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Science Translational Medicine, ISSN 1946-6234, 03/2011, Volume 3, Issue 73, pp. 73ra21 - 73ra21
Journal Article
Cancer Discovery, ISSN 2159-8274, 06/2011, Volume 1, Issue 1, pp. 54 - 67
Immune-regulated pathways influence multiple aspects of cancer development. In this article we demonstrate that both macrophage abundance and T-cell abundance... 
CELL LUNG-CANCER | MAMMARY-TUMORS | COLONY-STIMULATING FACTOR | ONCOLOGY | ANGIOGENIC SWITCH | MOUSE MODEL | RECEPTOR EXPRESSION | TUMOR-ASSOCIATED MACROPHAGES | SUPPRESSOR-CELLS | MYELOID CELLS | ENDOTHELIAL GROWTH-FACTOR | Mammary Neoplasms, Experimental - immunology | Lung Neoplasms - drug therapy | Receptor, Macrophage Colony-Stimulating Factor - immunology | Epithelial Cells - metabolism | Paclitaxel - pharmacology | Prognosis | Follow-Up Studies | Breast Neoplasms - immunology | Epithelial Cells - drug effects | Humans | Lung Neoplasms - metabolism | Mammary Neoplasms, Experimental - metabolism | Receptor, Macrophage Colony-Stimulating Factor - metabolism | Breast Neoplasms - metabolism | Leukocytes - immunology | Signal Transduction - immunology | Neoplasm Metastasis | Lung Neoplasms - secondary | CD8-Positive T-Lymphocytes - metabolism | Female | Macrophages - immunology | Mammary Neoplasms, Experimental - drug therapy | Survival Rate | Macrophage Colony-Stimulating Factor - metabolism | Breast Neoplasms - drug therapy | Macrophage Colony-Stimulating Factor - immunology | Tumor Microenvironment - immunology | Disease-Free Survival | Lung Neoplasms - immunology | Macrophages - metabolism | Animals | Signal Transduction - drug effects | CD8-Positive T-Lymphocytes - drug effects | Epithelial Cells - immunology | Leukocytes - drug effects | Macrophages - drug effects | Aged | Mice | CD8-Positive T-Lymphocytes - immunology | Leukocytes - metabolism | Cohort Studies | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 05/2011, Volume 71, Issue 9, pp. 3364 - 3376
Journal Article
Cell, ISSN 0092-8674, 10/2013, Volume 155, Issue 2, pp. 397 - 409
Journal Article
Cancer Research, ISSN 0008-5472, 06/2014, Volume 74, Issue 11, pp. 2962 - 2973
Journal Article
Cell, ISSN 0092-8674, 2004, Volume 117, Issue 7, pp. 927 - 939
Journal Article
BBA - Molecular Cell Research, ISSN 0167-4889, 07/2014, Volume 1843, Issue 7, pp. 1414 - 1426
The oncofetal H19 gene transcribes a long non-coding RNA(lncRNA) that is essential for tumor growth. Here we found that numerous established inducers of... 
Epithelial to mesenchymal transition | H19 | miR-675 | Positive loop | Slug | E-cadherin | MiR-675 | ACTIVATION | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | CANCER | EMT | CELL BIOLOGY | EPITHELIAL-MESENCHYMAL TRANSITION | NONCODING RNA | CROSS-TALK | GENE | RESISTANCE | Oxygen - pharmacology | Cadherins - metabolism | Drug Resistance, Multiple | Humans | Gene Expression Regulation, Neoplastic | MicroRNAs - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Epithelial-Mesenchymal Transition - genetics | Mammary Neoplasms, Experimental - metabolism | Mammary Neoplasms, Experimental - genetics | Oxygen - metabolism | Proto-Oncogene Proteins c-akt - genetics | Breast Neoplasms - metabolism | Cell Hypoxia | Neoplasm Metastasis | Mammary Neoplasms, Experimental - pathology | Female | Cadherins - genetics | Proto-Oncogene Proteins c-akt - metabolism | Snail Family Transcription Factors | Signal Transduction | Mammary Glands, Animal - pathology | RNA, Long Noncoding - genetics | Transcription Factors - genetics | Phosphatidylinositol 3-Kinases - genetics | Transcription Factors - metabolism | Transforming Growth Factor beta - pharmacology | Drug Resistance, Neoplasm - genetics | Feedback, Physiological | Animals | Breast Neoplasms - genetics | Mammary Glands, Animal - metabolism | Breast Neoplasms - pathology | Cell Line, Tumor | Mice | MicroRNAs - genetics | RNA, Long Noncoding - metabolism | Development and progression | Metastasis | RNA | Transforming growth factors | Analysis
Journal Article
International Journal of Cancer, ISSN 0020-7136, 04/2014, Volume 134, Issue 7, pp. 1669 - 1682
The role of IL‐33/ST2 pathway in antitumor immunity is unclear. Using 4T1 breast cancer model we demonstrate time‐dependent increase of endogenous IL‐33 at... 
IL‐33 | NK cells | dendritic cells | T regs | myeloid‐derived suppressor cells | innate lymphoid cells | 4T1 mammary carcinoma | IL-33 | myeloid-derived suppressor cells | TUMOR | ST2 | MYELOID SUPPRESSOR-CELLS | PROGNOSTIC-FACTOR | ONCOLOGY | INFLAMMATION | CYTOKINE IL-33 | EXPRESSION | T-CELLS | Interleukin-1 Receptor-Like 1 Protein | Mammary Neoplasms, Experimental - immunology | Cell Growth Processes - immunology | Spleen - immunology | Breast Neoplasms - immunology | Immunity, Innate - genetics | Killer Cells, Natural - pathology | Mammary Neoplasms, Experimental - metabolism | Interleukins - metabolism | Mammary Neoplasms, Experimental - genetics | Breast Neoplasms - metabolism | T-Lymphocytes, Cytotoxic - pathology | Receptors, Interleukin - metabolism | Interleukins - genetics | Neoplasm Metastasis | Lymphocytes - immunology | Interleukins - immunology | Mammary Neoplasms, Experimental - pathology | CD8-Positive T-Lymphocytes - metabolism | Killer Cells, Natural - immunology | Female | Cell Growth Processes - genetics | Spleen - pathology | Lymphocytes - metabolism | T-Lymphocytes, Cytotoxic - immunology | Receptors, Interleukin - immunology | Interleukin-33 | Receptors, Interleukin - genetics | Disease Progression | Immunity, Innate - immunology | Lymphocytes - pathology | Animals | Breast Neoplasms - genetics | Spleen - metabolism | T-Lymphocytes, Cytotoxic - metabolism | Breast Neoplasms - pathology | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Killer Cells, Natural - metabolism | CD8-Positive T-Lymphocytes - immunology | Phosphates | RNA | Dendritic cells | Growth | Development and progression | Breast cancer | Metastasis | Transforming growth factors | T cells | Interleukins | Analysis | Bone morphogenetic proteins | Neovascularization | Cytokines | Rodents | Immunotherapy | Immune system | Tumors | Index Medicus
Journal Article
Science, ISSN 0036-8075, 1/2012, Volume 335, Issue 6066, pp. 348 - 353
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2013, Volume 110, Issue 24, pp. 9920 - 9925
The ten-eleven translocation (TET) family of methylcytosine dioxygenases initiates demethylation of DNA and is associated with tumorigenesis in many cancers;... 
Genes | DNA | Cell lines | Breast cancer | Breast neoplasms | Gene expression regulation | Promoter regions | Metastasis | Embryonic stem cells | Tumors | MAMMALIAN DNA | 5-METHYLCYTOSINE | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | MOUSE | TISSUE | GENE-EXPRESSION | 5-HYDROXYMETHYLCYTOSINE | ACTIVE DNA DEMETHYLATION | TET PROTEINS | MLL | Wnt1 Protein - genetics | Prognosis | Oligonucleotide Array Sequence Analysis | Homeodomain Proteins - metabolism | Humans | Immunoblotting | Male | Transplantation, Heterologous | Gene Expression Profiling | Wnt1 Protein - metabolism | Mammary Neoplasms, Experimental - metabolism | Mammary Neoplasms, Experimental - genetics | Breast Neoplasms - metabolism | DNA-Binding Proteins - metabolism | Mixed Function Oxygenases | Neoplasm Metastasis | HMGA2 Protein - metabolism | RNA Interference | HMGA2 Protein - genetics | Mammary Neoplasms, Experimental - pathology | Female | Proto-Oncogene Proteins - metabolism | Mice, Inbred C57BL | Kaplan-Meier Estimate | Mice, Transgenic | Proto-Oncogene Proteins - genetics | Signal Transduction - genetics | DNA-Binding Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Homeodomain Proteins - genetics | Mice, Knockout | Animals | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Cell Line, Tumor | Mice | Genetic aspects | Research | Translocation (Genetics) | Genetic regulation | Genetic engineering | Rodents | Binding sites | Index Medicus | Biological Sciences
Journal Article