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Cancer Cell, ISSN 1535-6108, 06/2012, Volume 21, Issue 6, pp. 822 - 835
Cancer-associated inflammation is thought to be a barrier to immune surveillance, particularly in pancreatic ductal adenocarcinoma (PDA). Gr-1 CD11b cells are... 
OVEREXPRESSION | MICROENVIRONMENT | ONCOLOGY | DUCTAL ADENOCARCINOMA | INTERLEUKIN-1-BETA | MICE | SUPPRESSOR-CELLS | INDUCTION | DIFFERENTIATION | MAMMARY CARCINOMAS | MOUSE MODELS | CELL BIOLOGY | Immunohistochemistry | Adenocarcinoma - pathology | CD8-Positive T-Lymphocytes - pathology | Pancreatic Neoplasms - metabolism | Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Humans | Carcinoma, Pancreatic Ductal - metabolism | Inflammation - metabolism | Adenocarcinoma - metabolism | RNA Interference | T-Lymphocytes - metabolism | Myeloid Cells - immunology | CD8-Positive T-Lymphocytes - metabolism | T-Lymphocytes - pathology | Carcinoma, Pancreatic Ductal - immunology | CD11b Antigen - immunology | Adenocarcinoma - immunology | Pancreatic Neoplasms - pathology | Receptors, Chemokine - metabolism | Mice, Transgenic | Inflammation - immunology | Receptors, Chemokine - immunology | Carcinoma, Pancreatic Ductal - pathology | Granulocyte-Macrophage Colony-Stimulating Factor - genetics | Mice, Knockout | Tumor Microenvironment - immunology | Models, Immunological | Animals | Granulocyte-Macrophage Colony-Stimulating Factor - immunology | Pancreatic Neoplasms - immunology | Cell Line, Tumor | Myeloid Cells - metabolism | T-Lymphocytes - immunology | Mice | CD11b Antigen - metabolism | Myeloid Cells - pathology | CD8-Positive T-Lymphocytes - immunology | Medical colleges | Analysis | Pancreatic cancer | Oncology, Experimental | Genetically modified organisms | Inflammation | Macrophage colony stimulating factor | Research | T cells | Tumors | Cancer | Index Medicus | granulocyte-macrophage colony stimulating factor | myeloid cells | T lymphocyte | carcinoma | pancreas
Journal Article
Immunity, ISSN 1074-7613, 07/2015, Volume 43, Issue 1, pp. 187 - 199
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 10/2009, Volume 180, Issue 7, pp. 640 - 648
Journal Article
Journal Article
Lancet Oncology, ISSN 1470-2045, 2012, Volume 13, Issue 5, pp. 509 - 517
Journal Article
Journal Article
Immunity, ISSN 1074-7613, 08/2018, Volume 49, Issue 2, pp. 275 - 287.e5
Airway epithelial cells (AECs) secrete innate immune cytokines that regulate adaptive immune effector cells. In allergen-sensitized humans and mice, the airway... 
CSF1R | colony stimulating factor 1 | CSF1 | IgE | airway epithelial cells | asthma | airway dendritic cells | interferon regulatory factor 4 | immunoglobulin E | IRF4 | CSF1 receptor | allergic sensitization | conventional dendritic cells type 2 | cDC2 | IMMUNITY | INFLUENZA-A VIRUS | DENDRITIC CELLS | MACROPHAGES | LYMPH-NODES | ASTHMA | FLOW-CYTOMETRIC ANALYSIS | IMMUNOLOGY | HOUSE-DUST MITE | MONONUCLEAR PHAGOCYTES | LUNG INFLAMMATION | Dendritic Cells - immunology | Humans | Th2 Cells - immunology | Receptors, CCR7 - biosynthesis | Cell Movement - immunology | Immunoglobulin E - immunology | Allergens - immunology | Respiratory Mucosa - immunology | Epithelial Cells - cytology | Cell Line | Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - antagonists & inhibitors | Respiratory Mucosa - cytology | Mice, Inbred C57BL | Mice, Transgenic | Lymph Nodes - cytology | Macrophage Colony-Stimulating Factor - immunology | Immunity, Innate - immunology | Dendritic Cells - classification | Interferon Regulatory Factors - immunology | Animals | Up-Regulation - immunology | Epithelial Cells - immunology | RAW 264.7 Cells | Mice | Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Allergy | Allergens | Dendritic cells | Immunoglobulin E | Interferon | Biological response modifiers | Allergic reaction | CC chemokine receptors | Cdc2 protein | Leukocyte migration | Epithelial cells | Lung | Effector cells | Lymphocytes T | Lymph nodes | Respiratory tract | Colony-stimulating factor | Alveoli | Antigens | Cytokines | Colonies | CCR7 protein | Fluid | Inflammation | T cell receptors | Grants | Allergies | Asthma | Drainage | Interferon regulatory factor 4 | Ligands | Software | Chemokines | Cell migration | Interferon regulatory factor | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 07/2014, Volume 74, Issue 18, pp. 5057 - 5069
Cancer immunotherapy generally offers limited clinical benefit without coordinated strategies to mitigate the immunosuppressive nature of the tumor... 
ACTIVATION | INHIBITION | MICROENVIRONMENT | ONCOLOGY | ADENOCARCINOMA | INFLAMMATION | KINASE | CSF | POLARIZATION | IPILIMUMAB | PROGRESSION | Receptor, Macrophage Colony-Stimulating Factor - antagonists & inhibitors | Immunotherapy - methods | Receptor, Macrophage Colony-Stimulating Factor - immunology | Adenocarcinoma - pathology | Macrophage Colony-Stimulating Factor - biosynthesis | Mannose-Binding Lectins - biosynthesis | Tissue Array Analysis | Humans | Lectins, C-Type - immunology | Tumor Microenvironment | Deoxycytidine - pharmacology | Lectins, C-Type - biosynthesis | Female | Receptors, Cell Surface - biosynthesis | Carcinoma, Pancreatic Ductal - immunology | Macrophages - immunology | Signal Transduction | Macrophage Colony-Stimulating Factor - antagonists & inhibitors | Adenocarcinoma - immunology | Mice, Inbred C57BL | Pancreatic Neoplasms - pathology | Carcinoma, Pancreatic Ductal - therapy | Random Allocation | Carcinoma, Pancreatic Ductal - pathology | Receptors, Cell Surface - immunology | Macrophage Colony-Stimulating Factor - immunology | Animals | Mannose-Binding Lectins - immunology | Pancreatic Neoplasms - immunology | T-Lymphocytes - immunology | Mice | Deoxycytidine - analogs & derivatives | Cohort Studies | Pancreatic Neoplasms - therapy | Index Medicus | macrophage | chemoresistance | pancreatic cancer | cytokines | innate immunity | immune checkpoint
Journal Article