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The London School of Hygiene and Tropical Medicine: a New Century of Malaria Research, 12/2000
The global malaria situation has scarcely improved in the last 100 years, despite major advances in our knowledge of the basic biology, epidemiology and... 
malaria, genetics, vaccines, drug combinations, economics
Journal
PLoS One, ISSN 1932-6203, 2013, Volume 8, Issue 2, p. e55571
BACKGROUND: Gene-based vaccination using prime/boost regimens protects animals and humans against malaria, inducing cell-mediated responses that in animal... 
APICAL MEMBRANE ANTIGEN-1 | SPOROZOITE INOCULATION | VIRUS ANKARA | IMMUNIZATION | NEUTRALIZING ANTIBODIES | MULTIDISCIPLINARY SCIENCES | CIRCUMSPOROZOITE PROTEIN | DOUBLE-BLIND | NAIVE ADULTS | CYTOTOXIC T-LYMPHOCYTES | PHASE 2A TRIAL | Vaccines, DNA - genetics | Malaria, Falciparum - prevention & control | Antigens, Protozoan - immunology | Humans | Middle Aged | Vaccines, DNA - immunology | Male | Plasmodium falciparum - immunology | Protozoan Proteins - genetics | Young Adult | Malaria Vaccines - adverse effects | Plasmodium falciparum - genetics | Malaria Vaccines - immunology | Adult | Female | Antigens, Protozoan - genetics | Malaria Vaccines - therapeutic use | Membrane Proteins - genetics | Adenoviruses, Human - immunology | Membrane Proteins - immunology | Vaccines, DNA - therapeutic use | Malaria, Falciparum - parasitology | Interferon-gamma - immunology | Vaccines, DNA - adverse effects | Adolescent | Malaria, Falciparum - immunology | Adenoviruses, Human - genetics | CD8-Positive T-Lymphocytes - immunology | Immunity, Cellular | Protozoan Proteins - immunology | Malaria Vaccines - genetics | Antigens | Wildlife conservation | Malaria | Liver | Vaccination | Malaria vaccine | Vaccines | T cells | Plasmodium falciparum | Advertising executives | Mosquitoes | Control | Analysis | Adenoviruses | DNA | Bites and stings | Genetic aspects | Health aspects | Enzyme-linked immunosorbent assay | Flow cytometry | Animal models | Goats | CD8 antigen | Antibodies | Leukocytes (mononuclear) | Lymphocytes T | Parasites | Aquatic insects | Immunity | Immunity (cell-mediated) | Replicating | Acquired immune deficiency syndrome--AIDS | Sporozoites | Peripheral blood mononuclear cells | Deoxyribonucleic acid--DNA | Circumsporozoite protein | Expression vectors | Vector-borne diseases | Medical research | Immunization | Statistical analysis | Diarrhea | Membrane proteins | Cytometry | Plasmids | γ-Interferon | Interferon | Acquired immune deficiency syndrome | Deoxyribonucleic acid | AIDS
Journal Article
Nature Communications, ISSN 2041-1723, 11/2013, Volume 4, Issue 1, p. 2836
Journal Article
Infection, Genetics and Evolution, ISSN 1567-1348, 10/2017, Volume 54, pp. 402 - 416
Human papillomavirus (HPV)-caused cervical cancer is the fourth common female cancer globally. Despite availability of three effective vaccines in market,... 
Human papillomavirus (HPV) vaccine | Vaccine design | Minor capsid protein (L2) | Cervical cancer (CxCa) | Immunoinformatics | IMMUNE-RESPONSE | INFECTIOUS DISEASES | IN-SILICO | PROTEIN-STRUCTURE | ESCHERICHIA-COLI | SUBUNIT VACCINES | HUMAN-PAPILLOMAVIRUS VACCINES | TOLL-LIKE RECEPTORS | CROSS-NEUTRALIZING EPITOPE | SELF-ADJUVANTING ANTIGEN | FEMALE REPRODUCTIVE-TRACT | Papillomavirus Vaccines - genetics | Vaccines, Subunit - genetics | Humans | Epitopes, T-Lymphocyte - genetics | Epitopes, B-Lymphocyte - immunology | Papillomaviridae - genetics | Papillomaviridae - immunology | Epitopes, B-Lymphocyte - genetics | Flagellin - genetics | Malaria Vaccines - immunology | Capsid Proteins - immunology | Adjuvants, Immunologic - genetics | Oncogene Proteins, Viral - genetics | Epitopes, T-Lymphocyte - immunology | Computational Biology - methods | Flagellin - immunology | Vaccines, Subunit - chemistry | Vaccines, Subunit - immunology | Molecular Dynamics Simulation | Animals | Papillomavirus Vaccines - chemistry | Papillomavirus Infections - prevention & control | Papillomavirus Vaccines - immunology | Molecular Docking Simulation | Oncogene Proteins, Viral - immunology | Capsid Proteins - genetics | Malaria Vaccines - genetics | Prevention | Peptides | Viral proteins | Analysis | Molecular dynamics | Vaccines | T cells | Health aspects | Papillomavirus infections | Cervical cancer | Antigenic determinants | Cancer
Journal Article
Vaccine, ISSN 0264-410X, 2013, Volume 31, Issue 52, pp. 6216 - 6224
Journal Article
Science Translational Medicine, ISSN 1946-6234, 11/2014, Volume 6, Issue 261, pp. 261ra153 - 261ra153
A protective vaccine against hepatitis C virus (HCV) remains an unmet clinical need. HCV infects millions of people worldwide and is a leading cause of liver... 
MEDICINE, RESEARCH & EXPERIMENTAL | CHALLENGE | NEUTRALIZING ANTIBODIES | HEPATITIS-C VIRUS | SINGLE-SOURCE OUTBREAK | IMMUNE-RESPONSES | PERSISTENCE | STAGE MALARIA | CYTOKINE EXPRESSION | VIRAL CLEARANCE | ACUTE INFECTION | CELL BIOLOGY | Cell Proliferation | Hepacivirus - immunology | Viral Hepatitis Vaccines - administration & dosage | Humans | Viral Vaccines - genetics | England | Hepacivirus - genetics | Hepacivirus - pathogenicity | Healthy Volunteers | CD4-Positive T-Lymphocytes - immunology | Hepatitis C - immunology | Vaccination - methods | Time Factors | Hepatitis C Antibodies - blood | Adenoviridae - genetics | Adenoviridae - immunology | CD4-Positive T-Lymphocytes - virology | Hepatitis C - prevention & control | Interferon-gamma Release Tests | Lymphocyte Activation | Cells, Cultured | Histocompatibility Antigens Class I - immunology | Treatment Outcome | Enzyme-Linked Immunospot Assay | Pan troglodytes | Viral Vaccines - administration & dosage | Hepatitis C - diagnosis | Viral Hepatitis Vaccines - immunology | Animals | CD8-Positive T-Lymphocytes - virology | Hepatitis C - virology | Viral Hepatitis Vaccines - genetics | Immunologic Memory | CD8-Positive T-Lymphocytes - immunology | Viral Vaccines - immunology | modified vaccinia Ankara | Hepatitis | Prophylactic | Adenoviral | HCV | Vaccine | Hepatitis C Virus
Journal Article
Applied Microbiology and Biotechnology, ISSN 0175-7598, 3/2013, Volume 97, Issue 5, pp. 1987 - 1995
Journal Article
Scientific Reports, ISSN 2045-2322, 01/2016, Volume 6, Issue 1, p. 18848
Transmission-blocking vaccines (TBV) target the sexual-stages of the malaria parasite in the mosquito midgut and are widely considered to be an essential tool... 
PROTECTS MICE | OLIGOMERIZATION DOMAIN | STAGE | MULTIDISCIPLINARY SCIENCES | POXVIRUS | CANDIDATE | ANTIBODY-RESPONSES | PROTEINS | ADENOVIRUS | ADJUVANT | ANTIGEN | Immunogenicity, Vaccine | Recombinant Fusion Proteins - immunology | Malaria, Falciparum - prevention & control | Adjuvants, Immunologic - administration & dosage | Antigens, Protozoan - immunology | Germinal Center - immunology | Humans | Vaccination | Germinal Center - drug effects | Plasmodium falciparum - drug effects | Plasmodium falciparum - immunology | Protozoan Proteins - genetics | Life Cycle Stages - immunology | Pichia - metabolism | Insect Vectors - drug effects | Adjuvants, Immunologic - chemistry | Malaria Vaccines - immunology | Adenoviridae - genetics | Adjuvants, Immunologic - genetics | Antigens, Protozoan - genetics | Protozoan Proteins - administration & dosage | Adenoviridae - immunology | Recombinant Fusion Proteins - administration & dosage | Life Cycle Stages - drug effects | Gene Expression | Genetic Vectors - chemistry | Genetic Vectors - immunology | Plasmids - immunology | Culicidae - drug effects | Antibodies, Protozoan - biosynthesis | Malaria, Falciparum - parasitology | Animals | Malaria Vaccines - administration & dosage | Insect Vectors - parasitology | Malaria, Falciparum - immunology | Pichia - genetics | Plasmids - chemistry | Recombinant Fusion Proteins - genetics | Vaccines, Synthetic | Culicidae - parasitology | Mice | Mice, Inbred BALB C | Plasmodium falciparum - growth & development | Protozoan Proteins - immunology | Malaria Vaccines - genetics | Proteins | Nanoparticles | Antigens | Disease transmission | Malaria | Immunogenicity | Midgut | Antibodies | Vectors | Vaccines | Vectors (Biology) | Antibody response
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, p. e67888
The disadvantages of needle-based immunisation motivate the development of simple, low cost, needle-free alternatives. Vaccine delivery to cutaneous... 
ARRAY PATCHES | PRIME-BOOST IMMUNIZATION | IMMUNOGENICITY | POTENT | VIRUS | STABILIZATION | MULTIDISCIPLINARY SCIENCES | MALARIA | PENETRATION | PROTECTIVE EFFICACY | LANGERHANS CELLS | Adenoviruses, Simian - immunology | Genetic Vectors - immunology | Vaccine Potency | Freeze Drying | Vaccines, DNA - immunology | Vaccines, DNA - administration & dosage | Vaccinia virus - genetics | Chemistry, Pharmaceutical | Dermis - immunology | Genetic Vectors - genetics | Vaccinia virus - immunology | Adenoviruses, Simian - genetics | Vaccines, Attenuated - immunology | Animals | Malaria Vaccines - administration & dosage | Epidermis - immunology | Vaccines, Attenuated - administration & dosage | Malaria Vaccines - immunology | Female | T-Lymphocytes - immunology | Mice | Transgenes - immunology | Malaria Vaccines - genetics | Vaccines, Attenuated - genetics | Antigens | Viral proteins | Malaria | Adenoviruses | Skin | Vaccines | T cells | Coatings | Sugars | Transdermal medication | Health care | Bioengineering | Drug delivery systems | Climate | Sucrose | Trehalose | Hot climates | CD8 antigen | Clinical trials | Viruses | Lymphocytes T | Thermal stability | Proteins | Immunology | Lymphocytes | Virions | Low cost | Protective coatings | Vaccinia | Drug dosages | Expression vectors | Vector-borne diseases | Immunization | Disaccharides | Patches (structures) | Cold storage | Vectors (Biology) | Immunogenicity | Antigen-presenting cells | Influenza | Viability | Nanotechnology
Journal Article