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The Journal of immunology (1950), ISSN 1550-6606, 08/2014, Volume 193, Issue 3, pp. 1246 - 1257
Malarial infection is initiated when the sporozoite form of the Plasmodium parasite is inoculated into the skin by a mosquito. Sporozoites invade hepatocytes... 
Life Sciences & Biomedicine | Immunology | Science & Technology | Inflammation - pathology | Plasmodium berghei - immunology | Skin - cytology | Humans | CD8-Positive T-Lymphocytes - parasitology | Inflammation - parasitology | Sporozoites - immunology | Female | Injections, Intradermal | Skin - immunology | Plasmodium berghei - parasitology | Cell Line | Sporozoites - transplantation | Anopheles - parasitology | Malaria - immunology | Mice, Inbred C57BL | Skin - parasitology | Sporozoites - radiation effects | Mice, Transgenic | Host-Parasite Interactions - immunology | Inflammation - immunology | Lymph Nodes - immunology | Antigen Presentation - immunology | Hep G2 Cells | Animals | Lymph Nodes - parasitology | Ear | Malaria - parasitology | Mice | Anopheles - immunology | CD8-Positive T-Lymphocytes - immunology | Index Medicus | Abridged Index Medicus | Malaria/immunology | Antigen Presentation/immunology | Lymph Nodes/immunology | Sporozoites/transplantation | Inflammation/immunology | Life Sciences | Lymph Nodes/parasitology | CD8-Positive T-Lymphocytes/immunology | Skin/cytology | Sporozoites/radiation effects | Anopheles/immunology | Inflammation/pathology | Plasmodium berghei/parasitology | Plasmodium berghei/immunology | Inflammation/parasitology | Skin/parasitology | CD8-Positive T-Lymphocytes/parasitology | Sporozoites/immunology | Host-Parasite Interactions/immunology | Skin/immunology | Anopheles/parasitology | Malaria/parasitology
Journal Article
The Journal of immunology (1950), ISSN 1550-6606, 10/2009, Volume 183, Issue 8, pp. 5208 - 5220
The role of proinflammatory cytokine production in the pathogenesis of malaria is well established, but the identification of the parasite products that... 
Life Sciences & Biomedicine | Immunology | Science & Technology | Interleukin-1alpha - immunology | Chemokine CCL2 - immunology | NLR Family, Pyrin Domain-Containing 3 Protein | NF-kappa B - metabolism | Inflammation - parasitology | Endothelial Cells - parasitology | Extracellular Signal-Regulated MAP Kinases - immunology | Plasmodium falciparum | Interleukin-1beta - metabolism | Tumor Necrosis Factor-alpha - immunology | Interleukin-8 - metabolism | Toll-Like Receptors - metabolism | Chemokine CXCL1 - metabolism | Interleukin-6 - metabolism | Carrier Proteins - immunology | Toll-Like Receptors - immunology | Chemokine CXCL1 - immunology | Signal Transduction - drug effects | Interleukin-6 - immunology | Malaria, Falciparum - immunology | Uric Acid - antagonists & inhibitors | Mice | Interleukin-8 - immunology | Inflammation - chemically induced | Tumor Necrosis Factor-alpha - metabolism | NF-kappa B - immunology | Interleukin-1alpha - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Hemeproteins - immunology | Macrophages - parasitology | Signal Transduction - immunology | Myeloid Differentiation Factor 88 - immunology | Cytoskeletal Proteins - metabolism | Chemokine CCL2 - metabolism | Macrophages - immunology | Uric Acid - metabolism | Interleukin-1beta - immunology | Hemeproteins - pharmacology | Inflammation - immunology | Endothelial Cells - immunology | Malaria, Falciparum - parasitology | Animals | Apoptosis Regulatory Proteins | Carrier Proteins - metabolism | Cytoskeletal Proteins - immunology | CARD Signaling Adaptor Proteins | Allopurinol - pharmacology | Macrophages - drug effects | Myeloid Differentiation Factor 88 - metabolism | Interferon-gamma - pharmacology | Endothelial Cells - drug effects | Index Medicus | Abridged Index Medicus | Chemokine | TLR9 | Plasmodium | Inflammasome | NALP3 | Cytokine
Journal Article
Nature (London), ISSN 0028-0836, 01/2016, Volume 529, Issue 7584, pp. 105 - 109
Plasmodium falciparum antigens expressed on the surface of infected erythrocytes are important targets of naturally acquired immunity against malaria, but... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Antibody Specificity | Clone Cells - cytology | Receptors, Immunologic - chemistry | Antigens, Protozoan - immunology | Epitopes, B-Lymphocyte - chemistry | Humans | DNA Transposable Elements - immunology | Molecular Sequence Data | Antibodies, Monoclonal - therapeutic use | Epitopes, B-Lymphocyte - immunology | Plasmodium falciparum - immunology | Malaria Vaccines - chemistry | Clone Cells - immunology | DNA Transposable Elements - genetics | Malaria Vaccines - immunology | Protozoan Proteins - chemistry | Conserved Sequence - immunology | Receptors, Immunologic - immunology | Antigenic Variation - immunology | Antibodies, Monoclonal - chemistry | Antibodies, Monoclonal - immunology | Erythrocytes - immunology | Amino Acid Sequence | B-Lymphocytes - cytology | Collagen - immunology | Malaria - immunology | Membrane Proteins - immunology | Protein Structure, Tertiary - genetics | Kenya | Mutagenesis, Insertional - genetics | Antibodies, Monoclonal - genetics | Collagen - metabolism | B-Lymphocytes - immunology | Membrane Proteins - chemistry | Erythrocytes - metabolism | Malaria - parasitology | Erythrocytes - parasitology | Receptors, Immunologic - genetics | Protozoan Proteins - immunology | Receptors, Immunologic - metabolism | Antigen-antibody reactions | Host-parasite relationships | Genetic aspects | Malaria | Observations | Genetic variation | Antigens | Immunoglobulins | Genes | Erythrocytes | Monoclonal antibodies | Mutation | Chromosomes | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 12/2015, Volume 112, Issue 51, pp. E7128 - E7137
This paper reviews the developments that have occurred in the field of human genetics of infectious diseases from the second half of the 20th century onward.... 
Pediatrics | Immunology | Infectious diseases | Human genetics | Primary immunodeficiency | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Encephalitis, Herpes Simplex - immunology | Humans | Genetic Diseases, Inborn - genetics | Lymphoproliferative Disorders - immunology | Mycobacterium Infections - immunology | Young Adult | Pneumococcal Infections - immunology | Mycobacterium Infections - genetics | Pneumococcal Infections - genetics | Complement System Proteins - genetics | Encephalitis, Herpes Simplex - genetics | Epidermodysplasia Verruciformis - immunology | Interferon-gamma - genetics | Immunologic Deficiency Syndromes - immunology | Child | Genetic Predisposition to Disease | Neisseria - immunology | Tinea - immunology | Infection - immunology | Candidiasis, Chronic Mucocutaneous - genetics | Malaria - immunology | Candidiasis, Chronic Mucocutaneous - immunology | Genetic Diseases, Inborn - immunology | Tinea - genetics | Epidermodysplasia Verruciformis - genetics | Lymphoproliferative Disorders - genetics | Infection - genetics | Models, Immunological | Neisseria - pathogenicity | Influenza, Human - genetics | Interferon-gamma - immunology | Adolescent | Immunologic Deficiency Syndromes - genetics | Models, Genetic | Malaria - genetics | Influenza, Human - immunology | Development and progression | Genetic aspects | Disease susceptibility | Immune response | Communicable diseases | Index Medicus | Biological Sciences | human genetics | PNAS Plus | infectious diseases | pediatrics | primary immunodeficiency | immunology
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 05/2013, Volume 110, Issue 24, pp. E2209 - E2218
Microbial capsular antigens are effective vaccines but are chemically and immunologically diverse, resulting in a major barrier to their use against multiple... 
Carbohydrates | Animal models | Infectious diseases | Malaria | Immunotherapy | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Plasmodium berghei - immunology | Gram-Positive Bacteria - physiology | Acetylglucosamine - immunology | Plasmodium berghei - physiology | Bacterial Capsules - metabolism | Humans | Antibodies, Bacterial - pharmacology | Mycoses - microbiology | Host-Pathogen Interactions - drug effects | Gram-Negative Bacteria - immunology | Host-Pathogen Interactions - immunology | Fungi - immunology | Time Factors | Bacterial Infections - immunology | Immunoglobulin G - immunology | Fungi - physiology | Immunoglobulin G - pharmacology | Gram-Positive Bacteria - immunology | Gram-Negative Bacteria - physiology | Antibodies, Monoclonal - immunology | Bacterial Infections - microbiology | Staphylococcus aureus - metabolism | Mycoses - prevention & control | Opsonin Proteins - immunology | Antibodies, Monoclonal - pharmacology | Malaria - immunology | Mice, Inbred C57BL | Protein Binding - immunology | Malaria - prevention & control | Bacterial Infections - prevention & control | Animals | Malaria - parasitology | Survival Analysis | Antibodies, Bacterial - immunology | Staphylococcus aureus - immunology | Mice | Mycoses - immunology | Bacterial Capsules - immunology | Index Medicus | carbohydrates | Biological Sciences | animal models | PNAS Plus | immunotherapy | infectious diseases | malaria
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 05/2013, Volume 110, Issue 22, pp. 9090 - 9095
Journal Article