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PLoS Computational Biology, ISSN 1553-734X, 03/2017, Volume 13, Issue 3, pp. e1005397 - e1005397
Novel antimalarial therapies are urgently needed for the fight against drug-resistant parasites. The metabolism of malaria parasites in infected cells is an... 
NETWORK ANALYSIS | BIOSYNTHESIS | GROWTH | LIVER | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | MALARIA PARASITE | BLOOD STAGES | SACCHAROMYCES-CEREVISIAE | DRUG TARGETS | CULTURE | FLUX-BALANCE ANALYSIS | Thermodynamics | Metabolic Flux Analysis - methods | Protozoan Proteins - metabolism | Genes, Essential - physiology | Models, Biological | Computer Simulation | Metabolome - physiology | Plasmodium falciparum - physiology | Energy Metabolism - physiology | Nutritional Requirements - physiology | Malaria | Nutrition | Genes | Genomes | Drug resistance | Requirements | Plasmodium falciparum | Metabolites | Analysis | Physiological aspects | Genetic aspects | Models | Energy metabolism | Bioenergetics | Observations | Health aspects | Cell culture | Balances (scales) | Matrices (mathematics) | Genomics | Liver | Erythrocytes | Biochemistry | Systems analysis | Essential nutrients | Data bases | Genetic screening | Drug metabolism | Genetics | Enzymes | Pathogens | Fluctuations | Channeling | Data acquisition | Nucleic acids | Metabolism | Studies | Inhibitors | Computation | Computer applications | Stem cells | Predictions | Death | Health care | Intervention | Drugs | Biotechnology | Animal models | Microbiology | Identification methods | Dihydroorotase | Artemisinin | Risk | Infections | Biosynthesis | Parasites | Nutritional requirements | Databases | Nutrients | Feasibility studies | Data processing | Grants | Antimetabolites | Computer programs | Medicine | Data collection | Position (location) | Index Medicus
Journal Article
Genome Research, ISSN 1088-9051, 05/2004, Volume 14, Issue 5, pp. 917 - 924
Identification of novel targets for the development of more effective antimalarial drugs and vaccines is a primary goal of the Plasmodium genome project.... 
SEQUENCE-ANALYSIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MALARIA VACCINE | DEHYDROGENASE | ERYTHROCYTIC STAGES | IN-VITRO | INHIBITION | DATABASE | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GROWTH | GENETICS & HEREDITY | ANTIMALARIAL ACTIVITY | REDUCTASE | Genes, Essential - drug effects | Plasmodium falciparum - enzymology | Predictive Value of Tests | Genes, Bacterial - genetics | Genes, Protozoan - genetics | Genome, Protozoan | Models, Chemical | Protozoan Proteins - antagonists & inhibitors | Humans | Databases, Genetic | Substrate Specificity - physiology | Escherichia coli Proteins - physiology | Plasmodium falciparum - drug effects | Protozoan Proteins - genetics | Genes, Bacterial - physiology | Protozoan Proteins - metabolism | Plasmodium falciparum - genetics | Escherichia coli - metabolism | Plasmodium falciparum - metabolism | Genomics - methods | Computational Biology - methods | Escherichia coli - enzymology | Enzyme Inhibitors - pharmacology | Escherichia coli Proteins - metabolism | Substrate Specificity - genetics | Protozoan Proteins - physiology | Catalysis - drug effects | Algorithms | Animals | Escherichia coli - genetics | Genes, Essential - physiology | Genes, Protozoan - physiology | Escherichia coli Proteins - genetics | Software | Plasmodium falciparum | Genetic aspects | Research | Malaria | Index Medicus | Resources
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 498, Issue 7455, pp. 502 - 505
Journal Article
Nature, ISSN 0028-0836, 05/2010, Volume 465, Issue 7296, pp. 311 - 315
Journal Article
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 07/2014, Volume 371, Issue 5, pp. 403 - 410
Journal Article
Nature, ISSN 0028-0836, 02/2010, Volume 463, Issue 7281, pp. 632 - 636
During their intraerythrocytic development, malaria parasites export hundreds of proteins to remodel their host cell. Nutrient acquisition, cytoadherence and... 
CALPAIN | FALCIPARUM | MULTIDISCIPLINARY SCIENCES | FOOD VACUOLE | TRAFFICKING | ENDOPLASMIC-RETICULUM | MALARIA PARASITES | VIRULENCE | REVEALS | Plasmodium falciparum - enzymology | Humans | Malaria, Falciparum - pathology | Endoplasmic Reticulum - metabolism | Substrate Specificity | Aspartic Acid Endopeptidases - genetics | Pepstatins - pharmacology | HIV Protease Inhibitors - pharmacology | Malaria, Falciparum - blood | Multiprotein Complexes - metabolism | Protozoan Proteins - metabolism | Genes, Dominant | Biocatalysis - drug effects | Plasmodium falciparum - genetics | Plasmids - genetics | Malaria, Falciparum - metabolism | Erythrocytes - cytology | Plasmodium falciparum - metabolism | Protozoan Proteins - chemistry | Endoplasmic Reticulum - enzymology | Protein Structure, Tertiary | Aspartic Acid Endopeptidases - chemistry | Aspartic Acid Endopeptidases - antagonists & inhibitors | Genes, Essential | Protein Sorting Signals | Amino Acid Motifs | Antimalarials - pharmacology | Protein Transport | Malaria, Falciparum - parasitology | Phenotype | Animals | Aspartic Acid Endopeptidases - metabolism | Erythrocytes - metabolism | Proteomics | Plasmodium falciparum - pathogenicity | Protein Binding | Erythrocytes - parasitology | Plasmodium falciparum | Research | Malaria | Proteases | Erythrocytes | Proteins | Genotype & phenotype | Mass spectrometry | International trade | Enzymes | Protease | Parasites | Endoplasmic reticulum | Exports | Index Medicus
Journal Article
Science, ISSN 0036-8075, 12/2011, Volume 334, Issue 6060, pp. 1283 - 1286
Journal Article