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Journal of mammary gland biology and neoplasia, ISSN 0183-3021, 1996
Journal
PLoS biology, ISSN 1544-9173, 2014, Volume 12, Issue 9, pp. e1001945 - e1001945
Malignant carcinomas that recur following therapy are typically de-differentiated and multidrug resistant (MDR). De-differentiated cancer cells acquire MDR by... 
Biochemistry & Molecular Biology | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Phosphorylation | eIF-2 Kinase - metabolism | Humans | Gene Expression Regulation, Neoplastic | Neoplasm Recurrence, Local - drug therapy | Gene Expression Profiling | Mammary Neoplasms, Experimental - metabolism | Mammary Neoplasms, Experimental - genetics | Breast Neoplasms - metabolism | Neoplasm Recurrence, Local - pathology | Neoplasm Grading | Mammary Neoplasms, Experimental - pathology | Female | NF-E2-Related Factor 2 - genetics | Transcription, Genetic | Antineoplastic Agents - pharmacology | Carcinoma - pathology | Mammary Neoplasms, Experimental - drug therapy | eIF-2 Kinase - genetics | Carcinoma - drug therapy | Neoplasm Recurrence, Local - metabolism | Oxidation-Reduction | Signal Transduction | Mammary Glands, Animal - pathology | Mammary Glands, Animal - drug effects | Mice, SCID | Breast Neoplasms - drug therapy | Drug Resistance, Neoplasm - genetics | Animals | Breast Neoplasms - genetics | Mammary Glands, Animal - metabolism | Breast Neoplasms - pathology | NF-E2-Related Factor 2 - metabolism | Cell Line, Tumor | Carcinoma - genetics | Mice, Inbred NOD | Neoplasm Recurrence, Local - genetics | Carcinoma - metabolism | Cell Dedifferentiation - genetics | Cell research | Oncology, Experimental | Cancer cells | Cellular signal transduction | Research | Drug resistance | Cell differentiation | Health aspects | Cancer | Index Medicus | Medical research | Enzymes | Transcription factors | Biomedical research | Breast cancer | Kinases | Gene expression | Experiments | Cancer therapies | Antioxidants | Medical prognosis | Data collection | Tumors
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 01/2015, Volume 125, Issue 2, pp. 621 - 635
The gene encoding F-box protein FBXW7 is frequently mutated in many human cancers. Although most previous studies have focused on the tumor-suppressive... 
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | F-Box-WD Repeat-Containing Protein 7 | Receptors, Notch - metabolism | Stromal Cells - pathology | Humans | Gene Expression Regulation, Neoplastic | Receptors, Notch - genetics | CD2 Antigens - genetics | Mammary Neoplasms, Experimental - metabolism | Mammary Neoplasms, Experimental - genetics | Breast Neoplasms - metabolism | Breast Neoplasms - therapy | Neoplasm Metastasis | Mammary Neoplasms, Experimental - pathology | Cell Cycle Proteins - genetics | Female | CD2 Antigens - metabolism | Chemokine CCL2 - metabolism | Retrospective Studies | Neoplasm Proteins - genetics | Macrophages - pathology | Neoplasm Proteins - biosynthesis | Stromal Cells - metabolism | F-Box Proteins - biosynthesis | Chemokine CCL2 - genetics | Mice, Transgenic | Cell Cycle Proteins - biosynthesis | Ubiquitin-Protein Ligases - biosynthesis | Mammary Neoplasms, Experimental - therapy | Macrophages - metabolism | Animals | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Cell Line, Tumor | Mice | Ubiquitin-Protein Ligases - genetics | F-Box Proteins - genetics | Development and progression | Genetic aspects | Metastasis | Carrier proteins | Health aspects | Cellular control mechanisms | Proteins | Statistical analysis | Genes | Rodents | Melanoma | Breast cancer | Tumorigenesis | Mutation | Chemokines | Tumors | Recruitment | Index Medicus | Abridged Index Medicus
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 05/2013, Volume 110, Issue 24, pp. 9920 - 9925
The ten-eleven translocation (TET) family of methylcytosine dioxygenases initiates demethylation of DNA and is associated with tumorigenesis in many cancers;... 
Genes | DNA | Cell lines | Breast cancer | Breast neoplasms | Gene expression regulation | Promoter regions | Metastasis | Embryonic stem cells | Tumors | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Wnt1 Protein - genetics | Prognosis | Oligonucleotide Array Sequence Analysis | Homeodomain Proteins - metabolism | Humans | Immunoblotting | Male | Transplantation, Heterologous | Gene Expression Profiling | Wnt1 Protein - metabolism | Mammary Neoplasms, Experimental - metabolism | Mammary Neoplasms, Experimental - genetics | Breast Neoplasms - metabolism | DNA-Binding Proteins - metabolism | Mixed Function Oxygenases | Neoplasm Metastasis | HMGA2 Protein - metabolism | RNA Interference | HMGA2 Protein - genetics | Mammary Neoplasms, Experimental - pathology | Female | Proto-Oncogene Proteins - metabolism | Mice, Inbred C57BL | Kaplan-Meier Estimate | Mice, Transgenic | Proto-Oncogene Proteins - genetics | Signal Transduction - genetics | DNA-Binding Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Homeodomain Proteins - genetics | Mice, Knockout | Animals | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Cell Line, Tumor | Mice | Genetic aspects | Research | Translocation (Genetics) | Genetic regulation | Index Medicus | Biological Sciences
Journal Article
The Journal of Immunology, ISSN 0022-1767, 02/2002, Volume 168, Issue 3, pp. 1356 - 1361
.... TRAIL gene-targeted mice were more susceptible to experimental and spontaneous tumor metastasis, and the immunotherapeutic value of alpha-galactosylceramide was diminished in TRAIL gene-targeted mice... 
Life Sciences & Biomedicine | Immunology | Science & Technology | Mammary Neoplasms, Experimental - immunology | Neoplasm Transplantation | Kidney Neoplasms - genetics | Membrane Glycoproteins - biosynthesis | Tumor Necrosis Factor-alpha - genetics | Kidney Neoplasms - immunology | Tumor Cells, Cultured - transplantation | Fibrosarcoma - immunology | Fibrosarcoma - chemically induced | Tumor Necrosis Factor-alpha - deficiency | Mammary Neoplasms, Experimental - genetics | Membrane Glycoproteins - physiology | Fibrosarcoma - pathology | TNF-Related Apoptosis-Inducing Ligand | Disease Susceptibility - immunology | Neoplasm Metastasis - immunology | Cell Division - immunology | Cell Transformation, Neoplastic - genetics | Mammary Neoplasms, Experimental - pathology | Killer Cells, Natural - immunology | Female | Adenocarcinoma - genetics | Liver Neoplasms - secondary | Cell Division - genetics | Liver Neoplasms - prevention & control | Cytotoxicity, Immunologic - genetics | Gene Targeting | Mammary Neoplasms, Experimental - prevention & control | Genetic Predisposition to Disease | Liver Neoplasms - genetics | Adenocarcinoma - immunology | Mice, Inbred C57BL | Liver Neoplasms - immunology | Methylcholanthrene - toxicity | Adenocarcinoma - secondary | Membrane Glycoproteins - genetics | Mice, Knockout | Neoplasm Metastasis - genetics | Cell Transformation, Neoplastic - immunology | Fibrosarcoma - genetics | Animals | Apoptosis Regulatory Proteins | Tumor Necrosis Factor-alpha - physiology | Ligands | Mice | Mice, Inbred BALB C | Tumor Necrosis Factor-alpha - biosynthesis | Membrane Glycoproteins - deficiency | TRAIL protein | Index Medicus | Abridged Index Medicus
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 01/2008, Volume 118, Issue 1, pp. 64 - 78
overexpression of the receptor tyrosine kinase EPH receptor A2 (EphA2) is commonly observed in aggressive breast cancer and correlates with a poor prognosis.... 
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Adenocarcinoma - pathology | Cell Proliferation | Receptor, ErbB-2 - genetics | Humans | Receptor, EphA2 - metabolism | Receptor, ErbB-2 - metabolism | Male | Mammary Glands, Human - metabolism | Mammary Neoplasms, Experimental - metabolism | Cell Movement - genetics | Mammary Neoplasms, Experimental - genetics | Breast Neoplasms - metabolism | Breast Neoplasms - therapy | Neoplasm Metastasis | Adenocarcinoma - metabolism | MAP Kinase Signaling System - genetics | Cell Transformation, Neoplastic - genetics | Mammary Neoplasms, Experimental - pathology | Female | Adenocarcinoma - genetics | Antigens, Polyomavirus Transforming - genetics | Antigens, Polyomavirus Transforming - metabolism | Mammary Glands, Animal - pathology | rho GTP-Binding Proteins - genetics | Mammary Glands, Human - pathology | Mice, Transgenic | Cell Transformation, Neoplastic - metabolism | Mammary Neoplasms, Experimental - therapy | Animals | Breast Neoplasms - genetics | Adenocarcinoma - therapy | Mammary Glands, Animal - metabolism | Breast Neoplasms - pathology | rho GTP-Binding Proteins - metabolism | Receptor, EphA2 - genetics | Mice | Cell Transformation, Neoplastic - pathology | Adenocarcinoma | Polymerase chain reaction | Cell receptors | Genetic aspects | Research | Health aspects | Risk factors | Index Medicus | Abridged Index Medicus
Journal Article
Nature (London), ISSN 1476-4687, 11/2015, Volume 527, Issue 7579, pp. 472 - 476
Journal Article
The Journal of immunology (1950), ISSN 1550-6606, 12/2000, Volume 165, Issue 11, pp. 6015 - 6019
STAT4 and STAT6 are essential for the development of CD4(+) Th1 and Th2 development, respectively, Tumor immunologists have hypothesized that Th1 cells are... 
Life Sciences & Biomedicine | Immunology | Science & Technology | Mammary Neoplasms, Experimental - immunology | Bone Marrow Neoplasms - immunology | Bone Marrow Neoplasms - genetics | Mammary Neoplasms, Experimental - genetics | STAT6 Transcription Factor | T-Lymphocytes, Cytotoxic - pathology | CD4-Positive T-Lymphocytes - immunology | Cell Differentiation - genetics | Brain Neoplasms - secondary | Brain Neoplasms - immunology | Lung Neoplasms - secondary | Neoplasm Metastasis - immunology | Cell Division - immunology | Neoplasm Metastasis - prevention & control | Mammary Neoplasms, Experimental - pathology | Trans-Activators - genetics | Liver Neoplasms - secondary | Cell Division - genetics | Liver Neoplasms - prevention & control | Lung Neoplasms - genetics | Bone Marrow Neoplasms - prevention & control | Cytotoxicity, Immunologic - genetics | Mammary Neoplasms, Experimental - prevention & control | Liver Neoplasms - genetics | Brain Neoplasms - genetics | Liver Neoplasms - immunology | Lymphatic Metastasis | Bone Marrow Neoplasms - secondary | Disease Progression | Mice, Knockout | Brain Neoplasms - prevention & control | Cell Differentiation - immunology | Neoplasm Metastasis - genetics | Lung Neoplasms - immunology | Animals | Trans-Activators - deficiency | Lung Neoplasms - prevention & control | Neoplasm Metastasis - pathology | Mice | Mice, Inbred BALB C | CD8-Positive T-Lymphocytes - immunology | Index Medicus | Abridged Index Medicus
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 06/2013, Volume 110, Issue 27, pp. 11091 - 11096
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 11/2014, Volume 111, Issue 46, pp. 16532 - 16537
We have developed a screening platform for the isolation of genetic entities involved in metastatic reactivation... 
Dormancy | MicroRNA | Lungs | Libraries | Metastasis | Lesions | Genetic screening | Cells | Tumors | Cancer | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Neoplasm Transplantation | RNA, Small Interfering - genetics | Proviruses - isolation & purification | Genes, Neoplasm | Neoplasm Proteins - physiology | DNA, Complementary - genetics | Gene Expression Regulation, Neoplastic | RNA, Neoplasm - isolation & purification | MicroRNAs - isolation & purification | Lung Neoplasms - secondary | Proviruses - genetics | Retroviridae - genetics | Mammary Neoplasms, Experimental - pathology | Female | Neoplasm Proteins - genetics | Carcinoma - secondary | High-Throughput Screening Assays - methods | Transduction, Genetic | Gene Library | Retroviridae - isolation & purification | Virus Integration | Genetic Vectors - genetics | Genetic Vectors - isolation & purification | Neoplasm Metastasis - genetics | Animals | Neoplasm Metastasis - pathology | Cell Line, Tumor | RNA, Neoplasm - genetics | Mice | Mice, Inbred BALB C | MicroRNAs - genetics | DNA, Neoplasm - genetics | Oncology, Experimental | Genetic research | Genetic aspects | Research | Nucleotide sequencing | Methods | DNA sequencing | Index Medicus | forward genetic screens | Biological Sciences | cDNA library screen | microRNA library screen | shRNA library screen | metastatic reactivation
Journal Article