - metabolism | Up-Regulation | Kruppel-Like Factor 6 | Humans | Mice, Inbred C57BL | Middle Aged | Hematoma - etiology | Male | Proto-Oncogene Proteins - genetics | Aortic Aneurysm - etiology | Case-Control Studies | Mice, Knockout | Animals | Aortic Aneurysm - blood | Kruppel-Like Transcription Factors - metabolism | Aged, 80 and over | Adult | Female | Aged | Aneurysm, Dissecting - blood | Kruppel-Like Transcription Factors - genetics | Aneurysm, Dissecting - etiology | Granulocyte-Macrophage Colony-Stimulating Factor - blood | Hematoma - blood
Journal Article
Critical Care Medicine, ISSN 0090-3493, 01/2012, Volume 40, Issue 1, pp. 90 - 97
Rationale: Despite recent advances in critical care and ventilator management, acute lung injury and acute respiratory distress syndrome continue to cause...
Acute respiratory distress syndrome | Innate immunity | Sepsis | Growth factors | CELLS | growth factors | ACUTE RESPIRATORY-DISTRESS | CLINICAL-TRIAL | innate immunity | GM-CSF | acute respiratory distress syndrome | QUALITY-OF-LIFE | OUTCOMES | SURVIVORS | sepsis | SEVERE SEPSIS | CRITICAL CARE MEDICINE | Recombinant Proteins - therapeutic use | Granulocyte-Macrophage Colony-Stimulating Factor - administration & dosage | Double-Blind Method | Granulocyte-Macrophage Colony-Stimulating Factor - analysis | Humans | Middle Aged | Tumor Necrosis Factor-alpha - blood | Male | Treatment Outcome | Granulocyte-Macrophage Colony-Stimulating Factor - therapeutic use | Respiration, Artificial | Interleukin-6 - blood | Female | Acute Lung Injury - drug therapy | Bronchoalveolar Lavage Fluid - chemistry | Infusions, Intravenous | Interleukin-8 - blood | Granulocyte-Macrophage Colony-Stimulating Factor - blood
Acute respiratory distress syndrome | Innate immunity | Sepsis | Growth factors | CELLS | growth factors | ACUTE RESPIRATORY-DISTRESS | CLINICAL-TRIAL | innate immunity | GM-CSF | acute respiratory distress syndrome | QUALITY-OF-LIFE | OUTCOMES | SURVIVORS | sepsis | SEVERE SEPSIS | CRITICAL CARE MEDICINE | Recombinant Proteins - therapeutic use | Granulocyte-Macrophage Colony-Stimulating Factor - administration & dosage | Double-Blind Method | Granulocyte-Macrophage Colony-Stimulating Factor - analysis | Humans | Middle Aged | Tumor Necrosis Factor-alpha - blood | Male | Treatment Outcome | Granulocyte-Macrophage Colony-Stimulating Factor - therapeutic use | Respiration, Artificial | Interleukin-6 - blood | Female | Acute Lung Injury - drug therapy | Bronchoalveolar Lavage Fluid - chemistry | Infusions, Intravenous | Interleukin-8 - blood | Granulocyte-Macrophage Colony-Stimulating Factor - blood
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 06/2010, Volume 181, Issue 12, pp. 1345 - 1354
Rationale: Inhaled granulocyte/macrophage-colony stimulating factor (GM-CSF) is a promising therapy for pulmonary alveolar proteinosis (PAP) but has not been...
AUTOANTIBODIES | IMMUNITY | DEFICIENT MICE | RESPIRATORY SYSTEM | WHOLE LUNG LAVAGE | CRITICAL CARE MEDICINE | Enzyme-Linked Immunosorbent Assay - methods | Pulmonary Alveolar Proteinosis - drug therapy | Granulocyte-Macrophage Colony-Stimulating Factor - administration & dosage | Prospective Studies | Humans | Japan | Middle Aged | Pulmonary Alveolar Proteinosis - diagnostic imaging | Administration, Inhalation | Tomography, X-Ray Computed - methods | Male | Treatment Outcome | Lung - diagnostic imaging | Pulmonary Alveolar Proteinosis - blood | Biomarkers - blood | Recombinant Proteins | Granulocyte-Macrophage Colony-Stimulating Factor - therapeutic use | Dose-Response Relationship, Drug | Adult | Female | Granulocyte-Macrophage Colony-Stimulating Factor - blood | Cohort Studies | C. Critical Care
AUTOANTIBODIES | IMMUNITY | DEFICIENT MICE | RESPIRATORY SYSTEM | WHOLE LUNG LAVAGE | CRITICAL CARE MEDICINE | Enzyme-Linked Immunosorbent Assay - methods | Pulmonary Alveolar Proteinosis - drug therapy | Granulocyte-Macrophage Colony-Stimulating Factor - administration & dosage | Prospective Studies | Humans | Japan | Middle Aged | Pulmonary Alveolar Proteinosis - diagnostic imaging | Administration, Inhalation | Tomography, X-Ray Computed - methods | Male | Treatment Outcome | Lung - diagnostic imaging | Pulmonary Alveolar Proteinosis - blood | Biomarkers - blood | Recombinant Proteins | Granulocyte-Macrophage Colony-Stimulating Factor - therapeutic use | Dose-Response Relationship, Drug | Adult | Female | Granulocyte-Macrophage Colony-Stimulating Factor - blood | Cohort Studies | C. Critical Care
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 10/2017, Volume 23, Issue 19, pp. 5703 - 5710
Purpose: Binding of colony-stimulating factor 1 (CSF1) ligand to the CSF1 receptor (CSF1R) regulates survival of tumor-associated macrophages, which generally...
METASTASIS | INHIBITION | ONCOLOGY | IMMUNOTHERAPY | MACROPHAGES | BLOCKADE | CSF-1 | ADOPTIVE CELL TRANSFER | CANCER | EXPRESSION | PROGRESSION | Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - antagonists & inhibitors | Interleukin-1 - blood | Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - blood | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Male | Treatment Outcome | Drug-Related Side Effects and Adverse Reactions - pathology | Neoplasms - drug therapy | Antibodies, Monoclonal - blood | Dose-Response Relationship, Drug | Maximum Tolerated Dose | Macrophage Colony-Stimulating Factor - blood | Neoplasms - genetics | Antibodies, Monoclonal - administration & dosage | Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Aged, 80 and over | Female | Aged | Macrophage Colony-Stimulating Factor - genetics | Neoplasms - pathology | Alkaline phosphatase | Intravenous administration | Toxicity | Macrophages | Anticancer properties | Quality | Safety engineering | Colony-stimulating factor | Binding | Edema | Deafness | Pharmacodynamics | Cell survival | Colonies | Macrophage colony-stimulating factor | Fatigue | Nausea | Pharmacology | Disease control | Patients | Immunosuppression | Experimental design | Antitumor activity | Ligands | Aspartate aminotransferase | Receptor mechanisms | Solid tumors | Pharmacokinetics | Tumors | Cancer
METASTASIS | INHIBITION | ONCOLOGY | IMMUNOTHERAPY | MACROPHAGES | BLOCKADE | CSF-1 | ADOPTIVE CELL TRANSFER | CANCER | EXPRESSION | PROGRESSION | Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - antagonists & inhibitors | Interleukin-1 - blood | Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - blood | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Male | Treatment Outcome | Drug-Related Side Effects and Adverse Reactions - pathology | Neoplasms - drug therapy | Antibodies, Monoclonal - blood | Dose-Response Relationship, Drug | Maximum Tolerated Dose | Macrophage Colony-Stimulating Factor - blood | Neoplasms - genetics | Antibodies, Monoclonal - administration & dosage | Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Aged, 80 and over | Female | Aged | Macrophage Colony-Stimulating Factor - genetics | Neoplasms - pathology | Alkaline phosphatase | Intravenous administration | Toxicity | Macrophages | Anticancer properties | Quality | Safety engineering | Colony-stimulating factor | Binding | Edema | Deafness | Pharmacodynamics | Cell survival | Colonies | Macrophage colony-stimulating factor | Fatigue | Nausea | Pharmacology | Disease control | Patients | Immunosuppression | Experimental design | Antitumor activity | Ligands | Aspartate aminotransferase | Receptor mechanisms | Solid tumors | Pharmacokinetics | Tumors | Cancer
Journal Article
Journal of the American Society of Nephrology, ISSN 1046-6673, 02/2015, Volume 26, Issue 2, pp. 379 - 389
A noninvasive means to predict the onset and recurrence of lupus nephritis (LN) before overt renal injury is needed to optimize and individualize treatment....
REPAIR | TUBULOINTERSTITIAL LESIONS | PREDICTORS | MACROPHAGE | DISEASE | UROLOGY & NEPHROLOGY | PROLIFERATION | GELATINASE-ASSOCIATED LIPOCALIN | CSF-1 | ASSOCIATION | ERYTHEMATOSUS | Predictive Value of Tests | Biomarkers - urine | Humans | Middle Aged | Kidney Glomerulus - physiopathology | Male | Case-Control Studies | Macrophage Colony-Stimulating Factor - urine | Lupus Nephritis - blood | Young Adult | Adult | Female | Retrospective Studies | Kidney Tubules - pathology | Kidney Tubules - metabolism | Severity of Illness Index | Reproducibility of Results | Biomarkers - blood | Disease Progression | Macrophage Colony-Stimulating Factor - blood | Biopsy | Adolescent | Lupus Nephritis - urine | Aged | Longitudinal Studies | Lupus Nephritis - diagnosis | macrophages | rheumatology | kidney disease | lupus nephritis | glomerulonephritis | renal tubular epithelial cells | Basic Research
REPAIR | TUBULOINTERSTITIAL LESIONS | PREDICTORS | MACROPHAGE | DISEASE | UROLOGY & NEPHROLOGY | PROLIFERATION | GELATINASE-ASSOCIATED LIPOCALIN | CSF-1 | ASSOCIATION | ERYTHEMATOSUS | Predictive Value of Tests | Biomarkers - urine | Humans | Middle Aged | Kidney Glomerulus - physiopathology | Male | Case-Control Studies | Macrophage Colony-Stimulating Factor - urine | Lupus Nephritis - blood | Young Adult | Adult | Female | Retrospective Studies | Kidney Tubules - pathology | Kidney Tubules - metabolism | Severity of Illness Index | Reproducibility of Results | Biomarkers - blood | Disease Progression | Macrophage Colony-Stimulating Factor - blood | Biopsy | Adolescent | Lupus Nephritis - urine | Aged | Longitudinal Studies | Lupus Nephritis - diagnosis | macrophages | rheumatology | kidney disease | lupus nephritis | glomerulonephritis | renal tubular epithelial cells | Basic Research
Journal Article
British Journal of Haematology, ISSN 0007-1048, 07/2013, Volume 162, Issue 1, pp. 107 - 111
Summary Peripheral blood haematopoietic progenitor cell mobilization has become a standard procedure prior to autologous stem cell transplantation. Biosimilar...
granulocyte colony‐stimulating factor | engraftment | stem cell harvest | mobilization | biosimilar | Engraftment | Mobilization | Granulocyte colony-stimulating factor | Biosimilar | Stem cell harvest | ANTIBODIES | EXPERIENCE | granulocyte colony-stimulating factor | HEMATOLOGY | TRANSPLANTATION | Hematopoietic Stem Cells - drug effects | Antigens, CD34 - metabolism | Hematopoietic Stem Cell Mobilization - methods | Humans | Middle Aged | Male | Transplantation, Autologous | Hematopoietic Stem Cells - metabolism | Biosimilar Pharmaceuticals - pharmacology | Young Adult | Granulocyte Colony-Stimulating Factor - pharmacology | European Union | Hematopoietic Stem Cells - cytology | Adolescent | Adult | Female | Aged | Retrospective Studies | Graft Survival - drug effects | Peripheral Blood Stem Cell Transplantation | Usage | Macrophage colony stimulating factor | Analysis | Hematopoietic stem cells
granulocyte colony‐stimulating factor | engraftment | stem cell harvest | mobilization | biosimilar | Engraftment | Mobilization | Granulocyte colony-stimulating factor | Biosimilar | Stem cell harvest | ANTIBODIES | EXPERIENCE | granulocyte colony-stimulating factor | HEMATOLOGY | TRANSPLANTATION | Hematopoietic Stem Cells - drug effects | Antigens, CD34 - metabolism | Hematopoietic Stem Cell Mobilization - methods | Humans | Middle Aged | Male | Transplantation, Autologous | Hematopoietic Stem Cells - metabolism | Biosimilar Pharmaceuticals - pharmacology | Young Adult | Granulocyte Colony-Stimulating Factor - pharmacology | European Union | Hematopoietic Stem Cells - cytology | Adolescent | Adult | Female | Aged | Retrospective Studies | Graft Survival - drug effects | Peripheral Blood Stem Cell Transplantation | Usage | Macrophage colony stimulating factor | Analysis | Hematopoietic stem cells
Journal Article
Hepatology, ISSN 0270-9139, 12/2014, Volume 60, Issue 6, pp. 1879 - 1890
Chronic hepatitis C virus (HCV) infection is characterized by progressive hepatic fibrosis, a process dependent on monocyte recruitment and accumulation into...
UNITED-STATES | VIRAL INTERACTIONS | MORTALITY | B-VIRUS | HEPATOCELLULAR-CARCINOMA | COINFECTED PATIENTS | CHRONIC LIVER-DISEASE | RISK | PREVALENCE | GASTROENTEROLOGY & HEPATOLOGY | DUAL INFECTION | Killer Cells, Natural - secretion | Cell Line | Hepatitis C, Chronic - metabolism | Liver Cirrhosis - immunology | Interleukins - blood | Humans | Interferon-gamma - secretion | Middle Aged | Hepatic Stellate Cells - metabolism | Male | Hepatitis C, Chronic - complications | Hepatocytes - metabolism | Interleukin-13 - metabolism | Case-Control Studies | Collagen Type I - biosynthesis | Macrophage Colony-Stimulating Factor - blood | Liver Cirrhosis - metabolism | Adult | Female | Aged | Matrix Metalloproteinase 1 - metabolism | Hepatitis | Liver cirrhosis | Collagen | Chemokines
UNITED-STATES | VIRAL INTERACTIONS | MORTALITY | B-VIRUS | HEPATOCELLULAR-CARCINOMA | COINFECTED PATIENTS | CHRONIC LIVER-DISEASE | RISK | PREVALENCE | GASTROENTEROLOGY & HEPATOLOGY | DUAL INFECTION | Killer Cells, Natural - secretion | Cell Line | Hepatitis C, Chronic - metabolism | Liver Cirrhosis - immunology | Interleukins - blood | Humans | Interferon-gamma - secretion | Middle Aged | Hepatic Stellate Cells - metabolism | Male | Hepatitis C, Chronic - complications | Hepatocytes - metabolism | Interleukin-13 - metabolism | Case-Control Studies | Collagen Type I - biosynthesis | Macrophage Colony-Stimulating Factor - blood | Liver Cirrhosis - metabolism | Adult | Female | Aged | Matrix Metalloproteinase 1 - metabolism | Hepatitis | Liver cirrhosis | Collagen | Chemokines
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 12/2009, Volume 27, Issue 35, pp. 5911 - 5918
Purpose Granulocyte-macrophage colony-stimulating factor (GM-CSF)-secreting tumor vaccines have demonstrated bioactivity but may be limited by disease burdens...
AUTOLOGOUS MELANOMA-CELLS | METASTATIC MELANOMA | LUNG-CANCER | ONCOLOGY | PROSTATE-CANCER | PANCREATIC-CANCER | REGULATORY T-CELLS | PERIPHERAL-BLOOD | CELLULAR IMMUNOTHERAPY | ANTITUMOR IMMUNITY | GENE-TRANSFER | Breast Neoplasms - secondary | Cyclophosphamide - administration & dosage | Breast Neoplasms - immunology | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Breast Neoplasms - therapy | CD4-Positive T-Lymphocytes - immunology | Cancer Vaccines - genetics | Dose-Response Relationship, Drug | Transfection | Granulocyte-Macrophage Colony-Stimulating Factor - biosynthesis | Time Factors | Adult | Female | Immunization Schedule | Receptor, ErbB-2 - immunology | Granulocyte-Macrophage Colony-Stimulating Factor - blood | Doxorubicin - administration & dosage | Cell Line | Drug Administration Schedule | Immunotherapy, Adoptive | Cancer Vaccines - administration & dosage | Cancer Vaccines - adverse effects | Treatment Outcome | Combined Modality Therapy | Breast Neoplasms - drug therapy | Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged | Index Medicus | Original Reports | Bc8 | To6
AUTOLOGOUS MELANOMA-CELLS | METASTATIC MELANOMA | LUNG-CANCER | ONCOLOGY | PROSTATE-CANCER | PANCREATIC-CANCER | REGULATORY T-CELLS | PERIPHERAL-BLOOD | CELLULAR IMMUNOTHERAPY | ANTITUMOR IMMUNITY | GENE-TRANSFER | Breast Neoplasms - secondary | Cyclophosphamide - administration & dosage | Breast Neoplasms - immunology | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Breast Neoplasms - therapy | CD4-Positive T-Lymphocytes - immunology | Cancer Vaccines - genetics | Dose-Response Relationship, Drug | Transfection | Granulocyte-Macrophage Colony-Stimulating Factor - biosynthesis | Time Factors | Adult | Female | Immunization Schedule | Receptor, ErbB-2 - immunology | Granulocyte-Macrophage Colony-Stimulating Factor - blood | Doxorubicin - administration & dosage | Cell Line | Drug Administration Schedule | Immunotherapy, Adoptive | Cancer Vaccines - administration & dosage | Cancer Vaccines - adverse effects | Treatment Outcome | Combined Modality Therapy | Breast Neoplasms - drug therapy | Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged | Index Medicus | Original Reports | Bc8 | To6
Journal Article
World Journal of Gastroenterology, ISSN 1007-9327, 02/2018, Volume 24, Issue 5, pp. 623 - 630
AIM to examine the relationship between elevated granulocyte-macrophage colony-stimulating factor (GMCSF) auto-antibodies (Ab) level and time to surgical...
Inflammatory bowel disease | Granulocytemacrophage colony-stimulating factor antibody | Crohn's disease | Surgery | FACTOR AUTOANTIBODIES | INFLAMMATORY-BOWEL-DISEASE | FACTOR GM-CSF | COHORT | Granulocyte-macrophage colony-stimulating factor antibody | SARGRAMOSTIM | GASTROENTEROLOGY & HEPATOLOGY | Crohn Disease - genetics | Recurrence | Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Ileal Diseases - surgery | Autoantibodies - blood | Humans | Middle Aged | Crohn Disease - surgery | Male | Ileum - immunology | Time Factors | Adult | Female | Ileal Diseases - genetics | Retrospective Studies | Ileal Diseases - immunology | Autophagy-Related Proteins - genetics | Granulocyte-Macrophage Colony-Stimulating Factor - blood | Risk Assessment | Biomarkers - analysis | Crohn Disease - immunology | Ileal Diseases - blood | Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Crohn Disease - blood | Ileum - surgery
Inflammatory bowel disease | Granulocytemacrophage colony-stimulating factor antibody | Crohn's disease | Surgery | FACTOR AUTOANTIBODIES | INFLAMMATORY-BOWEL-DISEASE | FACTOR GM-CSF | COHORT | Granulocyte-macrophage colony-stimulating factor antibody | SARGRAMOSTIM | GASTROENTEROLOGY & HEPATOLOGY | Crohn Disease - genetics | Recurrence | Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Ileal Diseases - surgery | Autoantibodies - blood | Humans | Middle Aged | Crohn Disease - surgery | Male | Ileum - immunology | Time Factors | Adult | Female | Ileal Diseases - genetics | Retrospective Studies | Ileal Diseases - immunology | Autophagy-Related Proteins - genetics | Granulocyte-Macrophage Colony-Stimulating Factor - blood | Risk Assessment | Biomarkers - analysis | Crohn Disease - immunology | Ileal Diseases - blood | Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Crohn Disease - blood | Ileum - surgery
Journal Article
Biology of Blood and Marrow Transplantation, ISSN 1083-8791, 2012, Volume 18, Issue 7, pp. 1128 - 1135
Peripheral blood progenitor cell mobilization with intermediate-dose cyclophosphamide (ID-CY) and granulocyte colony-stimulating factor (G-CSF) has been shown...
Hematology, Oncology and Palliative Medicine | High dose therapy | Lenalidomide | Autologous transplantation | Chemomobilization | PROGENITOR CELLS | COLLECTION | LENALIDOMIDE THERAPY | OVERCOMES | IMMUNOLOGY | G-CSF | CHEMOTHERAPY | TRANSPLANTATION | AGENTS | HEMATOLOGY | Neutrophils - cytology | Cyclophosphamide - administration & dosage | Blood Platelets - immunology | Drug Administration Schedule | Hematopoietic Stem Cell Mobilization - methods | Humans | Middle Aged | Neutrophils - immunology | Hematopoietic Stem Cell Transplantation | Male | Multiple Myeloma - immunology | Transplantation, Autologous | Thalidomide - administration & dosage | Remission Induction | Thalidomide - analogs & derivatives | Drug Dosage Calculations | Multiple Myeloma - therapy | Antigens, CD34 - immunology | Blood Platelets - cytology | Treatment Failure | Adult | Female | Aged | Granulocyte Colony-Stimulating Factor - administration & dosage | Care and treatment | Cyclophosphamide | Chemotherapy | Granulocyte colony-stimulating factor | Multiple myeloma | Stem cells | Dosage and administration | Transplantation | Macrophage colony stimulating factor | Hematopoietic stem cells | Cancer | Index Medicus
Hematology, Oncology and Palliative Medicine | High dose therapy | Lenalidomide | Autologous transplantation | Chemomobilization | PROGENITOR CELLS | COLLECTION | LENALIDOMIDE THERAPY | OVERCOMES | IMMUNOLOGY | G-CSF | CHEMOTHERAPY | TRANSPLANTATION | AGENTS | HEMATOLOGY | Neutrophils - cytology | Cyclophosphamide - administration & dosage | Blood Platelets - immunology | Drug Administration Schedule | Hematopoietic Stem Cell Mobilization - methods | Humans | Middle Aged | Neutrophils - immunology | Hematopoietic Stem Cell Transplantation | Male | Multiple Myeloma - immunology | Transplantation, Autologous | Thalidomide - administration & dosage | Remission Induction | Thalidomide - analogs & derivatives | Drug Dosage Calculations | Multiple Myeloma - therapy | Antigens, CD34 - immunology | Blood Platelets - cytology | Treatment Failure | Adult | Female | Aged | Granulocyte Colony-Stimulating Factor - administration & dosage | Care and treatment | Cyclophosphamide | Chemotherapy | Granulocyte colony-stimulating factor | Multiple myeloma | Stem cells | Dosage and administration | Transplantation | Macrophage colony stimulating factor | Hematopoietic stem cells | Cancer | Index Medicus
Journal Article
Cancer Cell, ISSN 1535-6108, 05/2014, Volume 25, Issue 5, pp. 605 - 620
The close vicinity of cancer cells undergoing epithelial-mesenchymal transition (EMT) and tumor-associated macrophages (TAMs) at the invasive front of tumors...
MYELOID SUPPRESSOR-CELLS | PARACRINE LOOP | INVASION | COLONY-STIMULATING FACTOR | ONCOLOGY | GM-CSF | MELANOMA VACCINE | TUMOR-ASSOCIATED MACROPHAGES | NF-KAPPA-B | ESTROGEN-RECEPTOR | T-CELLS | CELL BIOLOGY | Neoplasm Transplantation | Chemokines, CC - blood | Macrophages - pathology | Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Humans | Mesoderm - cytology | Mice, SCID | Breast Neoplasms - metabolism | Chemokines, CC - antagonists & inhibitors | Feedback, Physiological | Neoplasm Metastasis | Animals | MCF-7 Cells | Breast Neoplasms - pathology | Epithelial-Mesenchymal Transition | Cell Line, Tumor | Breast Neoplasms - mortality | Female | Granulocyte-Macrophage Colony-Stimulating Factor - antagonists & inhibitors | Mice, Inbred NOD | Mice | Granulocyte-Macrophage Colony-Stimulating Factor - blood | Macrophages - immunology | Chemokines, CC - metabolism | Breast cancer | Metastasis | Macrophages | Cancer cells | Stem cells
MYELOID SUPPRESSOR-CELLS | PARACRINE LOOP | INVASION | COLONY-STIMULATING FACTOR | ONCOLOGY | GM-CSF | MELANOMA VACCINE | TUMOR-ASSOCIATED MACROPHAGES | NF-KAPPA-B | ESTROGEN-RECEPTOR | T-CELLS | CELL BIOLOGY | Neoplasm Transplantation | Chemokines, CC - blood | Macrophages - pathology | Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Humans | Mesoderm - cytology | Mice, SCID | Breast Neoplasms - metabolism | Chemokines, CC - antagonists & inhibitors | Feedback, Physiological | Neoplasm Metastasis | Animals | MCF-7 Cells | Breast Neoplasms - pathology | Epithelial-Mesenchymal Transition | Cell Line, Tumor | Breast Neoplasms - mortality | Female | Granulocyte-Macrophage Colony-Stimulating Factor - antagonists & inhibitors | Mice, Inbred NOD | Mice | Granulocyte-Macrophage Colony-Stimulating Factor - blood | Macrophages - immunology | Chemokines, CC - metabolism | Breast cancer | Metastasis | Macrophages | Cancer cells | Stem cells
Journal Article
Cytokine, ISSN 1043-4666, 05/2013, Volume 62, Issue 2, pp. 278 - 285
This study aimed to determine the role of granulocyte colony-stimulating factor (G-CSF), induced by a promising radiation countermeasure, gamma tocotrienol...
Hematopoietic tissue | Gamma tocotrienol | Mice | Gamma radiation | Radioprotection | TOTAL-BODY IRRADIATION | PROGENITOR CELLS | MULTILINEAGE HEMATOPOIETIC RECOVERY | BIOCHEMISTRY & MOLECULAR BIOLOGY | PERIPHERAL-BLOOD | IMMUNOLOGY | INDUCED MYELOSUPPRESSION | CELL BIOLOGY | NONHUMAN PRIMATE MODEL | FACTOR G-CSF | RECEPTOR AGONIST | SUPEROXIDE-DISMUTASE | TOCOPHEROL SUCCINATE | Antibodies, Neutralizing | Granulocyte Colony-Stimulating Factor - blood | Vitamin E - analogs & derivatives | Male | Whole-Body Irradiation - adverse effects | Animals | Chromans - pharmacology | Radiation Injuries - prevention & control | Antibodies - immunology | Radiation-Protective Agents - pharmacology | Granulocyte Colony-Stimulating Factor - immunology | Vitamin E - pharmacology | Viral antibodies | Antibodies | Macrophage colony stimulating factor | Granulocyte colony-stimulating factor | Nuclear radiation
Hematopoietic tissue | Gamma tocotrienol | Mice | Gamma radiation | Radioprotection | TOTAL-BODY IRRADIATION | PROGENITOR CELLS | MULTILINEAGE HEMATOPOIETIC RECOVERY | BIOCHEMISTRY & MOLECULAR BIOLOGY | PERIPHERAL-BLOOD | IMMUNOLOGY | INDUCED MYELOSUPPRESSION | CELL BIOLOGY | NONHUMAN PRIMATE MODEL | FACTOR G-CSF | RECEPTOR AGONIST | SUPEROXIDE-DISMUTASE | TOCOPHEROL SUCCINATE | Antibodies, Neutralizing | Granulocyte Colony-Stimulating Factor - blood | Vitamin E - analogs & derivatives | Male | Whole-Body Irradiation - adverse effects | Animals | Chromans - pharmacology | Radiation Injuries - prevention & control | Antibodies - immunology | Radiation-Protective Agents - pharmacology | Granulocyte Colony-Stimulating Factor - immunology | Vitamin E - pharmacology | Viral antibodies | Antibodies | Macrophage colony stimulating factor | Granulocyte colony-stimulating factor | Nuclear radiation
Journal Article