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The Journal of physiology, ISSN 0022-3751, 07/2010, Volume 588, Issue 14, pp. 2605 - 2619
In vertebrate retina, melatonin regulates various physiological functions. In this work we investigated the mechanisms underlying melatonin‐induced... 
Neurosciences | Physiology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Cyclic GMP - pharmacology | Receptor, Melatonin, MT2 - antagonists & inhibitors | Tetradecanoylphorbol Acetate - pharmacology | Maleimides - pharmacology | Male | Calcium - analysis | Melatonin - physiology | Type C Phospholipases - antagonists & inhibitors | Cyclic GMP-Dependent Protein Kinases - antagonists & inhibitors | Cyclic GMP-Dependent Protein Kinases - physiology | Isoquinolines - pharmacology | Cyclic GMP - analogs & derivatives | Estrenes - pharmacology | Pyrrolidinones - pharmacology | Bridged-Ring Compounds - pharmacology | Egtazic Acid - analogs & derivatives | Indoles - pharmacology | Guanosine Diphosphate - pharmacology | Pertussis Toxin - pharmacology | Retinal Ganglion Cells - physiology | Protein Kinase C - physiology | Retinal Ganglion Cells - enzymology | 8-Bromo Cyclic Adenosine Monophosphate - pharmacology | Rats | Protein Kinase C - antagonists & inhibitors | Receptor, Melatonin, MT2 - physiology | Sulfonamides - pharmacology | Rats, Sprague-Dawley | Animals | Egtazic Acid - pharmacology | Glycine - physiology | Guanosine Diphosphate - analogs & derivatives | Signal Transduction - drug effects | Tetrahydronaphthalenes - pharmacology | Thiones - pharmacology | Carbazoles - pharmacology | Type C Phospholipases - physiology | Melatonin | Phospholipids | Glycine | Ganglion | Gross domestic product | Protein kinases | Kinases | Retina | Index Medicus | Neuroscience
Journal Article
Cardiovascular research, ISSN 0008-6363, 06/2007, Volume 74, Issue 3, pp. 406 - 415
Objectives: Canine atrial cardiomyocytes display a constitutively active, acetylcholine-regulated, time-dependent K current (I ) that contributes to atrial... 
Second-messengers | Signal transduction | Ion-channels | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Maleimides - pharmacology | Adrenergic alpha-Antagonists - pharmacology | Phorbol 12,13-Dibutyrate - pharmacology | Type C Phospholipases - antagonists & inhibitors | Dose-Response Relationship, Drug | Propranolol - pharmacology | Isoquinolines - pharmacology | Phenylephrine - pharmacology | Prazosin - pharmacology | Estrenes - pharmacology | Pyrrolidinones - pharmacology | Clonidine - pharmacology | Indoles - pharmacology | Receptors, Adrenergic, beta-1 - drug effects | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | Action Potentials - drug effects | Acetylcholine - pharmacology | Heart Atria | Receptors, Adrenergic, alpha-1 - drug effects | Bee Venoms - pharmacology | Imidazoles - pharmacology | Protein Kinase C - antagonists & inhibitors | Potassium Channels - drug effects | Sulfonamides - pharmacology | Adrenergic Agents - pharmacology | Piperazines - pharmacology | Clonidine - analogs & derivatives | Patch-Clamp Techniques | Animals | Myocytes, Cardiac - drug effects | Isoproterenol - pharmacology | Dogs | Dihydropyridines - pharmacology | Myocytes, Cardiac - metabolism | Adrenergic alpha-Agonists - pharmacology | Propanolamines - pharmacology | Heart cells | Index Medicus
Journal Article
Journal of Endocrinology, ISSN 0022-0795, 08/2002, Volume 174, Issue 2, pp. 233 - 246
Glucose-dependent insulinotropic polypeptide (GIP) acts as a glucose-dependent growth factor for beta-cells. Here we show that GIP and glucose also act... 
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Apoptosis - drug effects | Calcium - metabolism | Humans | Maleimides - pharmacology | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - analogs & derivatives | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | MAP Kinase Kinase 1 | Isoquinolines - pharmacology | Deoxyglucose - pharmacology | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Indoles - pharmacology | Flavonoids - pharmacology | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | Gastric Inhibitory Polypeptide - pharmacology | B-Lymphocytes - metabolism | Cell Line | Enzyme Inhibitors - pharmacology | Mitogen-Activated Protein Kinase Kinases - antagonists & inhibitors | Arginase - genetics | Protein Kinase C - antagonists & inhibitors | Chelating Agents - pharmacology | Calcium-Calmodulin-Dependent Protein Kinases - antagonists & inhibitors | Sulfonamides - pharmacology | Egtazic Acid - pharmacology | MAP Kinase Signaling System - drug effects | Mitosis - drug effects | Androstadienes - pharmacology | Signal Transduction - drug effects | Glucokinase - antagonists & inhibitors | Plasmids | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - pharmacology | Wortmannin | Genistein - pharmacology | Glucose - metabolism | Alloxan - pharmacology | Benzylamines - pharmacology | Protein-Tyrosine Kinases - antagonists & inhibitors | Index Medicus
Journal Article
Molecules (Basel, Switzerland), ISSN 1420-3049, 2018, Volume 23, Issue 7, p. 1521
Natural products are an important source of pesticide discovery. A series of N-amino-maleimide derivatives containing hydrazone group were designed and... 
Antifungal activity | Methyllinderone | Linderone | Maleimide | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Plant Extracts - chemistry | Nitriles - pharmacology | Lindera - chemistry | Maleimides - pharmacology | Ascomycota - drug effects | Biological Products - pharmacology | Structure-Activity Relationship | Ascomycota - growth & development | Fungicides, Industrial - pharmacology | Microbial Sensitivity Tests | Maleimides - chemical synthesis | Culex - drug effects | Drug Design | Rhizoctonia - growth & development | Flavonoids - pharmacology | Molecular Structure | Carbamates - pharmacology | Biomimetic Materials - chemical synthesis | Pesticides - chemical synthesis | Culex - physiology | Cyclopentanes - pharmacology | Drug Discovery | Biological Products - isolation & purification | Biomimetic Materials - pharmacology | Biological Products - chemistry | Animals | Rhizoctonia - drug effects | Benzimidazoles - pharmacology | Alkenes - pharmacology | Pesticides - pharmacology | Fungicides | Bioassays | Pesticides | Hydrazones | Derivatives | Aquatic insects | Biological activity | Fungi | Synthesis | Fungicidal activity | Natural products | Chlorothalonil | Carbendazim | Phytopathogenic fungi | Index Medicus | maleimide | methyllinderone | antifungal activity | linderone
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 2/2000, Volume 97, Issue 3, pp. 1293 - 1298
Consistent with the epileptogenic and deleterious effects of the potent neurotoxin kainate, the activation of kainate receptors reduces the synaptic inhibition... 
Depolarization | Kainic acid receptors | Brain | Biological Sciences | Receptors | Neuroscience | Interneurons | Low concentrations | Neurons | Pyramidal cells | Agonists | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Propionates - pharmacology | Lidocaine - pharmacology | Receptors, Kainic Acid - classification | Rats, Wistar | Receptors, Presynaptic - physiology | gamma-Aminobutyric Acid - metabolism | 2-Amino-5-phosphonovalerate - pharmacology | Maleimides - pharmacology | Receptors, Kainic Acid - agonists | Virulence Factors, Bordetella - pharmacology | Nerve Tissue Proteins - classification | Pyramidal Cells - physiology | Indoles - pharmacology | Receptors, Presynaptic - classification | Pyramidal Cells - drug effects | Action Potentials - drug effects | Glutamic Acid - drug effects | Nerve Tissue Proteins - physiology | Benzodiazepines - pharmacology | Protein Kinase C - physiology | Glutamic Acid - pharmacology | Signal Transduction | Kainic Acid - pharmacology | Enzyme Inhibitors - pharmacology | Rats | Excitatory Amino Acid Agonists - pharmacology | Excitatory Amino Acid Antagonists - pharmacology | Protein Kinase C - antagonists & inhibitors | Bicuculline - pharmacology | Hippocampus - cytology | Naphthalenes - pharmacology | Isoxazoles - pharmacology | Lidocaine - analogs & derivatives | Patch-Clamp Techniques | Animals | Interneurons - metabolism | alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid - pharmacology | Receptors, Kainic Acid - physiology | Staurosporine - pharmacology | Amino acids | Research | Glutamate | Analysis | Cells | Neurotoxic agents | Neurology | Index Medicus
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 06/2003, Volume 111, Issue 11, pp. 1665 - 1672
  Antimicrobial peptides are effector molecules of the innate immune system and contribute to host defense and regulation of inflammation. The human... 
Index Medicus | Abridged Index Medicus
Journal Article
AJP - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 02/2006, Volume 290, Issue 2, pp. L284 - L290
Journal Article
Clinical and experimental pharmacology & physiology, ISSN 1440-1681, 10/2005, Volume 32, Issue 10, pp. 832 - 838
SUMMARY 1. Cooling has been shown to induce contractions of several smooth muscles in vitro. However, the mechanism involved in the response is not yet known.... 
rat gastric fundus | Rho-kinase | cooling-induced contraction | TRPM8 receptors | cooling‐induced contraction | Rho‐kinase | Cooling-induced contraction | Rat gastric fundus | Pharmacology & Pharmacy | Physiology | Life Sciences & Biomedicine | Science & Technology | Gene Expression - drug effects | Capsaicin - pharmacology | Maleimides - pharmacology | Gastric Fundus - physiology | Male | RNA, Messenger - metabolism | rho-Associated Kinases | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Indoles - pharmacology | Gastric Fundus - metabolism | Protein-Serine-Threonine Kinases - metabolism | Amides - pharmacology | Cold Temperature | Nifedipine - pharmacology | Calcium - pharmacology | Gastric Fundus - drug effects | RNA, Messenger - genetics | Enzyme Inhibitors - pharmacology | Intracellular Signaling Peptides and Proteins | Rats | Capsaicin - analogs & derivatives | Calcium Channel Blockers - pharmacology | Rats, Sprague-Dawley | TRPM Cation Channels - physiology | Animals | TRPM Cation Channels - antagonists & inhibitors | Muscle Contraction - drug effects | Muscle Contraction - physiology | Genistein - pharmacology | TRPM Cation Channels - genetics | Pyridines - pharmacology | Enzyme Activation | In Vitro Techniques | Comparative Study | Cold | Maleimides, pharmacology | Enzyme Inhibitors, pharmacology | Gene Expression, drug effects | In Vitro | TRPM Cation Channels, antagonists and inhibitors | Gastric Fundus, drug effects | Muscle Contraction, drug effects | Calcium Channel Blockers, pharmacology | Genistein, pharmacology | Calcium, pharmacology | Protein-Serine-Threonine Kinases, antagonists and inhibitors | Nifedipine, pharmacology | Pyridines, pharmacology | RNA, Messenger, genetics | Indoles, pharmacology | Capsaicin, analogs and derivatives | Amides, pharmacology | Index Medicus
Journal Article
Journal Article