X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
maleylacetoacetate isomerase (46) 46
humans (27) 27
animals (22) 22
pharmacology & pharmacy (21) 21
glutathione transferase - genetics (20) 20
glutathione transferase - metabolism (19) 19
biochemistry & molecular biology (16) 16
male (14) 14
dichloroacetate (13) 13
glutathione (13) 13
index medicus (13) 13
mice (12) 12
biotransformation (11) 11
dichloroacetic acid (11) 11
tyrosine - metabolism (11) 11
metabolism (10) 10
amino acid sequence (9) 9
gene (9) 9
glutathione transferase (9) 9
glutathione transferase - chemistry (9) 9
molecular sequence data (9) 9
toxicology (9) 9
zeta (9) 9
female (8) 8
identification (8) 8
maleylacetoacetate (8) 8
models, molecular (8) 8
trichloroacetic-acid (8) 8
tyrosine (8) 8
enzymes (7) 7
glutathione transferase zeta (7) 7
hereditary tyrosinemia (7) 7
kinetics (7) 7
s-transferase (7) 7
sequence alignment (7) 7
acetone - analogs & derivatives (6) 6
cis-trans-isomerases - metabolism (6) 6
controlled clinical-trial (6) 6
crystal-structure (6) 6
liver (6) 6
mice, knockout (6) 6
s-transferases (6) 6
acid (5) 5
analysis (5) 5
article (5) 5
base sequence (5) 5
cis-trans-isomerase (5) 5
cis-trans-isomerases - genetics (5) 5
dichloroacetic acid - pharmacology (5) 5
dichloroacetic-acid (5) 5
genes (5) 5
genetics & heredity (5) 5
glutathione - metabolism (5) 5
glutathione s-transferase (5) 5
glutathione transferase - physiology (5) 5
glutathione-s-transferase (5) 5
isoenzymes - genetics (5) 5
mutation (5) 5
oxidative stress (5) 5
pharmacokinetics (5) 5
polymorphism, genetic (5) 5
rats (5) 5
acetone - urine (4) 4
adult (4) 4
b6c3f1 mice (4) 4
binding sites (4) 4
dichloroacetic acid - pharmacokinetics (4) 4
enzyme (4) 4
glutathione transferase - antagonists & inhibitors (4) 4
glutathione transferase - deficiency (4) 4
glutathione transferases (4) 4
inactivation (4) 4
isoenzymes - metabolism (4) 4
isomerization (4) 4
liver - drug effects (4) 4
liver - enzymology (4) 4
maleates - urine (4) 4
pharmacogenetics (4) 4
phylogeny (4) 4
pyruvate-dehydrogenase complex (4) 4
research (4) 4
sequence homology, amino acid (4) 4
substrate specificity (4) 4
trichloroethylene (4) 4
tyrosine catabolism (4) 4
adipogenesis (3) 3
amino acid substitution (3) 3
arabidopsis-thaliana (3) 3
biophysics (3) 3
biotechnology & applied microbiology (3) 3
carnation (3) 3
cell biology (3) 3
chemistry, multidisciplinary (3) 3
coenzyme-a reductase (3) 3
congenital lactic-acidosis (3) 3
crystallography, x-ray (3) 3
cytosol - enzymology (3) 3
dichloroacetic acid - administration & dosage (3) 3
dichloroacetic acid - adverse effects (3) 3
dichloroacetic acid - blood (3) 3
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


DRUG METABOLISM AND DISPOSITION, ISSN 0090-9556, 02/2012, Volume 40, Issue 2, pp. 232 - 239
Glutathione transferase zeta 1 (GSTZ1), also known as maleylacetoacetate isomerase, catalyzes the penultimate step of tyrosine catabolism and metabolizes... 
CONTROLLED CLINICAL-TRIAL | ALPHA-CLASS | INACTIVATION | BIOTRANSFORMATION | METABOLISM | TYROSINE AMINOTRANSFERASE | S-TRANSFERASES | PHARMACOLOGY & PHARMACY | TISSUES | MALEYLACETOACETATE ISOMERASE | DEVELOPMENTAL EXPRESSION
Journal Article
Bioinformation, ISSN 0973-2063, 2017, Volume 13, Issue 5, pp. 140 - 143
Tyrosinemia type I is the result of genetic disorder in fomaryl acetoacetase gene that leads to 4-fumaryl acetoacetate accumulation. The current treatment for... 
Journal Article
Journal Article
Journal Article
The Journal of Clinical Pharmacology, ISSN 0091-2700, 01/2015, Volume 55, Issue 1, pp. 50 - 55
Dichloroacetate (DCA) is biotransformed by glutathione transferase zeta 1 (GSTZ1), a bifunctional enzyme that, as maleylacetoacetate isomerase (MAAI),... 
congenital lactic acidosis | dichloroacetate | glutathione transferase zeta 1 | maleylacetoacetate isomerase | pharmacokinetics | tyrosine | pharmacogenetics | mitochondrial disease | Dichloroacetate | Tyrosine | Glutathione transferase zeta 1 | Maleylacetoacetate isomerase | Pharmacogenetics | Congenital lactic acidosis | Pharmacokinetics | Mitochondrial disease | CONTROLLED CLINICAL-TRIAL | CONGENITAL LACTIC-ACIDOSIS | PHARMACOLOGY & PHARMACY | PYRUVATE-DEHYDROGENASE COMPLEX | Haplotypes | Humans | Genetic Diseases, Inborn - genetics | Mitochondrial Diseases - metabolism | Child, Preschool | Infant | Male | Dichloroacetic Acid - blood | Young Adult | Glutathione Transferase - genetics | Maleates - urine | Dichloroacetic Acid - urine | Adult | Female | Genetic Diseases, Inborn - metabolism | Child | Mitochondrial Diseases - genetics | Mitochondrial Diseases - drug therapy | Acetone - analogs & derivatives | Double-Blind Method | Acetone - urine | Tyrosine - metabolism | Dichloroacetic Acid - pharmacokinetics | Adolescent | Polymorphism, Single Nucleotide | Kinetics | Aminolevulinic Acid - urine | Genetic Diseases, Inborn - drug therapy | Ivacaftor | Usage | Warfarin | Analysis | Cytochromes | Glycoproteins | Health aspects | Enzymes | Plasma | Index Medicus | Maleylacetoacetate Isomerase | Mitochondrial Disease | Glutathione Transferase Zeta 1 | Congenital Lactic Acidosis
Journal Article
The Journal of Clinical Pharmacology, ISSN 0091-2700, 6/2012, Volume 52, Issue 6, pp. 837 - 849
Journal Article
Molecular Physics, ISSN 0026-8976, 04/2012, Volume 110, Issue 8, pp. 467 - 482
DFT at B3LYP/6-31G (d,p) level calculation results for the amine-catalysed isomerization of dimethyl maleate revealed that the mechanism proceeds via four... 
isomerization of dimethyl maleate | dimethyl fumarate | dimethyl maleate | amine-catalysed cis-trans isomerization | DFT calculations | FUMARIC-ACID ESTERS | DENSITY | DESIGN | PRODRUGS | MALEYLACETOACETATE | SOLUTES | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | Studies | Dimethyl | Maleates | Amines | Catalysts | Mathematical analysis | Isomerization | Activation energy | Bonding
Journal Article