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Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 2/2011, Volume 108, Issue 6, pp. 2390 - 2395
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 01/2009, Volume 206, Issue 1, pp. 79 - 87
Influenza virus infection is recognized by the innate immune system through Toll like receptor (TLR) 7 and retinoic acid inducible gene I. These two... 
MEDICINE, RESEARCH & EXPERIMENTAL | STRANDED-RNA | DYING CELLS | HUMAN MACROPHAGES | INTERLEUKIN-1-BETA | INFECTION | IMMUNOLOGY | A-VIRUS | CASPASE-1 ACTIVATION | CRYOPYRIN/NALP3 | T-CELLS | NALP3 INFLAMMASOME | CD8-Positive T-Lymphocytes - cytology | Cytoskeletal Proteins - genetics | NLR Family, Pyrin Domain-Containing 3 Protein | Dendritic Cells - immunology | Receptors, Interleukin-1 - genetics | Immunity, Innate - genetics | Cell Movement - genetics | Orthomyxoviridae - immunology | Orthomyxoviridae Infections - genetics | CD4-Positive T-Lymphocytes - immunology | Cell Movement - immunology | Lung - virology | Interleukin-1beta - metabolism | Apoptosis Regulatory Proteins - genetics | Lung - metabolism | Dendritic Cells - virology | Dendritic Cells - metabolism | Macrophages, Alveolar - immunology | Macrophages, Alveolar - virology | Antibody Formation - immunology | Immunity, Cellular - genetics | CD4-Positive T-Lymphocytes - cytology | Mice, Inbred C57BL | Mice, Knockout | Carrier Proteins - genetics | Immunity, Cellular - immunology | Immunity, Innate - immunology | Immunoglobulin Isotypes - blood | Animals | Caspase 1 - genetics | CARD Signaling Adaptor Proteins | Survival Analysis | Nasal Lavage Fluid - immunology | Immunoglobulin Isotypes - immunology | Mice | Macrophages, Alveolar - metabolism | CD8-Positive T-Lymphocytes - immunology | Orthomyxoviridae Infections - virology | Lung - immunology | Orthomyxoviridae Infections - immunology | Calcium-Binding Proteins - genetics | Multiprotein Complexes - immunology | Brief Definitive Reports
Journal Article
Journal of Virology, ISSN 0022-538X, 2016, Volume 90, Issue 6, pp. 2756 - 2766
Journal Article
PLoS Pathogens, ISSN 1553-7366, 09/2013, Volume 9, Issue 9, p. e1003615
Respiratory virus infections, such as influenza, typically induce a robust type I (pro-inflammatory cytokine) immune response, however, the production of type... 
LUNG | EOSINOPHILS | MICROBIOLOGY | T(H)2-TYPE RESPONSES | INTERLEUKIN-5 | CD8(+) T-CELLS | ADAPTIVE IMMUNITY | IL-1-LIKE CYTOKINE IL-33 | VIROLOGY | IN-VIVO | TYPE-2 IMMUNITY | RESPIRATORY SYNCYTIAL VIRUS | PARASITOLOGY | Influenza A Virus, H1N1 Subtype - immunology | Up-Regulation | Eosinophils - metabolism | Macrophages, Alveolar - pathology | Killer Cells, Natural - pathology | Eosinophils - immunology | Interleukins - metabolism | Protein Subunits - metabolism | Receptors, Interleukin - metabolism | Lung - virology | Killer Cells, Natural - immunology | Eosinophils - pathology | Lung - metabolism | Respiratory Tract Infections - virology | Macrophages, Alveolar - immunology | Respiratory Tract Infections - pathology | Macrophages, Alveolar - virology | Eosinophilia - etiology | Lung - pathology | Respiratory Tract Infections - metabolism | Specific Pathogen-Free Organisms | Interleukin-33 | Interleukin-5 - metabolism | Killer Cells, Natural - virology | Orthomyxoviridae Infections - metabolism | Eosinophils - virology | Mice, Inbred C57BL | Orthomyxoviridae Infections - pathology | Cells, Cultured | Immunity, Innate | Mice, Knockout | Animals | Respiratory Tract Infections - immunology | Mice, Inbred BALB C | Killer Cells, Natural - metabolism | Macrophages, Alveolar - metabolism | Orthomyxoviridae Infections - virology | Lung - immunology | Orthomyxoviridae Infections - immunology | Killer cells | Interleukins | Influenza | Physiological aspects | Host-parasite relationships | Research | Health aspects | T cell receptors | Immunology | Lungs | Rodents | Immune system
Journal Article
Journal of Immunology, ISSN 0022-1767, 02/2017, Volume 198, Issue 4, pp. 1616 - 1626
Human infections with highly pathogenic avian influenza A (H5N1) virus are frequently fatal but the mechanisms of disease remain ill-defined. H5N1 infection is... 
A H5N1 | NONHUMAN-PRIMATES | UNITED-STATES | EPITHELIAL-CELLS | DENDRITIC CELLS | HUMAN MACROPHAGES | DISEASE SEVERITY | IMMUNOLOGY | RHESUS MACAQUE | PATHOGENIC AVIAN INFLUENZA | IN-VIVO CHARACTERIZATION | Macrophages, Alveolar - pathology | Respiratory Distress Syndrome, Adult - physiopathology | Influenza A Virus, H5N1 Subtype - physiology | Orthomyxoviridae Infections - physiopathology | Alveolar Epithelial Cells - virology | Macaca fascicularis | Alveolar Epithelial Cells - immunology | Respiratory Distress Syndrome, Adult - immunology | Lung - virology | Alveolar Epithelial Cells - pathology | Macrophages, Alveolar - immunology | Cytokines - immunology | Disease Models, Animal | Macrophages, Alveolar - virology | Cells, Cultured | Pneumonia, Viral - immunology | Immunity, Innate - immunology | Animals | Virus Replication | Influenza A Virus, H5N1 Subtype - immunology | Respiratory Distress Syndrome, Adult - virology | Aerosols | Pulmonary Alveoli - virology | Influenza A Virus, H5N1 Subtype - pathogenicity | Orthomyxoviridae Infections - virology | Pneumonia, Viral - virology | Cytokines - biosynthesis | Lung - immunology | Orthomyxoviridae Infections - immunology | Pandemics | Epithelial cells | Viruses | Infections | Macrophages | Avian flu | Respiratory tract | Proteins | Inoculation | Primates | Alveoli | Trachea | Cytokines | Leukocytes (neutrophilic) | Exposure | Inflammation | Fatal | Inhalation | Respiratory distress syndrome | Lungs | Influenza | Replication | Interferon | Respiration | Apoptosis
Journal Article
Journal of Immunology, ISSN 0022-1767, 2011, Volume 186, Issue 2, pp. 1022 - 1031
Journal Article
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 10/2014, Volume 51, Issue 4, pp. 502 - 515
Human metapneumovirus (hMPV) and respiratory syncytial virus (RSV) are leading causes of upper and lower respiratory tract infections in young children and... 
Respiratory syncytial virus | Pathogenesis | Alveolar macrophages | Viral infection | Human metapneumovirus | Pneumonia - physiopathology | Humans | Respiratory Syncytial Viruses - immunology | Respiratory Syncytial Virus Infections - metabolism | Respiratory Syncytial Virus Infections - immunology | Airway Obstruction - virology | Paramyxoviridae Infections - physiopathology | Lung - virology | Paramyxoviridae Infections - virology | Time Factors | Airway Obstruction - immunology | Respiratory Syncytial Virus Infections - physiopathology | Inflammation Mediators - metabolism | Respiratory Syncytial Virus Infections - prevention & control | Pneumonia - immunology | Lung - metabolism | Respiratory Syncytial Virus Infections - virology | Macrophages, Alveolar - immunology | Disease Models, Animal | Macrophages, Alveolar - virology | Metapneumovirus - immunology | Cytokines - metabolism | Paramyxoviridae Infections - metabolism | Metapneumovirus - pathogenicity | Airway Obstruction - physiopathology | Cells, Cultured | Lung - physiopathology | Pneumonia - virology | Paramyxoviridae Infections - immunology | Animals | Virus Replication | Mice, Inbred BALB C | Macrophages, Alveolar - metabolism | Lung - immunology | Respiratory Syncytial Viruses - pathogenicity | viral infection | DENDRITIC CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | alveolar macrophages | AIRWAY INFLAMMATION | VIRAL-INFECTION | HOSPITALIZED CHILDREN | CELL BIOLOGY | pathogenesis | GROWTH-FACTOR-BETA | T-CELL RESPONSES | EPITHELIAL-CELLS | RESPIRATORY SYSTEM | IMMUNE-RESPONSES | PULMONARY TUBERCULOSIS | human metapneumovirus | respiratory syncytial virus | YOUNG-CHILDREN | Studies | Airway management | Disease | Lungs | Rodents | Infections | Viral infections | Immune system | Apoptosis | Original Research
Journal Article
Mucosal Immunology, ISSN 1933-0219, 2014, Volume 7, Issue 5, pp. 1116 - 1126
Journal Article