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Journal Article
Cancer Research, ISSN 0008-5472, 07/2014, Volume 74, Issue 18, pp. 5057 - 5069
Cancer immunotherapy generally offers limited clinical benefit without coordinated strategies to mitigate the immunosuppressive nature of the tumor... 
ACTIVATION | INHIBITION | MICROENVIRONMENT | ONCOLOGY | ADENOCARCINOMA | INFLAMMATION | KINASE | CSF | POLARIZATION | IPILIMUMAB | PROGRESSION | Receptor, Macrophage Colony-Stimulating Factor - antagonists & inhibitors | Immunotherapy - methods | Receptor, Macrophage Colony-Stimulating Factor - immunology | Adenocarcinoma - pathology | Macrophage Colony-Stimulating Factor - biosynthesis | Mannose-Binding Lectins - biosynthesis | Tissue Array Analysis | Humans | Lectins, C-Type - immunology | Tumor Microenvironment | Deoxycytidine - pharmacology | Lectins, C-Type - biosynthesis | Female | Receptors, Cell Surface - biosynthesis | Carcinoma, Pancreatic Ductal - immunology | Macrophages - immunology | Signal Transduction | Macrophage Colony-Stimulating Factor - antagonists & inhibitors | Adenocarcinoma - immunology | Mice, Inbred C57BL | Pancreatic Neoplasms - pathology | Carcinoma, Pancreatic Ductal - therapy | Random Allocation | Carcinoma, Pancreatic Ductal - pathology | Receptors, Cell Surface - immunology | Macrophage Colony-Stimulating Factor - immunology | Animals | Mannose-Binding Lectins - immunology | Pancreatic Neoplasms - immunology | T-Lymphocytes - immunology | Mice | Deoxycytidine - analogs & derivatives | Cohort Studies | Pancreatic Neoplasms - therapy | macrophage | chemoresistance | pancreatic cancer | cytokines | innate immunity | immune checkpoint
Journal Article
Journal Article
Immunity, ISSN 1074-7613, 08/2011, Volume 35, Issue 2, pp. 260 - 272
Skin-resident dendritic cells (DCs) are well positioned to encounter cutaneous pathogens and are required for the initiation of adaptive immune responses.... 
EPIDERMAL LANGERHANS CELLS | INFECTIONS | CANDIDA-ALBICANS | POSITIVE SELECTION | IMMUNE-RESPONSES | IN-VIVO | CONTACT HYPERSENSITIVITY | HOST-DEFENSE | SELF-ANTIGENS | IMMUNOLOGY | TH17 CELLS | T-Lymphocyte Subsets - immunology | Skin - microbiology | Mannose-Binding Lectins - biosynthesis | Dendritic Cells - immunology | Antigens, Bacterial - immunology | Dendritic Cells - pathology | Lectins, C-Type - biosynthesis | Adoptive Transfer | Candidiasis - microbiology | Th17 Cells - metabolism | Candidiasis - immunology | Candidiasis - pathology | Dendritic Cells - metabolism | Skin - pathology | Disease Models, Animal | Th17 Cells - pathology | Candida albicans - pathogenicity | Lymphocyte Activation | Mice, Inbred C57BL | Antigens, Surface - biosynthesis | Cells, Cultured | Repressor Proteins - genetics | Mice, Transgenic | Basic-Leucine Zipper Transcription Factors - genetics | Candida albicans - immunology | Receptors, Antigen, T-Cell, alpha-beta - genetics | Mice, Knockout | Animals | T-Lymphocyte Subsets - parasitology | T-Lymphocyte Subsets - metabolism | Dendritic Cells - microbiology | Th17 Cells - immunology | Cross-Priming | Mice | T-Lymphocyte Subsets - microbiology | Th17 Cells - microbiology | Antigens | Dendritic cells | T cells | Analysis | Flow cytometry | Skin | Infections | Rodents | Colleges & universities | Immune system | Candida albicans | Candidiasis | Dendritic Cells | Repressor Proteins | Life Sciences | Immunology | Receptors, Antigen, T-Cell, alpha-beta | T-Lymphocyte Subsets | Mannose-Binding Lectins | Lectins, C-Type | Antigens, Bacterial | Th17 Cells | Antigens, Surface | Basic-Leucine Zipper Transcription Factors
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2013, Volume 288, Issue 17, pp. 11761 - 11770
Nonalcoholic fatty liver disease (NAFLD) affects a large proportion of the American population. The spectrum of disease ranges from bland steatosis without... 
TGR5 | DENDRITIC CELLS | FARNESOID X RECEPTOR | MACROPHAGES | BIOCHEMISTRY & MOLECULAR BIOLOGY | KUPFFER CELLS | STEATOHEPATITIS | MICE | SCORING SYSTEM | ALTERNATIVE ACTIVATION | INDUCED INSULIN-RESISTANCE | Liver - pathology | Receptors, G-Protein-Coupled - metabolism | Fatty Liver - pathology | Mannose-Binding Lectins - biosynthesis | Humans | Lectins, C-Type - immunology | Intercellular Signaling Peptides and Proteins - biosynthesis | Male | Monocytes - metabolism | Lectins, C-Type - biosynthesis | Monocytes - immunology | Receptors, G-Protein-Coupled - immunology | Liver - immunology | Receptors, Cytoplasmic and Nuclear - immunology | Monocytes - pathology | Non-alcoholic Fatty Liver Disease | Receptors, Cell Surface - biosynthesis | Cyclic AMP - metabolism | Macrophages - immunology | Fatty Liver - metabolism | Gene Expression Regulation - immunology | Macrophage Activation - immunology | Liver - metabolism | Receptors, Cell Surface - immunology | Macrophages - metabolism | Animals | Mannose-Binding Lectins - immunology | Cyclic AMP - immunology | Fatty Liver - immunology | Interleukin-10 - biosynthesis | Mice, Obese | Mice | Interleukin-10 - immunology | Intercellular Signaling Peptides and Proteins - immunology | Receptors, Cytoplasmic and Nuclear - metabolism | FXR | Monocytes | Immunology | Mouse | Liver | Macrophages | IL-10 | Steatosis
Journal Article
Journal Article
Cellular Immunology, ISSN 0008-8749, 01/2013, Volume 281, Issue 1, pp. 51 - 61
Journal Article
Inflammation, ISSN 0360-3997, 8/2013, Volume 36, Issue 4, pp. 921 - 931
Murine macrophages are activated by interferon-γ (IFN-γ) and/or Toll-like receptor (TLR) agonists such as bacterial endotoxin (lipopolysaccharide [LPS]) to... 
Pathology | alternative activation | Medicine & Public Health | Rheumatology | adenosine receptor | Internal Medicine | macrophage | TLR | Pharmacology/Toxicology | IL-4Rα | ACTIVATION | A(2A) RECEPTORS | C/EBP-BETA | IL-10 PRODUCTION | INJURY | IL-4R alpha | IMMUNOLOGY | MURINE | CELL BIOLOGY | REPAIR | LIPOPOLYSACCHARIDE | TRANSCRIPTIONAL REGULATION | EXPRESSION | Vascular Endothelial Growth Factor A - biosynthesis | Nitric Oxide Synthase Type II - biosynthesis | Mannose-Binding Lectins - biosynthesis | Arginase - biosynthesis | Intercellular Signaling Peptides and Proteins - biosynthesis | Male | Lectins, C-Type - biosynthesis | Lectins - biosynthesis | Interleukin-4 Receptor alpha Subunit - genetics | Cell Differentiation | Receptors, Cell Surface - biosynthesis | Macrophages - immunology | Interleukin-12 - biosynthesis | Interleukin-4 Receptor alpha Subunit - metabolism | Signal Transduction | Purinergic P1 Receptor Agonists - pharmacology | Cells, Cultured | Mice, Transgenic | Adenosine - pharmacology | Receptor, Adenosine A2A - metabolism | beta-N-Acetylhexosaminidases - biosynthesis | Neovascularization, Physiologic - immunology | Macrophage Activation | Animals | Adenosine - metabolism | Interleukin-10 - biosynthesis | Macrophages - drug effects | Mice | Mice, Inbred BALB C | Tumor Necrosis Factor-alpha - biosynthesis | Physiological aspects | Cell receptors | Genetic aspects | Cellular signal transduction | Research | Macrophages | IL4Rα | Alternative Activation | Adenosine Receptor | Macrophage
Journal Article
The Journal of Immunology, ISSN 0022-1767, 05/2007, Volume 178, Issue 10, pp. 6259 - 6267
Journal Article
Journal of Immunology, ISSN 0022-1767, 02/2011, Volume 186, Issue 3, pp. 1377 - 1383
The C-type lectin langerin/CD207 was originally discovered as a specific marker for epidermal Langerhans cells (LC). Recently, additional and distinct subsets... 
EPIDERMAL LANGERHANS CELLS | DNA IMMUNIZATION | IN-VIVO | DISTINCT | CONTACT HYPERSENSITIVITY | LANGERIN/CD207 | SELF-ANTIGENS | SKIN | IMMUNOLOGY | IDENTIFICATION | CROSS-PRESENTATION | CD8-Positive T-Lymphocytes - cytology | Immunoglobulin Heavy Chains - biosynthesis | Skin - cytology | Antigens, CD - biosynthesis | Mannose-Binding Lectins - biosynthesis | Skin - metabolism | Dendritic Cells - immunology | Cell Death - immunology | Vaccines, DNA - immunology | Lectins, C-Type - biosynthesis | Lectins, C-Type - genetics | Antigens, CD - genetics | Vaccines, DNA - administration & dosage | Mannose-Binding Lectins - deficiency | Cell Differentiation - genetics | Lymphocyte Activation - immunology | Cell Death - genetics | T-Lymphocytes, Helper-Inducer - immunology | CD8-Positive T-Lymphocytes - metabolism | Immunoglobulin gamma-Chains - metabolism | Lectins, C-Type - deficiency | Dendritic Cells - metabolism | Skin - immunology | Cytotoxicity, Immunologic - genetics | T-Lymphocytes, Helper-Inducer - metabolism | Immunoglobulin Heavy Chains - classification | Mice, Inbred C57BL | Antigens, Surface - biosynthesis | Antigens, Surface - genetics | Cells, Cultured | Biolistics | Mice, Transgenic | Immunoglobulin gamma-Chains - classification | Immunoglobulin Switch Region - immunology | Cell Differentiation - immunology | Animals | Mannose-Binding Lectins - genetics | Immunoglobulin gamma-Chains - biosynthesis | Immunoglobulin Heavy Chains - metabolism | Immunoglobulin Switch Region - genetics | Mice | Mice, Inbred BALB C | CD8-Positive T-Lymphocytes - immunology | Dendritic Cells | Vaccines, DNA | CD8-Positive T-Lymphocytes | Life Sciences | Immunology | Cell Death | Cell Differentiation | Immunoglobulin gamma-Chains | Mannose-Binding Lectins | Lymphocyte Activation | Lectins, C-Type | T-Lymphocytes, Helper-Inducer | Immunoglobulin Heavy Chains | Immunoglobulin Switch Region | Antigens, Surface | Skin | Antigens, CD | Cytotoxicity, Immunologic
Journal Article