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Science, ISSN 0036-8075, 1/2012, Volume 335, Issue 6066, pp. 348 - 353
Journal Article
Molecular Cancer Therapeutics, ISSN 1535-7163, 03/2009, Volume 8, Issue 3, pp. 490 - 498
Journal Article
Nature communications, ISSN 2041-1723, 2016, Volume 7, Issue 1, p. 11838
Journal Article
Breast Cancer Research, ISSN 1465-5411, 08/2011, Volume 13, Issue 4, pp. R78 - R78
Journal Article
Breast Cancer Research, ISSN 1465-5411, 10/2013, Volume 15, Issue 5, pp. R100 - R100
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2012, Volume 7, Issue 12, p. e52175
PG545 is a clinically relevant heparan sulfate (HS) mimetic which, in addition to possessing anti-angiogenic properties, also acts as a heparanase inhibitor... 
TARGET | ANTIANGIOGENIC THERAPY | LUNG-CANCER | IMPACT | ANGIOGENESIS | CANCER METASTASIS | MULTIDISCIPLINARY SCIENCES | TUMOR | INHIBITOR | ENDOTHELIAL GROWTH-FACTOR | DISEASE PROGRESSION | Niacinamide - analogs & derivatives | Lung Neoplasms - drug therapy | Lung Neoplasms - mortality | Humans | Glucuronidase - metabolism | Immunoenzyme Techniques | Lung Neoplasms - secondary | Mammary Neoplasms, Experimental - pathology | Female | Glucuronidase - antagonists & inhibitors | Neovascularization, Pathologic - prevention & control | Antineoplastic Agents - pharmacology | Mammary Neoplasms, Experimental - drug therapy | Mammary Neoplasms, Experimental - mortality | Human Umbilical Vein Endothelial Cells - drug effects | Enzyme-Linked Immunosorbent Assay | Cells, Cultured | Angiogenesis Inhibitors - pharmacology | Antineoplastic Combined Chemotherapy Protocols | Disease Progression | Animals | Mice | Phenylurea Compounds - pharmacology | Niacinamide - pharmacology | Saponins - pharmacology | Enzymes | Carcinoma | Patient outcomes | Analysis | Respiratory agents | Breast cancer | Metastasis | Sulfates | Cancer | Animal models | Lung cancer | Kinases | Cancer therapies | Metastases | Angiogenesis | Signal transduction | Breast carcinoma | Surgery | Extracellular matrix | Inhibition | Vascular endothelial growth factor | Protein-tyrosine kinase | Tyrosine | Heparan sulfate | Medical research | Research & development--R&D | Tumor cells | Survival | Signaling | Inhibitors | Medical prognosis | Sulfate | Angiogenesis inhibitors | Pharmaceuticals | Tumors | Research & development | R&D
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, p. e80305
Despite paclitxael's clinical success, treating hormone-refractory breast cancer remains challenging. Paclitaxel has a poor pharmacological profile,... 
Mammary Neoplasms, Experimental - immunology | Lung Neoplasms - drug therapy | Peripheral Nervous System Diseases - chemically induced | Mammary Glands, Animal | Breast Neoplasms - immunology | Lung Neoplasms - mortality | Humans | Transplantation, Heterologous | Hyperalgesia - pathology | Drug Dosage Calculations | Lung Neoplasms - secondary | Estrenes - pharmacology | Mammary Neoplasms, Experimental - pathology | Female | Antineoplastic Agents - pharmacology | Peripheral Nervous System Diseases - pathology | Peripheral Nervous System Diseases - immunology | Mammary Neoplasms, Experimental - drug therapy | Mammary Neoplasms, Experimental - mortality | Antigens, Polyomavirus Transforming - genetics | Drug Administration Schedule | Adenocarcinoma - immunology | Paclitaxel - adverse effects | Rats | Mice, Transgenic | Adenocarcinoma - drug therapy | Adenocarcinoma - secondary | Disease Progression | Hyperalgesia - immunology | Lung Neoplasms - immunology | Animals | Antigens, Polyomavirus Transforming - immunology | Hyperalgesia - drug therapy | Breast Neoplasms - pathology | Survival Analysis | Mice | Peripheral Nervous System Diseases - drug therapy | Adenocarcinoma - mortality | Antigens | Breast cancer | Genetic engineering | Metastasis | Health aspects | Paclitaxel | Drugs | Animal models | Toxicity | Clinical trials | Oncology | Peripheral neuropathy | Cancer therapies | Metastases | Anticancer properties | Neurotoxicity | Transgenic animals | Rodents | Cell cycle | Xenografts | Inhibition | Neutropenia | Pain perception | Transgenic mice | Pharmacology | Survival | Lungs | Womens health | Breast | In vivo methods and tests | Tumors | Cancer | Apoptosis
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, p. e85398
TGF beta is reportedly responsible for accumulation of CD4(+)Foxp3(+) regulatory T cells (Tregs) in tumor. Thus, we treated mouse 4T1 mammary carcinoma with... 
GROWTH-FACTOR-BETA | IMMUNE CELLS | METASTASIS | IMMUNOSUPPRESSION | MULTIDISCIPLINARY SCIENCES | PROSTATE-CANCER | REGULATORY T-CELLS | TUMOR-SUPPRESSOR | SUPPRESSOR-CELLS | MYELOID CELLS | EXPRESSION | Forkhead Transcription Factors - immunology | Mammary Neoplasms, Experimental - immunology | B7-1 Antigen - genetics | Humans | Carcinoma - mortality | Antineoplastic Agents, Alkylating - pharmacology | T-Lymphocytes, Regulatory - pathology | Mammary Glands, Animal - immunology | T-Lymphocytes, Regulatory - immunology | CD11b Antigen - genetics | Immunotherapy | Gene Expression - immunology | Mammary Neoplasms, Experimental - pathology | Transforming Growth Factor beta - antagonists & inhibitors | Female | Interferon-gamma - genetics | Carcinoma - pathology | Drug Therapy, Combination | Transforming Growth Factor beta - immunology | Mammary Neoplasms, Experimental - mortality | CD11b Antigen - immunology | B7-1 Antigen - immunology | Carcinoma - immunology | Mammary Glands, Animal - pathology | Antibodies, Neutralizing - pharmacology | Mammary Glands, Animal - drug effects | Forkhead Transcription Factors - genetics | Mammary Neoplasms, Experimental - therapy | Drug Synergism | T-Lymphocytes, Regulatory - drug effects | Animals | Cyclophosphamide - pharmacology | Interferon-gamma - immunology | Survival Analysis | Cell Line, Tumor | Lymphocyte Count | Carcinoma - therapy | Mice | Carcinoma | Cytotoxicity | Lymphocytes T | Metastasis | Metastases | Anticancer properties | Immunology | Lymphocytes | Foxp3 protein | Inhibition | Mammary gland | Growth factors | Immune system | Spleen | Medical research | Antigens | CD11b antigen | Dendritic cells | Immunoregulation | CD80 antigen | Breast cancer | Survival | CD4 antigen | Cyclophosphamide | Major histocompatibility complex | Lungs | γ-Interferon | Infiltration | Laboratory animals | Prostate cancer | Tumors
Journal Article
Cell Reports, ISSN 2211-1247, 08/2016, Volume 16, Issue 8, pp. 2087 - 2101
Invasive lobular carcinoma (ILC) is an aggressive breast cancer subtype with poor response to chemotherapy. Besides loss of E-cadherin, a hallmark of ILC,... 
Cre-lox | metastasis | classical invasive lobular carcinoma | PTEN | BEZ235 | breast cancer | tumor microenvironment | E-cadherin | genetically engineered mouse model | Journal Article | BREAST-CANCER | INACTIVATION | DISSEMINATION | LEADS | RESISTANCE | MUTATIONS | INHIBITOR | EXPRESSION | TUMORS | GLAND | CELL BIOLOGY | Carcinoma, Lobular - pathology | Receptors, Estrogen - metabolism | Gene Expression Regulation, Neoplastic | Tumor Microenvironment | Gene Expression Profiling | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Carcinoma, Lobular - mortality | Mammary Neoplasms, Experimental - genetics | Quinolines - pharmacology | Carcinoma, Lobular - genetics | Mammary Neoplasms, Experimental - pathology | Female | Integrases - metabolism | Antineoplastic Agents - pharmacology | Cadherins - genetics | Mammary Neoplasms, Experimental - drug therapy | PTEN Phosphohydrolase - genetics | Mammary Neoplasms, Experimental - mortality | PTEN Phosphohydrolase - deficiency | Receptors, Estrogen - genetics | Signal Transduction | Cell Survival | Neoplasm Invasiveness | Gene Silencing | Imidazoles - pharmacology | Mice, Knockout | Phosphatidylinositol 3-Kinases - genetics | Animals | Survival Analysis | Cell Line, Tumor | Carcinoma, Lobular - drug therapy | Mice | Integrases - genetics | Cadherins - deficiency
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2016, Volume 11, Issue 7, p. e0159686
MicroRNAs have emerged as ubiquitous post-transcriptional regulators that coordinate many fundamental processes within cells, including those commonly linked... 
BIOMARKERS | TO-MESENCHYMAL TRANSITION | PROGNOSIS | MULTIDISCIPLINARY SCIENCES | PREVENTION | INDUCED MAMMARY-TUMORS | ENERGY RESTRICTION | EXPRESSION | TUMORIGENESIS | PROMOTION PHASE | PROGRESSION | MicroRNAs - antagonists & inhibitors | Caloric Restriction | Humans | Gene Expression Regulation, Neoplastic | MicroRNAs - metabolism | Gene Expression Profiling | Mammary Neoplasms, Experimental - genetics | Breast Neoplasms - metabolism | MCF-7 Cells | Female | Oligoribonucleotides, Antisense - metabolism | Mammary Neoplasms, Experimental - mortality | Mammary Glands, Animal - pathology | Rats | Tumor Burden | Mammary Neoplasms, Experimental - diet therapy | Rats, Sprague-Dawley | Disease Progression | Mammary Neoplasms, Experimental - chemically induced | Disease-Free Survival | Animals | Breast Neoplasms - genetics | Mammary Glands, Animal - metabolism | Breast Neoplasms - pathology | Oligoribonucleotides, Antisense - genetics | 9,10-Dimethyl-1,2-benzanthracene | MicroRNAs - genetics | Animal experimentation | Care and treatment | Diet therapy | MicroRNA | Low-calorie diet | Breast cancer | Research | Properties | Health aspects | Risk factors | Methods | Cancer | Post-transcription | Regulators | Cancer therapies | Mimicry | Ovarian cancer | Anticancer properties | Rodents | Tumorigenesis | Inhibition | Mammary gland | Anthracene | Nutrient deficiency | MiRNA | Tumor cell lines | Gene expression | Nutrition research | Diet | Ribonucleic acids | MicroRNAs | Cell lines | Prostate | Tumors
Journal Article