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Journal of allergy and clinical immunology, ISSN 0091-6749, 2008, Volume 122, Issue 2, pp. 368 - 374.e2
Background Community-acquired pneumonia (CAP) is the leading cause of death from infection in developed countries. Mannose-binding lectin (MBL) and... 
Allergy and Immunology | primary immunodeficiency | Community-acquired pneumonia | sepsis | mannose-binding lectin | mannose-binding lectin–associated serine protease 2 | mannose-binding lectin-associated serine protease 2 | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Mannose-Binding Lectin - physiology | Prospective Studies | Humans | Middle Aged | Male | Pneumonia, Bacterial - metabolism | Mannose-Binding Lectin - genetics | Case-Control Studies | Pneumonia, Pneumococcal - genetics | Pneumonia, Pneumococcal - physiopathology | Mannose-Binding Protein-Associated Serine Proteases - genetics | Adult | Female | Pneumonia, Bacterial - genetics | Pneumonia, Bacterial - physiopathology | Severity of Illness Index | Genetic Predisposition to Disease | Mannose-Binding Lectin - blood | Gene Frequency | Kaplan-Meier Estimate | Genotype | Mannose-Binding Protein-Associated Serine Proteases - deficiency | Mannose-Binding Protein-Associated Serine Proteases - analysis | Polymorphism, Genetic | Community-Acquired Infections - genetics | Pneumonia, Pneumococcal - metabolism | Alleles | Aged | Mannose-Binding Lectin - deficiency | Lectins | Pneumonia | Disease susceptibility | Proteases | Serine | Bacterial pneumonia | Chronic obstructive pulmonary disease | Respiratory distress syndrome | Drug therapy | Mortality | Index Medicus | Abridged Index Medicus
Journal Article
PloS one, ISSN 1932-6203, 02/2010, Volume 5, Issue 2, pp. e8433 - e8433
Background: The complement system is a major effector of innate immunity that has been involved in stroke brain damage. Complement activation occurs through... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Immunohistochemistry | Humans | Middle Aged | Brain Ischemia - genetics | Brain Ischemia - metabolism | Male | Mannose-Binding Lectin - genetics | Stroke - genetics | Stroke - pathology | Mannose-Binding Protein-Associated Serine Proteases - genetics | Aged, 80 and over | Female | Cell Line | Complement C3 - metabolism | Mice, Inbred C57BL | Genotype | Logistic Models | Recombinant Proteins - pharmacology | Blotting, Western | Mice, Knockout | Mannose-Binding Lectin - metabolism | Stroke - metabolism | Animals | Signal Transduction - drug effects | Brain Ischemia - pathology | Aged | Mice | Mannose-Binding Lectin - deficiency | Stroke (Disease) | Proteases | Lectins | Brain damage | Research | Sugars | Genetic polymorphisms | Monosaccharides | Brain | Neurosciences | Heart attacks | Traumatic brain injury | Serine | Innate immunity | Mannose | Gene polymorphism | Immunity | Medical schools | Proteins | Immunology | Reperfusion | Ischemia | E coli | Neurodegeneration | Rodents | Mannose-binding lectin | Genotypes | Binding | Stroke | Inflammation | Mannose-binding protein-associated serine proteinase | MASP-2 protein | Complement activation | Cellular biology | Complement component C4 | Complement component C3 | Infiltration | Brain injury | Polymorphism | Veins & arteries | Index Medicus | Infart cerebral | Immunitat | Cerebral infarctio | Models animals en la investigació | Animal models in research | Proteolytic enzymes | Enzims proteolítics
Journal Article
Journal Article
Journal Article
Journal Article
Nature (London), ISSN 1476-4687, 11/2018, Volume 563, Issue 7733, pp. 719 - 723
It is now well established that tumours undergo changes in cellular metabolism(1). As this can reveal tumour cell vulnerabilities and because many tumours... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Neoplasms - metabolism | Apoptosis - drug effects | Humans | Mannose - administration & dosage | Myeloid Cell Leukemia Sequence 1 Protein - metabolism | Body Weight - drug effects | Antineoplastic Agents - therapeutic use | Mannose-6-Phosphate Isomerase - genetics | Glycolysis - drug effects | Mannose - therapeutic use | Mannose - metabolism | Mannose-6-Phosphate Isomerase - deficiency | RNA Interference | Biomarkers, Tumor - metabolism | Female | Antineoplastic Agents - pharmacology | Administration, Oral | Mice, Inbred C57BL | Neoplasms - classification | Mannose-6-Phosphate Isomerase - metabolism | Down-Regulation - drug effects | Neoplasms - drug therapy | Drug Synergism | Animals | Mannosephosphates - metabolism | Mice, Nude | Cell Line, Tumor | Glucose - metabolism | Cell Proliferation - drug effects | Mannose - pharmacology | Mice | Neoplasms - pathology | bcl-X Protein - metabolism | Chemotherapy | Methods | Cancer | Phosphates | Tricarboxylic acid cycle | Growth rate | Bcl-2 protein | Mannose | Glucose | Kinases | Autophagy | Monosaccharides | Proteins | Glucose metabolism | Cell growth | Pentose | Sugar | Glucose transporter | Pentose phosphate | RNA-mediated interference | Oral administration | Metabolism | Ribonucleic acid--RNA | Chromatography | Weight | Glycan | Depletion | Cell death | Pentose phosphate pathway | Glycolysis | Biomarkers | Transporter | Tumors | Apoptosis | Index Medicus
Journal Article
Immunobiology, ISSN 0171-2985, 2010, Volume 216, Issue 1, pp. 96 - 102
Abstract The first line of host defense is the innate immune system that includes coagulation factors and pattern recognition molecules, one of which is... 
Allergy and Immunology | Advanced Basic Science | Infection | MASP | Inflammation | Deficiency | Mannose-binding lectin | Coagulation | Life Sciences & Biomedicine | Immunology | Science & Technology | Disseminated Intravascular Coagulation - genetics | Mannose-Binding Protein-Associated Serine Proteases - immunology | Liver - pathology | Mannose-Binding Lectin - immunology | Liver - microbiology | Adoptive Transfer | Mannose-Binding Lectin - genetics | Liver - immunology | Mannose-Binding Protein-Associated Serine Proteases - genetics | Disseminated Intravascular Coagulation - epidemiology | Interleukin-6 - metabolism | Thrombin - immunology | Mannose-Binding Protein-Associated Serine Proteases - metabolism | Staphylococcal Infections - genetics | Disease Susceptibility | Interleukin-6 - genetics | Staphylococcal Infections - immunology | Liver - metabolism | Mice, Inbred C57BL | Risk Factors | Complement Pathway, Mannose-Binding Lectin - genetics | Staphylococcus aureus - pathogenicity | Mice, Knockout | Mannose-Binding Lectin - metabolism | Animals | Staphylococcal Infections - epidemiology | Staphylococcal Infections - physiopathology | Blood Coagulation - genetics | Staphylococcus aureus - immunology | Disseminated Intravascular Coagulation - immunology | Disseminated Intravascular Coagulation - physiopathology | Mice | Thrombin - metabolism | Index Medicus | infection | deficiency | inflammation | coagulation | mannose-binding lectin
Journal Article
Immunobiology, ISSN 0171-2985, 2015, Volume 221, Issue 2, pp. 175 - 181
Highlights • MBL2 gene mutations and low MBL concentrations may protect patients from SIRS. • Low MBL-MASP-2 activities may protect from SIRS, LCOS and MOF. •... 
Allergy and Immunology | Advanced Basic Science | Mannan-binding lectin | SIRS | Mannose-binding lectin (MBL) | Complement | Congenital heart disease | Cardiopulmonary bypass (CPB) | Life Sciences & Biomedicine | Immunology | Science & Technology | Cardiac Output - physiology | Mannose-Binding Protein-Associated Serine Proteases - immunology | Postoperative Complications - etiology | Prospective Studies | Mannose-Binding Lectin - immunology | Cardiopulmonary Bypass - adverse effects | Humans | Child, Preschool | Infant | Male | Mannose-Binding Lectin - genetics | Postoperative Complications - immunology | Cardiac Output, Low - immunology | Protective Factors | Cardiac Output, Low - etiology | Mannose-Binding Protein-Associated Serine Proteases - genetics | Postoperative Complications - genetics | Female | Immunologic Deficiency Syndromes - blood | Immunologic Deficiency Syndromes - immunology | Child | Mannose-Binding Protein-Associated Serine Proteases - metabolism | Postoperative Complications - pathology | Metabolism, Inborn Errors - blood | Gene Expression | Mannose-Binding Lectin - blood | Cardiac Output, Low - pathology | Cardiac Output, Low - genetics | Risk Factors | Genotype | Mannose-Binding Protein-Associated Serine Proteases - deficiency | Metabolism, Inborn Errors - genetics | Metabolism, Inborn Errors - immunology | Adolescent | Immunologic Deficiency Syndromes - genetics | Mannose-Binding Lectin - deficiency | Lectins | Pediatrics | Children | Health aspects | Sugars | Monosaccharides | Medical research | Genetic disorders | Genes | Risk factors | Coronary artery bypass | Gene mutations | Proteases | Medicine, Experimental | Research institutes | Heart diseases | Index Medicus
Journal Article