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Cancer Research, ISSN 0008-5472, 05/2010, Volume 70, Issue 9, pp. 3494 - 3504
The tropism of breast cancer cells for bone and their tendency to induce an osteolytic phenotype are a result of interactions between breast cancer cells and... 
LYSYL OXIDASE | LUNG-CANCER | TGF-BETA | COLLAGENASE-3 MMP-13 | METASTASIS | HORMONE-RELATED PROTEIN | ONCOLOGY | GENE-EXPRESSION | MATRIX-METALLOPROTEINASE-9 | HUMAN BREAST-CANCER | SQUAMOUS-CELL CARCINOMAS | Bone and Bones - pathology | Up-Regulation | Adenocarcinoma - pathology | Osteoprotegerin - biosynthesis | Bone Neoplasms - secondary | Gene Expression Profiling | Mammary Neoplasms, Experimental - metabolism | Matrix Metalloproteinase 13 - biosynthesis | Bone Neoplasms - metabolism | RNA, Messenger - biosynthesis | Matrix Metalloproteinase 9 - metabolism | Matrix Metalloproteinase 9 - genetics | Bone and Bones - metabolism | Mammary Neoplasms, Experimental - pathology | Female | Mammary Neoplasms, Experimental - enzymology | Osteolysis - pathology | Matrix Metalloproteinase 9 - biosynthesis | Osteoclasts - pathology | Bone Neoplasms - enzymology | Signal Transduction | Osteolysis - genetics | Matrix Metalloproteinase 13 - genetics | RNA, Messenger - genetics | Adenocarcinoma - enzymology | Bone and Bones - enzymology | RANK Ligand - biosynthesis | Osteolysis - metabolism | Matrix Metalloproteinase 13 - metabolism | Animals | Osteolysis - enzymology | Cell Line, Tumor | Matrix Metalloproteinase Inhibitors | Mice | Mice, Inbred BALB C | Osteoclasts - enzymology | Enzyme Activation | Transforming Growth Factor beta - metabolism | Index Medicus
Journal Article
Journal Article
Osteoarthritis and Cartilage, ISSN 1063-4584, 2013, Volume 22, Issue 1, pp. 133 - 144
Summary Objective Interleukin-1β (IL-1β) is involved in the up-regulation of matrix metalloproteinases (MMPs) leading to cartilage degradation. Cannabinoids... 
Rheumatology | Matrix metalloproteinases (MMPs) | Interleukin 1 (IL-1) | Cannabinoid | Tissue inhibitors of matrix metalloproteinases (TIMP) | Cartilage degradation | Chondrocytes | INTERFERON-BETA TREATMENT | RHEUMATOID-ARTHRITIS | COLLAGEN-INDUCED ARTHRITIS | ACTIVATED RECEPTOR-ALPHA | HUMAN ARTICULAR CHONDROCYTES | RHEUMATOLOGY | CYTOKINE PRODUCTION | MESSENGER-RNA | HUMAN OSTEOARTHRITIC CARTILAGE | Tissue inhibitors of matrix | GENE-EXPRESSION | PPAR-GAMMA | ORTHOPEDICS | metalloproteinases (TIMP) | Interleukin-1beta - pharmacology | Tissue Inhibitor of Metalloproteinase-1 - biosynthesis | Humans | Hexuronic Acids | Matrix Metalloproteinase 13 - biosynthesis | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Receptors, Cannabinoid - metabolism | Chondrocytes - drug effects | Glucuronic Acid | Cartilage, Articular - metabolism | Tissue Inhibitor of Metalloproteinase-2 - biosynthesis | Cell Death - drug effects | Chondrocytes - metabolism | Tissue Inhibitor of Metalloproteinases - biosynthesis | Interleukin-1beta - antagonists & inhibitors | Matrix Metalloproteinases - biosynthesis | Drug Evaluation, Preclinical - methods | Matrix Metalloproteinase 13 - genetics | Cells, Cultured | Morpholines - pharmacology | Alginates | Matrix Metalloproteinase 3 - biosynthesis | Naphthalenes - pharmacology | Gene Expression Regulation - drug effects | Cartilage, Articular - pathology | Osteoarthritis, Knee - pathology | Benzoxazines - pharmacology | Matrix Metalloproteinase 3 - genetics | Osteoarthritis, Knee - metabolism | Index Medicus
Journal Article
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 09/2013, Volume 288, Issue 36, pp. 25964 - 25975
Idiopathic pulmonary fibrosis is a devastating lung disorder of unknown etiology. Although its pathogenesis is unclear, considerable evidence supports an... 
RHEUMATOID-ARTHRITIS | PATHOGENESIS | THERAPY | METABOLISM | SYNOVIAL-FLUID | BIOCHEMISTRY & MOLECULAR BIOLOGY | EMPHYSEMA | I COLLAGEN | RELEASE | IDIOPATHIC PULMONARY-FIBROSIS | EXPRESSION | Gene Expression Regulation, Enzymologic - drug effects | Cell Proliferation | Antibiotics, Antineoplastic - pharmacology | Apoptosis - drug effects | Humans | Matrix Metalloproteinase 1 - biosynthesis | Matrix Metalloproteinase 13 - biosynthesis | Oxygen Consumption - physiology | Pulmonary Alveoli - enzymology | Cell Movement - physiology | Mitochondria - genetics | Pulmonary Alveoli - cytology | Hypoxia-Inducible Factor 1, alpha Subunit - biosynthesis | Epithelial Cells - cytology | Matrix Metalloproteinase 1 - genetics | Cell Line | Respiratory Mucosa - cytology | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Matrix Metalloproteinase 13 - genetics | Enzyme Inhibitors - pharmacology | Respiratory Mucosa - enzymology | Mitochondria - metabolism | Enzyme Activation - drug effects | Cell Movement - drug effects | Animals | Gene Expression Regulation, Enzymologic - genetics | Oxygen Consumption - drug effects | Epithelial Cells - enzymology | Bleomycin - pharmacology | Mice | Apoptosis - physiology | Enzyme Activation - genetics | Staurosporine - pharmacology | Index Medicus | Molecular Bases of Disease | Fibrosis | Epithelial Cell | Idiopathic Pulmonary Fibrosis | Hypoxia-inducible Factor (HIF) | Matrix Metalloproteinase (MMP) | Apoptosis
Journal Article
Journal Article
Journal Article
Arthritis Research and Therapy, ISSN 1478-6354, 05/2015, Volume 17, Issue 1, pp. 119 - 119
Introduction: The transcription factor activating enhancer binding protein 2 epsilon (AP-2 epsilon) was recently shown to be expressed during chondrogenesis as... 
CHONDROCYTE HYPERTROPHY | II-COLLAGEN | RAP-DEFICIENT MICE | 13-DEFICIENT MICE | IN-VITRO | ARTICULAR-CARTILAGE | X COLLAGEN | GROWTH-PLATE | RHEUMATOLOGY | HUMAN COLLAGENASE-3 MMP-13 | TRANSCRIPTION FACTOR | Embryonic development | Gene expression | Osteoarthritis | Genes | Stem cells | Protein binding | Index Medicus
Journal Article
Journal Article
Journal Article
by Xing, R and Jin, Y and Sun, L and Yang, L and Li, C and Li, Z and Liu, X and Zhao, J
Clinical and Experimental Immunology, ISSN 0009-9104, 2016, Volume 184, Issue 2, pp. 147 - 158
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovial fibroblast hyperplasia and bone erosion. Fibroblast-like synoviocytes... 
Fibroblast-like synoviocytes | Matrix metalloproteinases | Interleukin-21 | Migration | Invasion | migration | fibroblast-like synoviocytes | invasion | interleukin-21 | matrix metalloproteinases | Humans | Middle Aged | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Phosphatidylinositol 3-Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Cadherins - biosynthesis | Matrix Metalloproteinase 13 - biosynthesis | Enzyme Activation - immunology | CD4-Positive T-Lymphocytes - immunology | Intercellular Adhesion Molecule-1 - biosynthesis | Interleukins - immunology | Killer Cells, Natural - immunology | Adult | Female | Flavonoids - pharmacology | Interleukins - pharmacology | Chromones - pharmacology | Matrix Metalloproteinase 2 - biosynthesis | STAT3 Transcription Factor - metabolism | Fibroblasts - metabolism | Matrix Metalloproteinase 9 - biosynthesis | Enzyme-Linked Immunosorbent Assay | Cells, Cultured | Morpholines - pharmacology | Reverse Transcriptase Polymerase Chain Reaction | Synovial Membrane - metabolism | Matrix Metalloproteinase 3 - biosynthesis | Polycyclic Compounds - pharmacology | Cell Movement - drug effects | Aged | Arthritis, Rheumatoid - immunology | STAT3 Transcription Factor - antagonists & inhibitors | Synovial Membrane - cytology | Rheumatoid factor | Evaluation | Interleukins | Osteoarthritis | Phosphotransferases | Analysis | Fibroblasts | Cytokines | Kinases | Rheumatoid arthritis | Index Medicus | Original | interleukin‐21 | fibroblast‐like synoviocytes
Journal Article
Biomaterials, ISSN 0142-9612, 2015, Volume 77, pp. 1 - 13
Abstract Wound healing by cell transplantation techniques often suffer setbacks due to oxidative stress encountered at injury sites. A porous... 
Advanced Basic Science | Dentistry | PEG–PU porous networks | Engraftment | Neo-vascularization | Wound healing | Anti-oxidant | Bone-marrow stem cells | PEG-PU porous networks | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | CASTOR-OIL | NETWORKS | And-oxidant | ELECTROLYTES | DENSITY | ROS | Superoxide Dismutase - genetics | Superoxide Dismutase - biosynthesis | Oxidative Stress | Apoptosis - drug effects | Biocompatible Materials - chemistry | Humans | Tumor Necrosis Factor-alpha - genetics | Ethers - chemistry | Polyethylene Glycols - chemistry | Stem Cells - cytology | Wound Healing | Stem Cells - metabolism | Matrix Metalloproteinase 13 - biosynthesis | Tissue Scaffolds - chemistry | Stem Cell Transplantation | Interleukins - genetics | Wounds and Injuries - therapy | Interleukins - biosynthesis | Matrix Metalloproteinase 2 - biosynthesis | Bone Marrow Cells - cytology | Catalase - genetics | Polyurethanes - chemistry | Matrix Metalloproteinase 13 - genetics | Mice, Inbred C57BL | Materials Testing | Glutathione Peroxidase - biosynthesis | Cell Adhesion | Glutathione Peroxidase - genetics | Absorbable Implants | Collagen - metabolism | Matrix Metalloproteinase 2 - genetics | Animals | Cell Line, Tumor | Fibroblasts - cytology | Mice | Porosity | Catalase - biosynthesis | Tumor Necrosis Factor-alpha - biosynthesis | Bone Marrow Cells - metabolism | Oxidative stress | Enzymes | Collagen | Stem cells | Protection and preservation | Chemical properties | Polymer industry | Polymers | Gene expression | Bone marrow | Transplantation | Index Medicus | Stresses | Networks | Cytokines | Catalase | Repair | Scaffolds
Journal Article