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1. Malaria
: drugs, disease and post-genomic biology
by Sullivan, D. J. 1961- (David Joseph) and Krishna, S. (Sanjeev)
2005, Current topics in microbiology and immunology, ISBN 3540253637, Volume 295, x, 444
Despite rapid increases in knowledge, malaria continues to kill more than a million people each year and causes symptomatic disease in a further 300 million... 
Malaria | Antimalarials | Plasmodium | Medical parasitology | Parasitology | Biomedicine
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2. Full Text Inferring Strain Mixture within Clinical Plasmodium falciparum Isolates from Genomic Sequence Data
by O’Brien, John D and Iqbal, Zamin and Wendler, Jason and Amenga-Etego, Lucas
PLoS Computational Biology, ISSN 1553-734X, 06/2016, Volume 12, Issue 6, p. e1004824
We present a rigorous statistical model that infers the structure of P. falciparum mixtures-including the number of strains present, their proportion within... 
INFECTIONS | HUMAN MALARIA | MULTIPLICITY | MORBIDITY | TANZANIAN CHILDREN | COMPLEXITY | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY | DIVERSITY | SPREAD | CHLOROQUINE RESISTANCE | LIKELIHOOD | Algorithms | Plasmodium falciparum - classification | Species Specificity | Chromosome Mapping - methods | Plasmodium falciparum - genetics | Bayes Theorem | Polymorphism, Single Nucleotide - genetics | DNA, Protozoan - genetics | Sequence Analysis, DNA - methods | Plasmodium falciparum | Genetic aspects | Nucleotide sequencing | Methods | DNA sequencing | Studies | Researchers | Malaria | Laboratories | Funding | Genes | Population | Infections | Genomes | Research | Parasites | Epidemiology
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3. Full Text The Ontology for Biomedical Investigations
by Bandrowski, Anita and Brinkman, Ryan and Brochhausen, Mathias and Brush, Matthew H and Bug, Bill and Chibucos, Marcus C and Clancy, Kevin and Courtot, Mélanie and Derom, Dirk and Dumontier, Michel and Fan, Liju and Fostel, Jennifer and Fragoso, Gilberto and Gibson, Frank and Gonzalez-Beltran, Alejandra and Haendel, Melissa A and He, Yongqun and Heiskanen, Mervi and Hernandez-Boussard, Tina and Jensen, Mark and Lin, Yu and Lister, Allyson L and Lord, Phillip and Malone, James and Manduchi, Elisabetta and McGee, Monnie and Morrison, Norman and Overton, James A and Parkinson, Helen and Peters, Bjoern and Rocca-Serra, Philippe and Ruttenberg, Alan and Sansone, Susanna-Assunta and Scheuermann, Richard H and Schober, Daniel and Smith, Barry and Soldatova, Larisa N and Stoeckert, Christian J and Taylor, Chris F and Torniai, Carlo and Turner, Jessica A and Vita, Randi and Whetzel, Patricia L and Zheng, Jie
PLoS ONE, ISSN 1932-6203, 04/2016, Volume 11, Issue 4, pp. e0154556 - e0154556
The Ontology for Biomedical Investigations (OBI) is an ontology that provides terms with precisely defined meanings to describe all aspects of how... 
DATABASE | TAB | FORMAT | MULTIDISCIPLINARY SCIENCES | MINIMUM INFORMATION | STANDARDS | FRAMEWORK | SPECIFICATION | MICROARRAY DATA | OBO FOUNDRY | FUNCTIONAL GENOMICS | Biological Ontologies - trends | Biological Ontologies - organization & administration | Animals | Semantics | Humans | Computational Biology | Metadata | Software | Biological Ontologies - statistics & numerical data | Internet | Databases, Factual | Application Programming Interface | Usage | Research | Controlled vocabularies | Genomics | Investigations | Ontology | Laboratories | Science | Experiments | Interoperability | Data bases | Consortia | Semantic web | Biomedical materials | Immunology | Bioinformatics | Informatics | Medical research | Data analysis | Knowledge representation | Web Ontology Language-OWL | Knowledge management | Interdisciplinary aspects | Gene expression | Standards | Molecular biology | Index Medicus
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4. Full Text RecQ helicases in the malaria parasite Plasmodium falciparum affect genome stability, gene expression patterns and DNA replication dynamics
by Claessens, Antoine and Harris, Lynne M and Stanojcic, Slavica and Chappell, Lia and Stanton, Adam and Kuk, Nada and Veneziano-Broccia, Pamela and Sterkers, Yvon and Rayner, Julian C and Merrick, Catherine J
PLoS Genetics, ISSN 1553-7390, 07/2018, Volume 14, Issue 7, p. e1007490
The malaria parasite Plasmodium falciparum has evolved an unusual genome structure. The majority of the genome is relatively stable, with mutation rates... 
G4 DNA | RECOMBINATION | CELLS | WRN HELICASE | ANTIGENIC VARIATION | SEQUENCES | RNA-SEQ | HUMAN ERYTHROCYTES | GENETICS & HEREDITY | VIRULENCE GENES | REVEALS | RNA, Protozoan - genetics | Gene Expression Regulation - genetics | RecQ Helicases - metabolism | Humans | RNA, Protozoan - isolation & purification | RecQ Helicases - genetics | Gene Expression Profiling | Plasmodium falciparum - immunology | Protozoan Proteins - genetics | Gene Knockdown Techniques | Whole Genome Sequencing | Malaria, Falciparum - parasitology | Protozoan Proteins - metabolism | Plasmodium falciparum - genetics | Malaria, Falciparum - immunology | DNA Replication - genetics | Antigens, Protozoan - genetics | Genomic Instability - genetics | Evolution, Molecular | Plasmodium falciparum | Microbiological research | DNA replication | Genetic research | Genetic aspects | Research | Gene expression | Helicases | Malaria | Genomics | DNA | Genomes | Genetic transcription | Recombination | Transcription | Laboratories | Entomology | Bias | Erythrocytes | Biology | Mutation rates | Parasites | Kinases | Drug resistance | Replication forks | DNA helicase | Fragile sites | Evolution | Bioinformatics | Supervision | Deoxyribonucleic acid--DNA | Antigens | Parasitology | Diversification | RecQ protein | DNA biosynthesis | Medicine | Mutation | Life Sciences | Microbiology and Parasitology | Populations and Evolution | Biochemistry, Molecular Biology | Genetics | Deoxyribonucleic acid
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5. Full Text Analysis of nuclear and organellar genomes of Plasmodium knowlesi in humans reveals ancient population structure and recent recombination among host-specific subpopulations
by Diez Benavente, Ernest and Florez de Sessions, Paola and Moon, Robert W and Holder, Anthony A and Blackman, Michael J and Roper, Cally and Drakeley, Christopher J and Pain, Arnab and Sutherland, Colin J and Hibberd, Martin L and Campino, Susana and Clark, Taane G
PLoS Genetics, ISSN 1553-7390, 09/2017, Volume 13, Issue 9, p. e1007008
The macaque parasite Plasmodium knowlesi is a significant concern in Malaysia where cases of human infection are increasing. Parasites infecting humans... 
PENINSULAR MALAYSIA | INFECTIONS | TRANSMISSION | PROTEIN | EVOLUTION | GENETICS & HEREDITY | ECOLOGY | HUMAN MALARIA PARASITE | SABAH | ASSOCIATION | VECTORS | Humans | Plasmodium knowlesi - genetics | Macaca fascicularis - genetics | Macaca nemestrina - parasitology | Organelles - genetics | Animals | Insect Vectors - genetics | Macaca fascicularis - parasitology | Host-Pathogen Interactions - genetics | Culicidae - genetics | Malaria - parasitology | Plasmodium knowlesi - pathogenicity | Culicidae - parasitology | Malaria - transmission | Genome | Macaca nemestrina - genetics | Malaria - genetics | Organelles - parasitology | Host-parasite relationships | Plasmodium | Genetic aspects | Genetic recombination | Health aspects | Macaques | Recombination | Parameter estimation | Funding | Infections | Genomes | Dimorphism | Parasites | Epidemiology | Tropical diseases | Proteins | Phylogenetics | Population | Evolution | Genetics | Bioinformatics | Supervision | Genotypes | Deforestation | Medical research | Subpopulations | Mosaics | Malaria | Population structure | Medicine | Councils | Historical structures | Chromosome 8 | Hygiene | Manganese
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6. Full Text Rapid identification of genes controlling virulence and immunity in malaria parasites
by Abkallo, Hussein M and Martinelli, Axel and Inoue, Megumi and Ramaprasad, Abhinay and Xangsayarath, Phonepadith and Gitaka, Jesse and Tang, Jianxia and Yahata, Kazuhide and Zoungrana, Augustin and Mitaka, Hayato and Acharjee, Arita and Datta, Partha P and Hunt, Paul and Carter, Richard and Kaneko, Osamu and Mustonen, Ville and Illingworth, Christopher J. R and Pain, Arnab and Culleton, Richard
PLoS Pathogens, ISSN 1553-7366, 07/2017, Volume 13, Issue 7, p. e1006447
Identifying the genetic determinants of phenotypes that impact disease severity is of fundamental importance for the design of new interventions against... 
LOCALIZATION | PROTEIN | SPECIFICITY | DISULFIDE BONDING STATE | RECEPTOR | MICROBIOLOGY | CHLOROQUINE RESISTANCE | SWISS-MODEL | DETERMINES | VIROLOGY | PLASMODIUM-FALCIPARUM | BINDING | PARASITOLOGY | Humans | Malaria - immunology | Virulence | Merozoite Surface Protein 1 - genetics | Receptors, Cell Surface - metabolism | Plasmodium yoelii - growth & development | Protozoan Proteins - genetics | Immunity | Plasmodium yoelii - genetics | Plasmodium yoelii - metabolism | Merozoite Surface Protein 1 - metabolism | Antigens, Protozoan - metabolism | Plasmodium yoelii - pathogenicity | Protozoan Proteins - metabolism | Malaria - parasitology | Antigens, Protozoan - genetics | Polymorphism, Single Nucleotide | Host-Parasite Interactions | Erythrocytes - parasitology | Malaria - genetics | Receptors, Cell Surface - genetics | Phenotype | Genetic aspects | Virulence (Microbiology) | Malaria | Identification and classification | Science education | Growth rate | Laboratories | Genes | Infections | Genomes | Single-nucleotide polymorphism | Parasites | Gene polymorphism | Blood | Merozoite surface protein 1 | Proteins | Engineering | Immunology | Pain | Parasitic diseases | Bioinformatics | Binding | Vector-borne diseases | Antigens | Blood cells | Zoonoses | Medicine | Pathology | Environmental science | Neural networks | Collaboration | Signal processing | Polymorphism
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7. Full Text Hard inbreeding under extreme environmental conditions is the most important factor of microevolution and speciation
by Stegniy, V N
Russian Journal of Genetics, ISSN 1022-7954, 7/2017, Volume 53, Issue 7, pp. 757 - 765
The ideas on the evolutionary value of hard inbreeding under conditions of extreme environmental conditions (especially temperatures) for the processes of the... 
Human Genetics | hard inbreeding | temperature stress | Biomedicine | Microbial Genetics and Genomics | genome reorganization | genetic polymorphism | Animal Genetics and Genomics | speciation | POLYTENE CHROMOSOMES | DROSOPHILA-MELANOGASTER | TRANSPOSABLE ELEMENTS | POPULATIONS | MOBILE GENETIC ELEMENTS | TRANSPOSITION | MALARIAL MOSQUITOS | P-ELEMENTS | HETEROCHROMATIN | GENETICS & HEREDITY | STRESS | Evolution | Transposons | Environmental quality | Genes | Genomics | Genetic polymorphisms
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8. Full Text malERA: An updated research agenda for basic science and enabling technologies in malaria elimination and eradication
by Wirth, DF and Winzeler, EA and Fenton, B and Adams, JH and Ariey, F and Barillas-Mury, CV and Baum, J and Bhatia, SN and Billker, O and Bopp, SE and Catteruccia, F and Cowman, AF and Chitnis, CE and Crabb, BS and Deitsch, KW and Del Portillo, HA and Djimde, AA and Dobano, C and Duffy, PE and Duraisingh, MT and Happi, C and James, AA and LaMonte, G and Lukens, AK and Llinas, M and Mali, P and Marti, M and Martinez-Barnetche, J and McGovern, V and Mota, MM and Mueller, I and Ndiaye, D and Neafsey, DE and Ntoumi, F and Prachumsri, J and Sharma, P and Shaw, WR and Sinnis, P and Tolia, NH and Volkman, SK and Wenger, EA and Williamson, K and The Malera Refresh Consultative Pa and malERA Refresh Consultative Panel on Basic Science and Enabling Technologies and The malERA Refresh Consultative Panel on Basic Science and Enabling Technologies
PLoS Medicine, ISSN 1549-1277, 11/2017, Volume 14, Issue 11, p. e1002451
Basic science holds enormous power for revealing the biological mechanisms of disease and, in turn, paving the way toward new, effective interventions.... 
IN-VITRO CULTURE | GAMETOCYTE DEVELOPMENT | MEDICINE, GENERAL & INTERNAL | LIVER-STAGE DEVELOPMENT | ARTEMISININ RESISTANCE | GENE DRIVE SYSTEM | RED-BLOOD-CELLS | HIGH-THROUGHPUT ASSAY | EX-VIVO | PLASMODIUM-FALCIPARUM MALARIA | MOSQUITO ANOPHELES-GAMBIAE | Humans | Plasmodium - physiology | Antimalarials - therapeutic use | Plasmodium - drug effects | Disease Eradication - methods | Antimalarials - pharmacology | Malaria - prevention & control | Mosquito Control - methods | Animals | Insect Vectors - physiology | Insect Vectors - drug effects | Malaria - epidemiology | Biomedical Research - methods | Malaria - transmission | Prevention | Disease transmission | Research | Malaria | Disease | Funding | Entomology | Liver | Genes | Science | Insecticides | Infections | Genomes | Biology | Parasites | Proteins | Biomedical materials | Immunology | Life cycle engineering | Vector-borne diseases | Pathogens | CRISPR | Parasitology | Integrated approach | Research & development--R&D | Mosquitoes | Genetic engineering | Open access | Life cycles | Malalties parasitàries | Parasitic diseases | Malària | Research & development | R&D
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9. Full Text PFI1785w: A highly conserved protein associated with pregnancy associated malaria
by Kamaliddin, Claire and Salnot, Virginie and Leduc, Marjorie and Ezinmegnon, Sem and Broussard, Cédric and Fievet, Nadine and Deloron, Philippe and Guillonneau, François and Bertin, Gwladys I
PLoS ONE, ISSN 1932-6203, 11/2017, Volume 12, Issue 11, p. e0187817
Pregnancy-associated malaria (PAM) is one of the severe forms of Plasmodium falciparum infection. The main antigen VAR2CSA is the target of vaccine... 
ANTIBODIES | MULTIDISCIPLINARY SCIENCES | VACCINE | VAR2CSA | PLASMODIUM-FALCIPARUM PARASITES | ERYTHROCYTE | PLACENTAL MALARIA | BINDING | Antigens, Protozoan - chemistry | Peptides - chemistry | Protein Structure, Secondary | Humans | Phylogeography | Peptides - genetics | Plasmodium falciparum - immunology | Pregnancy Complications, Parasitic - metabolism | Malaria Vaccines - chemistry | Antigens, Protozoan - analysis | Pregnancy | Malaria, Falciparum - parasitology | Synthetic Biology | Pregnancy Complications, Parasitic - parasitology | Mass Spectrometry | Proteomics | Malaria, Falciparum - metabolism | Female | Antigens, Protozoan - genetics | Mutation | Complications and side effects | Usage | Immune response | Malaria | Vaccination | Research | Mass spectrometry | Risk factors | Vector-borne diseases | Immunoglobulins | Peptides | Variability | Erythrocytes | Mass spectroscopy | Parasites | Gene expression | Proteins | Studies | Placenta | Womens health | Protein expression | Immune system
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10. Full Text Transcriptomic analysis reveals evidence for a cryptic plastid in the colpodellid Voromonas pontica, a close relative of chromerids and apicomplexan parasites
by Gile, Gillian H and Slamovits, Claudio H
PLoS ONE, ISSN 1932-6203, 05/2014, Volume 9, Issue 5, p. e96258
Colpodellids are free-living, predatory flagellates, but their close relationship to photosynthetic chromerids and plastid-bearing apicomplexan parasites... 
LIFE-CYCLE | HEME-BIOSYNTHESIS PATHWAY | GENOME SEQUENCE | ISOPRENOID BIOSYNTHESIS | MULTIDISCIPLINARY SCIENCES | SUBCELLULAR-LOCALIZATION | METABOLIC MAPS | APICOPLAST | PHYLOGENETIC ANALYSES | EUK-MPLOC | IRON-SULFUR CLUSTERS | Alveolata - physiology | Biological Evolution | Alveolata - ultrastructure | Plastids - ultrastructure | Transcriptome | Plastids - genetics | Gene Expression Profiling | Plastids - physiology | Phylogeny | Alveolata - genetics | Proteins | Phosphates | Sulfur compounds | Cladistic analysis | RNA | Physiological aspects | Amino acids | Photosynthesis | Fourier transforms | Genes | Homology | Biochemistry | Iron | Biosynthesis | Parasites | Gene sequencing | Datasets | Microorganisms | Phylogenetics | Sulfur | Localization | Plastids | Bioinformatics | Cryptosporidium | Enzymes | Integrated software | rRNA | Phosphate transporter | Algae | Metabolism | Ribonucleic acids | Flagellates | Molecular biology | Transporter
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