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Journal of Immunology, ISSN 0022-1767, 04/2015, Volume 194, Issue 7, pp. 3259 - 3266
Helicobacter pylori infection triggers chronic inflammation of the gastric mucosa that may progress to gastric cancer. The hypoxia-inducible factors (HIFs) are... 
ACTIVATION | HYPOXIA-INDUCIBLE FACTOR-1-ALPHA | NITRIC-OXIDE SYNTHASE | MACROPHAGES | HOST | INFECTION | MICE | KAPPA-B | HIF-1-ALPHA | IMMUNOLOGY | EXPRESSION | Helicobacter pylori - immunology | Gastric Mucosa - microbiology | Gastritis - metabolism | Humans | Gastric Mucosa - pathology | Helicobacter Infections - complications | Gastric Mucosa - metabolism | Hypoxia-Inducible Factor 1 - metabolism | Gastritis - etiology | Basic Helix-Loop-Helix Transcription Factors - metabolism | Gastritis - pathology | Myeloid Cells - immunology | Inflammation Mediators - metabolism | Helicobacter Infections - metabolism | Neutrophils - microbiology | Cytokines - genetics | Neutrophils - metabolism | Macrophages - immunology | Macrophages - microbiology | Disease Models, Animal | Cytokines - metabolism | Neutrophils - immunology | Mice, Transgenic | Helicobacter Infections - immunology | Helicobacter Infections - genetics | Gastric Mucosa - immunology | Macrophages - metabolism | Animals | Biopsy | Myeloid Cells - metabolism | Mice | Inflammation Mediators/metabolism | Macrophages/microbiology | Helicobacter Infections/genetics | Macrophages/metabolism | Neutrophils/microbiology | Macrophages/immunology | Gastritis/metabolism | Cellular Biology | Myeloid Cells/immunology | Life Sciences | Basic Helix-Loop-Helix Transcription Factors/metabolism | Neutrophils/immunology | Cytokines/genetics | Cytokines/metabolism | Cell Behavior | Helicobacter pylori/immunology | Hypoxia-Inducible Factor 1/metabolism | Neutrophils/metabolism | Gastric Mucosa/immunology | Gastritis/etiology | Helicobacter Infections/metabolism | Bacteriology | Gastritis/pathology | Microbiology and Parasitology | Gastric Mucosa/microbiology | Helicobacter Infections/immunology | Helicobacter Infections/complications | Gastric Mucosa/metabolism | Myeloid Cells/metabolism | Gastric Mucosa/pathology
Journal Article
Nature Immunology, ISSN 1529-2908, 02/2016, Volume 17, Issue 2, pp. 140 - 149
Innate sensing of pathogens initiates inflammatory cytokine responses that need to be tightly controlled. We found here that after engagement of Toll-like... 
TRANSREPRESSION | PATHWAYS | CONJUGATION | INTERFERON | ACTIVATION | SUMO | BETA-GENE | NEGATIVE REGULATION | MACROPHAGES | ENHANCER | IMMUNOLOGY | Chromatin - metabolism | Dendritic Cells - immunology | Gene Expression Profiling | Genetic Loci | Shock, Septic - immunology | Lipopolysaccharides - immunology | Shock, Septic - metabolism | Inflammation - metabolism | Inflammation Mediators - metabolism | Toll-Like Receptors - metabolism | Dendritic Cells - metabolism | Disease Models, Animal | Receptor, Interferon alpha-beta - metabolism | Shock, Septic - genetics | Sumoylation - genetics | Disease Resistance | Disease Susceptibility | Cytokines - metabolism | Signal Transduction | Immunomodulation | Gene Expression Regulation | Inflammation - virology | Inflammation - immunology | Immunity, Innate | Mice, Knockout | Animals | Enhancer Elements, Genetic | Interferon-beta - metabolism | Regulatory Elements, Transcriptional | Sumoylation - immunology | Inflammation - genetics | Protein Binding | Mice | SUMO-1 Protein - metabolism | Chromatin - genetics | Analysis | Influence | Interferon | Inflammation | Research | Biological response modifiers | Gene expression | Health aspects | Risk factors | Shock, Septic/metabolism | Inflammation Mediators/metabolism | Sumoylation/immunology | Interferon-beta/metabolism | Dendritic Cells/metabolism | Inflammation/virology | Inflammation/immunology | Life Sciences | Immunology | Receptor, Interferon alpha-beta/metabolism | Inflammation/genetics | SUMO-1 Protein/metabolism | Cytokines/metabolism | Sumoylation/genetics | Chromatin/metabolism | Inflammation/metabolism | Toll-Like Receptors/metabolism | Lipopolysaccharides/immunology | Shock, Septic/immunology | Chromatin/genetics | Shock, Septic/genetics | Dendritic Cells/immunology
Journal Article
Journal Article
Molecular and cellular biology, ISSN 0270-7306, 2007, Volume 27, Issue 13, pp. 4953 - 4967
Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
CELLS | OXIDATIVE STRESS | ACTIVATED PROTEIN-KINASE | PGC-1-ALPHA | BIOCHEMISTRY & MOLECULAR BIOLOGY | GROWTH | GENE-EXPRESSION | TRANSCRIPTIONAL COACTIVATOR | DIFFERENTIATION | MICROARRAY DATA | TRANSGENIC MICE | CELL BIOLOGY | Gene Expression Regulation, Enzymologic - drug effects | Acetyltransferases - metabolism | Multienzyme Complexes - metabolism | Adipocytes - drug effects | Glucose Intolerance | AMP-Activated Protein Kinases | Oxidative Phosphorylation - drug effects | Adipose Tissue, White - cytology | Body Composition - drug effects | Isoenzymes - metabolism | Adenosine Triphosphate - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Trans-Activators - genetics | Food Deprivation | p38 Mitogen-Activated Protein Kinases - metabolism | Homeostasis - drug effects | Phosphorylation - drug effects | Protein-Serine-Threonine Kinases - metabolism | Fibroblasts - metabolism | Isoenzymes - genetics | Hydrogen Peroxide - pharmacology | Protein-Serine-Threonine Kinases - genetics | Mitochondria - metabolism | Multienzyme Complexes - genetics | Macrophages - cytology | Mitochondria - drug effects | Feeding Behavior - drug effects | Polyamines - metabolism | Macrophages - metabolism | Organ Size - drug effects | Animals | Adipocytes - metabolism | Fibroblasts - drug effects | Adipose Tissue, White - enzymology | Adipose Tissue, White - growth & development | Glucose - metabolism | Macrophages - drug effects | Trans-Activators - metabolism | Mice | Transcription Factors | Adipose Tissue, White - drug effects | Energy Metabolism - drug effects | White/cytology/drug effects/enzymology/growth | Hydrogen Peroxide/pharmacology | Macrophages/cytology/drug effects/metabolism | Mitochondria/drug effects/metabolism | Fibroblasts/drug effects/metabolism | p38 Mitogen-Activated Protein Kinases/metabolism | MEDICIN OCH HÄLSOVETENSKAP | Homeostasis/drug effects | Multienzyme Complexes/genetics/metabolism | Protein-Serine-Threonine Kinases/genetics/metabolism | Trans-Activators/genetics/metabolism | Enzymologic/drug effects | Glucose/metabolism | Adipose Tissue | Feeding Behavior/drug effects | Organ Size/drug effects | Oxidative Phosphorylation/drug effects | MEDICAL AND HEALTH SCIENCES | development | Acetyltransferases/metabolism | Adipocytes/drug effects/metabolism | Gene Expression Regulation | Adenosine Triphosphate/metabolism | Body Composition/drug effects | Polyamines/metabolism | Energy Metabolism/drug effects | Isoenzymes/genetics/metabolism | Phosphorylation/drug effects
Journal Article
Cell metabolism, ISSN 1550-4131, 2005, Volume 1, Issue 2, pp. 107 - 119
.... Here, we developed mice with targeted mutations in two related adipocyte FABPs, aP2 and mal1, to resolve their role in systemic lipid, glucose, and energy metabolism... 
LEPTIN | OXIDATION | TARGETED DISRUPTION | GLUCOSE | ENDOCRINOLOGY & METABOLISM | MUSCLE | MICE | TNF-ALPHA | WEIGHT | INDUCED INSULIN-RESISTANCE | APOLIPOPROTEIN-E | CELL BIOLOGY | Fatty Acid-Binding Proteins | Phosphorylation | Body Weight | Adipose Tissue - cytology | Multienzyme Complexes - metabolism | Adipocytes - cytology | Immunoblotting | RNA, Messenger - metabolism | AMP-Activated Protein Kinases | Oxygen - metabolism | Tissue Distribution | Adipose Tissue - metabolism | Time Factors | Fatty Acids - metabolism | Protein-Serine-Threonine Kinases - metabolism | Cytokines - metabolism | Liver - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Insulin Resistance | Diabetes Mellitus - metabolism | Lipid Metabolism | Mice, Transgenic | Inflammation | Macrophages - cytology | Obesity - metabolism | Triglycerides - metabolism | Insulin - metabolism | Macrophages - metabolism | Phenotype | Animals | Carrier Proteins - metabolism | Adipocytes - metabolism | Glucose - metabolism | Stearoyl-CoA Desaturase - metabolism | Receptor, Insulin - metabolism | Arteriosclerosis - metabolism | Mice | Mutation | Type 2 diabetes | Obesity | Glucose | Macrophages | Fatty acids | Dextrose | Glucose metabolism | Atherosclerosis | Physiological aspects | Insulin resistance | Binding proteins | Public health | Protein binding | Diabetes therapy
Journal Article
Science (American Association for the Advancement of Science), ISSN 1095-9203, 2010, Volume 328, Issue 5985, pp. 1570 - 1573
Cholesterol metabolism is tightly regulated at the cellular level. Here we show that miR-33, an intronic microRNA (miRNA... 
MicroRNA | Hepatocytes | HDL lipoproteins | Liver | Genes | REPORTS | Homeostasis | Gene expression regulation | Macrophages | Cholesterols | Endothelial cells | TANGIER-DISEASE | HDL | LIPID-METABOLISM | CASSETTE TRANSPORTER 1 | CELLULAR CHOLESTEROL | MULTIDISCIPLINARY SCIENCES | IN-VIVO | MUTATIONS | ATP Binding Cassette Transporter, Sub-Family G, Member 1 | Membrane Glycoproteins - metabolism | Cholesterol, Dietary - administration & dosage | Lipoproteins - genetics | Lipoproteins, HDL - blood | Humans | Lipoproteins, HDL - metabolism | MicroRNAs - metabolism | Transfection | ATP-Binding Cassette Transporters - genetics | Dietary Fats - administration & dosage | Lipoproteins - metabolism | ATP-Binding Cassette Transporters - metabolism | Sterol Regulatory Element Binding Protein 2 - genetics | Sterol Regulatory Element Binding Protein 2 - metabolism | ATP Binding Cassette Transporter 1 | Cell Line | Introns | Liver - metabolism | Mice, Inbred C57BL | Gene Expression Regulation | Apolipoprotein A-I - metabolism | Cholesterol - metabolism | Membrane Glycoproteins - genetics | Proteins - genetics | Carrier Proteins - genetics | Macrophages - metabolism | Animals | Carrier Proteins - metabolism | Proteins - metabolism | Mice | MicroRNAs - genetics | Hypercholesterolemia - genetics | Macrophages, Peritoneal - metabolism | Hypercholesterolemia - metabolism | Physiological aspects | Control | Research | High density lipoproteins | Cholesterol metabolism | Lipoproteins | Cellular biology | Ribonucleic acid--RNA | Gene expression | Cholesterol
Journal Article
Immunity (Cambridge, Mass.), ISSN 1074-7613, 2013, Volume 38, Issue 5, pp. 1038 - 1049
Journal Article
The Journal of immunology (1950), ISSN 1550-6606, 2011, Volume 186, Issue 11, pp. 6553 - 6561
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 01/2014, Volume 192, Issue 2, pp. 623 - 629
.... Although the precise origin of the unchecked inflammatory response in obesity is unclear, it is known that overproduction of proinflammatory cytokines by innate immune cells affects metabolism... 
IMMUNE-SYSTEM | INFLAMMATION | DISEASE | RESISTANCE | FAT | AKT | IMMUNOLOGY | DIET-INDUCED OBESITY | KEY PLAYERS | ADIPOSE-TISSUE | CUTTING EDGE | Tumor Necrosis Factor-alpha - metabolism | Antigens, CD - immunology | T-Lymphocytes, Regulatory - metabolism | Epithelial Cells - metabolism | TOR Serine-Threonine Kinases - metabolism | Obesity - immunology | Insulin - immunology | Interferon-gamma - metabolism | Antigens, CD - metabolism | T-Lymphocytes, Regulatory - immunology | Epithelium - immunology | Signal Transduction - immunology | Inflammation - metabolism | Tumor Necrosis Factor-alpha - immunology | Interleukin-10 - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Receptor, Insulin - immunology | Macrophages - immunology | Hyperinsulinism - metabolism | Intra-Abdominal Fat - immunology | Transforming Growth Factor beta - immunology | Epithelium - metabolism | Mice, Inbred C57BL | Apyrase - metabolism | Cells, Cultured | Apyrase - immunology | CTLA-4 Antigen - metabolism | Inflammation - immunology | CTLA-4 Antigen - immunology | Intra-Abdominal Fat - metabolism | Obesity - metabolism | TOR Serine-Threonine Kinases - immunology | Insulin - metabolism | Macrophages - metabolism | Animals | Hyperinsulinism - immunology | Proto-Oncogene Proteins c-akt - immunology | Epithelial Cells - immunology | Interferon-gamma - immunology | Interleukin-10 - antagonists & inhibitors | Receptor, Insulin - metabolism | Mice | Interleukin-10 - immunology | Transforming Growth Factor beta - metabolism
Journal Article
Diabetes care, ISSN 1935-5548, 2010, Volume 33, Issue 4, pp. 861 - 868
Journal Article