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1. Full Text Mycobacterial lipoarabinomannans modulate cytokine production in human T helper cells by interfering with raft/microdomain signalling
by Shabaana, A K and Kulangara, K and Semac, I and Parel, Y and Ilangumaran, S and Dharmalingam, K and Chizzolini, C and Hoessli, D C
CMLS Cellular and Molecular Life Sciences, ISSN 1420-682X, 1/2005, Volume 62, Issue 2, pp. 179 - 187
Lipoarabinomannans (LAMs) are major lipoglycans of the mycobacterial envelope and constitute immunodominant epitopes of mycobacteria. In this paper, we show... 
Life Sciences | Biochemistry, general | Th1/Th2 | cytokine | lipoarabinomannan | Life Sciences, general | raft | Biomedicine general | signalling | Cell Biology | Raft | Signalling | Cytokine | Lipoarabinomannan | PLASMA-MEMBRANES | PROTEIN-KINASE-C | HUMAN MACROPHAGES | BIOCHEMISTRY & MOLECULAR BIOLOGY | lipoarabinomarman | RECEPTOR | TYROSINE KINASES | CELL BIOLOGY | TUBERCULOSIS LIPOARABINOMANNAN | LIPID RAFTS | MEDIATED ACTIVATION | Th 1/Th2 | DOMAINS | LYMPHOCYTES | Membrane Glycoproteins - metabolism | Mycobacterium - immunology | Signal Transduction | Membrane Microdomains - metabolism | Humans | Membrane Glycoproteins - chemistry | Membrane Microdomains - chemistry | Molecular Sequence Data | Th2 Cells - immunology | Th1 Cells - immunology | Th2 Cells - chemistry | Interleukins - metabolism | Mannose - metabolism | Base Sequence | Lipopolysaccharides - pharmacology | Mycobacterium - chemistry | Th1 Cells - chemistry | Cytokines - biosynthesis | Mannose - chemistry | Growth factors | Cytokines | T cell receptors | Bacteriology
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2. Full Text A Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan Shield
by Robert Pejchal and Katie J. Doores and Laura M. Walker and Reza Khayat and Po-Ssu Huang and Sheng-Kai Wang and Robyn L. Stanfield and Jean-Philippe Julien and Alejandra Ramos and Max Crispin and Rafael Depetris and Umesh Katpally and Andre Marozsan and Albert Cupo and Sebastien Maloveste and Yan Liu and Ryan McBride and Yukishige Ito and Rogier W. Sanders and Cassandra Ogohara and James C. Paulson and Ten Feizi and Christopher N. Scanlan and Chi-Huey Wong and John P. Moore and William C. Olson and Andrew B. Ward and Pascal Poignard and William R. Schief and Dennis R. Burton and Ian A. Wilson
Science, ISSN 0036-8075, 11/2011, Volume 334, Issue 6059, pp. 1097 - 1103
The HIV envelope (Env) protein gpl20 is protected from antibody recognition by a dense glycan shield. However, several of the recently identified PGT broadly... 
Polysaccharides | HIV | Neutralizing antibodies | RESEARCH ARTICLES | Antibodies | Viruses | Trimers | Epitopes | Grants | Binding sites | Crystal structure | PANEL | TRIMERS | MULTIDISCIPLINARY SCIENCES | IMMUNOGENS | ENVELOPE GLYCOPROTEIN COMPLEX | GP120 | HUMAN-IMMUNODEFICIENCY-VIRUS | MONOCLONAL-ANTIBODIES | TYPE-1 | Antibody Specificity | Mannose - immunology | Disaccharides - metabolism | Humans | Antibodies, Neutralizing - metabolism | Crystallography, X-Ray | Disaccharides - chemistry | Mannosides - chemistry | HIV Envelope Protein gp120 - metabolism | HIV Envelope Protein gp120 - immunology | Mannose - metabolism | Antibodies, Neutralizing - immunology | HIV-1 - physiology | HIV Antibodies - immunology | Immunoglobulin Fab Fragments - metabolism | Oligosaccharides - chemistry | Polysaccharides - chemistry | HIV Envelope Protein gp120 - chemistry | Mannose - chemistry | HIV Antibodies - metabolism | Protein Structure, Tertiary | Cell Line | Models, Molecular | Antibodies, Neutralizing - genetics | Glycosylation | Polysaccharides - immunology | Oligosaccharides - metabolism | HIV Antibodies - chemistry | Polysaccharides - metabolism | HIV-1 - immunology | Hydrogen Bonding | Antibodies, Neutralizing - chemistry | Immunoglobulin Fab Fragments - chemistry | Oligosaccharides - immunology | Protein Conformation | Mannosides - metabolism | HIV Antibodies - genetics | Immunoglobulin Fab Fragments - immunology | Mutation | Binding Sites, Antibody | Carbohydrate Conformation | Viral antibodies | Physiological aspects | Development and progression | Glycoproteins | HIV (Viruses) | Health aspects | Proteins | Antigens | Immunoglobulins | Human immunodeficiency virus--HIV
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3. Full Text Influence of aglycone structures on N-glycan processing reactions in the endoplasmic reticulum
by Totani, Kiichiro and Yamaya, Kenta and Hirano, Makoto and Ito, Yukishige
Carbohydrate Research, ISSN 0008-6215, 02/2017, Volume 439, pp. 16 - 22
Glycoprotein N-linked oligosaccharides in the endoplasmic reticulum function as tags to regulate glycoprotein folding, sorting, secretion and degradation.... 
Calreticulin | Glucosidase | Glucosyl transferase | Mannosidase | High-mannose glycan | Aglycone specificity | GLUCOSE-GLYCOPROTEIN-GLUCOSYLTRANSFERASE | UDP-GLUCOSE | SOLUBLE BODIPY DERIVATIVES | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | ER-ASSOCIATED DEGRADATION | QUALITY-CONTROL | SUBSTRATE RECOGNITION | PROTEIN-FOLDING SENSOR | BIOSYNTHESIS | CHEMISTRY, APPLIED | MANNOSE TRIMMING STEP | Mannosidases - chemistry | Cell Fractionation | Glucosidases - metabolism | Glycoproteins - metabolism | Endoplasmic Reticulum - metabolism | Fluorescent Dyes - metabolism | Male | Mannosidases - metabolism | Hepatocytes - metabolism | Acetylglucosamine - metabolism | Glucosidases - chemistry | Glucosyltransferases - metabolism | Mannose - metabolism | Endoplasmic Reticulum - chemistry | Calreticulin - metabolism | Glycoproteins - chemistry | Mannose - chemistry | Boron Compounds - chemistry | Carbohydrate Sequence | Fluorescent Dyes - chemistry | Boron Compounds - metabolism | Liver - metabolism | Mice, Inbred C57BL | Glycosylation | Acetylglucosamine - chemistry | Liver - chemistry | Calreticulin - chemistry | Animals | Glucose - chemistry | Glucosyltransferases - chemistry | Glucose - metabolism | Hydrophobic and Hydrophilic Interactions | Protein Conformation | Hepatocytes - chemistry | Mice | Glycoproteins | Dextrose | Glucose
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4. Full Text Characterization and immunomodulatory activities of polysaccharides from Spirogyra neglecta (Hassall) Kützing
by Surayot, Utoomporn and Wang, JianGuo and Lee, Ju Hun and Kanongnuch, Chartchai and Peerapornpisal, Yuwadee and You, SangGuan
Bioscience, Biotechnology, and Biochemistry, ISSN 0916-8451, 10/2015, Volume 79, Issue 10, pp. 1644 - 1653
Sulfated polysaccharides (SP) isolated from freshwater green algae, Spirogyra neglecta (Hassall) Kützing, and fractionated SPs were examined to investigate... 
sulfated polysaccharides | NF-κB | MAPK | Spirogyra | immunostimulation | Sulfated polysaccharides | Immunostimulation | ECKLONIA-CAVA | BIOCHEMISTRY & MOLECULAR BIOLOGY | FOOD SCIENCE & TECHNOLOGY | MOLECULAR CHARACTERISTICS | KAPPA-B | IN-VITRO | NF-kappa B | P38 | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | CAPSOSIPHON-FULVESCENS | CHEMISTRY, APPLIED | ULVA-PERTUSA | ERK | Rhamnose - chemistry | Fucose - chemistry | Plant Extracts - chemistry | Immunologic Factors - isolation & purification | NF-kappa B - immunology | Xylose - chemistry | Polysaccharides - isolation & purification | Sulfates - chemistry | Glucosides - chemistry | Polysaccharides - chemistry | Mitogen-Activated Protein Kinases - immunology | Cytokines - genetics | Macrophages - immunology | Cytokines - immunology | Mannose - chemistry | NF-kappa B - agonists | Cell Line | Nitric Oxide - biosynthesis | Nitric Oxide - immunology | Uronic Acids - isolation & purification | Arabinose - chemistry | Immunologic Factors - chemistry | Algal Proteins - chemistry | Cytokines - agonists | Gene Expression Regulation | Macrophages - cytology | Polysaccharides - pharmacology | Uronic Acids - chemistry | Galactose - chemistry | Animals | NF-kappa B - genetics | Spirogyra - chemistry | Glucose - chemistry | Algal Proteins - isolation & purification | Macrophages - drug effects | Mitogen-Activated Protein Kinases - genetics | Mice | Immunologic Factors - pharmacology
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5. Full Text Chemical properties and antioxidant activity of a water-soluble polysaccharide from Dendrobium officinale
by Luo, Xuan and Luo, Qiu-lian and Tang, Zhuan-hui and Zhang, Xue-feng and Zhong, Yong-hong and Yao, Su-zhi and Wang, Li-sheng and Lin, Cui-wu
International Journal of Biological Macromolecules, ISSN 0141-8130, 08/2016, Volume 89, pp. 219 - 227
In this report, a water-soluble polysaccharide was obtained from the dried stems of by hot-water (70–75 °C) extraction and 85% ethanol precipitation, and... 
Dendrobium officinale polysaccharide | Antioxidant activity | Structure characterization | IMMUNOLOGICAL ACTIVITY | POLYMER SCIENCE | MOLECULAR-WEIGHT | BIOCHEMISTRY & MOLECULAR BIOLOGY | PURIFICATION | DEXTRAN | CHEMISTRY, APPLIED | GEL-PERMEATION CHROMATOGRAPHY | STRUCTURAL FEATURES | Plant Extracts - chemistry | Arabinose - chemistry | Chromatography, Ion Exchange | Molecular Weight | Antioxidants - chemistry | Hexuronic Acids - chemistry | Dendrobium - chemistry | Picrates - antagonists & inhibitors | Biphenyl Compounds - antagonists & inhibitors | Antioxidants - isolation & purification | Polysaccharides - isolation & purification | Glucose - chemistry | Solid Phase Extraction | Polysaccharides - chemistry | Plant Stems - chemistry | Carbohydrate Conformation | Chromatography, Gel | Glycosides - chemistry | Mannose - chemistry | Antioxidants | Polysaccharides | Chemical properties
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6. Full Text Drug delivery to inflamed colon by nanoparticles: Comparison of different strategies
by Coco, Régis and Plapied, Laurence and Pourcelle, Vincent and Jérôme, Christine and Brayden, David J and Schneider, Yves-Jacques and Préat, Véronique
International Journal of Pharmaceutics, ISSN 0378-5173, 01/2013, Volume 440, Issue 1, pp. 3 - 12
For inflammatory bowel disease (IBD) treatment, local delivery of molecules loaded in nanoparticles to the inflamed colon could be a promising strategy. The... 
Nanoparticles | Intestinal barrier | PLGA | Colonic delivery | Trimethylchitosan | Intestinal inflammation | Eudragit | TRIMETHYL CHITOSAN | COPOLYMERS | M-CELLS | Eudragit (R) | CARRIERS | FUNCTIONALIZATION | TRANSPORT | IN-VITRO MODEL | SYSTEMS | PHARMACOLOGY & PHARMACY | ORAL DELIVERY | PLGA NANOPARTICLES | Dextran Sulfate | Nanoparticles - chemistry | Humans | Ethylene Oxide - chemistry | Drug Carriers - administration & dosage | Polyethylene Glycols - chemistry | Drug Carriers - chemistry | Intestinal Absorption | Colitis - chemically induced | Female | Colitis - drug therapy | Polyglactin 910 - chemistry | Ovalbumin - chemistry | Lactones - chemistry | Mannose - chemistry | Caco-2 Cells | Inflammatory Bowel Diseases - drug therapy | Lactic Acid - chemistry | Mice, Inbred C57BL | Polymethacrylic Acids - chemistry | Animals | Chitosan - chemistry | Ovalbumin - administration & dosage | Polyglycolic Acid - chemistry | Mice | Nanoparticles - administration & dosage | Cytokines - pharmacology | Drugs | Drug delivery systems | Comparative analysis | Vehicles
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7. Full Text Modular Synthesis of Amphiphilic Janus Glycodendrimers and Their Self-Assembly into Glycodendrimersomes and Other Complex Architectures with Bioactivity to Biomedically Relevant Lectins
by Percec, Virgil and Leowanawat, Pawaret and Sun, Hao-Jan and Kulikov, Oleg and Nusbaum, Christopher D and Tran, Tam M and Bertin, Annabelle and Wilson, Daniela A and Peterca, Mihai and Zhang, Shaodong and Kamat, Neha P and Vargo, Kevin and Moock, Diana and Johnston, Eric D and Hammer, Daniel A and Pochan, Darrin J and Chen, Yingchao and Chabre, Yoann M and Shiao, Tze C and Bergeron-Brlek, Milan and André, Sabine and Roy, René and Gabius, Hans-J and Heiney, Paul A
Journal of the American Chemical Society, ISSN 0002-7863, 06/2013, Volume 135, Issue 24, pp. 9055 - 9077
The modular synthesis of 7 libraries containing 51 self-assembling amphiphilic Janus dendrimers with the monosaccharides d-mannose and d-galactose and the... 
DRUG-DELIVERY-SYSTEMS | UNILAMELLAR VESICLES | BLOCK-COPOLYMERS | LIQUID-CRYSTALLINE PHASES | MULTIVALENT LIGANDS | CARBOHYDRATE DENDRIMERS | CRYO-TRANSMISSION | MOLECULAR SWITCHES | CHEMISTRY, MULTIDISCIPLINARY | MISTLETOE LECTIN | LIGAND-BINDING CHARACTERISTICS | Galactose - metabolism | Dendrimers - metabolism | Humans | Mannose - chemical synthesis | Small Molecule Libraries - metabolism | Azides - chemistry | Chemistry Techniques, Synthetic - methods | Lectins - metabolism | Mannose - metabolism | Lactose - metabolism | Azides - metabolism | Azides - chemical synthesis | Mannose - chemistry | Lactose - chemical synthesis | Models, Molecular | Small Molecule Libraries - chemical synthesis | Dendrimers - chemical synthesis | Galactose - chemical synthesis | Small Molecule Libraries - chemistry | Surface-Active Agents - metabolism | Galactose - chemistry | Dendrimers - chemistry | Lactose - chemistry | Surface-Active Agents - chemistry | Surface-Active Agents - chemical synthesis | Usage | Light scattering | Chemical properties | Research | Electron microscopy | Structure | Methods | Sugars | Monosaccharides | Protein binding | Index Medicus
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8. Full Text Extraction, purification and characterization of polysaccharides from Hawk tea
by Jia, Xuejing and Ding, Chunbang and Yuan, Ming and Yuan, Shu and Zhang, Zhongwei and Chen, Yang’er and Du, Lei
Carbohydrate Polymers, ISSN 0144-8617, 01/2014, Volume 99, pp. 319 - 324
In the present study, the extraction, purification and characterization of polysaccharides from Hawk mature leaf tea (HMP) were investigated. The optimal... 
Response surface methodology | Polysaccharide | Antioxidant activity | Litsea coreana var. lanuginose | DIFFERENT FRACTIONS | POLYMER SCIENCE | ANTIOXIDANT ACTIVITIES | CHEMISTRY, ORGANIC | OPTIMIZATION | CHEMISTRY, APPLIED | Plant Leaves - chemistry | Plant Extracts - chemistry | Arabinose - chemistry | Chromatography, Ion Exchange | Antioxidants - chemistry | Oxidation-Reduction | Ferric Compounds - chemistry | Factor Analysis, Statistical | Litsea - chemistry | Liquid-Liquid Extraction - statistics & numerical data | Galactose - chemistry | Picrates - antagonists & inhibitors | Biphenyl Compounds - antagonists & inhibitors | Antioxidants - isolation & purification | Polysaccharides - isolation & purification | Glucose - chemistry | Polysaccharides - chemistry | Liquid-Liquid Extraction - methods | Beverages | Mannose - chemistry | Antioxidants | Glucose metabolism | Polysaccharides | Glucose | Galactose | Dextrose
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9. Full Text Effect of Steam Treatment on the Properties of Wood Cell Walls
by Yin, Yafang and Berglund, Lars and Salmén, Lennart and Wallenberg Wood Science Center and Centra and Fiber- och polymerteknologi and Biokompositer and KTH and Skolan för kemivetenskap (CHE)
Biomacromolecules, ISSN 1525-7797, 01/2011, Volume 12, Issue 1, pp. 194 - 202
Steam treatment is a hygrothermal method of potential industrial significance for improving the dimensional stability and durability of wood materials. The... 
COMPRESSED WOOD | FT-IR SPECTROSCOPY | POLYMER SCIENCE | NANOINDENTATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | HEAT-TREATED WOOD | MECHANICAL-PROPERTIES | FIBERS | FIBRIL AGGREGATION | DEUTERIUM-EXCHANGE | CRYSTALLINE-STRUCTURE | PERMANENT FIXATION | Picea - ultrastructure | Lignin - chemistry | Cell Wall - chemistry | Hot Temperature | Spectroscopy, Fourier Transform Infrared | Wood - ultrastructure | Picea - chemistry | Xylans - chemistry | Mannans - chemistry | Steam | Wood - chemistry | Polysaccharides - chemistry | Cell Wall - ultrastructure | Glucuronic Acid - chemistry | Mannose - chemistry | Chemical engineering | Surface and colloid chemistry | Yt- och kolloidkemi | Kemiteknik | Fysikalisk kemi | Kemisk process- och produktionsteknik | Chemical Sciences | TEKNIKVETENSKAP | Naturvetenskap | Physical Chemistry | Kemi | Natural Sciences | TECHNOLOGY | Chemical process and manufacturing engineering
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10. Full Text Glycofullerenes Inhibit Viral Infection
by Luczkowiak, Joanna and Muñoz, Antonio and Sánchez-Navarro, Macarena and Ribeiro-Viana, Renato and Ginieis, Anthony and Illescas, Beatriz M and Martín, Nazario and Delgado, Rafael and Rojo, Javier
Biomacromolecules, ISSN 1525-7797, 02/2013, Volume 14, Issue 2, pp. 431 - 437
Water-soluble glycofullerenes based on a hexakis-adduct of [60]fullerene with an octahedral addition pattern are very attractive compounds providing a... 
POLYMERS | POLYMER SCIENCE | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLYCOSYL | CHEMISTRY, ORGANIC | FULLERENE DERIVATIVES | DEPENDENCE | BALLS | DC-SIGN | C-60 | LIPOSOMES | BINDING | EBOLA-VIRUS | Cell Adhesion Molecules - chemistry | Glycoconjugates | Humans | Virion - genetics | Virion - chemistry | Fullerenes - pharmacology | Ebolavirus - genetics | Lectins, C-Type - chemistry | Lectins, C-Type - metabolism | Antiviral Agents - chemistry | HEK293 Cells | Receptors, Cell Surface - chemistry | Fullerenes - chemistry | CD4-Positive T-Lymphocytes - virology | Mannose - chemistry | Antiviral Agents - pharmacology | Jurkat Cells | Virion - physiology | Receptors, Cell Surface - metabolism | Cell Adhesion Molecules - metabolism | Ebolavirus - chemistry | Carbohydrates - chemistry | Cell Line, Tumor | Lectins | Ebolavirus - physiology
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11. Full Text Steering Carbon Nanotubes to Scavenger Receptor Recognition by Nanotube Surface Chemistry Modification Partially Alleviates NFκB Activation and Reduces Its Immunotoxicity
by Gao, Ningning and Zhang, Qiu and Mu, Qingxin and Bai, Yuhong and Li, Liwen and Zhou, Hongyu and Butch, Elizabeth R and Powell, Tremaine B and Snyder, Scott E and Jiang, Guibin and Yan, Bing
ACS Nano, ISSN 1936-0851, 06/2011, Volume 5, Issue 6, pp. 4581 - 4591
Carbon nanotubes (CNTs) cause perturbations in immune systems and limit the application of CNTs in biomedicine. Here we demonstrate that a surface chemistry... 
PULMONARY | scavenger receptor | OXIDATIVE STRESS | PROTEIN | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | TOXICITY | BIODISTRIBUTION | MECHANISMS | surface chemistry modification | CHEMISTRY, MULTIDISCIPLINARY | RESPONSES | IN-VITRO | immunotoxicity | multiwalled carbon nanotubes (MWCNTs) | BINDING | mannose receptor | NF kappa B | Tumor Necrosis Factor-alpha - metabolism | Nanotechnology - methods | Inflammation | NF-kappa B - chemistry | Lectins, C-Type - chemistry | Mannose-Binding Lectins - chemistry | Receptors, Scavenger - chemistry | Macrophages - metabolism | Animals | Interleukin-1beta - metabolism | Nanotubes, Carbon - chemistry | Surface Properties | Nanostructures - chemistry | Protein Binding | Receptors, Cell Surface - chemistry | Lipopolysaccharides - chemistry | Mice | Index Medicus | NFκB
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12. Full Text Tin-containing zeolites are highly active catalysts for the isomerization of glucose in water
by Manuel Moliner and Yuriy Román-Leshkov and Mark E. Davis and Energy Frontier Research Centers (EFRC) and Catalysis Center for Energy Innovation (CCEI)
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2010, Volume 107, Issue 14, pp. 6164 - 6168
The isomerization of glucose into fructose is a large-scale reaction for the production of high-fructose corn syrup (HFCS; reaction performed by enzyme... 
Enzymes | Catalysts | Isomerization | Teeth | Materials | Starches | Catalysis | Zeolites | Sugars | Glucose isomerization | Heterogeneous catalysis | glucose isomerization | FRUCTOSE | heterogeneous catalysis | MULTIDISCIPLINARY SCIENCES | ISOMERASE | Temperature | Tin - chemistry | Glucose - chemistry | Water - chemistry | Molecular Structure | Porosity | Isomerism | Zeolites - chemistry | Fructose - chemistry | Mannose - chemistry | Research | Chemical properties | Glucose | Properties | Dextrose | catalysis (homogeneous), catalysis (heterogeneous), biofuels (including algae and biomass), bio-inspired, hydrogen and fuel cells, materials and chemistry by design, synthesis (novel materials), synthesis (self-assembly), synthesis (scalable processing) | INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY | Physical Sciences
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13. Full Text N-Oxy lipid-based click chemistry for orthogonal coupling of mannan onto nanoliposomes prepared by microfluidic mixing: Synthesis of lipids, characterisation of mannan-coated nanoliposomes and in vitro stimulation of dendritic cells
by Bartheldyová, Eliška and Turánek Knotigová, Pavlína and Zachová, Kateřina and Mašek, Josef and Kulich, Pavel and Effenberg, Roman and Zyka, Daniel and Hubatka, František and Kotouček, Jan and Čelechovská, Hana and Héžová, Renata and Tomečková, Andrea and Mašková, Eliška and Fojtíková, Martina and Macaulay, Stuart and Bystrický, Peter and Paulovičová, Ema and Paulovičová, Lucia and Drož, Ladislav and Ledvina, Miroslav and Raška, Milan and Turánek, Jaroslav
Carbohydrate Polymers, ISSN 0144-8617, 03/2019, Volume 207, pp. 521 - 532
New synthetic aminooxy lipid was designed and synthesized as a building block for the formulation of functionalised nanoliposomes (presenting onto the outer... 
Microfluidic mixing | Mannosylated liposomes | Drug delivery | Dendritic cells | Mannan | Click chemistry – oxime ligation | POLYMER SCIENCE | DRUG-DELIVERY | CHEMISTRY, ORGANIC | ANTIBODY | Click chemistry - oxime ligation | RESPONSES | CANDIDA-ALBICANS | ENHANCE | DISEASE | CHEMISTRY, APPLIED | RECEPTORS | BINDING | ANTIGEN | Adjuvants, Immunologic - pharmacology | Nanoparticles - chemistry | Click Chemistry | Dendritic Cells - immunology | Humans | Lectins, C-Type - immunology | Hydroxylamines - chemistry | Mannans - immunology | Receptors, Cell Surface - immunology | Particle Size | Lipids - chemistry | Liposomes - chemistry | Mannans - pharmacology | Animals | Mannose-Binding Lectins - immunology | Lipids - chemical synthesis | Mannans - chemistry | Antigens, Surface - metabolism | Mice, Inbred BALB C | Candida glabrata - chemistry | Liposomes - pharmacology | Microfluidics - methods | Hydroxylamines - chemical synthesis | Liposomes - immunology
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14. Full Text In vivo delivery of peptides and Toll-like receptor ligands by mannose-functionalized polymeric nanoparticles induces prophylactic and therapeutic anti-tumor immune responses in a melanoma model
by Silva, Joana M and Zupancic, Eva and Vandermeulen, Gaëlle and Oliveira, Vanessa G and Salgado, Ana and Videira, Mafalda and Gaspar, Manuela and Graca, Luis and Préat, Véronique and Florindo, Helena F
Journal of Controlled Release, ISSN 0168-3659, 01/2015, Volume 198, pp. 91 - 103
We hypothesized that the co-entrapment of melanoma-associated antigens and the Toll-like receptor (TLR) ligands Poly(I:C) and CpG, known to be... 
Nanoparticles | Cancer vaccine | PLGA | Melanoma | Antigen presenting cells | Mannose receptor targeting | TLR | DENDRITIC CELLS | VACCINE DELIVERY | BIODEGRADABLE NANOPARTICLES | MICROSPHERE | CHEMISTRY, MULTIDISCIPLINARY | PLGA-BASED NANOPARTICLES | S. EQUI ANTIGENS | IMMUNOTHERAPY | PHARMACOLOGY & PHARMACY | EXPRESSION | T-LYMPHOCYTES | OVALBUMIN | Oligodeoxyribonucleotides - administration & dosage | gp100 Melanoma Antigen - chemistry | Immunoglobulin G - blood | Nanoparticles - chemistry | Ovalbumin - immunology | Poly I-C - administration & dosage | Granzymes - metabolism | Oligodeoxyribonucleotides - chemistry | Male | gp100 Melanoma Antigen - immunology | Peptides - administration & dosage | MART-1 Antigen - administration & dosage | Cancer Vaccines | Female | Ovalbumin - chemistry | Cytokines - immunology | Disease Models, Animal | Mannose - chemistry | MART-1 Antigen - chemistry | MART-1 Antigen - immunology | Peptides - chemistry | gp100 Melanoma Antigen - administration & dosage | Mice, Inbred C57BL | Toll-Like Receptors - immunology | Mice, Transgenic | Melanoma - pathology | Poly I-C - chemistry | Animals | Ovalbumin - administration & dosage | Tumor Burden - drug effects | Melanoma - drug therapy | Cell Line, Tumor | Ligands | Polymers - chemistry | Nanoparticles - administration & dosage | Immune response | Peptides | Analysis | Immunotherapy | Health aspects | Sugars | Tumors | Monosaccharides
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