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Neurobiology of Disease, ISSN 0969-9961, 2008, Volume 33, Issue 2, pp. 193 - 206
Abstract The dysregulation of glycogen synthase kinase-3 (GSK3) has been implicated in Alzheimer disease (AD) pathogenesis and in Aβ-induced neurotoxicity,... 
Neurology | Tau | Neuron damage | c- jun N-terminal kinase | GSK3 | Beta-amyloid | Alzheimer's | c-jun N-terminal kinase | NEUROFIBRILLARY TANGLES | TYROSINE PHOSPHORYLATION | GLYCOGEN-SYNTHASE KINASE-3 | AMYLOID PLAQUES | NEUROSCIENCES | NEUROPSYCHIATRIC SYMPTOMS | IN-VIVO | PRECURSOR PROTEIN | REDUCES TAU PHOSPHORYLATION | TRANSGENIC MICE | COGNITIVE DEFICITS | Phosphorylation | Amyloid beta-Peptides - pharmacology | Caspase 3 - metabolism | Gliosis - chemically induced | Maleimides - adverse effects | tau Proteins - metabolism | JNK Mitogen-Activated Protein Kinases - metabolism | Hippocampus - drug effects | Glycogen - metabolism | Maleimides - therapeutic use | DNA Fragmentation | Neurons - metabolism | Alzheimer Disease - chemically induced | Neurons - drug effects | Disease Models, Animal | Enzyme Inhibitors - adverse effects | Glycogen Synthase Kinase 3 - antagonists & inhibitors | Alzheimer Disease - therapy | Cells, Cultured | Rats | Glycogen Synthase Kinase 3 - metabolism | Enzyme Inhibitors - therapeutic use | Rats, Sprague-Dawley | Animals | Indoles - adverse effects | Maze Learning | Indoles - therapeutic use | Hippocampus - physiology | Nerve Degeneration - drug therapy | Proteolipids | Enzymes | Lipoproteins | Synthesis | Glycogen | Neurons | Analysis | Depression, Mental | GABA | Blood lipoproteins | Saturated fatty acids | Alzheimer's disease | Index Medicus
Journal Article
Ophthalmology, ISSN 0161-6420, 2006, Volume 113, Issue 12, pp. 2221 - 2230
Journal Article
Diabetes Care, ISSN 0149-5992, 11/2005, Volume 28, Issue 11, pp. 2686 - 2690
Journal Article
Immunity, ISSN 1074-7613, 02/2016, Volume 44, Issue 2, pp. 274 - 286
Despite the importance of the co-receptor PD-1 in T cell immunity, the upstream signaling pathway that regulates PD-1 expression has not been defined. Glycogen... 
SIGNAL-TRANSDUCTION | INTERLEUKIN-2 PRODUCTION | CD4 RECEPTOR | PROGRAMMED DEATH-1 | NEGATIVE REGULATION | IN-VIVO | INHIBITORY RECEPTOR PD-1 | PROTEIN-TYROSINE KINASE | IMMUNOLOGY | CHRONIC VIRAL-INFECTION | DISEASE PROGRESSION | Maleimides - administration & dosage | RNA, Small Interfering - genetics | Maleimides - adverse effects | Lymphocytic Choriomeningitis - immunology | Aminophenols - adverse effects | Lymphocytic choriomeningitis virus - physiology | Rhadinovirus - physiology | Cytotoxicity, Immunologic - drug effects | T-Lymphocytes, Cytotoxic - immunology | Cytotoxicity, Immunologic - genetics | Gene Expression Regulation - genetics | T-Lymphocytes, Cytotoxic - virology | Mice, Inbred C57BL | Cells, Cultured | Programmed Cell Death 1 Receptor - metabolism | Glycogen Synthase Kinase 3 - metabolism | Viral Load - genetics | T-Box Domain Proteins - genetics | T-Box Domain Proteins - metabolism | Gene Expression Regulation - drug effects | Animals | Glycogen Synthase Kinase 3 - genetics | CD8-Positive T-Lymphocytes - virology | Mice | Mice, Inbred BALB C | CD8-Positive T-Lymphocytes - immunology | Viral Load - drug effects | Programmed Cell Death 1 Receptor - genetics | Aminophenols - administration & dosage | Herpesviridae Infections - immunology | Peptides | Lymphocytes | Efficiency | Viruses | T cell receptors | Lymphomas | Kinases | Experiments | Viral infections
Journal Article
The International Journal of Neuropsychopharmacology, ISSN 1461-1457, 9/2011, Volume 14, Issue 8, pp. 1051 - 1067
There is a growing body of evidence suggesting that animal models can be developed to probe the specific domains of bipolar disorder (BD) using the... 
bipolar disorder | hyperactivity | mood stabilizers | Antimanic drugs | antipsychotic drugs | PREPULSE INHIBITION | PSYCHIATRY | INDUCED LOCOMOTOR STIMULATION | DOPAMINE TRANSPORTER | NEUROSCIENCES | CLINICAL NEUROLOGY | MOUSE MODEL | DOUBLE-BLIND | STAIRCASE TEST | ANIMAL-MODELS | PHARMACOLOGY & PHARMACY | ACUTE BIPOLAR MANIA | D-AMPHETAMINE | Central Nervous System Stimulants - pharmacology | Antipsychotic Agents - adverse effects | Humans | Maleimides - pharmacology | Motor Activity - drug effects | Male | Thiazoles - therapeutic use | Molecular Targeted Therapy | Dose-Response Relationship, Drug | Thiadiazoles - adverse effects | Maleimides - therapeutic use | Central Nervous System Stimulants - adverse effects | Antipsychotic Agents - therapeutic use | Mice, Mutant Strains | Thiadiazoles - therapeutic use | Urea - analogs & derivatives | Indoles - pharmacology | Drug Therapy, Combination | Antimanic Agents - adverse effects | Disease Models, Animal | Thiadiazoles - pharmacology | Reproducibility of Results | Antimanic Agents - therapeutic use | Antimanic Agents - pharmacology | Glycogen Synthase Kinase 3 - antagonists & inhibitors | Amphetamine - pharmacology | Amphetamine - adverse effects | Glycogen Synthase Kinase 3 - metabolism | Bipolar Disorder - drug therapy | Blood-Brain Barrier - drug effects | Urea - therapeutic use | Animals | Indoles - therapeutic use | Mice | Thiazoles - pharmacology | Antipsychotic Agents - pharmacology | Urea - pharmacology | Psychotropic drugs | Drug therapy | Antidepressants | Rodents
Journal Article
Journal Article
Journal Article
Hepatology, ISSN 0270-9139, 04/2014, Volume 59, Issue 4, pp. 1543 - 1554
This study examines the role of protein kinase C (PKC) and AMP‐activated kinase (AMPK) in acetaminophen (APAP) hepatotoxicity. Treatment of primary mouse... 
OXIDATIVE STRESS | ACTIVATION | INHIBITION | RAT HEPATOCYTES | PHORBOL 12-MYRISTATE 13-ACETATE | AUTOPHAGY | GASTROENTEROLOGY & HEPATOLOGY | ISOENZYMES | INDUCED LIVER-INJURY | EXTENDED FAMILY | CELL-DEATH | Acetaminophen - adverse effects | Mitochondria, Liver - metabolism | Maleimides - pharmacology | Hepatocytes - pathology | Male | Hepatocytes - metabolism | Necrosis - pathology | AMP-Activated Protein Kinases - drug effects | Indoles - pharmacology | Chemical and Drug Induced Liver Injury - pathology | Hepatocytes - drug effects | Disease Models, Animal | JNK Mitogen-Activated Protein Kinases - drug effects | JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors | Protein Kinase C - physiology | AMP-Activated Protein Kinases - antagonists & inhibitors | Mice, Inbred C57BL | Protein Kinase C - drug effects | Cells, Cultured | Necrosis - metabolism | Protein Kinase C - antagonists & inhibitors | Chemical and Drug Induced Liver Injury - physiopathology | Mitochondria, Liver - drug effects | AMP-Activated Protein Kinases - physiology | Animals | Chemical and Drug Induced Liver Injury - metabolism | JNK Mitogen-Activated Protein Kinases - physiology | Signal Transduction - physiology | Mice | Protein Kinase Inhibitors - pharmacology | In Vitro Techniques | Cytotoxicity | Mitochondria | Kinases | Autophagy | Liver | Hepatology | Index Medicus
Journal Article
Anesthesiology, ISSN 0003-3022, 2011, Volume 114, Issue 5, pp. 1048 - 1063
Journal Article
The Journal of Pathology, ISSN 0022-3417, 03/2012, Volume 226, Issue 4, pp. 598 - 608
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 2016, Volume 84, pp. 395 - 402
Journal Article