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1. Full Text Use of and Mortality After Bilateral Mastectomy Compared With Other Surgical Treatments for Breast Cancer in California, 1998-2011
by Kurian, Allison W and Lichtensztajn, Daphne Y and Keegan, Theresa H. M and Nelson, David O and Clarke, Christina A and Gomez, Scarlett L
JAMA, ISSN 0098-7484, 09/2014, Volume 312, Issue 9, pp. 902 - 914
IMPORTANCE: Bilateral mastectomy is increasingly used to treat unilateral breast cancer. Because it may have medical and psychosocial complications, a better... 
BRCA2 MUTATION CARRIERS | SURVIVAL | WOMEN | RATES | MEDICINE, GENERAL & INTERNAL | SATISFACTION | RISK REDUCTION | CONTRALATERAL PROPHYLACTIC MASTECTOMY | OUTCOMES | 20-YEAR FOLLOW-UP | PERCEPTIONS | Elective Surgical Procedures - statistics & numerical data | Breast Neoplasms - surgery | SEER Program | California - epidemiology | Humans | Mastectomy, Segmental - statistics & numerical data | Middle Aged | Risk | Registries - statistics & numerical data | Adult | Breast Neoplasms - mortality | Female | Aged | Radiotherapy, Adjuvant | Cohort Studies | Mastectomy | Medical tests | Usage | Health aspects | Women | Breast cancer | Womens health | Mortality
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2. Full Text Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year results for local control and overall survival from the TARGIT-A randomised trial
by Vaidya, Jayant S, Prof and Wenz, Frederik, Prof and Bulsara, Max, Prof and Tobias, Jeffrey S, Prof and Joseph, David J, Prof and Keshtgar, Mohammed, Prof and Flyger, Henrik L, MD and Massarut, Samuele, MD and Alvarado, Michael, MD and Saunders, Christobel, Prof and Eiermann, Wolfgang, Prof and Metaxas, Marinos, PhD and Sperk, Elena, MD and Sütterlin, Marc, Prof and Brown, Douglas, FRCS and Esserman, Laura, Prof and Roncadin, Mario, MD and Thompson, Alastair, Prof and Dewar, John A, Prof and Holtveg, Helle M R, MD and Pigorsch, Steffi, MD and Falzon, Mary, FRCPath and Harris, Eleanor, MD and Matthews, April, BSc and Brew-Graves, Chris, MSc and Potyka, Ingrid, PhD and Corica, Tammy, BSc and Williams, Norman R, PhD and Baum, Michael, Prof and TARGIT Trialists Grp and TARGIT trialists' group
Lancet, The, ISSN 0140-6736, 2014, Volume 383, Issue 9917, pp. 603 - 613
Summary Background The TARGIT-A trial compared risk-adapted radiotherapy using single-dose targeted intraoperative radiotherapy (TARGIT) versus fractionated... 
Internal Medicine | IRRADIATION | WOMEN | MEDICINE, GENERAL & INTERNAL | LUMPECTOMY PLUS TAMOXIFEN | CONSERVING SURGERY | ENERGY X-RAYS | CLINICAL-TRIALS | RECURRENCE | ADJUVANT RADIOTHERAPY | MULTICENTRICITY | RADIATION-THERAPY | Breast Neoplasms - surgery | Carcinoma, Ductal, Breast - surgery | Radiotherapy - mortality | Neoplasm Recurrence, Local - prevention & control | Humans | Middle Aged | Kaplan-Meier Estimate | Treatment Outcome | Neoplasm Recurrence, Local - mortality | Carcinoma, Ductal, Breast - mortality | Breast Neoplasms - radiotherapy | Intraoperative Care - mortality | Intraoperative Care - methods | Carcinoma, Ductal, Breast - radiotherapy | Radiotherapy - methods | Breast Neoplasms - mortality | Female | Aged | Mastectomy, Segmental - mortality | Mastectomy, Segmental - methods | Care and treatment | Usage | Patient outcomes | Breast cancer | Research | Radiotherapy | Comparative analysis | Radiation therapy | Cancer therapies | Surgery | Medical prognosis | Mortality
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3. Full Text Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: meta-analysis of individual patient data for 8135 women in 22 randomised trials
by EBCTCG (Early Breast Cancer Trialists' Collaborative Group) and EBCTCG and EBCTCG (Early Breast Cancer Trialists' Collaborative Group)
Lancet, The, ISSN 0140-6736, 2014, Volume 383, Issue 9935, pp. 2127 - 2135
Summary Background Postmastectomy radiotherapy was shown in previous meta-analyses to reduce the risks of both recurrence and breast cancer mortality in all... 
Internal Medicine | CLINICAL-PRACTICE GUIDELINES | IRRADIATION | NODES | MEDICINE, GENERAL & INTERNAL | THERAPY | DISSECTION | POSTOPERATIVE RADIOTHERAPY | CONSENSUS | POSTMASTECTOMY RADIOTHERAPY | Lymph Node Excision | Breast Neoplasms - surgery | Breast Neoplasms - radiotherapy | Humans | Neoplasm Recurrence, Local | Axilla | Mastectomy | Breast Neoplasms - mortality | Female | Lymphatic Metastasis | Randomized Controlled Trials as Topic | Usage | Care and treatment | Breast cancer | Research | Radiotherapy | Patient outcomes | Radiation therapy | Womens health | Mortality | Clinical outcomes
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4. Full Text Morbidity and mortality following breast cancer surgery in women: National benchmarks for standards of care
by El-Tamer, Mahmoud B and Ward, B. Marie and Schifftner, Tracy and Neumayer, Leigh and Khuri, Shukri and Henderson, William
Annals of Surgery, ISSN 0003-4932, 05/2007, Volume 245, Issue 5, pp. 665 - 671
Background: Most reports on postoperative (OP) morbidity and mortality following breast cancer surgery (BCS) are limited by relatively small sample size... 
MASTECTOMY | SURGERY | INFECTIONS | SURGICAL RISK | MODELS | OPERATIONS | Body Mass Index | Breast Neoplasms - surgery | United States - epidemiology | Humans | Middle Aged | Risk Factors | Benchmarking | Survival Rate | Treatment Outcome | Mastectomy - mortality | Breast Neoplasms - complications | Adult | Breast Neoplasms - mortality | Female | Aged | Mastectomy - adverse effects | Databases, Factual
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5. Full Text Association of Risk-Reducing Surgery in BRCA1 or BRCA2 Mutation Carriers With Cancer Risk and Mortality
by Domchek, Susan M and Friebel, Tara M and Singer, Christian F and Evans, D. Gareth and Lynch, Henry T and Isaacs, Claudine and Garber, Judy E and Neuhausen, Susan L and Matloff, Ellen and Eeles, Rosalind and Pichert, Gabriella and Van t’veer, Laura and Tung, Nadine and Weitzel, Jeffrey N and Couch, Fergus J and Rubinstein, Wendy S and Ganz, Patricia A and Daly, Mary B and Olopade, Olufunmilayo I and Tomlinson, Gail and Schildkraut, Joellen and Blum, Joanne L and Rebbeck, Timothy R
JAMA, ISSN 0098-7484, 09/2010, Volume 304, Issue 9, pp. 967 - 975
CONTEXT Mastectomy and salpingo-oophorectomy are widely used by carriers of BRCA1 or BRCA2 mutations to reduce their risks of breast and ovarian cancer.... 
BREAST-CANCER | PENETRANCE | MEDICINE, GENERAL & INTERNAL | BILATERAL PROPHYLACTIC OOPHORECTOMY | THERAPY | SALPINGO-OOPHORECTOMY | OVARIAN-CANCER | PREMENOPAUSAL WOMEN | MENOPAUSE | PROSE-STUDY-GROUP | UNDERWENT OOPHORECTOMY | Genetic Predisposition to Disease | Genetic Testing | Prospective Studies | Ovarian Neoplasms - prevention & control | Ovariectomy | Humans | Middle Aged | Fallopian Tubes - surgery | Risk | Ovarian Neoplasms - mortality | Cause of Death | Breast Neoplasms - prevention & control | Ovarian Neoplasms - genetics | Breast Neoplasms - genetics | Adolescent | Genes, BRCA2 | Mastectomy | Adult | Breast Neoplasms - mortality | Female | Aged | Genes, BRCA1 | Mutation | Care and treatment | BRCA mutations | Breast cancer | Genetic aspects | Diagnosis | Research | Health aspects | Risk factors | Womens health | Risk assessment | Mortality | Ovarian cancer
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6. Full Text Increased cardio and cerebrovascular mortality in breast cancer patients treated with postmastectomy radiotherapy – 25 year follow-up of a randomised trial from the South Sweden Breast Cancer Group
by Killander, Fredrika and Anderson, Harald and Kjellén, Elisabeth and Malmström, Per and Cancerepidemiologi and Onkologi och Patologi, MV and Lund University and Oncology and Pathology, MV and Cancer Epidemiology and Lunds universitet
European Journal of Cancer, ISSN 0959-8049, 2014, Volume 50, Issue 13, pp. 2201 - 2210
Abstract Aim of the study To analyse late morbidity and mortality in pre and post-menopausal breast cancer patients treated with postmastectomy radiotherapy,... 
Hematology, Oncology and Palliative Medicine | Side-effect | Breast cancer | Radiotherapy | Cause of death | Heart disease | Cerebrovascular disease | MYOCARDIAL-INFARCTION | TAMOXIFEN | POSTOPERATIVE RADIOTHERAPY | RISK | ISCHEMIC-HEART-DISEASE | WOMEN | ONCOLOGY | INTERNAL MAMMARY | LOCOREGIONAL RADIATION-THERAPY | CARDIOVASCULAR-DISEASE | ADJUVANT RADIOTHERAPY | Cyclophosphamide - administration & dosage | Humans | Middle Aged | Combined Modality Therapy | Antineoplastic Agents, Alkylating - administration & dosage | Neoplasm Recurrence, Local - mortality | Sweden - epidemiology | Breast Neoplasms - therapy | Cerebrovascular Disorders - mortality | Breast Neoplasms - radiotherapy | Cardiovascular Diseases - epidemiology | Cardiovascular Diseases - mortality | Mastectomy | Postmenopause | Breast Neoplasms - mortality | Female | Cerebrovascular Disorders - epidemiology | Neoplasm Recurrence, Local - epidemiology | Neoplasm Staging | Breast Neoplasms - epidemiology | Cancer patients | Postmenopausal women | Patient outcomes | Mortality | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Cancer and Oncology | Medicin och hälsovetenskap | Cancer och onkologi
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7. Full Text Breast-conservation Therapy After Neoadjuvant Chemotherapy Does Not Compromise 10-Year Breast Cancer-specific Mortality
by Arlow, Renee L and Arlow, Renee L and Paddock, Lisa E and Paddock, Lisa E and Niu, Xiaoling and Niu, Xiaoling and Kirstein, Laurie and Kirstein, Laurie and Haffty, Bruce G and Haffty, Bruce G and Goyal, Sharad and Goyal, Sharad and Kearney, Thomas and Kearney, Thomas and Toppmeyer, Deborah and Toppmeyer, Deborah and Stroup, Antoinette M and Stroup, Antoinette M and Khan, Atif J and Khan, Atif J
American journal of clinical oncology, ISSN 0277-3732, 12/2018, Volume 41, Issue 12, pp. 1246 - 1251
Objectives: Neoadjuvant chemotherapy can increase the rate of breastconserving surgery by downstaging disease in patients with breast cancer. The aim of this... 
neoadjuvant chemotherapy | breast cancer | breast-conservation therapy | downstage | WOMEN | IRRADIATION | SURGICAL ADJUVANT BREAST | PREOPERATIVE CHEMOTHERAPY | ONCOLOGY | BODY-IMAGE | RADIATION-THERAPY | Prognosis | Follow-Up Studies | Humans | Middle Aged | Survival Rate | Combined Modality Therapy | Mastectomy - mortality | Breast Neoplasms - therapy | Young Adult | Neoadjuvant Therapy - mortality | Breast Neoplasms - pathology | Adult | Breast Neoplasms - mortality | Female | Aged | Retrospective Studies | Mastectomy, Segmental - mortality | Care and treatment | Patient outcomes | Surgery | Adjuvant treatment | Breast | Breast cancer | Cancer
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8. Full Text Long-Term Cardiovascular Mortality After Radiotherapy for Breast Cancer
by Bouillon, Kim, MD, MPH and Haddy, Nadia, PhD and Delaloge, Suzette, MD and Garbay, Jean-Remy, MD and Garsi, Jerome-Philippe, PhD and Brindel, Pauline, MD, PhD and Mousannif, Abdeddahir, MSc and Lê, Monique G., MD and Labbe, Martine, BSc and Arriagada, Rodrigo, MD, PhD and Jougla, Eric, MD and Chavaudra, Jean, PhD and Diallo, Ibrahima, PhD and Rubino, Carole, MD, PhD and de Vathaire, Florent, PhD
JACC (Journal of the American College of Cardiology), ISSN 0735-1097, 2011, Volume 57, Issue 4, pp. 445 - 452
Objectives This study sought to investigate long-term cardiovascular mortality and its relationship to the use of radiotherapy for breast cancer. Background... 
Cardiovascular | Internal Medicine | causes of death | long-term mortality | long-term risk | radiotherapy | breast cancer | cardiac disease | cardiovascular diseases | International Classification of Diseases | ICD | Institut Gustave Roussy | IGR | internal mammary chain | IMC | CARDIAC & CARDIOVASCULAR SYSTEMS | MYOCARDIAL-INFARCTION | RISK | CARDIAC MORTALITY | RADIATION-THERAPY | LUNG-CANCER | HEART-DISEASE | MORBIDITY | ADJUVANT RADIOTHERAPY | IONIZING-RADIATION | SURVIVORS | Follow-Up Studies | Radiation Injuries - mortality | Humans | Middle Aged | Cause of Death | Time Factors | Heart - radiation effects | Cardiovascular Diseases - mortality | Adult | Female | Retrospective Studies | Chemotherapy, Adjuvant | France | Radiotherapy, Adjuvant | Mastectomy, Segmental - methods | Radiotherapy Dosage | Cardiovascular Diseases - etiology | Risk Assessment | Cancer Care Facilities | Breast Neoplasms - drug therapy | Breast Neoplasms - radiotherapy | Survival Analysis | Breast Neoplasms - mortality | Aged | Cohort Studies | Breast cancer | Radiotherapy | Health aspects | Epidemiology | Mortality | Heart | Medical records | Cardiovascular disease | Statistical methods | Histology | Radiation therapy | Multivariate analysis | Cancer therapies | Patients | Survival analysis | Womens health | Surgery | Medical prognosis | Age
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9. Full Text Patient and tumor characteristics associated with increased mortality in young women (≤40 years) with breast cancer
by Bharat, Ankit and Aft, Rebecca L and Gao, Feng and Margenthaler, Julie A
Journal of Surgical Oncology, ISSN 0022-4790, 09/2009, Volume 100, Issue 3, pp. 248 - 251
Background The goal of the current study is to identify predictors responsible for mortality disparities between young (≤40 years) and older (>40 years) women... 
mortality | breast cancer | young age (≤40 years) | Young age (≤40 years) | Mortality | Breast cancer | young age (<= 40 years) | SURVIVAL | SURGERY | ONCOLOGY | PROGNOSIS | RACE | RECURRENCE | CONSERVING THERAPY | CARCINOMA | AGE | Age Factors | Humans | Mastectomy, Segmental - statistics & numerical data | Middle Aged | Lymphatic Metastasis | Breast Neoplasms - therapy | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Adult | Breast Neoplasms - mortality | Female | Retrospective Studies | Mastectomy - statistics & numerical data | African Continental Ancestry Group
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10. Full Text Breast-conserving surgery with of without radiotherapy: Pooled-analysis for risks of ipsilateral breast tumor recurrence and mortality
by Vinh-Hung, Vincent and Verschraegen, Claire
Journal of the National Cancer Institute, ISSN 0027-8874, 01/2004, Volume 96, Issue 2, pp. 115 - 121
The objective of the study was to investigate whether radiotherapy or its omission after breast-conserving surgery has measurable consequences on local tumor... 
Breast Neoplasms - surgery | Neoplasm Recurrence, Local - prevention & control | Risk Assessment | Humans | Middle Aged | Treatment Outcome | Disease-Free Survival | Breast Neoplasms - radiotherapy | Mastectomy, Segmental | Survival Analysis | Adult | Breast Neoplasms - mortality | Female | Aged | Radiotherapy, Adjuvant
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