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Toxicon, ISSN 0041-0101, 09/2012, Volume 60, Issue 3, pp. 378 - 384
In April and May 2011, three dogs died and one dog became ill after swimming in Lake IJmeer (The Netherlands). At the time, the lake was infested with the... 
LC-MS/MS | Dihydroanatoxin-a | Anatoxin-a | Phormidium | Bathing water | Homoanatoxin-a | cyanobacteriën | mass-spectrometry | toxinen | swimming water | blue-green-algae | cylindrospermopsin | nederland | oppervlaktewater | homoanatoxin-a | water pollution | netherlands | ijsselmeer | zwemwater | surface water | identification | anatoxin-a | cyanobacteria | toxins | biosynthesis | lake ijssel | waterverontreiniging | fresh-water | microcystin | CYLINDROSPERMOPSIN | TOXINS | IDENTIFICATION | FRESH-WATER | MASS-SPECTROMETRY | BLUE-GREEN-ALGAE | MICROCYSTIN | BIOSYNTHESIS | PHARMACOLOGY & PHARMACY | TOXICOLOGY | Stomach - chemistry | Harmful Algal Bloom | Marine Toxins - toxicity | Bacterial Toxins - pharmacokinetics | Cyanobacteria - metabolism | Bacterial Toxins - toxicity | Tropanes - pharmacokinetics | Marine Toxins - analysis | Tissue Distribution | Netherlands | Gastrointestinal Contents - chemistry | Female | Tropanes - toxicity | Gastrointestinal Contents - microbiology | Bacterial Toxins - analysis | Tropanes - chemistry | Neurotoxicity Syndromes - veterinary | Marine Toxins - pharmacokinetics | Bacterial Toxins - chemistry | Neurotoxicity Syndromes - etiology | Animals | Lakes - microbiology | Marine Toxins - chemistry | Tropanes - analysis | Dogs | Dog Diseases - chemically induced | Stomach - microbiology | Wildlife conservation | Metabolites | Marine toxins | Epoxy resins | Cyanobacteria | Birds | Gulls | Water | Management | Index Medicus | Stomach | Intestines | Lakes | Toxins | Drying
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2010, Volume 107, Issue 20, pp. 9252 - 9257
β-methylamino-L-alanine (BMAA), a neurotoxic nonprotein amino acid produced by most cyanobacteria, has been proposed to be the causative agent of devastating... 
Neurotoxins | Seas | Terrestrial ecosystems | Marine fishes | Mussels | Cyanobacteria | Marine ecosystems | Amyotrophic lateral sclerosis | Toxins | Zooplankton | β-methylamino-L-alanine | Liquid chromatography/mass spectrometry | Bioaccumulation | Baltic Sea | NEURODEGENERATIVE DISEASE | CHAMORRO PEOPLE | FLOUNDER PLATICHTHYS-FLESUS | MULTIDISCIPLINARY SCIENCES | liquid chromatography/mass spectrometry | beta-methylamino-L-alanine | bioaccumulation | AMYOTROPHIC-LATERAL-SCLEROSIS | METHYLAMINO-L-ALANINE | AMINO-ACID | BMAA | cyanobacteria | FLYING FOXES | PARKINSONISM-DEMENTIA | BRAIN | Fishes - metabolism | Marine Toxins - metabolism | Cyanobacteria - chemistry | Humans | North Sea | Chromatography, High Pressure Liquid | Environmental Exposure | Marine Toxins - biosynthesis | Marine Toxins - pharmacokinetics | Invertebrates - chemistry | Amino Acids, Diamino - pharmacokinetics | Food Chain | Tandem Mass Spectrometry | Sweden | Animals | Neurotoxins - biosynthesis | Neurotoxins - pharmacokinetics | Neurotoxins - metabolism | Zooplankton - chemistry | Amino Acids, Diamino - metabolism | Amino Acids, Diamino - biosynthesis | Demographic aspects | Physiological aspects | Causes of | Nervous system | Degeneration | Research | Health aspects | Neurotoxic agents | Biological Sciences | liquid chromatography | mass spectrometry | Naturvetenskap | växtfysiologi | Biologiska vetenskaper | Plant Physiology | Natural Sciences
Journal Article
The Journal of Clinical Pharmacology, ISSN 0091-2700, 11/2014, Volume 54, Issue 11, pp. 1239 - 1246
Pediatric drug development is challenging when a product is studied for a pediatric disease that has a different underlying etiology and pathophysiology... 
pharmacokinetics | clinical trial design | neurogenic bladder | pediatric urology | Pediatric urology | Clinical trial design | Pharmacokinetics | Neurogenic bladder | N-OF-1 TRIALS | SPINA-BIFIDA | MANAGEMENT | PHARMACOLOGY & PHARMACY | CHILDREN | Cresols - therapeutic use | Mandelic Acids - pharmacokinetics | Benzhydryl Compounds - administration & dosage | Tablets | Area Under Curve | Humans | Child, Preschool | Quinazolines - pharmacokinetics | Infant | Muscarinic Antagonists - therapeutic use | Adrenergic alpha-1 Receptor Antagonists - administration & dosage | Marine Toxins - therapeutic use | Phenylpropanolamine - therapeutic use | Adrenergic alpha-1 Receptor Antagonists - therapeutic use | Mandelic Acids - therapeutic use | Tolterodine Tartrate | Quinazolines - administration & dosage | Muscarinic Antagonists - pharmacokinetics | Oxocins - therapeutic use | Benzhydryl Compounds - therapeutic use | Child | Benzhydryl Compounds - pharmacokinetics | Cresols - administration & dosage | Mandelic Acids - administration & dosage | Adrenergic alpha-1 Receptor Antagonists - pharmacokinetics | Marine Toxins - pharmacokinetics | Urinary Bladder, Neurogenic - drug therapy | Muscarinic Antagonists - administration & dosage | Marine Toxins - administration & dosage | Phenylpropanolamine - administration & dosage | Quinazolines - therapeutic use | Oxocins - administration & dosage | Adolescent | Cresols - pharmacokinetics | Oxocins - pharmacokinetics | Phenylpropanolamine - pharmacokinetics | Delayed-Action Preparations | Physiology, Pathological | Care and treatment | Children | Diagnosis | Analysis | Diseases | Clinical trials | Pharmaceutical industry | Pediatrics
Journal Article
Archives of Toxicology, ISSN 0340-5761, 1/2018, Volume 92, Issue 1, pp. 143 - 156
Journal Article
Journal Article
Toxicon, ISSN 0041-0101, 12/2013, Volume 75, pp. 16 - 26
Journal Article