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1. Full Text Osmotic and stimulant laxatives for the management of childhood constipation
by Gordon, Morris and Macdonald, John K and Parker, Claire E and Akobeng, Anthony K and Thomas, Adrian G
Cochrane Database of Systematic Reviews, ISSN 1469-493X, 08/2016, Volume 2016, Issue 8, p. CD009118
Background Constipation within childhood is an extremely common problem. Despite the widespread use of osmotic and stimulant laxatives by health professionals... 
CONTROLLED-TRIAL | MAGNESIUM-HYDROXIDE | Dietary Fiber [adverse effects; therapeutic use] | Humans | Child, Preschool | Infant | PSYLLIUM FIBER | Osmosis | Mineral Oil [adverse effects; therapeutic use] | MEDICINE, GENERAL & INTERNAL | Polyethylene Glycols [adverse effects; therapeutic use] | POLYETHYLENE-GLYCOL 3350 | Child | Lactulose [adverse effects; therapeutic use] | HYDROLYZED GUAR GUM | PLUS ELECTROLYTES | Laxatives [adverse effects; therapeutic use] | LIQUID PARAFFIN | Constipation [drug therapy] | Magnesium Hydroxide [adverse effects; therapeutic use] | Randomized Controlled Trials as Topic | Defecation [drug effects; physiology] | CHRONIC FUNCTIONAL CONSTIPATION | Sugar Alcohols [adverse effects; therapeutic use] | Adolescent | DOUBLE-BLIND | RECTAL FECAL IMPACTION | Lactulose - adverse effects | Defecation - drug effects | Polyethylene Glycols - adverse effects | Laxatives - therapeutic use | Magnesium Hydroxide - adverse effects | Polyethylene Glycols - therapeutic use | Sugar Alcohols - therapeutic use | Laxatives - adverse effects | Sugar Alcohols - adverse effects | Magnesium Hydroxide - therapeutic use | Dietary Fiber - therapeutic use | Mineral Oil - adverse effects | Dietary Fiber - adverse effects | Mineral Oil - therapeutic use | Defecation - physiology | Constipation - drug therapy | Lactulose - therapeutic use
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2. Full Text Osmotic and stimulant laxatives for the management of childhood constipation
by Gordon, Morris and Naidoo, Khimara and Akobeng, Anthony K and Thomas, Adrian G
Cochrane database of systematic reviews (Online), ISSN 1469-493X, 2012, Volume 7, Issue 7, p. CD009118
Background Constipation within childhood is an extremely common problem. Despite the widespread use of osmotic and stimulant laxatives by health professionals... 
MEDICINE, GENERAL & INTERNAL | FECAL IMPACTION | LACTULOSE | PLUS ELECTROLYTES | CHRONIC FUNCTIONAL CONSTIPATION | LIQUID PARAFFIN | LAVAGE SOLUTION | DOUBLE-BLIND | POLYETHYLENE-GLYCOL 3350 | MINERAL-OIL | CHILDREN | Humans | Child, Preschool | Polyethylene Glycols - adverse effects | Infant | Male | Laxatives - therapeutic use | Osmosis | Polyethylene Glycols - therapeutic use | Laxatives - adverse effects | Senna Extract - therapeutic use | Dietary Fiber - therapeutic use | Senna Extract - adverse effects | Mineral Oil - adverse effects | Dietary Fiber - adverse effects | Mineral Oil - therapeutic use | Female | Constipation - drug therapy | Lactulose - therapeutic use | Child | Infant, Newborn | Lactulose - adverse effects | Defecation - drug effects | Treatment Outcome | Magnesium Hydroxide - adverse effects | Enema | Randomized Controlled Trials as Topic | Magnesium Hydroxide - therapeutic use | Adolescent
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3. Full Text Subcellular compartment targeting of layered double hydroxide nanoparticles
by Xu, Zhi Ping and Niebert, Marcus and Porazik, Katharina and Walker, Tara L and Cooper, Helen M and Middelberg, Anton P.J and Gray, Peter P and Bartlett, Perry F and Lu, Gao Qing (Max)
Journal of Controlled Release, ISSN 0168-3659, 2008, Volume 130, Issue 1, pp. 86 - 94
Current investigations show that layered double hydroxide (LDH) nanoparticles have high potential as effective non-viral agents for cellular drug delivery due... 
Cellular uptake | Clathrin-mediated endocytosis | Subcellular compartment targeting | Morphology | Layered double hydroxides | CELLS | SIMIAN-VIRUS-40 | morphology | MECHANISM | DRUG-DELIVERY | CELLULAR DELIVERY | HYDROTALCITE-LIKE COMPOUNDS | CHEMISTRY, MULTIDISCIPLINARY | cellular uptake | clathrin-mediated endocytosis | INTERNALIZATION | layered double hydroxides | PHARMACOLOGY & PHARMACY | ENDOCYTIC VESICLES | CAVEOLAE | subcellular compartment targeting | NONVIRAL VECTORS | Drug Carriers - adverse effects | NIH 3T3 Cells | Cricetulus | Nanoparticles - chemistry | Nanoparticles - adverse effects | Drug Carriers - chemistry | Magnesium Hydroxide - chemistry | Fluorescein-5-isothiocyanate - chemistry | Aluminum Hydroxide - chemistry | Drug-Related Side Effects and Adverse Reactions | Pharmaceutical Preparations - administration & dosage | Hydroxides - adverse effects | CHO Cells | Cell Survival - drug effects | Gene Transfer Techniques | Cricetinae | Hydroxides - chemistry | Endocytosis - drug effects | Subcellular Fractions - metabolism | Clathrin - metabolism | Particle Size | Microscopy, Confocal | Animals | Pharmaceutical Preparations - chemistry | Mice | Drugs | Nanoparticles | Drug delivery systems | Hydroxides | Fluorescein | Nanotechnology | Vehicles | Index Medicus
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4. Full Text The immunobiology of aluminium adjuvants: how do they really work?
by Exley, Christopher and Siesjö, Peter and Eriksson, Håkan and Neurosurgery and Neurokirurgi and Lund University and Lunds universitet
Trends in Immunology, ISSN 1471-4906, 2010, Volume 31, Issue 3, pp. 103 - 109
Aluminium adjuvants potentiate the immune response, thereby ensuring the potency and efficacy of typically sparingly available antigen. Their concomitant... 
Allergy and Immunology | MAGNESIUM | CELLS | ACTIVATION | CYTOKINE PRODUCTION | HYDROXIDE ADJUVANT | MECHANISM | IMMUNE-RESPONSES | MONOCLONAL-ANTIBODY | IMMUNOLOGY | BRAIN | NALP3 INFLAMMASOME | Adjuvants, Immunologic - pharmacology | Aluminum Compounds - adverse effects | Reactive Oxygen Species - metabolism | Humans | Muscle, Skeletal - metabolism | Magnesium Compounds - immunology | Vaccines - metabolism | Adjuvants, Immunologic - adverse effects | T-Lymphocytes - drug effects | Adenosine Triphosphate - metabolism | Inflammation Mediators - metabolism | Aluminum Hydroxide - pharmacology | Adaptive Immunity - immunology | Phosphates - pharmacology | Magnesium Compounds - pharmacology | Phosphates - immunology | Aluminum Hydroxide - metabolism | Antigen-Presenting Cells - metabolism | Immunity, Innate - drug effects | Oxidation-Reduction | Phagocytes - drug effects | Antigen-Presenting Cells - drug effects | Vaccines - immunology | Inflammation - immunology | Aluminum Compounds - immunology | Phagocytes - metabolism | Phagocytes - immunology | Antigen-Presenting Cells - immunology | Inflammation - etiology | Aluminum Compounds - metabolism | Magnesium Compounds - metabolism | B-Lymphocytes - drug effects | Immunity, Innate - immunology | Extracellular Fluid - metabolism | Models, Immunological | Phosphates - metabolism | Adaptive Immunity - drug effects | Aluminum Hydroxide - adverse effects | Animals | B-Lymphocytes - immunology | Phosphates - adverse effects | Aluminum Hydroxide - immunology | T-Lymphocytes - immunology | Aluminum Compounds - pharmacology | Ligands | Immunization | Vaccines | Fluorides | Molecular weight | Clinical Medicine | Neurologi | Neurology | Medical and Health Sciences | Medicin och hälsovetenskap | Surgery | Klinisk medicin | Kirurgi
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5. Full Text Effect of metal‐cation antacids on the pharmacokinetics of 1200 mg raltegravir
by Krishna, Rajesh and East, Lilly and Larson, Patrick and Valiathan, Chandni and Butterfield, Kristin and Teng, Yang and Hernandez‐Illas, Martha
Journal of Pharmacy and Pharmacology, ISSN 0022-3573, 11/2016, Volume 68, Issue 11, pp. 1359 - 1365
Objectives Raltegravir is a human immunodeficiency virus (HIV)‐1 integrase strand transfer inhibitor currently marketed at a dose of 400 mg twice daily (BID).... 
interaction | pharmacokinetics | calcium carbonate | once‐daily | aluminium and magnesium hydroxide | once-daily | ACID-REDUCING AGENTS | THERAPY | VOLUNTEERS | PHARMACOLOGY & PHARMACY | HIV-INTEGRASE INHIBITOR | Raltegravir Potassium - adverse effects | Area Under Curve | Magnesium - administration & dosage | Humans | Middle Aged | Raltegravir Potassium - administration & dosage | Male | Metabolic Clearance Rate | Aluminum Hydroxide - administration & dosage | HIV Integrase Inhibitors - administration & dosage | Drug Interactions | Polypharmacy | Antacids - adverse effects | HIV Infections - diagnosis | Adult | Female | Calcium Carbonate - administration & dosage | Magnesium - adverse effects | Raltegravir Potassium - pharmacokinetics | Drug Administration Schedule | Administration, Oral | HIV Infections - virology | HIV Integrase Inhibitors - pharmacokinetics | Magnesium Hydroxide - adverse effects | Calcium Carbonate - adverse effects | Aluminum Hydroxide - adverse effects | Magnesium Hydroxide - administration & dosage | HIV Integrase Inhibitors - adverse effects | Raltegravir Potassium - blood | HIV Infections - drug therapy | HIV Integrase Inhibitors - blood | Antacids - administration & dosage | Drug Combinations | Urine | Antiviral agents | Analysis | Electrocardiogram | Calcium carbonate | Electrocardiography | Magnesium hydroxide | HIV (Viruses) | Human immunodeficiency virus--HIV | Antacids | Magnesium
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6. Full Text Hydrotalcite composites for an effective fluoride buccal administration: A new technological approach
by Perioli, Luana and Nocchetti, Morena and Giannelli, Paola and Pagano, Cinzia and Bastianini, Maria
International Journal of Pharmaceutics, ISSN 0378-5173, 09/2013, Volume 454, Issue 1, pp. 259 - 268
The aim of this work was to develop new mucoadhesive buccal patches containing an inorganic fluorinated compound, MgAl-F, intended for decay prevention.... 
Buccal patches | Hydrotalcite | Fluoride | Mucoadhesion | Decay | TOOTH ENAMEL | DENTAL-CARIES | PHARMACOLOGY & PHARMACY | Sodium Fluoride - administration & dosage | Adhesiveness | Humans | Sodium Fluoride - chemistry | Solubility | Technology, Pharmaceutical - methods | Aluminum Hydroxide - administration & dosage | Cariostatic Agents - chemistry | Magnesium Hydroxide - adverse effects | Administration, Buccal | Cariostatic Agents - administration & dosage | Acrylic Resins - chemistry | Chemistry, Pharmaceutical | Drug Carriers | Magnesium Hydroxide - chemistry | Aluminum Hydroxide - adverse effects | Magnesium Hydroxide - administration & dosage | Fluorides, Topical - chemistry | Aluminum Hydroxide - chemistry | Carboxymethylcellulose Sodium - chemistry | Dosage Forms | Kinetics | Delayed-Action Preparations | Fluorides, Topical - administration & dosage | Composite materials industry
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7. Full Text The efficacy, safety and cost‐effectiveness of hydrotalcite versus esomeprazole in on‐demand therapy of NERD: A multicenter, randomized, open‐label study in China
by Xiao, Ying Lian and Nie, Yu Qiang and Hou, Xiao Hua and Xie, Peng Yan and Fang, Jing Yuan and Yuan, Yao Zong and Zhou, Li Ya and Zhao, Nai Qing and Chen, Min Hu
Journal of Digestive Diseases, ISSN 1751-2972, 09/2013, Volume 14, Issue 9, pp. 463 - 468
Objective The aim of the study was to investigate whether hydrotalcite was comparable to esomeprazole, a proton pump inhibitor, in on‐demand therapy for... 
non‐erosive reflux disease | effectiveness | on‐demand therapy | gastroesophageal reflux | esomeprazole sodium | hydrotalcite | Gastroesophageal reflux | Esomeprazole sodium | Non-erosive reflux disease | Hydrotalcite | On-demand therapy | Effectiveness | RABEPRAZOLE | INFECTIONS | MAINTENANCE TREATMENT | MANAGEMENT | ACID | on-demand therapy | PROTON-PUMP INHIBITOR | CONSENSUS | FAILURE | GASTROESOPHAGEAL-REFLUX DISEASE | non-erosive reflux disease | NONEROSIVE REFLUX | GASTROENTEROLOGY & HEPATOLOGY | Proton Pump Inhibitors - economics | Anti-Ulcer Agents - economics | Humans | Magnesium Hydroxide - economics | Middle Aged | Esomeprazole - adverse effects | Male | Esomeprazole - economics | Esomeprazole - therapeutic use | Antacids - therapeutic use | Young Adult | Drug Costs - statistics & numerical data | Antacids - adverse effects | Gastroesophageal Reflux - economics | Antacids - economics | Adult | Female | Drug Therapy, Combination | Gastroesophageal Reflux - drug therapy | Aluminum Hydroxide - economics | Anti-Ulcer Agents - therapeutic use | Proton Pump Inhibitors - adverse effects | Anti-Ulcer Agents - adverse effects | Aluminum Hydroxide - therapeutic use | Treatment Outcome | Magnesium Hydroxide - adverse effects | Proton Pump Inhibitors - therapeutic use | Magnesium Hydroxide - therapeutic use | Aluminum Hydroxide - adverse effects | Cost-Benefit Analysis | Adolescent | Aged
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8. Full Text Cochrane Review: Osmotic and stimulant laxatives for the management of childhood constipation (Review)
by Gordon, Morris and Naidoo, Khimara and Akobeng, Anthony K and Thomas, Adrian G
Evidence‐Based Child Health: A Cochrane Review Journal, ISSN 1557-6272, 01/2013, Volume 8, Issue 1, pp. 57 - 109
Background Constipation within childhood is an extremely common problem. Despite the widespread use of osmotic and stimulant laxatives by health professionals... 
Dietary Fiber [adverse effects; therapeutic use] | Laxatives [adverse effects; therapeutic use] | Humans | Child, Preschool | Infant | Constipation [drug therapy] | Magnesium Hydroxide [adverse effects; therapeutic use] | Randomized Controlled Trials as Topic | Defecation [drug effects; physiology] | Mineral Oil [adverse effects; therapeutic use] | Sugar Alcohols [adverse effects; therapeutic use] | Adolescent | Osmosis; Polyethylene Glycols [adverse effects; therapeutic use] | Child | Lactulose [adverse effects; therapeutic use] | Laxatives [adverse effects | drug therapy | Constipation | therapeutic use | Defecation - drug effects | Male | Treatment Outcome | Laxatives - therapeutic use | Polyethylene Glycols - therapeutic use | Senna Extract - therapeutic use | Mineral Oil - therapeutic use | Female | Constipation - drug therapy | Lactulose - therapeutic use | Infant, Newborn
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9. Full Text Magnesium Hydroxide/Aluminium Hydroxide‐Containing Antacid Does Not Affect the Pharmacokinetics of the Targeted Phosphodiesterase 4 Inhibitor Roflumilast
by Nassr, Nassr and Lahu, Gezim and Hünnemeyer, Andreas and Richter, Oliver and Knoerzer, Dietrich and Reutter, Felix and Zech, Karl and Hermann, Robert
The Journal of Clinical Pharmacology, ISSN 0091-2700, 05/2007, Volume 47, Issue 5, pp. 660 - 666
roflumilast | Mg/Al‐containing antacid | PDE4 inhibitor | drug‐drug interaction | Mg/Al-containing antacid | Roflumilast | Drug-drug interaction | HEALTHY-SUBJECTS | VOLUNTEERS | CLASSIFICATION | BIOAVAILABILITY | ALUMINUM | OBSTRUCTIVE PULMONARY-DISEASE | IN-VITRO | THERAPY | PHARMACOLOGY | PHARMACOLOGY & PHARMACY | ABSORPTION | drug-drug interaction | Cyclic Nucleotide Phosphodiesterases, Type 4 | Phosphodiesterase Inhibitors - adverse effects | Phosphodiesterase Inhibitors - pharmacokinetics | Benzamides - pharmacokinetics | Benzamides - blood | Humans | Middle Aged | Aminopyridines - pharmacokinetics | Magnesium Hydroxide - pharmacology | Cyclopropanes - blood | Male | Magnesium Hydroxide - adverse effects | Phosphodiesterase Inhibitors - blood | Cross-Over Studies | Aluminum Hydroxide - adverse effects | Drug Interactions | Aminopyridines - blood | Antacids - adverse effects | 3',5'-Cyclic-AMP Phosphodiesterases - antagonists & inhibitors | Adult | Female | Aluminum Hydroxide - pharmacology | Antacids - pharmacology | Cyclopropanes - pharmacokinetics | Lung diseases, Obstructive | Anti-inflammatory drugs | Drug interactions | Dosage and administration | Research | Chemical properties | Drug therapy | Antacids | Asthma
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10. Full Text Scrub typhus meningoencephalitis occurring during doxycycline therapy for Orientia tsutsugamushi
by Kim, Dong-Min and Kim, Yoon Seong and Cho, Hea-Young and Lee, Yong-Bok
Diagnostic Microbiology & Infectious Disease, ISSN 0732-8893, 2011, Volume 69, Issue 3, pp. 271 - 274
Abstract We report on a scrub typhus patient who contracted meningoencephalitis during doxycycline administration. This is the first case of scrub typhus in... 
Infectious Disease | Internal Medicine | Orientia tsutsugamushi | Scrub typhus | Doxycycline | DIAGNOSIS | INFECTIOUS DISEASES | PENETRATION | MICROBIOLOGY | CEREBROSPINAL-FLUID | Carbonates - adverse effects | Scrub Typhus - microbiology | Doxycycline - cerebrospinal fluid | Doxycycline - therapeutic use | Humans | Aluminum Hydroxide - therapeutic use | Male | Magnesium Hydroxide - adverse effects | Scrub Typhus - drug therapy | Antacids - therapeutic use | Anti-Bacterial Agents - therapeutic use | Doxycycline - blood | Magnesium Hydroxide - therapeutic use | Aluminum Hydroxide - adverse effects | Antacids - adverse effects | Meningoencephalitis - microbiology | Carbonates - therapeutic use | Aged | Meningoencephalitis - drug therapy
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11. Full Text The effect of a combination antacid preparation containing aluminium hydroxide and magnesium hydroxide on rosuvastatin pharmacokinetics
by Martin, Paul D and Schneck, Dennis W and Dane, Aaron L and Warwick, Michael J
Current Medical Research and Opinion, ISSN 0300-7995, 04/2008, Volume 24, Issue 4, pp. 1231 - 1235
ABSTRACT Objective: Rosuvastatin, a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor used for the treatment of dyslipidaemia, may be... 
Drug | drug interaction | Co-magaldrox | Rosuvastatin | Bioavailability | Pharmacokinetics | Antacid | ANTACID | CO-MAGALDROX | PHARMACOKINETICS | BIOAVAILABILITY | ROSUVASTATIN | DRUG-DRUG INTERACTION | Drug-drug interaction | MEDICINE, RESEARCH & EXPERIMENTAL | COA REDUCTASE INHIBITOR | antacid | ADULT MALE-VOLUNTEERS | DRUG-INTERACTIONS | CIMETIDINE | MEDICINE, GENERAL & INTERNAL | bioavailability | co-magaldrox | pharmacokinetics | HEALTHY-VOLUNTEERS | drug-drug interaction | rosuvastatin | Fluorobenzenes - pharmacokinetics | Area Under Curve | Humans | Middle Aged | Biological Availability | Male | Aluminum Hydroxide - administration & dosage | Fluorobenzenes - administration & dosage | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacokinetics | Drug Interactions | Time Factors | Antacids - adverse effects | Adult | Drug Administration Schedule | Pyrimidines - administration & dosage | Rosuvastatin Calcium | Magnesium Hydroxide - adverse effects | Sulfonamides - pharmacokinetics | Cross-Over Studies | Anticholesteremic Agents - pharmacokinetics | Aluminum Hydroxide - adverse effects | Magnesium Hydroxide - administration & dosage | Anticholesteremic Agents - administration & dosage | Pyrimidines - pharmacokinetics | Antacids - administration & dosage | Sulfonamides - administration & dosage | Index Medicus
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12. The development of severe methemoglobinemia in patients receiving "Almagel A"
by Starkov, Iu G and Kazennov, V V and Vybornyĭ, M I and Amerov, D B and Shumkina, L V
Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, ISSN 1682-8658, 2014, Issue 7, p. 91
This clinical case and the literature review show possible development of methemoglobinemia due to the use of local anesthetics, included in drugs for the... 
Humans | Aluminum Hydroxide - therapeutic use | Treatment Outcome | Aluminum Hydroxide - administration & dosage | Magnesium Hydroxide - adverse effects | Benzocaine - therapeutic use | Benzocaine - adverse effects | Magnesium Hydroxide - therapeutic use | Aluminum Hydroxide - adverse effects | Magnesium Hydroxide - administration & dosage | Benzocaine - administration & dosage | Female | Methemoglobinemia - chemically induced | Methemoglobinemia - blood | Methemoglobinemia - therapy | Drug Combinations | Methemoglobin - analysis
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13. Safety and efficacy of immediate postoperative feeding and bowel stimulation to prevent ileus after major gynecologic surgical procedures
by Fanning, James and Hojat, Rod
Journal of the American Osteopathic Association, ISSN 0098-6151, 2011, Volume 111, Issue 8, pp. 469 - 472
Postoperative ileus is a major complication of abdominal surgical procedures To evaluate the incidence of ileus and gastrointestinal morbidity in patients who... 
Cathartics - administration & dosage | Prospective Studies | Gynecologic Surgical Procedures - adverse effects | Humans | Middle Aged | Oxycodone | Male | Morphine | Ketorolac Tromethamine | Incidence | Young Adult | Time Factors | Ileus - etiology | Aged, 80 and over | Adult | Female | Length of Stay | Cathartics - adverse effects | Risk Factors | Treatment Outcome | Magnesium Hydroxide - adverse effects | Magnesium Hydroxide - administration & dosage | Acetaminophen | Anesthesia Recovery Period | Ileus - prevention & control | Aged
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14. Full Text Survey of topical oral solutions for the treatment of chemo-induced oral mucositis
by Chan, Alexandre and Ignoffo, Robert J
Journal of Oncology Pharmacy Practice, ISSN 1078-1552, 12/2005, Volume 11, Issue 4, pp. 139 - 143
Purpose. The objectives of this study were (1) to describe the usage of topical oral solutions in patients experiencing chemotherapy-induced oral mucositis... 
Oncology pharmacists | Magic mouthwash